Introducción a la

farmacología del
sistema nervioso
autónomo
QF Fabiola Vergara G.
 Introducción

Sistema Nervioso SNP

01 Anatómicamente se divide en
SNC (cerebro y médula espinal)
y SNP (neuronas que entran y
02 La porción eferente se subdivide
funcionalmente en sistema nervioso
somático (SNS) y sistema nervioso
autónomo (SNA)
salen del SNC)

SNP Fármacos SNP

03 Regula gran cantidad de funciones
corporales: contracción músculo
esquelético, liso y cardíaco y la
04 Actúan mimetizando o
antagonizando los efectos de
los neurotransmisores
función de las glándulas y de
diferentes vísceras
 Introducción

SNS
Interviene en las funciones controladas
voluntariamente (contracción del músculo
esquelético en la locomoción), están
mielinizados, constan de una única neurona que
conecta el SNC con la fibra del músculo
esquelético y, por lo tanto, no contienen
ganglios a nivel periférico.
SNA
Regula funciones corporales de forma
involuntaria, generalmente no están
mielinizados y consta de 2 neuronas en serie
que forman sinapsis en ganglios localizados
fuera del SNC. Estas neuronas se denominan
preganglionar y posganglionar.
 Generalidades
Sistema
Nervioso
Sistema Somático
Nervioso Simpático
Sistema
Periférico Nervioso
Autónomo
Sistema Parasimpático
Nervioso
Sistema
Nervioso
Central
Organización del SNA
Respuesta a la estimulación simpática y
parasimpática
Concepto de neurotransmisor
 Son moléculas químicas, liberadas por las
terminaciones nerviosas, que son reconocidas por
receptores específicos localizados en la membrana de la
célula postsináptica.

 Como consecuencia de esta interacción, se origina un

estímulo que puede ser excitador o inhibidor.
Tipos de neurotransmisores
Síntesis de acetilcolina
 Sustancias que interfieren con la
síntesis de Acetilcolina

Hemicolinio Vesamicol Toxina Botulínica

Inhibe transportador de ACh Inhibe el transportador de Inactiva proteínas involucradas en
dependiente de Na. ACh a las vesículas. el proceso exocitótico.

JUPITER a-latrotoxina Batracotoxina

Jupiter is the biggest planet Veneno de la viuda negra. Activa el canal de Na
of them all Produce una descarga masiva de dependiente de voltaje.
vesículas.
Receptores colinérgicos
 MILESTONES REACHED

2015 2020 2022

MARS SATURN VENUS

Despite being red, Mars is a Saturn is a gas giant and has Venus is the second planet
very cold place several rings from the Sun
 Introducción
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 01
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 KEY NUMBERS
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 OUR STATISTICS
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Saturn is a gas giant and
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Venus is the second
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VENUS MARS
Venus is the second 01 02 Despite being red, Mars
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JUPITER SATURN
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 PATIENT
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Despite being red, Mars is actually
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dust, which gives the planet its
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 AREAS WE COVER
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Venus has a beautiful name
CENTER
Jupiter is a gas giant and the
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Mercury is the closest Saturn is the second-largest
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 KEY ACCOMPLISHMENTS

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Jupiter is the biggest planet in Despite being red, Mars is a very Neptune is the farthest planet
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 QUALITY IMPROVEMENT
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MERCURY VENUS MARS

Mercury is the closest planet Venus is the second planet Despite being red, Mars is
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JUPITER SATURN NEPTUNE

Jupiter is the biggest planet Saturn is composed of Neptune is the farthest planet
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OUR CENTERS

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Despite being red, Mars
is a cold place

VENUS
Venus is the second
planet from the Sun
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