Universidad Autónoma del Estado de Morelos

Escuela de Estudios Superiores del Jicarero

“FORMATO PICO”

Enfermería Basada en Evidencia

MTRA. Cynthia Alvarado Bacilio

Alumna. Falcón Santoyo Erika

Lic. En enfermería

4° semestre Grupo A
 PREGUNTAS CLINICAS
1. ¿el uso de dieto terapia es importante para personas obesas con
hipertensión arterial?
2. ¿Existe la obesidad materna?
3. ¿Cómo es el estudio y diagnóstico del paciente obeso?
4. ¿Los pacientes con obesidad son más propensos a padecer insuficiencia
cardiaca?
1. ¿El uso de dieto terapia es importante para personas obesas con
hipertensión arterial?

PROTOCOLO DE BUSQUEDA:

P I C O
Población en general Estilos de vida No adoptar ninguna Morbimortalidad
que padece saludables dieta, medida aceptadas cardiovascular
hipertensión arterial ejercicio físico, como saludables
pérdida de peso,
cesación consumo de
tabaco

Fecha de consulta: 16/05/2022

Hora de consulta: 8:55 PM
Aceptados por título: 5
Rechazados por título: 5

Effects of Classic Ketogenic Diet in Children with Refractory Epilepsy: A Retrospective Cohort Study
in Kingdom of Bahrain.

Perna S, Ferraris C, Guglielmetti M, Alalwan TA, Mahdi AM, Guido D, Tagliabue A.Nutrients. 2022
Apr 22;14(9):1744. doi: 10.3390/nu14091744.PMID: 35565714 Free PMC article.

Background: The classic ketogenic diet (cKD) has been used worldwide as an effective therapy for
children with drug-resistant epilepsy. However, there have been no studies performed in Middle
Eastern countries in order to assess the efficacy, side effects, predictor …

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Evaluation of the cellular and extracellular fluid of the body of calves using bio impedancemetry.

Nikitina A, Trushkin V, Kovalev S, Vasilev R, Vasileva S, Gaponova V, Nikitin G.FASEB J. 2022 May;36
Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R3410.PMID: 35560960
At the same time, the level of extracellular fluid in calves from the G1 and the G2 did not differ
significantly and amounted to 7.9 0.8% and 6.28 1.0%, respectively. After the treatment
(diet therapy and enroxil 5%, intramuscularly, at a dose of 1 ml per 20 kg of b …

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The Glycemic Biomarkers in Children with Drug-Resistant Epilepsy on Various Types of

Ketogenic Diet Therapies: A Cross-sectional study.

Teng LY, Lee VW, Murugesu S, Lee JX, Ibrahim NS, Ishak MF, Mohamed AR, Khoo TB.Epilepsia.
2022 May 8. doi: 10.1111/epi.17292. Online ahead of print.PMID: 35527506

OBJECTIVES: To determine the hemoglobin A1c (HbA1c) and modified glucose-ketone index
(mGKI) in children on different types of ketogenic diet (KD) for treatment of drug-resistant
epilepsy with attempts to evaluate their relationships with components of diet regime a …

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Optimizing Nutrition to Enhance the Treatment of Patients With Inflammatory Bowel Disease.

Vasudevan J, DiVincenzo C, Feagins LA.Gastroenterol Hepatol (N Y). 2022 Feb;18(2):95-

103.PMID: 35505813 Free PMC article.

Increased metabolic demand and malabsorption secondary to systemic inflammation, coupled

with significant GI symptoms that lead to reduced oral food intake, may leave patients with IBD
vulnerable to developing malnutrition. The use of diet as therapy for potential i …

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Etiology-based dietary approach for managing hyperkalemia in people with chronic kidney disease.

St-Jules DE, Fouque D.Nutr Rev. 2022 Apr 28:nuac026. doi: 10.1093/nutrit/nuac026. Online ahead
of print.PMID: 35482610
Diet therapy for hyperkalemia in chronic kidney disease (CKD) is at a crossroads: many researchers
and clinicians are no longer recommending the low-potassium diet, which has defined practice for
the last half century, and instead are favoring a high-potassiu …

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Ameliorative Effect of Oxytocin on FBN1 and PEPCK Gene Expression, and Behavioral Patterns in
Rats' Obesity-Induced Diabetes.

Elnagar A, El-Dawy K, El-Belbasi HI, Rehan IF, Embark H, Al-Amgad Z, Shanab O, Mickdam E, Batiha
GE, Alamery S, Fouad SS, Cavalu S, Youssef M.Front Public Health. 2022 Apr 7;10:777129. doi:
10.3389/fpubh.2022.777129. eCollection 2022.PMID: 35462799 Free PMC article.

Four groups of forty male Wistar rats were formed (n = 10): a control group fed basal diet and
intraperitoneal injections of saline; an oxytocin-injected group; a diet-induced obese group fed a
high-fat/high-sugar diet and injected with saline; a diet- …

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Therapeutic Potential of the 4-SURE Diet in Adults with Mild to Moderately Active Ulcerative
Colitis: An Open Label Feasibility Study.

Day AS, Yao CK, Costello SP, Ruszkiewicz A, Andrews JM, Gibson PR, Bryant RV.J Nutr. 2022 Apr
22:nxac093. doi: 10.1093/jn/nxac093. Online ahead of print.PMID: 35451489

BACKGROUND: Diet therapy may bridge the therapeutic gap in ulcerative colitis
(UC). ...CONCLUSIONS: The 4-SURE dietary strategy is considered tolerable and an
acceptable diet by adults with mild to moderately active UC. The dietary teachings achieved the
pres …

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Calorie Restriction with or without Time-Restricted Eating in Weight Loss.

Liu D, Huang Y, Huang C, Yang S, Wei X, Zhang P, Guo D, Lin J, Xu B, Li C, He H, He J, Liu S, Shi L, Xue
Y, Zhang H.N Engl J Med. 2022 Apr 21;386(16):1495-1504. doi:
10.1056/NEJMoa2114833.PMID: 35443107 Clinical Trial.

For 12 months, all the participants were instructed to follow a calorie-restricted diet that consisted
of 1500 to 1800 kcal per day for men and 1200 to 1500 kcal per day for women. ...

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Efficacy and safety of carbohydrate counting versus other forms of dietary advice in patients with
type 1 diabetes mellitus: a systematic review and meta-analysis of randomised clinical trials.

Builes-Montaño CE, Ortiz-Cano NA, Ramirez-Rincón A, Rojas-Henao NA.J Hum Nutr Diet. 2022 Apr
18. doi: 10.1111/jhn.13017. Online ahead of print.PMID: 35436364

Carbohydrate counting is considered the ideal way to calculate meal-related insulin doses as it
allows greater flexibility in diet and could, in some people, reduce the burden of the disease. ...

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Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth.

Yang L, TeSlaa T, Ng S, Nofal M, Wang L, Lan T, Zeng X, Cowan A, McBride M, Lu W, Davidson S,

Liang G, Oh TG, Downes M, Evans R, Von Hoff D, Guo JY, Han H, Rabinowitz JD.Med (N Y). 2022 Feb
11;3(2):119-136. doi: 10.1016/j.medj.2021.12.008.PMID: 35425930

BACKGROUND: Ketogenic diet is a potential means of augmenting cancer therapy. Here, we

explore ketone body metabolism and its interplay with chemotherapy in pancreatic
cancer. ...CONCLUSIONS: Ketogenic diet sensitizes murine pancreatic cancer tumors to cytoto …

ACEPTADO POR TITULO

2. ¿existe la diabetes materna?
PROTOCOLO DE BUSQUEDA:

P I C O
Mujeres embarazadas Optar por estilos de Mujeres embarazadas Evitar la
con diabetes vida saludables no diabéticas morbimortalidad
materna

Fecha de consulta: 16/05/2022

Hora de consulta: 9:00PM
Aceptados por título: 5
Rechazados por título: 4

Recent Experimental Studies of Maternal Obesity, Diabetes during Pregnancy and the
Developmental Origins of Cardiovascular Disease.
Kereliuk SM, Dolinsky VW.Int J Mol Sci. 2022 Apr 18;23(8):4467. doi:
10.3390/ijms23084467.PMID: 35457285 Free PMC article. Review.
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Clinical consequences of gestational diabetes mellitus and maternal obesity as defined by

asian BMI thresholds in Viet Nam: a prospective, hospital-based, cohort study.
Yue S, Thi VTK, Dung LP, Nhu BTH, Kestelyn E, Thuan DT, Thanh LQ, Hirst JE.BMC
Pregnancy Childbirth. 2022 Mar 9;22(1):195. doi: 10.1186/s12884-022-04533-
1.PMID: 35264148 Free PMC article. ACEPTADO POR TITULO

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Male Rat Offspring Are More Impacted by Maternal Obesity Induced by Cafeteria Diet
than Females-Additive Effect of Postweaning Diet.
Tajaddini A, Kendig MD, Prates KV, Westbrook RF, Morris MJ.Int J Mol Sci. 2022 Jan
27;23(3):1442. doi: 10.3390/ijms23031442.PMID: 35163366 Free PMC article.
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Maternal High-Fat Diet During Pre-Conception and Gestation Predisposes Adult Female
Offspring to Metabolic Dysfunction in Mice.
Akhaphong B, Gregg B, Kumusoglu D, Jo S, Singer K, Scheys J, DelProposto J, Lumeng
C, Bernal-Mizrachi E, Alejandro EU.Front Endocrinol (Lausanne). 2022 Jan 17;12:780300.
doi: 10.3389/fendo.2021.780300. eCollection 2021.PMID: 35111136 Free PMC article.

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Trends in percentages of gestational diabetes mellitus attributable to overweight, obesity,

and morbid obesity in regional Victoria: an eight-year population-based panel study.
Mnatzaganian G, Woodward M, McIntyre HD, Ma L, Yuen N, He F, Nightingale H, Xu T,
Huxley RR.BMC Pregnancy Childbirth. 2022 Feb 1;22(1):95. doi: 10.1186/s12884-022-
04420-9.PMID: 35105311 Free PMC article.
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A Predictive Model of Live Birth Based on Obesity and Metabolic Parameters in Patients
With PCOS Undergoing Frozen-Thawed Embryo Transfer.
Jiang X, Liu R, Liao T, He Y, Li C, Guo P, Zhou P, Cao Y, Wei Z.Front Endocrinol
(Lausanne). 2022 Jan 12;12:799871. doi: 10.3389/fendo.2021.799871. eCollection
2021.PMID: 35095766 Free PMC article.
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Maternal Pre-Pregnancy Obesity Combined With Abnormal Glucose Metabolism Further

Increases Adverse Pregnancy Outcomes in Chinese Pregnant Women.
Li MF, Ke JF, Ma L, Wang JW, Zhang ZH, Li JB, Li LX.Front Endocrinol (Lausanne).
2022 Jan 13;12:754406. doi: 10.3389/fendo.2021.754406. eCollection
2021.PMID: 35095754 Free PMC article.
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Association between plasma leptin and cesarean section after induction of labor: a case
control study.
Cowman W, Scroggins SM, Hamilton WS, Karras AE, Bowdler NC, Devor EJ, Santillan
MK, Santillan DA.BMC Pregnancy Childbirth. 2022 Jan 14;22(1):29. doi: 10.1186/s12884-
021-04372-6.PMID: 35031012 Free PMC article.
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Prevalence of and risk factors for excess weight gain in pregnancy: a cross-sectional study
using survey data.
Benham JL, Booth JE, Donovan LE, Leung AA, Sigal RJ, Rabi DM.CMAJ Open. 2021
Dec 14;9(4):E1168-E1174. doi: 10.9778/cmajo.20200276. Print 2021 Oct-
Dec.PMID: 34906992 Free PMC article.

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Brain-Restricted Inhibition of IL-6 Trans-Signaling Mildly Affects Metabolic
Consequences of Maternal Obesity in Male Offspring.
Breuer S, Kasper P, Vohlen C, Janoschek R, Hoffmann T, Appel S, Müller-Limberger E,
Mesaros A, Rose-John S, Garbers C, Müller S, Lackmann JW, Mahabir E, Dötsch J,
Hucklenbruch-Rother E, Bae-Gartz I.Nutrients. 2021 Oct 23;13(11):3735. doi:
10.3390/nu13113735.PMID: 34835991 Free PMC article.
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3. ¿Cuál es el Estudio y diagnóstico del paciente obeso?

PROTOCOLO DE BUSQUEDA:

P I C O
Población en general Distintos tipos de Estudio habitual Grado de control y
que tenga la sospecha estudio morbilidad
de padecer obesidad

Fecha de consulta: 18/05/2022

Hora de consulta: 9:10 pm
Aceptados por título: 4
Rechazados por título: 5

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Mechanisms, Pathophysiology, and Management of Obesity.

Heymsfield SB, Wadden TA.N Engl J Med. 2017 Jan 19;376(3):254-266. doi:
10.1056/NEJMra1514009.PMID: 28099824 Free article. Review. No abstract available.
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Overweight and obesity management strategies.

Kahan S.Am J Manag Care. 2016 Jun;22(7 Suppl):s186-96.PMID: 27356116 Free
article. Review.
Comprehensive lifestyle interventions, including nutrition, physical activity, and behavioral
therapy, are the foundation for clinical obesity management. New tools and treatment
approaches help clinicians provide these interventions and support weight management …
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The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance
from the American Association for the Study of Liver Diseases.
Chalasani N, Younossi Z, Lavine JE, Charlton M, Cusi K, Rinella M, Harrison SA, Brunt
EM, Sanyal AJ.Hepatology. 2018 Jan;67(1):328-357. doi: 10.1002/hep.29367. Epub 2017
Sep 29.PMID: 28714183 Review. No abstract available.
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Guideline Recommendations for Obesity Management.

Ryan DH, Kahan S.Med Clin North Am. 2018 Jan;102(1):49-63. doi:
10.1016/j.mcna.2017.08.006.PMID: 29156187 Review.
It is an obligation for all health care providers to participate in obesity management. This
article discusses obesity guidelines from The Obesity Society; the Endocrine Society; and
the American Association of Clinical Endocrinologists. ...
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European Guidelines for Obesity Management in Adults.

Yumuk V, Tsigos C, Fried M, Schindler K, Busetto L, Micic D, Toplak H; Obesity
Management Task Force of the European Association for the Study of Obesity.Obes Facts.
2015;8(6):402-24. doi: 10.1159/000442721. Epub 2015 Dec 5.PMID: 26641646 Free
PMC article.
A comprehensive obesity management can only be accomplished by a
multidisciplinary obesity management team. We conclude that physicians have a
responsibility to recognise obesity as a disease and help obese patients with appropriat …
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Obesity: definition, comorbidities, causes, and burden.

Apovian CM.Am J Manag Care. 2016 Jun;22(7 Suppl):s176-85.PMID: 27356115 Free
article. Review.
Consumption patterns, urban development, and lifestyle habits influence the prevalence
of obesity. The condition may be the result of disease or pharmacologic treatment. ...A
review of the prevalence and economic consequences of obesity is provided. Potential …
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Prader-Willi Syndrome - Clinical Genetics, Diagnosis and Treatment Approaches: An
Update.
Butler MG, Miller JL, Forster JL.Curr Pediatr Rev. 2019;15(4):207-244. doi:
10.2174/1573396315666190716120925.PMID: 31333129 Free PMC article. Review.
OBJECTIVE: Hyperphagia and obesity with related complications are major causes of
morbidity and mortality in PWS. This report will describe an accurate diagnosis with
determination of specific genetic subtypes, appropriate medical management and best
practice …
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Obesity in Pregnancy: Risks and Management.

Riley L, Wertz M, McDowell I.Am Fam Physician. 2018 May 1;97(9):559-
561.PMID: 29763261 Free article. No abstract available.
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Obesity and pregnancy: mechanisms of short term and long term adverse consequences for
mother and child.
Catalano PM, Shankar K.BMJ. 2017 Feb 8;356:j1. doi:
10.1136/bmj.j1.PMID: 28179267 Free PMC article. Review.
Because 50-60% of overweight or obese women gain more than recommended by Institute
of Medicine gestational weight guidelines, postpartum weight retention increases future
cardiometabolic risks and prepregnancy obesity in subsequent pregnancies. Neonates
of obese …
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Management of overweight and obesity in primary care-A systematic overview of

international evidence-based guidelines.
Semlitsch T, Stigler FL, Jeitler K, Horvath K, Siebenhofer A.Obes Rev. 2019
Sep;20(9):1218-1230. doi: 10.1111/obr.12889. Epub 2019 Jul 8.PMID: 31286668 Free
PMC article.
We searched in PubMed and major guideline databases for all guidelines published in
World Health Organization (WHO) "Stratum A" nations that dealt with adults with
overweight or obesity. ...Most of them concluded that a multidisciplinary team should treat
overweight …
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4. ¿Los pacientes con obesidad son más propensos a padecer insuficiencia
cardiaca?

PROTOCOLO DE BUSQUEDA:

P I C O
Toda persona que Monitorizar los Personas propensas a Evitar gradecer
padezca obesidad de cuidados de padecer insuficiencia insuficiencia cardiaca
cualquier tipo prevención de cardiaca
insuficiencia cardiaca

Fecha de consulta: 18/05/2022

Hora de consulta: 10: pm
Aceptados por título: 2
Rechazados por título: 8

Myocardial ATP depletion detected noninvasively predicts sudden cardiac death risk
in heart failure patients.
Samuel TJ, Lai S, Schär M, Wu KC, Steinberg AM, Wei AC, Anderson M, Tomaselli GF,
Gerstenblith G, Bottomley PA, Weiss RG.JCI Insight. 2022 May 17:e157557. doi:
10.1172/jci.insight.157557. Online ahead of print.PMID: 35579938
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Association of Congenital and Acquired Cardiovascular Conditions With COVID-19

Severity Among Pediatric Patients in the US.
Ehwerhemuepha L, Roth B, Patel AK, Heutlinger O, Heffernan C, Arrieta AC, Sanger T,
Cooper DM, Shahbaba B, Chang AC, Feaster W, Taraman S, Morizono H, Marano
R.JAMA Netw Open. 2022 May 2;5(5):e2211967. doi:
10.1001/jamanetworkopen.2022.11967.PMID: 35579899
The random intercept model showed that the following cardiovascular conditions were
associated with severe COVID-19: cardiac arrest (odds ratio [OR], 9.92; 95% CI, 6.93-
14.20), cardiogenic shock (OR, 3.07; 95% CI, 1.90-4.96), heart surgery (OR, 3.04; 95%
CI, 2.26-4.08), ca …
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Elevated troponin I levels on admission predict long-term mortality in patients with acute
cerebral infarction following thrombolysis.
Huang Y, Shao Y, Wang Y, Shi T.Neurol Sci. 2022 May 17. doi: 10.1007/s10072-022-
06116-6. Online ahead of print.PMID: 35579823
RESULTS: A total of 145 patients with ACI were recruited; 97 (66%), 30 (20%), and 18
(12%) patients had cTnI concentrations < 0.030 (group 1), 0.030-0.10 (group 2), and > 0.10
mug/L (group 3), respectively. cTnI elevation was associated with older age, atrial
fibrillation,

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Using Iterative Pairwise External Validation to Contextualize Prediction Model

Performance: A Use Case Predicting 1-Year Heart Failure Risk in Patients with Diabetes
Across Five Data Sources.
Williams RD, Reps JM, Kors JA, Ryan PB, Steyerberg E, Verhamme KM, Rijnbeek
PR.Drug Saf. 2022 May;45(5):563-570. doi: 10.1007/s40264-022-01161-8. Epub 2022
May 17.PMID: 35579818
Iterative pairwise external validation (IPEV) is a framework that uses a rotating model
development and validation approach to contextualize the assessment of performance
across a network of databases. As a use case, we predicted 1-year risk of heart failure in
pati …
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Left atrial echocardiographic parameters predict the onset of atrial fibrillation: the
SMASH2 scoring system.
Darlington AM, Rodriguez Ziccardi MC, Konda S, Gonzalez-Gonzalez FJ, Nazir NT,
McCauley MD.J Interv Card Electrophysiol. 2022 May 17. doi: 10.1007/s10840-022-
01243-8. Online ahead of print.PMID: 35579783
RESULTS: Baseline characteristics, including age, BMI, presence of hypertension,
hyperlipidemia, diabetes, and heart failure were comparable. Increased left atrial (LA) size
(end systolic major axis in 2-chamber view: AF 4.620.03 vs control 3.790.21, P =0.03),
incre …
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Prognostic value of diastolic function parameters in significant aortic regurgitation: the role
of the left atrial strain.
García Martín A, Abellás Sequeiros M, González Gómez AG, Rincón Díaz LM,
Monteagudo Ruiz JM, Hinojar Baydés R, Moya Mur JL, Zamorano JL, Fernández-Golfín
C.J Echocardiogr. 2022 May 17. doi: 10.1007/s12574-022-00577-6. Online ahead of
print.PMID: 35579751
METHODS: A total of 126 patients with asymptomatic sAR evaluated in the Heart Valve
Clinic were retrospective included. Conventional echocardiographic systolic and diastolic
function parameters were assessed. Left atrial (LA) auto-strain analysis was performed in a
sub-gro …
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Mechanical and interventional support for heart failure with preserved ejection fraction: A
review.
Gordon JS, Blazoski CM, Wood CT, Zuber C, Massey HT, Throckmorton A,
Tchantchaleishvili V.Artif Organs. 2022 May 17. doi: 10.1111/aor.14275. Online ahead of
print.PMID: 35579447 Review.
INTRODUCTION: Restrictive cardiomyopathy (RCM) and hypertrophic cardiomyopathy
(HCM) are two disease processes that are known to progress to heart failure with
preserved ejection fraction (HFpEF). Pharmacologic therapies for HFpEF have not
improved patient outcomes …
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Head-to-head comparison between recommendations by the ESC and

ACC/AHA/HFSA Heart Failure Guidelines.
Bayés-Genís A, Aimo A, Metra M, Anker S, Seferovic P, Rapezzi C, Castiglione V, Núñez
J, Emdin M, Rosano G, Coats AJ.Eur J Heart Fail. 2022 May 17. doi: 10.1002/ejhf.2542.
Online ahead of print.PMID: 35579428 Review.
Recommendations represent the core messages of Guidelines, and are particularly
important when the body of scientific evidence is rapidly growing, as in the case
of heart failure (HF). The main messages from two latest major HF Guidelines, endorsed
by the European S …
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Percutaneous approach to left ventricular assist device decommissioning.

Moroni F, Shah KB, Quader MA, Klein K, Smallfield MC, Parris KE, Gertz ZM.Catheter
Cardiovasc Interv. 2022 May 17. doi: 10.1002/ccd.30230. Online ahead of
print.PMID: 35579199
At midterm follow-up, the three patients who had myocardial function recovery were alive
and had not experienced heart failure-related symptoms or complications.
CONCLUSION: Percutaneous LVAD decommissioning appears to be a safe and effective
approach to LVAD treatm …
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The double anaerobic threshold in heart failure: MECKI score database overview.
Rovai S, Zaffalon D, Cittar M, Felli LF, Salvioni E, Galotta A, Mattavelli I, Carriere C,
Mapelli M, Merlo M, Vignati C, Sinagra G, Agostoni P.ESC Heart Fail. 2022 May 17. doi:
10.1002/ehf2.13920. Online ahead of print.PMID: 35579114
AIMS: In heart failure (HF), anaerobic threshold (AT) may be indeterminable but its
value held a relevant prognostic role. ...
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