Documentos de Académico
Documentos de Profesional
Documentos de Cultura
IDEA DE INVESTIGACIÓN
Introducción y Ejemplo:
Lino, un ilustre joven médico, estudiante de una maestría en ciencias de la salud, se interesó
dedicarse a asesorar a padres y madres de familia, así como a rectores de unidades educativas
Así, su idea de investigación vinculada a lo que quiere hacer cuando egrese fue: Evaluar el valor
nutricional de los alimentos que se expenden en bares de unidades educativas y asociarlo al IMC
de los niños que consumen dichos alimentos. Además, se cuestionó respecto de la relación que
Lino, primero, revisó la existencia de modelos de análisis e instrumentos validades para evaluar
Se Requiere. -
1. Complete la idea de Lino respecto de los modelos de análisis e instrumentos validades para
Existen diversos modelos de análisis en los que la investigación de Lino puede hallar su eje
de Masa Corporal, todo esto con el fin de poder detectar la existencia o no de un déficit nutricional
3
grave que en muchas situaciones puede desencadenar en enfermedades graves como el escorbuto
La metodología utilizada para la determinación del IMC consiste en la aplicación de una fórmula
sencilla donde se hace uso de dos datos importantes que son la talla y peso:
𝑃𝑒𝑠𝑜 (𝐾𝑔)
𝐼𝑀𝐶 =
𝑇𝑎𝑙𝑙𝑎2 (𝑚)
en relación con otros niños o adolescentes del mismo sexo y edad. (CDC, 2021) Las categorías del
nivel de peso del IMC por edad y sus percentiles se detallan a continuación:
Tabla 1
Categorías del nivel de peso del IMC por edad y sus percentiles
Para tener una idea más clara de esto se detalla el siguiente ejemplo:
Figura 1
2. Piense en una idea de investigación que se relacione con la idea de Lino y coméntela con su
grupo de trabajo. Elaboren y escriban, en conjunto, una idea de trabajo que complemente a la
de Lino.
5
comunicación y redes sociales, así como también el aumento del uso de tecnología en niños y
la salud y estado físico de niños y adolescentes desde tempranas edades son factores de riesgo
debido al gran impacto que estos representan sobre la salud de los mismos.
3. Piense y escriba una idea de investigación propia enfocada en sus intereses personales,
incluido espacios.
Es importante intervenir efectivamente en la nutrición de los niños durante los primeros años de
vida, pues es en su infancia donde la ingesta de energía es más alta, así como también es mayor la
capacidad de responder a una buena nutrición por parte de los niños. Al igual que en muchos
países, en Ecuador también muchos niños están expuestos a factores de riesgo que incrementan la
crecimiento y desarrollo, en el mundo son más de trecientos millones de niños menores de 5 años
afectan de manera significativa el bienestar humano en especial para aquellas familias que forman
malas prácticas alimenticias debido a la falta de acceso productos básicos que les brinden el aporte
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actividades diarias, muchos de estos niños se ven privados de por lo menos ingerir las 3 comidas
diarias debido a su situación económica o en un gran número de veces debido al trabajo infantil al
que se ven sometidos como una alternativa de ayuda en la sostenibilidad económica de sus hogares.
Es por esta razón que nace mi idea de reconocer la existencia de mala nutrición en niños de etapa
en conjunto con la sociedad y padres de familia que nos faciliten la erradicación de futuros
problemas de salud y aprendizaje de los niños durante su desarrollo cognitivo en las instituciones
educativas.
canastas básicas alimenticias con el fin de disminuir la desnutrición infantil que pueda estar
presente.
Para realizar este estudio será necesario utilizar un modelo estadístico que nos permita determinar
utilización de medidas de IMC y los respectivos percentiles que estos representen de acuerdo a
caracteres incluidos espacios. Al final del resumen, exprese por escrito según su criterio,
seleccionado.
La desnutrición es un factor crítico de mortalidad y morbilidad en niños en todos los países del
mundo y se encuentra asociado con muertes de niños menores de 5 años de edad principalmente,
muchos países de bajos recursos económicos e incluso los de medianos recursos económicos tienen
problemas importantes con la desnutrición infantil como con el sobrepeso u obesidad que también
es denominada “la doble carga de la malnutrición”. Las principales formas de malnutrición son el
La principal causa de desnutrición primaria infantil en países con recursos económicos bajos es la
falta de suministro de alimentos adecuados debido a diferentes factores entre los que se encuentran
crónicas.
Un marcador de desnutrición crónica y que a menudo es el más frecuente entre los niños es el
retraso en el crecimiento, así como también existen otras características a tomar en cuenta como
son: la actividad física reducida, apatía mental, retraso psicomotor y retraso del desarrollo mental.
Criterio
Al ser la desnutrición infantil un tema comúnmente asociado a la falta de recursos económicos que
permitan a las familias adquirir por lo menos los alimentos básicos en una dieta saludable, este
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subdesarrollado donde prevalezca la pobreza, pues es esta brecha socioeconómica la que incide de
manera significativa en el crecimiento de los números de niños con desnutrición a edades muy
tempranas debido a la falta de acceso a un trabajo que provea a sus familias de los recursos
5. En un texto escrito, exprese una idea de investigación en otro campo de estudio lejano al que
usted ha escogido que guarde relación con experiencias vividas en la próxima semana. Exprese
BULLYNG
El acoso escolar o bullyng ha ido cobrando mayor fuerza con el pasar de los años y ha conllevado
a un sinnúmero de problemas psicológicos y sociales en las personas que sufren de este tipo de
abuso que muchas de las veces empieza desde etapas escolares muy tempranas y que terminan con
consecuencias sumamente negativas. El bullyng no solo afecta a quienes son acosados sino
también a quienes acosan y a quienes son testigos de lo ocurrido, tiene un gran impacto negativo
sobre la salud mental, incita el comienzo de uso de sustancias tóxicas e incluso a pensamientos y
actos suicidas.
Sería importante el saber por qué razón comienza el abuso escolar, cuáles son los factores que
determinan a una persona como acosador, a otra como víctima y a otra más como testigo, pues
soledad, cambios en los patrones de alimentación y de sueño, bajo desempeño escolar que en
Referencias
CDC. (15 de septiembre de 2021). Obtenido de Acerca del IMC para niños y adolescentes:
https://www.cdc.gov/healthyweight/spanish/assessing/bmi/childrens_bmi/acerca_indice_
masa_corporal_ninos_adolescentes.html#percentil-del-IMC
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ANEXO
ARTÍCULO CIENTÍFICO
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Contributor Disclosures
All topics are updated as new evidence becomes available and our peer review process is complete.
Literature review current through: Sep 2022. | This topic last updated: Aug 15, 2022.
INTRODUCTION
In this topic review, we use the term "malnutrition" in its traditional sense, referring to
undernutrition (wasting, stunting, or micronutrient deficiencies), although some authors
use the term more broadly to encompass overnutrition/obesity. Indeed, many low- and
middle-income countries have substantial problems with both undernutrition and
overweight/obesity, sometimes termed the "double burden of malnutrition" [2].
The major forms of malnutrition are marasmus (wasting) and kwashiorkor (edematous
malnutrition), with or without associated stunting. The clinical assessment of the child with
malnutrition includes distinguishing between these types, assessing their severity, and
identifying acute life-threatening complications, including sepsis and acute dehydration.
These children are at risk for micronutrient deficiencies, as detailed in a separate topic
review. (See "Micronutrient deficiencies associated with malnutrition in children".)
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EPIDEMIOLOGY
● Acute malnutrition – Approximately 31.8 million children (4.5 percent of all children
under five years of age worldwide) have moderate wasting (indicating moderate acute
malnutrition [MAM]) [3]. An additional 13.6 million children in this age group have
severe wasting (indicating severe acute malnutrition [SAM]) [4]. MAM and SAM are
primarily a problem in resource-limited regions and especially South Asia (including
Afghanistan, India, Pakistan, Bangladesh, and Nepal) and sub-Saharan Africa. They
are uncommon in North America, Australia, and other resource-rich regions.
CHRONIC MALNUTRITION
Stunting is a marker for chronic malnutrition and is often present in children with acute
malnutrition. Stunting is often accompanied by features of acute malnutrition, such as poor
weight gain and deficits in lean body mass and adipose tissue. Other features include
reduced physical activity, mental apathy, and retarded psychomotor and mental
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development [6-8].
ACUTE MALNUTRITION
Severe acute malnutrition (SAM) is associated with one of two classical syndromes:
marasmus (wasting syndrome) and kwashiorkor (edematous malnutrition), or a
combination of the two (marasmic kwashiorkor). Children with acute malnutrition appear
wasted (or show a decrease in mid-upper arm circumference [MUAC], weight-for-length,
and/or body mass index), whereas children with chronic malnutrition have stunted linear
growth and/or are underweight. Malnourished children may also suffer from numerous
associated complications, including dehydration, infection, and vitamin deficiencies. (See
'Evaluation for comorbid conditions' below and 'Specific nutrient deficiencies' below.)
Clinical subtypes — SAM can be divided into clinical subtypes based on the presence or
absence of edema. Malnutrition without edema is known as marasmus or wasting, and
malnutrition with edema is known as kwashiorkor (or edematous malnutrition).
Distinguishing physical features are listed in the table ( table 1). In the past, children with
kwashiorkor were previously thought to have worse outcomes compared with those with
marasmus, but more recent large studies demonstrate that children with kwashiorkor tend
to have better outcomes, perhaps due to the additional burden of higher rates of human
immunodeficiency virus (HIV) and diarrheal dehydration among those with marasmus
[11-13].
● Head that appears large relative to the body, with staring eyes
● Emaciated and weak appearance
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Edema is assessed by pressing down firmly on the third to fourth tarsal bones on the
dorsum of the foot for three to five seconds and then assessing for pitting edema for two
to three seconds [14].
Intermittent periods of adequate dietary intake restores hair color, occasionally resulting in
alternating loss of hair color interspersed between bands of normal pigmentation ("flag
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sign") ( picture 3). Stunting (reduced height for age) is often superimposed on both
marasmus and kwashiorkor, reflecting not only inadequate caloric intake but also the
cumulative effects of chronic poverty, food insecurity, and infectious risks that these
children face.
Some children have features of both marasmus and kwashiorkor, sometimes known as
marasmic kwashiorkor.
● Lungs – Surprisingly, children treated for SAM do not experience negative effects with
regard to later lung function [18].
● Genitourinary system – Glomerular filtration rate is reduced, and the capacity of the
kidney to excrete sodium, excess acid, or a water load is greatly reduced. Urinary tract
infections are common [20].
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have more severe pancreatic insufficiency than those with severe wasting [21].
However, pancreatic enzyme replacement therapy does not improve weight gain [21].
The mucosa of the small intestine is atrophied, and production of digestive enzymes
and membrane nutrient transporters is reduced. Lactase deficiency is common,
leading to lactose malabsorption [22], and absorption of all nutrients is reduced.
Intestinal motility is reduced, and this can be worsened by potassium and magnesium
deficiencies, potentially leading to ileus. Environmental enteric dysfunction, also
known as malnutrition enteropathy, is associated with villous atrophy, mucosal
thinning, increased intestinal permeability, loss of tight junction proteins (leading to
loss of gut barrier function), lymphocytic infiltration, and gut dysbiosis [23-25].
Luminal bacterial overgrowth is common, and the diminished gut barrier function,
which normally limits translocation of bacteria and their toxins, can lead to
bacteremia and sepsis.
● Immune system – Immune dysfunction and infections are closely associated with
malnutrition and are probably both a cause and consequence of malnutrition [26,27].
Severely malnourished children are at extremely high risk for superimposed infections
[28]. Multiple immune functions are diminished in marasmus; the mechanisms
include alterations in gut barrier function, intestinal dysbiosis and mucosal immunity,
reduced production of proinflammatory cytokines by adipose tissue ("adipokines"),
and micronutrient deficiencies [29]. Lymph glands, tonsils, and the thymus are
atrophied. Thymus size is inversely proportional to the duration of malnutrition [30]
and improves with treatment of malnutrition [31]. Cell-mediated (T cell) immunity,
immunoglobulin A (IgA) levels in secretions, complement levels, and phagocytosis are
all diminished. Although the acute phase immune response is intact, the typical signs
of infection, such as leukocytosis and fever, are frequently absent [32]. Septic shock is
often associated with hypoglycemia and hypothermia (see 'Sepsis' below). Other
inflammatory mediators (including interleukin-6 and C-reactive protein) are increased,
particularly in kwashiorkor (edematous malnutrition) [32,33].
● Endocrine system – Insulin levels are reduced, and the child may be glucose
intolerant. Growth hormone levels are increased, but levels of its downstream
effector, insulin-like growth factor 1 (IGF-1), are reduced. Cortisol levels are usually
increased.
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● Cellular function – Sodium pump activity is reduced, and cell membranes are more
permeable than normal, resulting in an increase in intracellular sodium and a
decrease in intracellular potassium and magnesium. Protein synthesis is reduced.
● Skin and glands – The skin and subcutaneous fat are atrophied, which causes loose
skin folds. Many signs of dehydration are unreliable. As examples, the eyes may
appear sunken because of loss of subcutaneous fat in the orbit and the child may
have dryness of mouth and eyes as well as reduced sweat production because of
atrophied sweat, tear, and salivary glands. (See 'Distinguishing sepsis from
dehydration' below.)
Thus, neither protein deficiency nor hypoalbuminemia appear to be the primary cause
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CLINICAL ASSESSMENT
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Estimates of the severity and duration of nutritional deprivation provide guidelines for the
nutritional rehabilitation of the malnourished child [54].
Z-scores also may be determined using the following calculators, which are based on the
WHO child growth standards:
● For ages 0 to 23 months – Boys (calculator 1); girls (calculator 2). These calculators
return Z-scores and percentiles for weight-for-length and length-for-age, which can
also be obtained from these WHO charts ( figure 2A-D).
● For ages 24 to 59 months – Boys (calculator 3); girls (calculator 4). These calculators
return Z-scores and percentiles for weight-for-height and height-for-age, which can
also be obtained from these WHO charts ( figure 3A-D)
Advantages of the MUAC compared with weight-for-length Z-scores (WLZ) are that it is a
better predictor of mortality, is easier to perform, and is not as affected by dehydration
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[55]. On the other hand, WLZ may detect another 40 percent of children with severe acute
malnutrition (SAM) who have normal MUAC values and WLZ scores are better correlated
with a number of biochemical indices of malnutrition associated with clinical morbidity [58].
Thus, the combination of both MUAC and WLZ is optimal for sensitivity and identifying
children at greatest risk [58,59].
These definitions of SAM are recommended by the WHO as criteria for identifying patients
who require urgent treatment [60]. The type of treatment program (outpatient or inpatient)
depends on the patient's overall clinical status, appetite, and comorbid disease. (See
"Management of complicated severe acute malnutrition in children in resource-limited
countries", section on 'Classification'.)
Infants <6 months — For infants younger than six months of age, there is no gold
standard for assessing the severity of malnutrition [62]. Both the weight-for-length Z-score
and MUAC have advantages and disadvantages in this population [55,63]. The most
common approach in this age group is to define severe malnutrition using the same weight
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and height criteria used for older infants and children (weight-for-length Z-score <–3 or the
presence of bilateral pitting edema) [60].
Three studies now confirm that MUAC <110 mm is highly associated with mortality in this
age group [64-66]. One of these studies showed that MUAC and weight-for-age Z-score <-3
are better predictors of mortality than weight-for-length Z-score [66].
Children 5 years and older — For children over five years of age and adolescents, the
WHO recommends the use of body mass index-for-age Z-scores to screen for malnutrition.
Alternatively, MUAC-for-age Z-score charts for children between 5 and 19 years have been
developed. In these charts, when cutoffs of -2 for moderate malnutrition and -3 for severe
malnutrition are used, they have been shown to correlate with mortality in Africa [67].
Hence, MUAC-for-age Z-scores may be an alternative method to screen for malnutrition in
children 5 to 19 years of age.
The World Health Organization (WHO) has suggested criteria for management of severe
malnutrition in various settings [60]. These guidelines enumerate criteria for admission and
discharge from an inpatient nutrition rehabilitation program for children 6 through 59
months ( algorithm 1B) or infants younger than six months ( algorithm 1A). They also
enumerate criteria for discharge from outpatient monitoring of a child who has recovered
from severe malnutrition. Hospital admission is indicated for children who have acute
complications, fail an appetite test, or have untreated HIV or tuberculosis or when other
considerations preclude safe and effective outpatient management. Note that the appetite
test is not a good predictor of treatment outcomes and thus should not be used as the sole
determinant of suitability for outpatient management [68]. (See "Management of
uncomplicated severe acute malnutrition in children in resource-limited countries", section
on 'Indications for inpatient care'.)
The parameter(s) used to monitor for recovery from malnutrition should be based on those
used to make the diagnosis of severe malnutrition. Thus, children with a low mid-upper
arm circumference (MUAC) should be monitored for gains in MUAC and children with low
weight-for-length Z-score should be monitored for gains in weight [69].
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A summary of the history and physical examination that should be used in the assessment
of a malnourished child is presented in the tables ( table 3A-B). Details of the assessment
are discussed in the sections below.
When clear distinguishing features are not present, it is often necessary to treat the child
for both dehydration and septic shock. The World Health Organization (WHO) recommends
antibiotic treatment for children with severe malnutrition, but the choice and course
depends on whether there is clinical evidence of infection. (See "Management of
complicated severe acute malnutrition in children in resource-limited countries", section on
'Infection'.)
• Weak or absent radial pulse – This is a sign of shock from either severe
dehydration or sepsis. As hypovolemia develops, the pulse rate increases and the
pulse becomes weaker. If the pulse in the carotid, femoral, or brachial artery is
weak, the child is at risk of dying and must be treated urgently.
• Cold hands and feet – This is a sign of both severe dehydration and septic shock. It
should be assessed with the back of the hand.
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• Thirst – Drinking eagerly is a reliable sign of mild dehydration. In infants, this may
be expressed as restlessness. Thirst is not a symptom of septic shock [70].
• Sunken eyes – This is a helpful sign of dehydration but only if the onset is recent,
according to the parent or caregiver [70].
• Features of incipient septic shock – The child is usually limp, apathetic, and
profoundly anorexic but is neither thirsty nor restless [70,71].
• Features of established septic shock – The superficial veins, such as the external
jugular and scalp veins, are dilated rather than constricted. The veins in the lungs
also may become engorged, making the lungs stiffer than normal. For this reason,
the child may groan, grunt, have a shallow cough, and appear to have difficulty
breathing. As shock worsens, kidney, liver, intestinal, or cardiac failure may occur.
There may be vomiting of blood mixed with stomach contents ("coffee-ground"
vomit), blood in the stool, and abdominal distension with "abdominal splash";
intestinal fluid may be visible on radiograph. When a child reaches this stage,
survival is unlikely [70,71].
Diarrhea and dehydration — Diarrhea is a serious and often fatal event in children with
severe malnutrition. Its presence is also a strong predictor of mortality among children with
complicated severe acute malnutrition (SAM) [72]. Although treatment and prevention of
dehydration are essential, care of these children must also focus on careful management of
their malnutrition and treatment of other infections [70,71].
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The consistency and volume of the stools are the most important characteristics for
distinguishing diarrhea from normal stool patterns. Diarrheal stools are watery or loose.
Frequent passing of formed stools is not diarrhea. Babies fed only breast milk often pass
loose, "pasty" stools; this also is not diarrhea [73,74]. Starved infants pass frequent, small-
volume (less than 10 grams), green liquid stools. These "starvation stools" can be
differentiated from diarrhea by inspection [71].
When a child presents with malnutrition and diarrhea, the type of diarrhea helps to predict
potential complications [71,75]:
● Acute watery diarrhea, which lasts several hours or days. The main danger is
dehydration; acute malnutrition occurs if feeding is not continued.
● Acute bloody diarrhea, which is also called dysentery. The main dangers are intestinal
damage, sepsis, and acute malnutrition; dehydration may also occur.
● Persistent diarrhea that lasts 14 days or longer. The main danger is chronic
malnutrition and serious nonintestinal infection; dehydration and vitamin deficiencies
may also occur.
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blood flow to vital organs [70,71]. (See 'Distinguishing sepsis from dehydration' above.)
Management of dehydration in a child with more than mild malnutrition should take place
in a hospital. Rehydration and refeeding are discussed in a separate topic review. (See
"Management of complicated severe acute malnutrition in children in resource-limited
countries", section on 'Dehydration'.)
Children with diarrhea who do not meet criteria for malnutrition should be evaluated for
dehydration using standard clinical signs and symptoms. Signs of early (mild) dehydration
include thirst, decreased skin turgor, dry mucus membranes, sunken eyes, and absence of
tears when crying. Signs of severe dehydration include altered consciousness, lack of urine
output, weak pulse, and poor perfusion ( table 5) [70,71]. (See "Clinical assessment and
diagnosis of hypovolemia (dehydration) in children".)
Other infections — In addition to assessing hydration, the child should be evaluated for
evidence of infection by assessing for fever, bloody stools, and respiratory distress. Fever
may be caused by severe dehydration or by a nonintestinal infection, such as malaria or
pneumonia [71]. However, the absence of fever does not exclude the possibility of infection,
because the acute phase response is attenuated in malnutrition. (See 'Pathophysiology'
above.)
Shigella and Campylobacter infections often present with bloody diarrhea, and both should
be treated in malnourished children [71]. Empiric therapy generally should be directed
against Shigella, based on the known sensitivities of local strains. (See "Persistent diarrhea
in children in resource-limited countries", section on 'Antimicrobials'.)
Children with respiratory distress should be evaluated with a chest radiograph if available,
but the radiographic signs of pneumonia may be less prominent in malnourished children
than in well-nourished children [70]. Children with presumed or established pneumonia
should be treated with antibiotics. (See "Management of complicated severe acute
malnutrition in children in resource-limited countries" and "Management of complicated
severe acute malnutrition in children in resource-limited countries", section on 'Infection'.)
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The initial evaluation of a malnourished child should assess for the following stigmata of
specific micronutrient deficiencies ( table 6 and table 7). When present, these require
specific treatment in addition to usual nutritional rehabilitation:
Essential nutrient deficiencies are sometimes grouped by those that interfere with growth
(type 2) or those that do not (type 1). Isolated deficiencies of vitamins A and D, thiamine,
folate, and iron are characterized by biochemical abnormalities or specific clinical
symptoms without anthropometric changes, a pattern that has been termed a "type 1"
nutrient deficiency ( table 7) [74]. Deficiencies of other nutrients, including protein,
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potassium, sodium, phosphorus, sulfur, zinc, and magnesium tend to cause reduced
growth rate without specific signs or diagnostic biochemical changes; this pattern is
sometimes termed a "type 2" nutrient deficiency. Affected children frequently have
persistent diarrhea and anorexia and usually are deficient in multiple nutrients. The
diagnosis of this type of deficiency is made by a growth response to a complete diet that
includes sufficient quantities of these nutrients [74]. Zinc deficiency can be considered both
type 1 and type 2 deficiency because it is also associated with some specific signs and
symptoms (eg, acral dermatitis, hypogeusia) and appears to increase risk for diarrhea
through unclear mechanisms.
Links to society and government-sponsored guidelines from selected countries and regions
around the world are provided separately. (See "Society guideline links: Pediatric
malnutrition".)
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caused by inadequate intake of all nutrients but especially dietary energy sources
(total calories). Affected children usually have some degree of stunting (suggesting
chronic malnutrition), as well as wasting. (See 'Marasmus' above.)
Children with either type of malnutrition are at risk for secondary infections and for
fluid overload. (See 'Pathophysiology' above.)
● Clinical assessment – A summary of the history and physical examination that should
be used in the assessment of a malnourished child is presented in the tables
( table 3A-B).
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dehydration' above.)
ACKNOWLEDGMENT
The UpToDate editorial staff acknowledges Buford L Nichols, MD, who contributed to
earlier versions of this topic review.
REFERENCES
1. UNICEF. Malnutrition: May 2022. Available at: https://data.unicef.org/topic/nutrition/m
alnutrition (Accessed on July 12, 2022).
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3. World Health Organization. UNICEF/WHO/The World Bank Group joint child malnutriti
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