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8th Grade

FENILCETONURIA
Historia de la
fenilcetonuria

La fenilcetonuria es un trastorno metabólico hereditario que se


caracteriza por la acumulación de fenilalanina en el cuerpo. Fue
descubierto por primera vez en 1934 por el Dr. Asbjörn Fölling en
Noruega 12. La enfermedad ha sido el paradigma de las
.”
enfermedades metabólicas hereditarias y es la primera que
permitió hallar la explicación bioquímica del retraso mental
¿QUE ES LA FENILCETONURIA ?
• La fenilcetonuria es un trastorno genético que provoca una
acumulación de fenilalanina (un aminoácido) en el cuerpo. La
fenilalanina es un componente de las proteínas que se
encuentra en muchos alimentos. La fenilcetonuria se produce
cuando el cuerpo no puede descomponer la fenilalanina
correctamente debido a la falta de una enzima llamada
fenilalanina hidroxilasa.
Causas de la fenilcetonuria
• La acumulación de
fenilalanina en la sangre es
perjudicial porque este
La fenilcetonuria (PKU) es causada por una aminoácido es tóxico para el
deficiencia enzimática crítica en el metabolismo sistema nervioso,
de un aminoácido esencial llamado fenilalanina. especialmente para el
El proceso normal del metabolismo de la cerebro en desarrollo
fenilalanina implica la conversión de este
aminoácido en otro aminoácido llamado tirosina,
que es fundamental para la síntesis de proteínas y
neurotransmisores en el cuerpo.
Consecuencias fisiológicos

• Daño neurologico
• Alteracion en la piel y Cabello
• Problemas musculares
• Retraso en el Desarrollo
• Trastorno en el comportamiento
Síntomas y efectos de la fenilcetonuria
Tratamiento de fenilcetonuria

• Una dieta de por vida con un consumo muy limitado de


alimentos con fenilalanina
• Tomar una fórmula para la fenilcetonuria (un
suplemento nutricional especial) de por vida para
asegurarse de obtener suficiente proteína esencial (sin
fenilalanina) y nutrientes que son fundamentales para el
crecimiento y la salud en general
• Medicamentos para ciertas personas con fenilcetonuria
These are three ideas

MERCURY VENUS MARS


It’s the closest planet to the Venus has a beautiful name Despite being red, Mars is
Sun and the smallest in the and is the second planet from actually a cold place. It’s full
Solar System the Sun of iron oxide dust
02
Types of chemical
reactions
You can enter a subtitle here if you
need it
You can use four columns if you want

MARS NEPTUNE
Mars is actually a very It’s the farthest planet
cold place from the Sun

JUPITER SATURN
It’s the biggest planet in Saturn is a gas giant and
the Solar System has several rings
Sometimes, reviewing concepts is a good
idea
MARS VENUS NEPTUNE
Mars is actually a very Venus has extremely Neptune is very far from
cold place high temperatures the Sun

MERCURY SATURN JUPITER


It’s the closest planet to Saturn is the only planet Jupiter is the biggest
the Sun with rings planet of them all
Awesome
words
Causas de la fenilcetonuria
01 02
ABOUT IT TYPES
You can describe the topic of You can describe the topic of
the section here the section here

04 05
BALANCING LAB
You can describe the topic of You can describe the topic of
the section here the section here
01
Chemical
reactions
You can enter a subtitle here if you
need it
A picture is worth a thousand words
A picture
always
reinforces the
concept
Images reveal large amounts of data, so
remember: use an image instead of a long
text. Your audience will appreciate it
4,498,300,000
Big numbers catch your audience’s attention
24h 37m 23s
is Jupiter's rotation period

333,000,000
Earths is the Sun’s mass

386,000 km
is the distance between Earth and the Moon
Let’s use some percentages

25% 50% 75%


MERCURY VENUS MARS
It’s the closest planet to the Venus has a beautiful name Despite being red, Mars is
Sun and the smallest in the and is the second planet actually a cold place. It’s full
Solar System from the Sun of iron oxide dust
Desktop
software
You can replace the image on the
screen with your own work. Just
right-click on it and select “Replace
image”
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APP
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OUR TEAM

Sofia Hill Kaliyah Harris


You can talk a bit about this You can talk a bit about this
person here person here
Nationality of the greats of chemistry
VENUS
It has a beautiful name,
but it’s terribly hot

MERCURY
Mercury is the closest
planet to the Sun

MARS
Despite being red,
Mars is a cold place
Chemistry timeline: Contributions

Mercury is the smallest Despite being red,


planet of them all mars is very cold

PRIESTLY DALTON
1774 1743 1803 1897
LAVOISIE
THOMSON
Rextremely
Venus has Jupiter is the biggest
high temperatures planet of them all
Infographics make your idea
understandable…
MARS VENUS
Mars is actually a Venus has extremely
very cold place high temperatures

MERCURY SATURN
It’s the closest Saturn is the only
planet to the Sun planet with rings
…and the same goes for tables

MERCURY 0.06 0.38 0.38

MARS 0.11 0.53 0.38

SATURN 95.2 9.4 1.16


Describing chemical reactions
Mercury is the closest planet to the Sun and the smallest one in the Solar
System—it’s only a bit larger than the Moon

REACTANTS PRODUCTS
Jupiter is a gas giant, it doesn’t have Despite being red, Mars is actually a
a solid surface. It is the biggest cold place. It’s full of iron oxide
planet of them all dust
Reaction profiles & enthalpy change

Reactants

Enthalpy
Potential energy

Mercury is the
smallest planet

Products = Hp-Hr

Reaction pathway

Follow the link in the graph to modify its data and then paste the new one here. For more info, click here
Balancing chemical reactions
Step 1
Mercury is the closest CH4 CI2 CCI4 HCI
planet to the Sun. It’s
very small

Step 2 CH4 4 CI2 CCI4 4 HCI


Despite being red, Mars
is actually a cold place

C-1 C-1
Step 3
Earth is the beautiful
H-4 H-1 H-4
planet where we all live
Cl-2 Cl-8 Cl-5 Cl-8
Types of chemical reactions
Synthesis

Decomposition

Single replacement

Double replacement
Lab: Rating chemical reactions I
Is mercury the smallest planet in the entire
Question Solar System?

Hypothesis Mercury is the closest planet to the Sun


and the smallest of them all

Materials Preparation
● Mercury ● Despite being red, Mars is actually
● Mars a cold place
● Neptune ● Neptune is the farthest planet from
● Saturn the Sun
● Jupiter ● Jupiter is the biggest planet of them
● Venus all
Lab: Rating chemical reactions II
Data and observations:
Saturn is a gas giant and has several rings. It's composed mostly of
hydrogen and helium. It was named after the Roman god of wealth and
agriculture

Conclusion:
Despite being red, Mars is a surprisingly cold planet. Its color is due to
the presence of iron oxide dust clouds
Special symbols often used in chemical
equations
Mercury is the closest planet
SOLID (s) to the Sun
Jupiter is the biggest planet
LIQUID (l) of them all
Venus is the second planet
GAS (g) from the Sun
Neptune is the farthest
AQUEOUS (aq) planet from the Sun

Example: C H4 (g) + 2 O2 (g) C O2 (g) + 2 H2O(l)


Chemical reactions

Endothermic Exothermic Equations


Mercury is the Despite being red,
closest planet to the Mars is actually a
Sun and the cold place. It's full
smallest one in the of iron oxide dust,
which gives the
Chemical Words and
Solar System—it’s
only a bit larger planet its reddish symbol signs
than the Moon cast
Mars is a cold Mercury is a
place small planet
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