Documentos de Académico
Documentos de Profesional
Documentos de Cultura
45
GASTRINA
30
Pg/ml
35
30
DE ACIDO( mE q/h)
8
6
SECRECION
2
8 12 16 20 24 4 8 hrs.
(mmol/Hr)
32 ALIMENT.FICTICIA
ACIDA
24
16
8
0
-60 -45 -30 -15 0 15 30 45 60
ALIMENT.FICTICIA
65
60
GASTRINA
SERICA
55
(pg/ml)
50
45
光面管泡
微管
8
HCl secretion
10
NEURONA COLINERGICA
RGP CELULA
CATECOLAMINAS G
ß
M1 CCK-8
Ach GASTRINA,
H3
CCK
ECL (-)
Ach HISTAMINA
M3 H2
CELULA PARIETAL
Gastric acid output at rest and during
maximal stimulation:
Representative Ranges
Basal Acid Maximal Acid
Condition Output (mEq/h) Output (mEq/h)
Normal 1-5 6 - 40
Gastric Ulcer 0-3 1 - 20
Pernicious Anemia (Loss of
0 0 - 10
Parietal Cells)
Duodenal Ulcer 2 - 10 15 - 60
Gastrin-Secreting Tumor
10 - 30 30 - 80
(Zollinger-Ellison Syndrome)
Output = Hourly volume of gastric juice x [H+]
MECANISMOS DE CITOPROTECCION GASTRICA
Defensinas-β
30 millones de celulas/hora
MOCO GASTRICO:5% GLICOPROTEINA,95% AGUA
VISCOSIDAD:30 A 269 VECES AL DEL AGUA