Documentos de Académico
Documentos de Profesional
Documentos de Cultura
MEDIASTINO Y SISTEMA DE
CONDUCCIÓN.
Docentes:
Dr. Mario Castro Rachumí
Dra. Silvia Díaz Arroyo
Dr. Jorge Narváez Restelli
Walter Espino Saavedra
Médicos Anatomopatólogos
Endocardio
CORAZÓN
Miocardio
Epicardio
MUSCULO CARDIACO
Endocardio: constituido por un endotelio y un espacio subendocárdico formado por
tejido conectivo.
ENDOCARDIO
ENDOTELIO
ENDOCARDIO DE LA
AURICULA
ENDOCARDIO
ENDOTELIO
ENDOCARDIO DEL
VENTRICULO
Fibras elásticas en el endocardio
Miocardio y H&E
endocardio
E=endocardio
Masson's
trichrome.
Miocardio
Epicardio: formado por tejido conectivo recubierto por un mesotelio.
ad = adipose tissue
bv = blood vessel
nv = nerve
Myo = myocardium
ad = adipose tissue
bv = blood vessel
nv = nerve
Myo = myocardium
MUSCULO ESTRIADO CARDIACO MUSCULO ESTRIADO ESQUELETICO MUSCULO LISO
Corte
transversal:
1.-Endocardio
2.Miocardio
2
Corte transversal
Musculo cardiaco:
•Ramificaciones tridimensionales
de las células musculares
cardiacas.
NODO
SINUSAL
NODO
ATRIOVENTRICULAR
RAMA VENTRICULAR
HAZ DE IZQUIERDA
HIS
RAMA VENTRICULAR
DERECHA
FIBRAS DE
PURKINJE
•El nódulo sinusal está ubicado a la altura de la desembocadura de la
vena cava superior en la aurícula derecha , en el “surco terminal”
La flecha, en el
epicardio, indica el
corte transversal del
nódulo sinusal, de
contornos piriformes,
arteria nodal al
centro.
Van Gieson.
Nódulo sinusal
con arteria
nodal. H-E, 30x.
NODO
SINUSAL
Van Gieson.
Nódulo atrioventricular. Fibras delgadas, dispuestas a manera de
malla, en los espacios de ésta se ve el estroma. H-E, 80x.
Nódulo atrioventricular sobre el trígono fibroso (color rosa,rojo)
Van Gieson, 32x.
Seccción transversal
del haz de His.
PF:fibras de Purkinje
muestran su nucleo unico
pálido (N) con esta tinción.
Un delgado tejido
conectivo(CT) rodea las
fibras de Purkinje.
Purkinje fibres H&E/Elastin. 150x, 200x
P=Purkinje fibres
E=endocardial elastin
M=myocardium
Fibras de
purkinje
Fibras de
purkinje
Fibras
miocárdicas de
trabajo y fibras
de Purkinje.
Hematoxilina de
Heidenhein,
500x.
HEART (PURKINJE FIBERS)
Stained with
haematoxylin and eosin
1 - Purkinje fibers
2 - endocardium
3 - myocardium
FIBRAS
DE
PURKINJE
The conducting system. N:
nuclei, E: endocardium, NF:
Purkinje fibres course nerves
and M: myocardium (Ross and
Pawlina, 2011).
endothelium (En), subendocardial layer (SEn), Purkinje fibers (P)
FIBRAS DE PURKINJE
FIBRAS DE PURKINJE
N(P) - nuclei of Purkinje
fibers
P - Purkinje fibers (cross
section)
bv = blood vessel
c = capillary
car = regular cardiac fibres
ID = intercalated disks
n = nuclei of Purkinje cells
bv = blood vessel
CT = connective tissue
n = Purkinje cell nucleus
PERICARDIO
Myocardium (M), epicardium (Ep). The epicardium consists of loose connective tissue (CT) containing autonomic nerves (N) and variable amounts of fat (F). The epicardium is the visceral layer of the
pericardium and is covered by the simple mesothelium (Mes) that also lines the pericardial space. The mesothelial cells secrete a lubricant fluid that prevents friction as the beating heart contacts the
parietal pericardium on the other side of the pericardial cavity. X100. H&E.
Endo - endocard
P - Purkinje fibers (cross
section)
arrowheads - endothelial
cells
PERICARDIO
Parietal pericardium. (a) EVG stain of parietal pericardium displaying the serosal (mesothelial) layer and fibrous layers composed of collagen and elastic fibers. (b) H&E stain of parietal pericardium
displaying serosal (mesothelial) layer and collagen fibers (Courtesy of Dr. Shweta Gera and Dr. Pushpa Kancherla, Mt. Sinai St. Luke’s Pathology Department, New York, NY)
PERICARDIO
VÁLVULAS CARDIACAS
Válvula aórtica:
a. ventricular (v) rica en elastina
b. Esponjosa (s) (tejido conectivo laxo)
c. Fibrosa (f) (tejido conectivo denso)
•Las células endoteliales son señaladas por la flecha.
•Las dos flechas señalan el tejido elástico de la capa ventricular, mientras que en la capa fibrosa se ve en color amarillo la colágena,
con células interticiales distribuídas en forma difusa en su interior.
Heart valve H&E. 15x
M=myocardium
F=lamina fibrosa
S=fibro-elastic supporting layer
E=endothelium
The layers of the heart wall. End: endothelium, DCT: dense connective tissue, PF: Purkinje fibres,
CMF: cardiac muscle fibres and SMC: smooth muscle cells ( Ross and Pawlina, 2011 ).
The fibrous cardiac skeleton consists of dense irregular connective tissue, primarily in the endocardium (En), which anchors the valves and surrounds the two
atrioventricular canals, maintaining their proper shape. The micrograph shows a section through a cusp of an atrioventricular valve (arrow) and attached chordae
tendineae (CT). These structures are largely dense connective tissue (C) covered with a thin layer of endothelium. The collagen-rich connective tissue of the valves is
stained pale blue here and is continuous with the fibrous ring of connective tissue at the base of the valves, which fills the endocardium between the atrium (A) and
ventricle (V). The thick ventricular myocardium (M) is also shown. X20. Masson trichrome.
a) a cuspid valve; b) tissue layers within heart valves (Ross and Pawlina, 2011).
VÁLVULA MITRAL
Lymphatic vessels. Val: valve, DCT: dense irregular connective tissue, AT: adipose tissue, Ad: adipocyte, A:
arteriole, L: lymph material and V: venule (Ross and Pawlina, 2011).
REFERENCIAS BIBLIOGRAFICAS
1. GARTNER, LESLIE P. HIATT, JAMES L. (2006) ATLAS COLOR
DE HISTOLOGÍA EDITORIAL MËDICA PANAMERICANA
BUENOS AIRES 3ra. EDICIÓN.
2. GENESER, FINN (2015), HISTOLOGÍA: SOBRE BASES
MOLECULARES, 4TA EDICIÓN.EDITORIAL MÉDICA
PANAMERICANA, BUENOS AIRES
3. Scientific Foundations disponible en
http://medcell.med.yale.edu/image_gallery/blood.php
4. Blue Histology - Blood - School of Anatomy and Human
Biology - The University of Western Australia disponible en
https://www.lab.anhb.uwa.edu.au/mb140/CorePages/Blood/blood
.htm