Vacxin Thú y

BO NONG NGHIEP VA PHAT TRIEN NONG THON
TRUNG TAM KHUYEN NONG QUOC GIA

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PGS.TS. Pham Sy Lang

TS. Nguyen Ba Hien
TS. Phung Quoc Quang
VACXIN THU Y
VA HNG DAN S DUNG
HA NOI, 2012
LI GII THIEU

Trong nhng nam gan ay, chan nuoi gia suc, gia cam nc ta phat trien manh, vi
toc o tang trng bnh quan 6-8%/nam va gi vai tro rat quan trong trong nen san xuat
nong nghiep.
Theo so lieu thong ke, tnh en nam 2012, ca nc ta co 5,3 trieu con bo, 2,9 trieu
con trau, tren 28 trieu con ln, tren 300 trieu con gia cam va gan 1,3 trieu con de, cu....
Cung vi s phat trien manh cua chan nuoi, tnh hnh dch benh tren gia suc, gia cam
cung dien bien het sc phc tap, chang nhng gay ton that rat nang ne oi vi nen kinh
te ma con e doa en tnh mang cua con ngi. Viec ap dung cac bien phap an toan
sinh hoc trong chan nuoi mang tnh cap thiet. No bao am cho chan nuoi hieu qua, tao
ra nhng san pham chat lng, ve sinh, an toan ong thi bao ve moi trng trong lanh
va sc khoe cong ong.
Co nhieu bien phap chan nuoi an toan sinh hoc trong o tiem phong vacxin cho an
vat nuoi la mot trong nhng bien phap quan trong va mang lai hieu qua cao. Tuy nhien,
cho en nay cac ch dan cung nh cac quy nh ve van e nay cha c tap hp thong
nhat va pho bien rong rai.
Xuat phat t thc te tren, chung toi cho bien soan va phat hanh cuon "Vacxin thu y
va hng dan s dung". Sach gom 4 chng:
Chng 1: nh ngha va phan loai vacxin
Chng 2: Nguyen tac va cac quy nh s dung vacxin
Chng 3: Lch s dung vacxin phong benh cho gia suc, gia cam
Chng 4: Mot so vacxin a c s dung co hieu qua Viet Nam
Ngoai ra, cuon sach con cap nhat cac van ban quan ly nha nc, quy nh phong
chong mot so benh nguy hiem vat nuoi.
Cuon sach do cac chuyen gia giau kinh nghiem bien soan va c trnh bay n
gian, de hieu, de van dung. Chung toi hy vong cuon sach se rat bo ch oi vi cac can
bo nghien cu, can bo giang day, ac biet la oi vi cac can bo thu y, khuyen nong t
trung ng en c s va cac chu trang trai, gia trai chan nuoi gia suc, gia cam.
Chung toi tran trong gii thieu cuon sach va mong nhan c nhng y kien ong gop
cua Quy ban oc.
TRUNG TAM KHUYEN NONG QUOC GIA
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MUC LUC
Chng 1: NH NGHA VA PHAN LOAI VACXIN

I. nh ngha vacxin .............................................................................................5
II. Phan loai vacxin thu y .....................................................................................6
Chng 2: NGUYEN TAC VA CAC QUY NH S DUNG VACXIN
THU Y..................................................................................................................9
I. Nguyen tac s dung vacxin thu y....................................................................9
1. Xac nh pham vi hp ly tiem vacxin va la chon vacxin.................................9
2. Tiem phong vacxin ung oi tng.................................................................10
3. Tiem ung thi gian, ung quy cach, at ty le cao.........................................10
3.1. Tiem ung thi gian...................................................................................10
3.2. Tiem ung lieu va ung ng...................................................................11
3.3. Ky thuat s dung vacxin.............................................................................11
4. Phoi hp cac loai vacxin..................................................................................12
5. Mot so ieu chu y khi s dung va bao quan vacxin.........................................12
6. Cac phan ng khong mong muon khi tiem phong vacxin va cach khac phuc........13
6.1. Nhng tac dung phu khi tiem phong vacxin................................................13
6.2. Nhng tai bien khi s dung vacxin.............................................................14
II. Quy nh ve viec tiem phong vacxin ba t buo c cho gia su c, gia ca m
Vie t Nam..................................................................................................15
1. Pham vi, oi tng s dung..............................................................................15
2. Giai thch thuat ng.............................................................................................15
3. Cac benh phai tiem phong, ty le tiem phong..................................................16
4. Tiem phong oi vi tng benh ........................................................................16
4.1. Benh l mom long mong............................................................................16
4.2. Benh dch ta ln.............................................................................................16
4.3. Benh nhiet than..........................................................................................17
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4.4. Benh tu huyet trung .........................................................................................17
4.5. Benh ong dau ln....................................................................................17
4.6. Benh dai....................................................................................................18
4.7. Benh Newcastle.........................................................................................18
4.8. Benh dch ta vt.........................................................................................18
4.9. Benh cum gia cam.....................................................................................18
5. Trach nhiem thc hien ...................................................................................18
Chng 3: LCH S DU N G VACXIN PHO N G BE N H CHO GIA SU C ,
GIA CA M .........................................................................................................19
I. Mot so quy nh chung ve lch tiem phong .....................................................19
II. Lch tiem phong cu the oi vi cac oi tng vat nuoi .................................20
1. Lch s dung vacxin phong benh cho trau, bo.................................................20
2. Lch s dung vacxin phong benh cho ln........................................................21
3. Lch s dung vacxin phong benh cho ga.........................................................23
4. Lch s dung vacxin phong benh cho vt, ngan...............................................24
5. Lch s dung vacxin phong benh cho cho, meo..............................................24
Chng 4: MO T SO VACXIN A C S DU N G CO HIE U QUA
VIE T NAM .......................................................................................................25
I. Vacxin dung cho trau bo..................................................................................25
II. Vacxin dung cho ln.......................................................................................35
III. Vacxin dung cho gia cam..............................................................................70
IV. Vacxin dung cho gia suc khac......................................................................100
V. Vacxin phong benh cho tom, ca va vacxin ky sinh trung ............................102
PHU LUC.........................................................................................................104
TAI LIEU THAM KHAO CHNH..................................................................149
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Chng 1
NH NGHA VA PHAN LOAI VACXIN
I. NH NGHA
Vacxin la mot che pham sinh hoc trong o cha chnh mam benh hoac khang nguyen
cua mam benh gay ra mot benh truyen nhiem nao o can phai phong nga ma neu la mam
benh th phai c giet hoac lam nhc oc bi cac yeu to vat ly, hoa hoc hoac sinh vat
hoc. Khi s dung cho ong vat, vacxin tao ra mot ap ng mien dch chu ong chong lai s
xam nhiem cua mam benh tng ng.
Mam benh c goi la khang nguyen co the bao gom: virus, vi khuan, n bao, mot
phan khang nguyen cua mam benh.
ap ng mien dch tao ra chat mien dch trong c the ong vat sau khi s dung vacxin
c goi la khang the.
1. Nguyen ly hoat ong
Vacxin tao ra trong c the ong vat song mot ap ng mien dch. He thong mien dch
cua c the hoat ong sinh ra khang the dch the ac hieu hoac khang the te bao chong lai
khang nguyen la mam benh tng ng khi xam nhap vao c the ong vat.
2. ac tnh c ban cua vacxin
Vacxin co 4 ac tnh sau:
- Tnh mien dch:
La kha nang gay ra ap ng mien dch dch the hoac te bao hoac ca hai. Tnh sinh mien
dch phu thuoc vao khang nguyen va c the nhan khang nguyen (ngha la c a cua ong
vat nhan khang nguyen).
- Tnh khang nguyen hay tnh sinh khang nguyen:
Mot vacxin a vao c the phai co kha nang kch thch c the sinh ra khang the ac hieu
tng ng co trong vacxin.
- Tnh hieu lc:
Khang the sinh ra trong c the ong vat phai co kha nang tieu diet c mam benh
tng ng co trong vacxin khi s dung vacxin cho ong vat.
Th du: khi tiem vacxin tu huyet trung ln cho ln th c the ln phai tao ra c khang the
tieu diet c mam benh tu huyet trung tng ng nh mam benh c dung che tao vacxin.
- Tnh an toan:
Vacxin san xuat ra phai am bao c 3 yeu cau sau ay:
(i) Vo trung: khong c nhiem cac vi sinh vat khac.
(ii) Thuan khiet: khong c lan cac thanh phan khang nguyen khac co the gay ra cac
phan ng phu.
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(iii): Vo oc: sau khi san xuat, vacxin phai an toan, khong hoac t gay ra cac phan ng phu
khong mong muon cho ong vat. Lieu s dung phai thap hn rat nhieu so vi lieu gay oc.
II. PHAN LOAI VACXIN
Cac vacxin a va ang c s dung tiem phong cho ong vat c chia ra 4 loai sau:
1. Vacxin chet (vo hoat)
ay la loai vacxin kinh ien nhat, nguyen tac la lam chet mam benh (virus, vi khuan) nhng
van gi c tnh khang nguyen va kch thch sinh khang the ac hieu s dung cho ong vat.
Co 2 phng phap lam chet mam benh.
- Phng phap hoa hoc:
Dung hoa chat nh: formol, Ethylenimine V du: Vacxin ong dau ln vo hoat la
vacxin c che tao t vi khuan ong dau ln c nuoi cay tren moi trng va c lam
chet bang formol, co them vao chat bo tr la keo phen nen con c goi la vacxin ong
dau ln vo hoat keo phen.
- Phng phap vat ly:
Dung tia xa hoac sc nong e tieu diet mam benh. Th du: Vacxin phong benh sai sot
cho cho, ngi ta dung virus sai sot cho (carre) tang nhiet o len 600C lam chet virus va
che tao ra vacxin.
2. Vacxin song (vacxin nhc oc)
Vacxin song la vacxin c san xuat t cac chung virus hay vi khuan con song, gan nh
khong co tnh gay benh cho ong vat c tiem phong nhng co kha nang gay ap ng
mien dch cho ong vat. Mam benh nhc oc c nhan len trong c the ong vat va tiep
tuc tao ra s kch thch cua khang nguyen trong mot khoang thi gian.
Vacxin song bao gom: vacxin nguyen oc, vacxin vo oc va vacxin nhc oc.
- Vacxin nguyen oc:
Dung chung vacxin nguyen oc (gi nguyen oc lc t loai ong vat khac giong, khac
loai). V du: vacxin phong benh au cho ngi che tao t virus au bo cng oc.
- Vacxin vo oc (vacxin nhc oc t nhien):
c san xuat t nhng chung vi sinh vat vo oc phan lap trong t nhien. V du: ngi
ta a phan lap c mot so chung virus Niucatxn co trong an ga nuoi oc lc rat yeu
khong gay ra benh Niucatxn nhng khi xam nhap vao c the ga van tao ra mien dch ap
ng chong lai c chung virus Niucatxn cng oc. Cac chung virus nay c dung san
xuat vacxin nhc oc phong benh Niucatxn hien nay, trong o co chung virus Niucatxn
nguyen oc c phan lap t Hungary va dung e san xuat vacxin Lasota phong benh cho ga.
- Vacxin nhc oc:
La vacxin c san xuat t chung virus, vi khuan gay benh a c giam oc bang mot
trong cac phng phap: sinh vat hoc, hoa hoc va vat ly khong con kha nang gay benh
cho ong vat nhng s dung cho ong vat van tao c ap ng mien dch, diet c mam
benh co oc lc tng ng khi xam nhap vao ong vat.
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Mot so vacxin nhc oc a va ang c s dung:
- Vacxin nhiet than dung cho trau bo c giam oc bang nhiet: ngi ta nuoi cay vi
khuan nhiet than nhiet o 42,50 - 430C t 15 - 20 ngay; vi khuan mat kha nang hnh thanh
giap mo, oc lc giam, c s dung lam giong goc che tao vacxin.
- Vacxin BCG dung tiem phong benh lao c giam oc bang yeu to hoa hoc: ngi ta
phan lap, nuoi cay vi khuan lao bo trong moi trng trong 13 nam, sau 230 lan cay truyen,
vi khuan khong con oc, c san xuat vacxin BCG phong benh lao cho bo va cho ngi.
- Vacxin dch ta ln nhc oc chung C c giam oc bang phng phap sinh vat hoc:
virus cng oc dch ta ln c tiem truyen lien tuc 155 i qua tho, tr thanh chung virus
c dung ngay nay.
- Vacxin dch ta vt nhc oc: c giam oc bang cach dung chung virus dch ta vt
cng oc, cay truyen 41 - 46 i qua phoi ga, khong con oc lc gay benh cho vt, c
san xuat lam vacxin phong benh dch ta vt.
Bang so sanh u nhc iem cua vacxin song va vacxin chet
3. Vacxin di n v
Vacxin di n v la vacxin khong san xuat t nguyen con virus hay nguyen con vi
khuan ma c san xuat t khang nguyen tinh khiet phan lap t con vi khuan hay con virus.
- V du 1: Vacxin chong benh uon van cho ngi va ong vat: ngi ta nuoi cay vi khuan
trong moi trng, chiet tach oc to, giam oc bang yeu to hoa hoc hoac vat ly theo nguyen
ly vacxin chet. Cac oc to cua vi khuan uon van (clostridium tetani mat hoat tnh gay benh
c goi la giai oc to (anatoxin) va c dung lam vacxin.
- V du 2: Phay khuan ta gay benh nh noi oc to (enterotoxin), c goi la oc to di
n v A rat oc va 5 di n v c goi la B. Tuy khong oc, nhng 5 di n v B lai
co kha nang sinh khang the khi tiem vao c the bao ve c the chong c phay khuan ta
nen ngi ta nuoi cay vi khuan, tach di n v B dung lam vacxin phong benh ta.
Vacxin di n v co mc o thuan khiet va tinh khiet cao hn vacxin che tao t nguyen
con virus hoac vi khuan nen tnh man cam, tnh sinh khang the va tnh ac hieu eu cao.
4. Vacxin the he mi san xuat bang cong nghe gen
1. Khai niem
Vacxin the he mi la thanh pham cua mot quy trnh co s can thiep, s dung cac ky
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nang thao tac cua cong nghe gen va ng dung cac thanh tu nghien cu ve cong nghe sinh
hoc va sinh hoc phan t. Goi la vacxin the he mi e phan biet vi cac loai vacxin a c
nghien cu san xuat bang cac phng phap truyen thong.
2. Nguyen ly
Trong mot loai vacxin, yeu to quyet nh tnh mien dch chnh la thanh phan protein ac
biet tren be mat cua vi sinh vat (virus, vi khuan, n bao) gay benh. Thanh phan protein
nay c goi la khang nguyen va do mot gen hay mot so gen co trong he gen cua vi sinh
vat gay benh quyet nh tong hp nen. Nhng gen chu trach nhiem ve viec tong hp (hay
san xuat) protein khang nguyen c goi la gen khang nguyen.
Neu tach gen khang nguyen khoi vat lieu di truyen cua vi sinh vat roi ghep vi mot he
thong bam dnh trung gian (plasmic vector) thch ng nao o th gen khang nguyen nay van
hoat ong nh khi ton tai trong he gen cua vi sinh vat chu va phan t protein khang nguyen
c tong hp ra van co the co chc nang nh cu, ngha la co tnh sinh mien dch. Che
pham protein khang nguyen c tao ra nh the c goi la vacxin tai to hp hay vacxin
the he mi - vacxin cong nghe gen.
3. Phan loai vacxin the he mi:
Can c vao nguon khang nguyen nhan len c hay khong nhan len c trong c the
ong vat, ngi ta chia vacxin the he mi lam 2 loai nh sau:
a). Vacxin co khang nguyen song c nhan len.
Vacxin nay chia 2 thanh phan chnh la:
- oan ADN cho khang nguyen chnh c tach ra t vi sinh vat gay benh.
- He gen cua vector (trung gian) dan truyen
Hien nay cac vector dan truyen c chon la nhng vi sinh vat (virus, vi khuan, nam
men) thong dung co the nhan len c nhieu loai ong vat va a c giam oc hoac
vo oc bang ky thuat gen.
Th du 1: Vi khuan thng han (Salmonella Typhinurium) khong oc c chon lam
vector dan truyen e san xuat cac vacxin the he mi (vacxin cong nghe gen) nh: vacxin
cum, vacxin sot xuat huyet, vacxin lien cau khuan, ky sinh trung sot ret. Ngi ta cung
dung virus au bo lam vector dan truyen e san xuat: vacxin Niucatxn vi gen ma hoa
khang nguyen F, vacxin cum vi gen ma hoa khang nguyen H va N
Th du 2: Vacxin axit nucleic (vacxin ADN):
Loai vacxin nay c coi la vacxin co trien vong ln, nh: vacxin ADN cha gen H va
N chong cum.
Th du 3: Vacxin xoa gen oc: la vacxin cha yeu to gay benh c lam nhc oc bang
ky thuat gen cat bo gen oc. e tao ra giong goc san xuat vacxin cum gia cam, hien tai Bo y
te va Vien Khoa hoc Cong nghe Viet Nam a nhap ngoai chung virus NiBRG - 14 t Vien
tieu chuan va kiem nghiem sinh pham Quoc gia (Vng Quoc Anh). Chung NiBRG - 14 c
tao ra bang ky thuat di truyen thong qua viec ghep 6 gen cua chung PR8/34 (H1N1) vi 2 gen
cua chung virus A/Vietnam/1194/2004 (H5N1). Rieng gen H5 b loai 4 axit amin vung oc.
Chung virus nay co the nuoi cay tren phoi ga.
Vacxin phong benh gia dai cung la mot vacxin nhc oc tao ra theo kieu tren.
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b). Vacxin co nguon goc khang nguyen khong nhan len
Loai vacxin nay c san xuat bang cach tach gen khang nguyen gay benh, ghep vao
he gen cua mot loai vi sinh vat lam vector dan truyen (virus, vi khuan, nam men), nuoi cay
vi khuan tai to hp nay trong moi trng thch ng nh he thong thiet b len men ln, lng
protein se c san xuat ra nhieu, sau o chiet tach protein khang nguyen e lam vacxin.
Bang phng phap nay, ngi ta a che tao c vacxin phong dai Rabisin tao c
mien dch nhanh, on nh va thi gian ton tai cua khang the co the keo dai c 1 - 2 nam
khi s dung vacxin tiem phong dai cho cho.
Chng 2
NGUYEN TAC
VA CAC QUY NH S DUNG VACXIN THU Y
I. NGUYEN TAC S DUNG VACXIN THU Y

e co c hieu qua nh mong muon sau khi tiem phong vacxin th viec s dung vacxin
ung nguyen tac luon la ieu kien tien quyet. S dung vacxin sai nguyen tac khong nhng
khong mang lai hieu qua phong benh ma con dan en nhieu nguy c khac nh lam giam
kha nang e khang cua vat nuoi, tham ch gay ra nhng tai bien ang tiec. V vay, trong
qua trnh s dung vacxin can tuan thu cac nguyen tac sau ay:
1. Xac nh pham vi hp ly tiem vacxin va la chon vacxin
Viec xac nh chnh xac va hp ly pham vi tiem phong cua vacxin la vo cung quan trong
va can thiet, no am bao tnh tiet kiem trong s dung vacxin, ong thi lai ap ng c
yeu cau phong benh. e lam c ieu nay th cong tac ieu tra ve dch te hoc can c
chu trong. Thong qua cac thong tin ve dch te hoc va ban o dch te hoc cac nha hoach nh
ke hoach tiem phong co the xac nh mot cach chnh xac cac typ vi khuan, virus a tng
gay benh trong khu vc nh tiem la g, pham vi dch xay ra mc o rong hay hep, lan
cuoi cung dch xay ra tai a phng o la khi nao... t o a ra ke hoach nhap chung loai
va so lng vacxin hp ly phuc vu cho cong tac tiem phong tai a phng. V du: trong
cong tac phong benh l mom long mong Viet Nam chung ta ch nhap vacxin cha cac typ
O, A va Asia 1 trong khi virus l mom long mong co tat ca 7 typ.
Can phai tiem phong cac o dch cu, nhng vung hang nam co dch e doa, nhng vung
hai ben ng giao thong trong yeu, quanh cac ch, x nghiep che bien thu san, vung bien
gii... Khi co dch xay ra phai tiem chong dch trong o dch va cac vung xung quanh (vung
b dch uy hiep). Ngoai khu vc b uy hiep la vung an toan, mam benh kho co the lay lan
trong thi gian trc mat. Ca ba vung eu phai tiem phong vacxin cho gia suc con khoe
e tao ngay mot vanh ai an toan dch, ngan chan dch lay lan. oi vi nhng con nghi lay
trong o dch ngoai viec nhanh chong cach ly e theo doi co the tiem huyet thanh cung mot
luc vi vacxin e tao mien dch nhanh chong nhng phai tiem hai ni khac nhau va ch
ng dung vi vacxin chet. oi vi gia suc khac loai nhng co thu cam vi cung benh th
cung can c tiem vacxin.
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e ap ng c yeu cau phong benh th tiem phong can at ty le cang cao cang tot, noi
chung phai at ty le toi thieu 80%, cac vung b uy hiep phai at ty le 90 - 95%.
2. Tiem phong vacxin ung oi tng
Vacxin la thuoc phong benh cho ong vat khoe, cha mac benh. Neu trong c the ong
vat a mang san mam benh nhng cha phat ra th sau khi c tiem khang nguyen cung
loai vi mam benh co trong c the th benh phat ra sm hn, nang hn. Trng hp ngoai
le co the dung vacxin ma ong vat a nhiem mam benh. V du: s dung vacxin chong benh
dai cho ngi a b cho dai can, trng hp nay vacxin a tao ra khang the chong virus dai
trc khi virus dai len nao va tieu diet virus dai. benh dch ta ln viec tiem thang vacxin
vao o dch se co tac dung loai tr nhanh con mac benh nang, con nhng con mac benh nhe
hoac cha mac benh se tao c mien dch.
Bnh thng khong dung vacxin cho ong vat qua non va than trong vi ong vat co
thai. ong vat non, cac c quan am nhan chc nang mien dch bao ve c the cha hoan
chnh nen ap ng mien dch vi vacxin con yeu, khong nhng the ong vat non con co
mot lng khang the thu ong do me truyen cho, nhng khang the o co the ngan can
vacxin phat huy tac dung. Neu khong co dch e doa th ch nen dung vacxin cho suc vat t
2 - 7 tuan tuoi, dung vacxin cang muon cang tot. Khi co dch e doa buoc phai tiem phong
sm cho ong vat non nhng sau o can tiem bo sung.
ong vat mang thai, trang thai sinh ly co nhieu thay oi nen dung vacxin de gay ra
nhng phan ng manh va lam say thai. Mot ly do na khien chung ta khong nen s dung
vacxin trong thi ky gia suc cai mang thai la bao thai se nham lan khang nguyen a vao
la thanh phan cua ban than no do o khi sinh ra no se khong sinh c mien dch ngay ca
khi tiem phong bang loai vacxin o (hien tng dung nap mien dch). ac biet khong s
dung vacxin uong cho suc vat mang thai nhat la vacxin nhc oc.
3. Tiem phong ung thi gian, ung quy cach, at ty le cao
3. 1. Tiem ung thi gian
Phan ln cac benh truyen nhiem thng xay ra hoac phat trien ram ro vao mot thi gian
nhat nh trong nam nh benh tu huyet trung vat nuoi thng xay ra vao mua ma; dch
ta ln xay ra vao vu ong xuan; benh l mom long mong trau bo xay ra vao mua nong
tap trung vao thang 4 - 5. V vay, e phong mot benh truyen nhiem nao o can tiem phong
vacxin trc mua benh xay ra mot khoang thi gian u cho c the tao c mien dch
phong ve chac chan (thng la 2 - 3 tuan). V vay, mua tiem phong cua nc ta thng la
thang 3, thang 4 va thang 9, thang 10 hang nam.
Sau khi tiem phong vacxin, c the ch c bao ho oi vi benh a tiem phong trong
khoang thi gian nhat nh, khoang thi gian o phu thuoc vao tng loai vacxin (thng t
3 - 12 thang). Het thi gian o c the lai cam nhiem vi mam benh v vay can tiem nhac
lai kp thi e tao kha nang bao ho lien tuc. Ca biet co nhng loai vacxin se gay ra ap ng
mien dch suot i nh vacxin si ngi.
Hien tai, do y thc phong benh bang vacxin cua ngi chan nuoi cha cao cung vi tap
quan chan nuoi gia nh, quy mo chan nuoi nho le nen cong tac to chc tiem phong cho vat
nuoi con gap nhieu kho khan. Viet Nam, Phap lenh Thu y quy nh hang nam phai tiem
phong cho tat ca cac benh bat buoc phai tiem phong cho vat nuoi vao hai t, t mot la
thang 3 - 4, t hai la thang 9 - 10. Khong nhng the viec tiem phong bo sung cho gia suc
mi sinh, gia suc mi nhap la mot viec lam cung het sc quan trong.
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3. 2. Tiem ung lieu va ung ng
Tiem ung lieu: Phai tiem u lieu vacxin cho ong vat theo khuyen cao cua nha san xuat
ghi tren nhan mac hoac trong ban hng dan kem theo vacxin. Neu tiem qua lieu se tao c
che ap ng mien dch oi vi c the, hieu gia khang the ac hieu tao ra se thap, hoat ong
cua mien dch te bao se han che, lang ph vacxin, chi ph tiem phong tang. Ngc lai neu
tiem lieu thap hn lieu quy nh, se khong u lng khang nguyen kch thch c the ap ng
mien dch, hieu gia khang the ac hieu va hoat ong mien dch cua te bao eu thap, khong
tao c kha nang phong ve cho c the.
a vacxin ung ng quy nh: ng xam nhap thch hp cua tng loai mam benh
vao c the e gay benh lai rat khac nhau do o oi vi moi loai vacxin se co mot ng
a vao nhat nh. Cac ng a vacxin pho bien hien nay la tiem bap, tiem di da,
nho mat, mui, kh dung... Kha nang ap ng mien dch cua cac c quan co tham quyen
mien dch trong he thong mien dch cua c the oi vi vacxin a vao c the bang cac
ng khac nhau cung khac nhau. V vay, trong qua trnh nghien cu che tao vacxin cac
nha nghien cu a chu y la chon ng a toi u vao c the cho tng loai vacxin. Do
o khi s dung vacxin tiem phong cho ong vat nen a theo ng khuyen cao cua nha
san xuat.
ng thng tiem vacxin la tiem di da, nhat la vacxin co chat bo tr va tiem vi
lieu lng ln (vacxin keo phen, vacxin tu huyet trung, vacxin ong dau ln). Co loai phai
tiem ung di da e tranh phan ng (vacxin nhc oc nhiet than, nhc oc dch ta trau
bo, dch ta ln qua tho...) neu tiem lieu lng nho th co the tiem bap tht. Mot so vacxin
co the s dung cho uong, nho mat, nho mui,...
e phong benh ng ho hap nen la chon vacxin a qua mui hoac mat nh vacxin
Lasota nho mat, nho mui phong benh Newcastle cho ga. Phong benh ng ruot nen chon
vacxin cho qua ng mieng nh vacxin E.coli cho uong phong benh phan trang ln con.
ng a vacxin con phu thuoc vao oi tng phong benh nh phong benh dai cho
ong vat nuoi co the dung vacxin tiem nhng phong benh dai cho ong vat hoang da nh
chon, cao phai dung vacxin qua ng mieng. Chu y khong tiem vacxin vao mach mau.
3. 3. Ky thuat s dung vacxin
Kha nang tao mien dch cua vacxin phu thuoc rat nhieu vao viec s dung vacxin co
ung ky thuat hay khong. Ky thuat s dung vacxin bao gom ky thuat bao quan vacxin va
ng a vacxin.
ieu kien bao quan vacxin phai am bao, vacxin phai e ni ram mat tranh anh sang
trc tiep. Nhiet o thch hp cho viec bao quan vacxin la 2 - 40C. ac biet vacxin nhc
oc che t virus phai c bao quan - 150C.
Trc khi s dung phai kiem tra that ky, neu thay vacxin chuyen mau qua han s dung
phai huy bo. Vacxin phai at mc o bao ho ln hn hoac bang 70%.
V tr tiem phai c sat trung, dung cu tiem phai tieu oc, lieu lng tiem phai am
bao. Khi dung vacxin nhc oc nhat la loai co nha bao th khong lam vng vai vacxin.
Suc vat c tiem la nhng con khoe manh, khong tiem vacxin cho nhng con ang om,
nhng con qua gay yeu, qua non, con mi e, nhng con mi phau thuat cha lanh, nhng
con co nhieu ky sinh trung. Sau khi tiem can nuoi dng, cham soc tot.
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4. Phoi hp cac loai vacxin
Trc kia ngi ta s dung vacxin nhc oc che t vi sinh vat song a lam mat hoat
lc, vacxin nhc oc c che t vi sinh vat b lam chet bang cac tac nhan ly hoa (nhiet
o, hoa chat...). Moi loai vacxin ch mang mot mam benh va do o no ch co tac dung
phong mot benh duy nhat, o chnh la vacxin n gia.
Ngay nay, viec phoi hp nhieu loai khang nguyen trong cung mot che pham vacxin e
phong benh cho vat nuoi va ca cho ngi ngay cang c nghien cu va s dung mot cach
rong rai. Trong cung mot che pham vacxin co the cha ti hai loai khang nguyen (vacxin
nh gia) v du vacxin tu dau 3/2 phong ong thi hai benh o la tu huyet trung ln va ong
dau ln, tham ch ba hay nhieu loai khang nguyen khac nhau (vacxin t lien dch ta ln, pho
thng han, tu huyet trung, ong dau ln) va chung c goi bang ten chung la vacxin a gia.
Viec s dung nhieu loai vacxin phoi hp vi nhau trong cung mot che pham vacxin co
nhieu u iem. mot so benh truyen nhiem nhat thiet phai s dung vacxin nhieu khang
nguyen khi benh nguyen gom nhieu serotyp khac nhau ma mien dch cheo khong u e bao
ho c (nh benh l mom long mong) hoac benh do nhieu loai benh nguyen gay nen (benh
viem teo mui truyen nhiem). S ket hp nhieu serotyp hoac nhieu loai benh nguyen se lam
tang kha nang phong benh cua vacxin. Khong nhng the dung vacxin a gia cho phep giam
so lan tiem chung, nh vay giam c gia thanh cung nh giam c stress cho con vat.
Tuy nhien chat bo tr thch hp cho tng loai khang nguyen khac nhau la khong giong
nhau, v vay khong the phoi hp mot cach ngau nhien cac loai vacxin vi nhau ma viec
phoi hp nay can phai c nghien cu va th nghiem ky lng trc khi s dung no cho
cong tac phong benh.
5. Mot so ieu chu y khi s dung va bao quan vacxin
1. Bao quan vacxin trong ieu kien quy nh:
- e trong phong lanh hoac tu lanh 4 - 100C
- Khong e vacxin cho nong, tranh anh sang mat tri
- Khong gi vacxin nhiet o am (tr vacxin virus dang ti)
2. S dung:
Kiem tra lo vacxin trc khi s dung:
- Trang thai vat ly
- Mau sac
- o trong, uc
Kiem tra nhan lo vacxin:
- Ten vacxin: co ung vi nhu cau khong
- So lo, so lieu, lieu lng s dung
- Ngay san xuat, so kiem nghiem xuat xng
- Thi han s dung, quy cach bao quan
Khong dung:
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- Lo vacxin a co thay oi ve trang thai vat ly
- Nut long, a co thay oi ve trang thai vat ly
- Lo nt
- Vacxin a qua han ghi tren nhan
3. Thao tac s dung:
- Khi pha vacxin: dung cu va nc sinh ly phai c tiet trung, e nguoi
- Dung cu tiem vacxin, tay ngi pha vacxin, v tr tiem cung phai c tiet trung
- Vi vacxin song: dung cu pha thuoc phai c tiet trung va e nguoi, khong c
ra bang thuoc sat trung
- Khi dung xong dung cu phai c tiet trung tr lai, tranh e vng vai vacxin ra ngoai
- Khi dung vacxin phai a thuoc ung ng quy nh.
6. Cac phan ng khong mong muon khi tiem phong vacxin va cach khac phuc
Khi tiep nhan vacxin, c the huy ong bo may mien dch e tao khang the chong lai
tc thi, lng khang the at mc toi a sau khoang 3 tuan tiem vacxin va no duy tr trong
mot thi gian nhat nh, co khi suot ca i song cua con vat. Nhng phan ng khong mong
muon khi s dung vacxin co the la cac tac dung phu cua vacxin hay nhng tai bien do viec
s dung vacxin gay ra. Nguyen nhan cua cac phan ng nay hoac thuoc ve thuoc tnh cua
vacxin hoac do bao quan vacxin khong tot (e nhiem khuan, e ong bang vi vacxin
khong c ong bang) hoac do sai quy che s dung (sai ch nh, qua lieu) va ac biet
do anh gia chat lng, cap phep xuat xng, khong c thc hien chu ao, khong ung
quy trnh ky thuat. Nhng phan ng ngoai y muon nh vay dan en s can thiet thc hien
nghiem ngat oi vi san xuat, kiem nghiem vacxin.
6. 1. Nhng tac dung phu thng gap khi tiem phong vacxin
Thng th cac loai vacxin sau khi c tiem vao c the c coi la co hieu qua neu no
gay ra c mot phan ng nao o, tuy nhien ay ta e cap en nhng phan ng do cac
nguyen nhan tiem khong ung v tr hoac do c the qua man cam vi che pham vacxin.
Mot phan ng cuc bo tai ni tiem thng la sng o, phu ne, nga cho tiem, co khi dan
en au, co khi gay ra nhng not loet tham ch tao mot cuc cng ngay tai ni tiem, mot so
t trng hp con thay xuat hien hien tng viem hach tai ni tiem. Trng hp nhe co the
khong can can thiep, sau 24gi phan ng se mat. Trng hp ni tiem sng to va co thuy
thung dung dau nong xoa bop ni sng 2 - 3 lan/ngay, cho con vat ngh ngi an uong tot,
sau 2 - 3 ngay cac trieu chng se khoi.
Mot so phan ng toan than dang nhe co the gap la sot nhe t 0,5 - 10C co khi len ti
1,50C, con vat cam thay met moi, giam an hoac bo an, nhieu khi co phan ng non oe, tren
be mat da thay noi me ay hay noi cac ban o vi nhieu kch thc va hnh dang khac nhau.
Trieu chng nang hn co the gap la co that phe quan, ngat, ha huyet ap, benh than kinh, loan
th, liet... Neu cac phan ng the nhe ch can e vat nuoi ngh ngi ni thoang mat, cho an
thc an loang, giau am, tiem cac loai vitamin va thuoc tr sc (cafein natri benzoat 25%).
Khi con vat sot cao, cac trieu chng toan than nang co the dung khang sinh ket hp vi
thuoc ha sot (paracetamol, diclofenac 2,5%...) va cac loai vitamin (B1, C) e tiem bap,
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cham soc nuoi dng tot en khi vat nuoi het trieu chng, neu con vat sot qua cao phai
dung thuoc ha sot.
6. 2. Nhng tai bien khi s dung vacxin
Ben canh nhng phan ng co ch va nhng phan ng phu nhe co the t qua khoi, vacxin
van gay ra nhng tai bien ngoai y muon. Co rat nhieu nguyen nhan dan en tnh trang nay,
tuy nhien trc het phai ke en la do co cac thanh phan tha trong che pham vacxin (khong
phai la thanh phan khang nguyen mang tnh quyet nh) gay ra, cung co the do viec tiem
phong vacxin trong luc c the vat nuoi ang mac mot benh cap tnh hay mot so benh man tnh
nang, gia suc ang sot hay tieu chay, gia suc b suy dinh dng... Mot so loai vacxin khong s
dung cho gia suc mang thai, mot so loai ch s dung cho vat nuoi mot la tuoi nhat nh...
Ngay ca khi tuyet oi hoa chat lng cua tat ca cac loai chat bo tr trong thanh phan cua
vacxin th viec xay ra cac tai bien la ieu khong the tranh khoi.
Trong thu y, khi s dung vacxin thng gap nhng tai bien do s dung vacxin qua lieu
lng quy nh hoac tiem vacxin khi c the ang mang chnh mam benh cua khang nguyen
c a vao, v vay sau khi tiem vacxin co nhng benh se nhanh bung phat hn va nang
hn so vi khi khong tiem. Li dung ac iem nay ma ngi ta co the tiem vacxin cho vat
nuoi e chan oan sm xem vat nuoi co ang mang mam benh nao o khong.
Nhng tai bien thng gap khi s dung vacxin co the ke en la nhiem benh, cac benh
mien dch, soc qua man va nguy c bien chung cua mam benh.
a. Nhiem benh
Vacxin song, giam oc lc co the gay benh cho cac c the b suy giam mien dch. Nguy
c gay ra hien tng o la do cac thanh phan khang nguyen la vi sinh vat co the hoi phuc
tr lai, mot tac nhan b lam giam oc lc tm lai c oc tnh cua mnh va tr thanh mam
benh tac ong len c the. Trng hp nay co the xay ra khi tiem qua lieu lng vacxin quy
nh vao c the hoac qua trnh bao quan, van chuyen va s dung vacxin sai quy cach lam
cho khang nguyen tm lai c oc lc cua mnh e gay benh. Nguy c nay vacxin nga
bai liet tre nho la 10-7, ngha la c 10 trieu tre em uong vacxin Sabin th co mot em tai
nan loai nay. ieu nay khong ngan can c viec s dung vacxin nay bi le t le o c
xem la chap nhan c.
Nguy c tren cung co the xay ra do che pham vacxin nhiem cac tac nhan gay benh khac
vao. ieu nay co the han che bang cac quy trnh san xuat, bao quan va s dung chat che.
b. Benh mien dch
Th nghiem vacxin phong benh dai tren cu cho thay co xac suat gay EAE, mot benh
t mien tren he than kinh khoang 1/3000 - 1/1000. Ly do co the la do vacxin chiet xuat t
nao cho a mang theo ca nhng mau protein cua te bao than kinh, khi tao mien dch c the
(c tiem) a tao ra ca khang the chong lai cau truc than kinh cua mnh.
Vac xin phong ho ga co the gay soc kem di chng than kinh vi xac suat 10-4 - 10-6. Viec
tinh loc vacxin nay se lam tang mc an toan khi s dung nhng ong ngha vi viec lam
giam hieu qua cua no.
c. Soc qua man
Thng xay ra ngay sau khi tiem vacxin do vacxin cha lng oc to cao cha c vo
hoat triet e. Bieu hien cua qua trnh nay thng la con vat kho th, niem mac mat, mui
14
o ng, cac c ac biet la cac c van rung manh, cac trieu chng than kinh kem theo nh
giay giua, keu rong. Nang hn con co the gap la hien tng a ai lung tung, sui bot mep,
niem mac tm tai...
Khi ong vat soc qua man phai can thiep khan trng, kp thi bang cach a ngay ong
vat vao ni thoang mat yen tnh t the au cao hn uoi cho ong vat de th, xoa bop
vung ngc e tang cng ho hap va nhp tim. Dung cac loai thuoc khang Histamin nh:
Dimedron, Ephedrin, Phenegan, Adrenalin..., ket hp truyen dung dch sinh ly man hoac
sinh ly ngot co tron them vitamin B1 hoac vitamin C.
d. Tao ra nhng bien chung mi
ieu nay xay ra khi khang nguyen c a vao co cau truc giong vi khang nguyen
hien co trong c the cua vat nuoi, hien tng nay cung co the gap khi s dung cac loai
vacxin nhc oc kem chat lng. ieu o ly giai tai sao chung ta ch co the tiem vacxin
H5N2 cho ga e phong cum A H5N1 (vacxin d chung).
ngi, a co mot so tham hoa vacxin xay ra tren the gii ma lch s phat trien vacxin
a phai ghi nhan:
* Tham hoa Mulkowal: Xay ra vao thang 10 nam 1902 Mulkowal, An o, 19 ngi
chet v uon van sau khi tiem vacxin dch hach bat hoat toan te bao, o la do vacxin nay b
nhiem khuan trong qua trnh san xuat tai c s Haffkine Bombay, An o.
* Tham hoa Lucbeck: Lucbeck, c khoang 250 tre em a tnh c b cho uong vi
khuan lao oc thay v vacxin BCG khong oc. o la s nham lan trong phong th nghiem
do e chung vi khuan lao oc va vi khuan lao khong oc e san xuat vacxin. Ket qua la 72
tre chet do lao trong vong 12 thang. T tham hoa nay, ngi ta a a ra nhng quy nh
am bao an toan cho phong th nghiem va oi ngu nhan vien.
* Tham hoa Cutter: Vacxin bai liet bat hoat Salk san xuat tai My a c c quan kiem
nh quoc gia FDA cap ang ky s dung. Thang 4 nam 1955, co 120.000 tre em c tiem
lo vacxin Salk san xuat tai Cutter, California. Ket qua la 60 tre em b liet, nguyen nhan do
pham sai lam trong san xuat, x ly khong u nong o formaline nen virus bai liet cng
oc trong vacxin van con song.
* Tham hoa vacxin cum ln: Mua xuan 1976 My, t vu dch cum gay chet ngi, ngi
ta a phan lap c mot chung virus cum t ln co cong thc khang nguyen HSw1N1,
chung virus nay co cau truc khang nguyen giong vi virus cum a gay ai dch nam 1918
- 1919 vi ac tnh gay t vong cao. C quan y te My cho san xuat vacxin cum t chung
virus nay e dung rong rai trc mua phat dch. Thang 12 nam 1976, khoang 45 trieu lieu
vacxin cum ln a c dung cho ngi. Ngay sau o, nhng ngi c tiem vacxin xuat
hien hoi chng viem a than kinh nang.
II. QUY NH VE VIEC TIEM PHONG BAT BUOC VACXIN CHO GIA SUC VA
GIA CAM VIET NAM
1. Pham vi, oi tng ap dung
(1). Quy nh nay c ap dung oi vi gia suc, gia cam trong dien phai tiem phong tai
cac ho gia nh, ca nhan, c s chan nuoi ong vat tap trung.
(2). To chc, ca nhan trong nc, nc ngoai co hoat ong chan nuoi gia suc, gia cam
tren lanh tho Viet Nam phai tuan theo qui nh nay.
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2. Giai thch thuat ng
(1). Gia suc, gia cam thuoc dien tiem phong la gia suc, gia cam trong vung quy nh phai
tiem phong va co u ieu kien e tiem phong (khong tnh gia suc ang mac benh, co
cha ky cuoi, gia suc mi sinh).
(2). Tiem phong nh ky la tiem phong vao thi gian nhat nh c quy nh trong nam
tuy theo tng benh.
(3). Tiem phong bo sung la tiem phong ngoai thi gian tiem nh ky oi vi gia suc mi sinh
en o tuoi tiem phong, gia suc mi nhap an, gia suc cha c tiem trong lan tiem nh ky.
(4). Tiem phong khan cap la tiem phong khi xay ra dch benh.
3. Cac benh phai tiem phong, ty le tiem phong
(1). Cac benh phai tiem phong bat buoc, bao gom:
Benh l mom long mong
Benh dch ta ln
Benh nhiet than
Benh tu huyet trung trau bo, ln
Benh dai
Benh Newcastle
Benh dch ta vt
Benh cum gia cam (ch tiem vung dch te)
Khi tiem phong nhng benh tren ay, ty le tiem phong phai at 100% cho gia suc, gia
cam trong dien tiem.
(2). Nhng benh khac: tiem phong e khong che, thanh toan dch benh theo e ngh cua
Cuc Thu y.
4. Tiem phong oi vi tng benh
4.1. Benh l mom long mong
(1). oi tng tiem phong bao gom trau, bo, de, cu, ln nai, ln c giong.
(2). Pham vi tiem phong:
a) Tiem phong nh ky oi vi cac huyen, quan, th xa, thanh pho thuoc tnh (sau ay
goi chung la cap huyen) co bien gii vi cac nc khac; cac xa, phng, th tran (sau
ay goi chung la cap xa) a xay ra dch trong vong 2 nam trc o.
Tiem 2 lan trong nam, lan sau cach lan trc 6 thang; thi gian tiem vao thang 3 - 4
va thang 9 - 10 hang nam.
b) Tiem phong khan cap khi co dch xay ra: tiem gia suc man cam vi benh tai cac
thon, ap, xa, huyen xung quanh ni xay ra dch, tiem t ngoai vao trong. Chi cuc Thu
y quyet nh vung tiem tuy theo tnh chat lay lan cua benh.
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(3). Che o tiem phong:
a) oi vi vung bien gii tiem lien tuc 5 nam. Thi gian tiem co the keo dai, vung
tiem co the thu hep tuy theo tnh hnh dch benh tai ni o va tnh hnh dch benh
nc lang gieng.
b) oi vi vung o dch cu (bao gom vung co dch va vung b dch uy hiep) khong
thuoc vung bien gii; tiem lien tuc trong 2 nam, sau o khong tiem na neu trong thi
gian 2 nam o khong xay ra dch.
c) Nhng tnh nam trong vung d kien thanh toan benh khong phai tiem phong.
(4). Lieu lng, ng tiem, gia suc trong dien tiem theo hng dan cua nha san xuat
vacxin va Cuc Thu y.
4. 2. Benh dch ta ln
(1). oi tng tiem phong: tat ca cac loai ln trong dien tiem phong.
(2). Pham vi tiem phong: cac c s chan nuoi tap trung, chan nuoi ho gia nh trong
pham vi ca nc.
(3). Tiem phong nh ky moi nam 2 lan vao thang 3 - 4 va 9 - 10 hang nam.
(4). Tiem phong bo sung oi vi ln mi sinh, mi nhap ve cha c tiem trong thi
gian tiem nh ky.
(5). Tiem phong khan cap: khi co dch xay ra, tiem thang vao o dch trong pham vi xa co dch.
(6). Lieu lng, ng tiem, ln trong dien tiem theo hng dan cua nha san xuat vacxin.
4. 3. Benh nhiet than
(1). oi tng tiem phong: trau, bo, nga.
(2). Pham vi tiem phong: cac tnh co dch trong thi gian 10 nam tnh t o dch cuoi cung.
(4). Tiem phong bo sung oi vi gia suc mi sinh, gia suc thuoc dien tiem phong mi nhap ve.
(5). Lieu lng, ng tiem, gia suc trong dien tiem theo hng dan cua nha san xuat vacxin
4. 4. Benh tu huyet trung
(1). oi tng tiem phong: trau, bo, ln.
pham vi ca nc.
(4). Tiem phong bo sung oi vi gia suc mi sinh, gia suc thuoc dien tiem phong mi nhap ve.
4. 5. Benh ln ong dau.
(1). oi tng tiem phong: ln cac la tuoi (tr ln con ang theo me).
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(2). Pham vi tiem phong: cac c s chan nuoi tap trung, chan nuoi ho gia nh
(3). Tiem phong nh ky nam 2 lan. Co the tiem bo sung theo la tuoi.
4. 6. Benh dai
(1). oi tng tiem phong: cho, meo nuoi.
(2). Pham vi tiem phong: ca nhan, to chc trong pham vi ca nc.
(3). Tiem phong nh ky moi nam 1 lan bang vacxin te bao.
(4). Tiem phong bo sung cho cho, meo mi sinh.
(5). Lieu lng, ng tiem, gia suc trong dien tiem theo hng dan cua nha san xuat vacxin.
4. 7. Benh Newcastle
(1). oi tng tiem phong: ga cac la tuoi.
pham vi ca nc.
(3). Tiem phong nh ky moi nam 2 lan. Tuy theo la tuoi ga, loai vacxin. Co the nho
vacxin vao mat, mui hoac tiem oi vi chan nuoi ho gia nh, ca nhan. oi vi cac c
s chan nuoi tap trung tiem phong theo lch.
(4). Lieu lng, ng tiem, gia cam trong dien tiem theo hng dan cua nha san xuat vacxin.
4. 8. Benh dch ta vt
(1). oi tng tiem phong: vt, ngan cac la tuoi
pham vi ca nc.
(3). Tiem phong nh ky moi nam 2 lan, tuy theo la tuoi.
(4). Lieu lng, ng tiem, gia cam trong dien tiem theo hng dan cua nha san
xuat vacxin.
4. 9. Benh cum gia cam.
(1). oi tng tiem phong: ga, vt, ngan cac la tuoi.
(2). Pham vi tiem phong: cac a phng, cac c s chan nuoi tap trung, cac nong ho
nhng ch tiem vung dch te (cac o dch cu va cac vung co nguy c cao)
(3) Tiem phong nh ky: nam 2 lan, co tiem bo xung theo la tuoi.
(4) Lieu lng, ng tiem, gia cam trong dien tiem theo hng dan cua nha san xuat vacxin.
5. Trach nhiem thc hien
(1). To chc, ca nhan chan nuoi ong vat phai nghiem chnh chap hanh ban Quy nh nay.
(2). C quan quan ly nha nc chuyen nganh ve thu y cac tnh, thanh pho trc thuoc
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trung ng co trach nhiem lap ke hoach va to chc thc hien viec tiem phong, hng
dan viec s dung, bao quan vacxin.
(3). Cuc Thu y co trach nhiem hng dan viec tiem phong bat buoc vacxin cho gia suc,
gia cam khi co dch benh xay ra.
Chng 3
LCH S DUNG VACXIN PHONG BENH CHO GIA SUC, GIA CAM
I. MOT SO QUY NH CHUNG VE LCH TIEM PHONG

1. Trng hp khong co dch xay ra
Trong tai lieu nay trnh bay lch tiem phong chung theo quy nh cua Bo Nong nghiep
va Phat trien nong thon va hng dan cua Cuc Thu y.
Theo hng dan cua Cuc Thu y, tiem vacxin theo nh ky 2 lan/nam va co tiem bo
sung tuy loai dch benh khi ma thi gian mien dch cua gia suc, gia cam a gan het hoac
a het e tao mien dch khep kn cho vat nuoi.
Th du: Tiem vacxin chet keo phen phong benh ong dau cho ln, ln co mien dch
keo dai 7 thang nen ngi ta tiem vacxin 2 lan/nam cho ln.
Tiem vacxin Rabisin cho cho, cho co mien dch t 12 - 14 thang nen tiem nh ky cho
cho: 12 thang/lan.
Lch tiem phong cho gia suc, gia cam cac vung sinh thai va cac ieu kien san xuat
can phai thay oi va theo hng dan cu the cua cac c quan thu y vung va phai to chc
tap huan cho cac chi cuc thu y trong moi vung, v:
- Moi vung, cac benh truyen nhiem gia suc va gia cam lu hanh theo cac ac iem
dch te khac nhau. Cac ac iem dch te lai phu thuoc vao ieu kien sinh thai va kh
tng thuy van. ay la cac ieu kien lam cho dch benh phat sinh va phat trien khac
nhau trong moi vung. Th du: cac tnh mien Bac co 4 mua ro ret (xuan, ha, thu, ong).
cac tnh t Nam Trung Bo, Tay Nguyen en vung ong bang song Cu Long lai ch chia
ra hai mua la mua ma va mua kho, kh hau nong quanh nam. Tu huyet trung ln thng
xay ra dch vao mua ma pha Bac va phai tiem vacxin vao trc mua ma, khoang
thang 3 nhng mien Nam lai phai tiem vacxin vao trc mua ma, khoang thang 6.
- Lch tiem phong con phu thuoc vao ieu kien san xuat nong nghiep. Th du: to chc
tiem vacxin phong benh cho vat nuoi cac tnh pha Bac phai tiem vao hai thi iem
lam xong vu lua chiem xuan va lua mua vao khoang thang 3 - 4 va 8 - 9 hang nam.
Cac c s chan nuoi quy mo ln, cac trang trai va gia trai khong phu thuoc vao mua
vu san xuat nong nghiep th ngi ta thng to chc tiem vacxin cho gia suc, gia cam
vao trc mua dch benh phat sinh. Nhng khi tiem vacxin cho gia suc, gia cam th cac
tnh va cac c s chan nuoi can co ke hoach phu hp va tham khao cac c quan thu y
vung (7 c quan thu y vung)
19
Chung toi xin gii thieu a ch cua 7 c quan vung nh sau:
(1) C quan thu y vung I: So 50, ngo 102 Trng Chinh - Phng Mai - Ha Noi -
T: 04.38692627
(2) C quan thu y vung II: So 23 a Nang - Ngo Quyen - Hai Phong - T: 031383654
(3) C quan thu y vung III: Tp Vinh Nghe An - 0383535741
(4) C quan thu y vu ng IV: So 12 Tran Quy Cap - Hai Chau - Tp. a Nan g -
T: 05113822515
(5) C quan thu y vung V: To 5 - Khoi 8 - Tan An - Tp.Buon Ma Thuat - ac Lac -
T: 05003877795
(6) C quan thu y vung VI: So 124 Pham The Hien - phng 2 - Quan 8 - Tp.Ho Ch Minh
T: 0839830717.
(7) C quan thu y vung VII: So 88 ng Cach mang Thang 8 - Tp.Can Th - tnh Can Th
T: 0710.3820203
2. Bien phap tiem phong khi co dch xay ra:
Co the tiem vacxin vao o dch e dap dch va tiem vacxin xung quanh o dch e
khong che dch lay lan.
- Theo quy nh cua Cuc thu y mot so vacxin c tiem thang vao o dch e dap tat
dch. Th du: Vacxin dch ta ln chung C, c tiem thang vao o dch ta ln. Ln mang
trung, ang u benh se phat benh ngay va x ly kp thi (diet ln benh va khong che
c dch). Con nhng ln khoe se c mien dch sau tiem 7 - 10 ngay. Vacxin tu huyet
trung trau bo keo phen hay nhu hoa cung c tiem thang vao o dch. Trau bo a nhiem
khuan se phat benh va c ieu tr kp thi. Con an trau bo khoe se c mien dch
sau 2 tuan le, chong lai c vi khuan xam nhap.
Khi co dch muon tiem thang vao o dch tuy tng loai dch benh can hoi y kien cua
Chi cuc Thu y tnh.
- Mot so benh dch khong c tiem vacxin vao o dch v vat nuoi u benh se phat
benh nhanh, chet nhanh khong ieu tr c va khong x ly kp.
Th du 1: Vacxin cum gia cam vo hoat H5N1 khi tiem vao o dch, ga u benh se phat
benh, lay lan sang gia cam khoe, chet sau 3 gi en 3 ngay, chet hang loat.
Th du 2: Vacxin l mom long mong cam khong c tiem vao thang o dch ma phai
tiem phong cho trau bo, ln t vung an toan xung quanh o dch theo hnh xoay oc vao
gan vung co dch (vung em).
Th du 3: Vacxin nhiet than trau bo khong c tiem vao o dch v trau bo u benh se
phat benh can c ieu tr; nhng ay la benh co the lay sang ngi nen ch c tiem
vacxin bao vay o dch tao mien dch cho an trau bo khoe.
II. LCH TIEM PHONG CU THE OI VI CAC OI TNG VAT NUOI
1. Lch s dung vacxin phong benh cho trau, bo
20
Thi gian
Trnh nh ky/nam Thi gian Lieu lng
Vacxin MD Ghi chu
bay (lan) tiem (thang) (ml/con)
(thang)
100ml
Be nghe 2 - 4 thang
LMLM co 33 6 2 3 - 4, 9 - 10 3
tiem mui au
lieu
Lo 50
Nhiet than (nhc 3 - 4, 9 - 10 Be nghe 2 - 4 thang
ml/50 12 2 1
oc nha bao) (bo sung) tiem mui au
lieu
THT chung 1 (tiem trc
9 2
Robert vo hoat mua ma 1thang)
THT chung Iran 1 (tiem trc
9 2
vo hoat mua ma 1thang)
Tiem bo sung hang
THT P52 vo hoat 12 1 3-4 5
thang
THT chung T1,
5-6 1 3 - 4, 8 - 9 2-
T2, T3 vo hoat
2. Lch s dung vacxin phong benh cho ln

LCH CHUNG S DUNG VACXIN CHO LN
Th i Th i ng
nh
gian gian Li u
k /
Lo i vacxin mi n tim ng L n L n c
d ch phng (ml/con) L n con
(l n) th t ni gi ng
(thng)
2 (c thng 3 - 30 - 45 ngy Khng
1 l n/
D ch t l n 12 b 4 v 8 - 1 tu tim
sung) 9 u
u l n v 3 - 4 v >2 thng/ tim 2 l n/
9 2 2-3
ho t 8-9 l u
ul n 3 - 4 v >2 thng/ tim 2 l n/
VR2 c 8 - 12 2 1-2
8-9 l u
c >2 thng tim
T huy t trng v
6-9 2 2 l u, nh c
ho t - keo phn
1 thng l i sau 3 tu n
T huy t trng 2ml/ b p
su
20 ngy tu i
Ph
tim l n 1,
l n v ho t keo 4-5
nh c l i sau 2
phn
tu n
>2 thng tim
Leptospirosis v
6-9 2-5 l u, nh c
ho t
l i sau 3 tu n
2 tu n tu i - 2
L m m long 3 - 4 v 2 l n/
6 2 thng tu i tim
mng 9 - 10
l u
21
LCH TIEM PHONG VACXIN CHO LN CON
LCH TIEM PHONG VACXIN CHO LN HAU B
LCH TIEM PHONG VACXIN CHO LN NAI
Ghi chu: - Respisure: Vacxin phong benh Suyen do Mycoplasma hyopneumonia (Hang
Prizer san xuat)
- Pr - Vac - Plus (Pseudorabies nhc oc t nhien)
- Farrowsure B (Parvovirus - 6 chung Leptospira va ong dau ln)
22
3. Lch s dung vacxin phong benh cho ga
LCH TIEM PHONG VACXIN CHO AN GA GIONG THT
LCH TIEM PHONG VACXIN CHO AN GA GIONG TRNG
LCH TIEM PHONG VACXIN CHO AN GA THNG PHAM TRNG
23
LCH TIEM PHONG VACXIN CHO AN GA THNG PHAM
4. Lch s dung vacxin phong benh cho vt - ngan
5. Lch s dung vacxin phong benh cho cho - meo
24
Chng 4
MOT SO VACXIN A C S DUNG CO HIEU QUA VIET NAM
I. VACXIN DUNG CHO TRAU BO

1. VACXIN NHA BAO NHIET THAN ONG KHO
ac tnh:
- La vacxin song, ong kho, cha nha bao nhiet than nhc oc chung Stern 34.
- La vacxin song, ong kho, cha nha bao nhiet than nhc oc chung Stern 34 F2.
- Vacxin an toan, tao mien dch tot khi tiem cho gia suc.
- Chung nha bao nhiet than Stern 34 F2 co tnh on nh cao, hoan toan vo oc vi ngi
va gia suc.
Ch nh:
Dung gay mien dch chu ong phong benh nhiet than cho trau, bo, de, cu, nga va ln
khoe manh.
Thanh phan:
- Moi lieu vacxin cho trau bo cha 107 nha bao nhiet than nhc oc chung Stern 34F2.
- Moi lieu vacxin cho de, cu, ln cha 5 x 106 nha bao.
- Chat bo tr: Sa khong kem.
Cach s dung:
- Dung nc sinh ly e pha vacxin vi lng, moi lieu ghi tren nhan chai bang 1ml.
- Lac ky vacxin trc khi dung.
- Tiem di da cho trau bo tren 4 thang tuoi, lieu 1ml/con.
- Tiem di da cho de, cu, ln tren 3 thang tuoi, lieu 0.5 ml/con.
Chu y:
- Sau khi pha s dung vacxin trong ngay.
- Chai vacxin dung xong phai c ngam vao chat sat trung hay luoc soi trc khi bo i.
Trnh bay: ong chai 10 lieu, 20 lieu.
Bao quan:
- e vacxin nhiet o 20C - 80C. Khong e vacxin vao ngan ong.
- Han dung 6 thang nhiet o thng, ni mat, toi, kho.
Nha san xuat va phan phoi:
25
Cong ty Thuoc thu y Trung ng
29 Nguyen nh Chieu, quan I, TP. Ho Ch Minh - T: (8408) 3.8225063
Chi nhanh:
So 164 pho Phng Liet, Q. Thanh Xuan, Ha Noi - T: (84.4) 8691003
2. VACXIN L MOM LONG MONG (FMD)
(Foot and Mouth Disease vaccine)
- Gom bon loai: O Manisa, O Mannisia + A22, O Manisa + Asia 1 Shamir, O Manisa +
A22 + Asia 1 Shamir (Hien nay theo yeu cau cua Cuc thu y, Cong hoa Lien bang Nga a
bo sung them Amay 97 e phu hp hn).
- c san xuat tai Federal Centre for Animal Health (FGI ARRIAH), Cong hoa
Lien bang Nga.
- a c Vien Thu y khao nghiem (vi s cho phep cua Bo Nong nghiep & PTNT),
at ket qua tot va chnh thc c phep lu hanh tai Viet Nam.
Thanh phan cua vacxin:
- Khang nguyen virus L mom long mong c nuoi cay tren te bao BHK-21, moi lieu
vacxin cha toi thieu 6PD 50 (Lieu bao ho 50%).
- Chat vo hoat: 1,2 aminoethyleneimine.
- Chat bo tr: Nhu dau.
Cong dung:
Vacxin dung phong benh L mom long mong cho ln va cac loai ong vat nhai lai
khoe manh.
Ch nh va lieu lng s dung:
- Loai ch nh: Dung tiem phong benh cho ln va cac loai nhai lai.
- Lieu dung: Ln: Tiem bap tht, 2ml/con
Trau bo: Tiem di da, 2ml/con
De, cu: Tiem di da, 2ml/con
Chu y:
- Khong dung vacxin cho vat nuoi b benh hay om yeu.
- Lo vacxin phai c gi lanh cho en khi dung.
- Khong dung lo vacxin co hien tng b nt, v.
- Sau khi m, lo vacxin dung trong 10 gi.
- Bm tiem va kim tiem phai c tiet trung trc khi s dung va thay kim thng xuyen.
Trnh bay: Chai 20ml, 50ml, 100ml, 200ml.
26
Bao quan:
- Nhiet o bao quan 20C en 80C.
- Khong c e vacxin vao ngan ong.
- Trong qua trnh van chuyen phai gi trong thung xop a lanh (hoac a kho), tranh
nong va anh sang trc tiep.
- Han dung 18 thang ke t ngay san xuat khi bao quan 20C en 80C.
Nha nhap khau va phan phoi: Cong ty Thuoc thu y Trung ng
Chi nhanh:
3. VACXIN POSI - FMD (TRIVALENT)
(Vaxin vo hoat, dang dau, tam gia phong benh L mom long mong. Dung ln, trau, bo,
de va cu.)
Thanh phan:
Moi lieu vacxin gom co:
- Virus c nuoi cay tren moi trng te bao BHK

- Chat vo hoat: Ethylenimine
- Chat bo tr: Dau montanide ISA 206
- Chat bao quan: Thiomersol
- Chat lam vo hoat cho BEI: Dung dch muoi thiosulphate.
Ch nh: Dung tiem phong cho ln, trau bo, be, de va cu e phong chong benh L
mom long mong.
Cach dung va lieu lng:
- Lo vacxin phai c gi lanh cho en khi s dung va moi lo phai c lac eu trc
khi tiem.
- Bm tiem va kim tiem phai c tiet trung trc khi s dung.
- Vacxin c tiem sau bap tht nhng vung da sach, kho e tranh b nhiem trung.
Tiem vung gia co. oi vi ln tiem vung c pha sau tai.
- Thi gian tiem:
27
+ Tiem phong lan au tien: 4 thang tuoi (trau, bo, de, cu).
+ Tiem phong lan au tien: 2 thang tuoi (ln).
+ Tiem tang cng: 9 thang sau mui au (trau, bo, de, cu).
+ Tiem nhac lai: c 12 thang sau o (trau, bo, de, cu).
+ Tiem nhac lai: c 6 thang sau o (ln).
- Lieu dung:
+ Trau bo, be va ln: 2ml/con.
+ Cu, de: 1ml/con
Chong ch nh: Khong
Chu y:
- Khong co phan ng phu.
- Mien dch keo dai 24 thang.
- Can tranh tap nhiem vi khuan moi khi rut vacxin POST - FMD Trivalent ra khoi lo.
- Huy bo vacxin tha sau moi ngay s dung.
- e xa tam tay tre em.
Trnh bay: Chai 30ml, chai 50ml, chai 200ml
Bao quan: nhiet o t 2-80C, tranh anh sang va ong a.
Han dung: Ch nh tren nhan
Nha san xuat va phan phoi: Cong ty Pfizer - VN,
Tang 7, phong 7.IB, 364 ng Cong Hoa, quan Tan Bnh, TP. Ho Ch Minh.
Tel: (84.8) 38122464, Fax: (84.4) 38122712
4. VACXIN DECIVAC FMD DOE - TRIVALENT
(Vacxin L lom long mong tam gia)
Mo ta san pham:
- Vacxin cha khang nguyen virus L mom long mong type O1, A17/82 va Asia 1 vo
hoat, c phoi che vi chat bo tr nhu dau kep la dau khoang e bao am tao mien dch
sm va keo dai.
- Vacxin c kiem tra o an toan, hieu qua va ch nh tao mien dch chu ong cho cac
ong vat mong guoc chan, ac biet la bo, trau, cu, de va ln.
Hng dan s dung:
- Chat bo tr nhu dau kep co the b tach nhe ra trong qua trnh bao quan, tuy nhien chat
lng cua vacxin khong b anh hng.
28
- Lo vacxin can c lac ky trc khi lay ra e tiem.
- Vacxin phai c tiem bap vao vung co hoac c ui. Khi tiem xong can xoa nhe nhang
vung tiem e vacxin phan bo eu tren vung mo ln.
- Can than trong tiem tng con trong an ung theo lieu khuyen cao ghi phan sau.
Lieu lng: bo, trau va ln: 2ml; cu va de: 1ml.
Chng trnh tiem phong:
* MDA: khang the me truyen sang con.

* Khi virus LMLM gay ra dch a phng, can tiem nh ky 6 thang mot lan
Tac dung phu: Vacxin c vo hoat hoan toan, khong gay bat ky phan ng bat li nao.
Trong thc te khong co bien oi than nhiet sau khi tiem vacxin. Co the co sng nhe ni
tiem mot so ong vat va thng het sng sau vai ngay.
Bao quan: Vacxin phai c bao quan nhiet o t 2-80C. Nhiet o tren 80C gay anh
hng bat li en kha nang tao mien dch cua vacxin. Can than trong khong e vacxin b
ong a. Vacxin a b ong a phai loai bo. e duy tr nhiet o mong muon trong suot qua
trnh van chuyen, can s dung tui a kho ong lanh va thung cach nhiet.
Khi bao quan va van chuyen ung theo yeu cau ky thuat, vacxin co hieu lc trong thi
gian toi thieu la 12 thang.
Trnh bay: 20ml, 50ml va 100ml trong lo nha PET.
Chu y:
- Chat lng cua san pham nay c kiem tra ky lng theo yeu cau bat buoc trc khi
xuat xng.
- Nh tat ca cac loai vacxin, co the xay ra cac thao tac sai oi vi san pham bao gom bao
quan khong ung cach, nhiet o khong bao am trong qua trnh bao quan,v.v.
- Tiem khong u lieu va dung vacxin khong ung cach, dung vacxin khi dch bung phat,
ong vat b nhiem trc khi mien dch kp tao ra co the dan en that bai trong tiem phong
mac du vacxin co chat lng tot.
- Cac yeu to gay stress ong vat a c tiem phong (thi tiet qua lanh, van chuyen
ong vat ng dai v.v) dan en ap ng mien dch di mc toi u.
- Hiem khi xay ra trng hp ong vat co phan ng qua man sau khi tiem phong. Trong
trng hp nay co the cha bang nhng san pham khang histamine thong thng. ay
la hien tng t nhien thong thng, ch xay ra n le trong khi ngan con vat khac tiem
vacxin cung lo, cung thi iem th eu bnh thng. Hn na, phan ng nay khong ch do
29
vacxin ma quan sat thay nhng trng hp khi s dung nhng che pham protein, phan
oan cua protein hoac chat gay d ng.
- Khong can thi gian ngng s dung vacxin trc khi giet tht hoac lay sa lam thc
pham, vacxin khong gay anh hng en sc khoe con ngi.
Nha phan phoi: Cong ty thuoc Thu y TW (NAVETCO), so 2 Nguyen nh Chieu, quan
1 TP. Ho Ch Minh. T: (84.4): 38225063, Fax: (84.4)38225060
5. VACXIN AFTOVAX
(Vacxin vo hoat va thuan khiet co chat bo tr phong benh L mom long mong cho ong
vat nhai lai)
Thanh phan:
- Khang nguyen: Virus L mom long mong vo hoat co cha mot hoac nhieu chung
huyet thanh lu hanh
- Moi lieu cha t nhat 3DP50 cho moi hieu gia.
- Aftovax lu hanh Viet Nam la loai tam gia 0, A, Asia 1, typ 0 co hai chung O Manisa
va 0 3039, typ A co hai chung A 22 va A Malaysia 97, Asia 1 Shamir, san xuat rieng cho
Viet Nam, phu hp vi ieu kien dch te mi.
- Chat bo tr: Hydroxyt Aluminium va Saponine.
Ch nh: Phong benh L mom long mong cho trau, bo, de, cu.
Hng dan s dung:
- Tron dung dch that ky bang cach xoay tron chai thuoc trc khi s dung khoang 20 lan.
- Tiem di da.
- Lieu dung (xem nhan), khong ke tuoi tac va trong lng gia suc.
+ Tiem phong lan au: Tiem hai lan cach nhau 3-4 tuan. Lan th nhat thc hien tren
gia suc non 2 tuan tuoi (co me cha tiem phong) hoac tren gia suc non 2,5 thang tuoi (co
me a tiem phong).
vung co dch, lan tiem au tien can c thc hien tren tat ca gia suc non t 2 tuan tuoi.
+ Tiem phong nhac lai: Thong thng, tiem nhac lai can c thc hien 6 thang mot lan
tuy thuoc vao tnh hnh dch benh va phap che cua a phng.
Chong ch nh: Khong
Chu y:
- Ch tiem phong cho gia suc khoe manh.
- Thao tac can than oi vi vat nuoi mang thai.
- Bao quan vacxin trong ieu kien vo trung thong thng, khi a m nap lo, vacxin
ch c s dung trong vong 36 gi vi ieu kien phai c bao quan nhiet o 2-80C va
khong c am kim vao nut cao su nhieu lan.
- Sau khi tiem phong co the co viem nhe cho tiem va/hoac co the kem sot nhe trong
mot thi gian ngan. Rat hiem khi xay ra trng hp qua man.
30
Bao quan: nhiet o t 2-80C, trong bong ram, khong c lam ong lanh.
Trnh bay: Chai 50ml
Nha san xuat: GRANDES PROPHYLAXIES GLOBAL ENTERPRISE.
Unit 613. Meling Poont Tower - 2 ngo - c Ke - quan I, TP. Ho Ch Minh
Tel/Fax: (84.8) 38279082
Nha phan phoi: Cong ty Thuoc thu y Trung ng
Chi nhanh: So 164 pho Phng Liet, Q. Thanh Xuan, Ha Noi - T: (84.4) 3.8691003
6. VACXIN L MOM LONG MONG
(Vacxin vo hoat, dang dau, n gia phong benh L mom long mong. Dung cho ln,
trau, bo, de va cu)
Thanh phan: Moi lieu vacxin gom co:
ac tnh:
- Virus c nuoi cay tren moi trng te bao BHK
- Chat vo hoat: Ethyleneimine
- Chat bo tr: Dau montanide ISA 206
- Chat bao quan: Thiomerol
- Chat lam vo hoat cho BEI: Dung dch muoi thiosulphate
Ch nh: Dung tiem cho ln, trau, bo, be, de va cu e phong chong benh L mom
long mong.
Hng dan s dung:
khi tiem.
- Vacxin c tiem sau bap tht nhng vung da sach, kho e tranh b nhiem trung.
Tiem vung gia co. oi vi ln tiem vung c pha sau tai.
- Thi gian tiem:
+ Tiem phong lan au tien 4 thang tuoi (trau, bo, de, cu).
31
+ Tiem phong lan au tien: 2 thang tuoi (ln).
+ Tiem phong tang cng: 9 thang sau mui tiem au tien (trau, bo, de, cu).
+ Tiem lap lai: c 12 thang sau o tiem lai (trau, bo, de, cu).
+ Tiem lap lai: c 6 thang sau o tiem lai (ln).
- Lieu dung:
+ Trau, bo, be va ln: 2,0ml
+ Cu, de: 1,0ml.
Chong ch nh: Khong
Mien dch: Mien dch keo dai trong 24 thang. Tuy nhien viec tiem phong hang nam van
c nhac lai tuy tnh hnh dch te a phng.
Trnh bay: Chai 30ml, chai 100ml, chai 200ml
Bao quan:
- nhiet o t 2-80C, tranh anh sang va ong a.
- e xa tam tay tre em.
Han dung: Ch nh tren nhan
Nha phan phoi: Cong ty CP Thuoc va Vat t thu y (Hanvet)
88 Trng Chinh - ong a - Ha Noi, Tel: (84.4) 38691156.
7. VACXIN VO HOAT LMLM NH GIA TYP O - ASIA
Thanh phan:
- Khang nguyen virus co ac Typ O LMLM OXNC/92 va Typ Asia - 1 (Asia 1 AKT/03)
a vo hoat.
- Nhu dch kep (w/o/w).
- Khang sinh va chat bao quan.
ac tnh:
- Virus nuoi cay qua moi trng te bao BHK21.
- Vo hoat bang BEI.
- Nhu hoa bang ta dc dau.
Ch nh:
- Phong benh LMLM typ O va typ Asia 1 gay ra trau, bo, de, cu, ln.
- Khong che, dap tat o dch.
- Ngan chan, bao vay s lay lan cua o dch.
Hng dan s dung:
32
- Lac ky chai vacxin trc khi dung, sat trung v tr tiem, thay kim trong qua trnh
tiem, dung kim vi o dai hp ly e tiem vao bap.
- Trau, bo: tiem bap co
- Ln: tiem bap c sau tai
- De, cu: tiem bap ui sau
Lieu lng:
Trau, bo di 1 tuoi: 1ml/con
Trau, bo trng thanh: 2ml/con
Trau, bo ln (tren 300kg): 3ml/con
De, cu con: 0,5ml/con
De, cu ln: 1ml/con
Chu y:
- Sau khi tiem phong 1-3 ngay, v tr tiem co the sng, gia suc sot hoac giam an. Tuy theo s
khac biet tng ca the co the gay phan ng qua man. e oi pho vi nhng phan ng tren nen
dung thuoc chong d ng, v du: Adrenalin, Cafein, Atropin (tiem bap cho gia suc).
- Khong tiem di da hay tiem vao mo m.
Khuyen cao:
- Do ac iem dch te va kha nang lay truyen cua benh LMLM, tiem vacxin ch la mot
trong nhng bien phap tieu diet va phong benh.
- Ket hp ong nhat cac bien phap an toan sinh hoc, phong tr tong hp nh: phong toa,
cach ly, tieu oc.
Bao quan: Bao quan vacxin nhiet o 2-80C, tranh e ong, tranh anh nang chieu trc tiep
Han dung: 12 thang
8. VACXIN VO HOAT LMLM CHUNG O TRAU BO
(Nhu dch tiem, mau trang sa hoac phan hong, hi nht)
Thanh phan:
- Khang nguyen nc (140S > 1,2mg/ml)
- Nhu dch dau
- Khang sinh va chat kh trung
ac tnh:
- Virus nuoi cay qua te bao BHK21
- Vo hoat bang BEI.
33
- Nhu hoa kep bang khoang dau.
- Vacxin phong benh LMLM cho ong vat nhai lai nh: trau, bo, de
- at tieu chuan quoc te, a c kiem tra an toan va kiem tra hieu lc.
- Sau khi tiem vacxin 15 ngay co ap ng mien dch va keo dai 6 thang. Trong thi gian
o gia suc co bao ho c 90% vi lieu cong cng oc 100000 ID 50 virus oc lc gay
benh LMLM.
Lieu lng:
- Trau, bo trng thanh: 3ml/con
- Be, nghe: 2ml/con
- De trng thanh: 1,5ml/con
- De con: 1ml/con
Bao quan: Gi vacxin nhiet o 4 - 80C, ni kho, tranh anh sang trc tiep.
Han dung: 12 thang
Chu y:
- oc ky hng dan trc khi dung.
- Kiem tra sc khoe cua con vat trc khi tiem phong.
- Tiem vacxin ch la mot trong nhng bien phap e phong benh. Muon phong benh hieu
qua phai tien hanh nhng bien phap an toan sinh hoc, phong tr tong hp nh: phong toa,
cach ly, tieu oc.
9. VACXIN TU HUYET TRUNG TRAU, BO CHUNG P52, NHU DAU
ac tnh:
Vacxin c che t vi khuan Pasteurella multocida serotyp B:2, chung P52; co tnh an
toan cao, thi gian mien dch keo dai 12 thang.
Ch nh: Dung phong benh Tu huyet trung cho trau, bo, be, nghe khoe manh.
Thanh phan:
- Moi 1ml vacxin cha 10 ty te bao vi khuan.
- Chat bo tr: Nhu dau
Cach s dung: Tiem bap tht: lieu 2,0ml/con cho trau, bo, be, nghe khoe manh t 6
thang tuoi tr len.
Chu y:
- Trong nhng vung luon co dch benh Tu huyet trung xay ra, nen tiem nhac lai sau 9
thang. cac vung an toan thi gian tiem nhac lai co the 12 thang.
- Khong dung nhng lo vacxin b v, nt hoac co hien tng tach pha nc.
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- Lay chai vacxin ra khoi ni bao quan, e vacxin at en nhiet o phong, lac ky trc
khi dung. S dung het vacxin trong ngay.
- Khi bao quan thi gian dai nhiet o 2-80C, co the xuat hien lang can di ay
chai. Hien tng nay la bnh thng va khong anh hng en chat lng cua vacxin.
Trnh bay: Chai 20ml cha 10 lieu, 10ml cha 25 lieu.
Bao quan:
- Nhiet o t 2-80C, khong e vacxin vao ngan ong, tranh anh sang mat tri.
- Thi han bao quan: 12 thang ke t ngay san xuat.
Nha san xuat va phan phoi: Cong ty Thuoc thu y Trung ng
Chi nhanh:
10. VACXIN HIPRAMASTIVAC
Trong 1 lieu (3ml) co:
- Staphylococcus aureus TC5 vo hoat 10.
- Staphylococcus aureus TC8 vo hoat 10.
Hng dan s dung:
- Nang nhiet o vacxin len mc 15 - 200C.
- Lac eu vacxin trc khi s dung
- Tiem c co.
- Lan au: mot mui (3ml) bat ky giai oan nao cua chu ky cho sa, tiem nhac lai 4
tuan sau o.
- Lan 2: 6 thang tiem lai mot lan.
Ch nh: S dung phong benh viem vu cho bo sa.
Nha phan phoi: Cong ty Thuoc thu y Xanh (GREENVET)
186 Trng Chinh, ong a, Ha Noi - Tel: (84.4) 35659240, Fax: (84.4) 35659593.
II. VACXIN DUNG CHO LN
1. VACXIN PORCILIS CSF LIVE
(Cong cu thong nhat e kiem soat dch ta ln)
Mo ta: Porcilis CSF Live la vacxin song nhc oc ong kho. Moi lieu cha t nhat 103
TCLD50 virus dch ta chung Nhat Ban dong GPE nhc oc.
Ch nh:
35
- Tao mien dch chu ong cho ln phong benh dch ta ln (Classical Swine Fever, Hog
Cholera).
- Sau khi tiem 3 ngay ln a c bao ho do o rat thch hp dung e dap dch.
Ln tht: Tiem lan au luc 1-2 thang tuoi tuy theo mc o khang the me truyen. Lan hai
tiem sau lan au 4 tuan.
Ln giong: Tiem lan au luc 1-2 thang tuoi tuy theo mc o khang the me truyen, lan
hai tiem sau lan au 4 tuan. Tiem nhac lai moi 6 thang.
Co the tiem toan an ln giong ma khong gay anh hng g en qua trnh mang thai.
Lieu lng va cach s dung:
- Pha vacxin vao lo nc pha tieu chuan i kem, moi lieu 2ml cho moi la tuoi.
- Tiem bap tht.
Han ngng dung: Khong can thi gian ngng dung vacxin trc khi giet tht.
Quy cach: Lo 50 lieu.
Bao quan: 2-80C, tranh anh sang. Lo nc pha bao quan nhiet o phong (15-250C).
Cac thong tin khac: Porcilis CSF Live tao mien dch nhanh va bao ho manh me (t ngay
th 4 sau khi tiem phong).
Chu y:
- Ch tiem phong cho ln khoe manh.
- S dung ngay lo vacxin sau khi pha.
- Dung dung cu tiem phong vo trung.
Nha san xuat:
Cong ty INTERVET - VIETNAM, A PART OF SCHERING PLOUGH CORPORATION,
50B ang Dung - quan I - TP. Ho Ch Minh - Tel: (84.8) 38245077, Fax: (84.8)38245077.
2. VACXIN DCH TA LN ONG KHO
Thanh phan:
- Moi lieu vacxin cha t nhat 100 PD50 virus dch ta ln nhc oc chung C.
- Chat bo tr: Sa khong kem.
ac tnh:
- La vacxin nhc oc, ong kho, san xuat t virus dch ta ln chung C.
- Vacxin an toan, tao mien dch nhanh, manh va keo dai.
Ch nh: Dung gay mien dch chu ong phong benh dch ta ln cho ln khoe manh.
Hng dan s dung:
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- Tiem di da vung sau goc tai hoac mat trong ui.
- Pha vacxin bang nc sinh ly vo trung a lam lanh sao cho 1ml cha 1 lieu vacxin.
Lac eu, tiem 1ml/con.
- Ln con theo me: tiem 2 lan
+ Lan 1: 15-30 ngay tuoi.
+ Lan 2: 30-45 ngay tuoi (15 ngay sau khi tiem mui au).
- Ln nai:
+ Nai hau b: Tiem phong 2 tuan trc khi phoi giong.
+ Nai mang thai: 1 thang trc khi e.
- c giong: nh ky moi nam tiem 2 lan.
Chu y:
- Sau khi pha, chai vacxin phai c gi trong nc a, tranh anh sang mat tri va dung
trong vong 2-3 gi.
- Dung xong phai ngam chai vacxin vao chat sat trung hoac luoc soi trc khi bo i.
Trnh bay: Vacxin ong chai 10 lieu hoac 25 lieu.
Bao quan: e vacxin nhiet o 2-80C. Khong e vacxin vao ngan ong.
Chi nhanh: So 164 pho Phng Liet, Q. Thanh Xuan, Ha Noi - T: (84.4) 8691003
3. VACXIN DCH TA LN NHC OC CHUNG GPE-SWIVACC
Thanh phan:
- Moi 1ml vacxin cha t nhat 103TCID50 virus dch ta ln nhc oc chung GPE.
- Chat on nh: Lactose, PVP.
ac tnh:
Vacxin c che t virus dch ta ln nhc oc chung GPE tren te bao than chuot lang,
co tnh an toan cao, ap ng mien dch nhanh va keo dai toi thieu 12 thang.
Ch nh: Dung phong benh dch ta cho ln khoe manh.
Cach s dung: Tiem bap tht hoac di da; lieu 1ml/con.
Chu y:
- Lo vacxin phai c gi lanh cho en khi dung xong.
- Khong dung lo vacxin b v, nt.
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- Sau khi m, lo vacxin phai c dung het trong 4 gi.
- Thng xuyen thay kim trong khi tiem.
Trnh bay: Chai 10 lieu, 20 lieu, 50 lieu.
Bao quan:
- Nhiet o t 2-80C, khong e vacxin vao ngan ong, tranh anh sang mat tri.
- Thi han bao quan: 18 thang ke t ngay san xuat.
San xuat tai: Cong ty Kyoritsu Seiyaku, Nhat Ban. Ra chai va phan pho tai: NAVETCO
So: 29 Nguyen nh Chieu, quan 1, TP. Ho Ch Minh. T: (84.8) 38225063 -(84.8) 38225955
4. VACXIN DCH TA LN TE BAO
(San pham hp tac nghien cu gi Phong th nghiem thu y Quoc gia (AAHL) Uc va
NAVETCO - Viet Nam, d an CARD-AUSAID)
Ten san pham: Vacxin dch ta ln te bao
Mo ta:
- Vacxin ong kho, dang te bao. Virus dch ta ln nhc oc chung C, moi lieu vacxin
cha t nhat 103TCID50.
- Chat on nh: Sa khong kem.
- ng tiem: Bap tht hoac di da.
Ch nh: Dung phong benh dch ta cho ln khoe manh.
Hng dan s dung:
- Tiem bap hoac di da.
- Lieu dung: 1ml/con.
- Ln con theo me: Tiem 2 lan.
+ Lan 1: 15-30 ngay tuoi
+ Lan 2: 30-45 ngay tuoi (15 ngay sau khi tiem lan dau).
- Ln nai:
+ Nai hau b: Tiem 2 tuan trc khi phoi giong.
+ Nai mang thai: 01 thang trc khi e.
- c giong: nh ky moi nam tiem 2 lan.
Chu y:
38
- Pha vacxin bang dung dch nc muoi sinh ly vo trung a e lanh.
- Khong dung lo vacxin co hien tng b v, nt.
- Sau khi m, lo vacxin dung trong 04 gi.
- Bm tiem va kim tiem phai c tiet trung trc khi s dung, thay kim thng xuyen.
Chong ch nh: Khong dung cho ln ang b benh hoac om yeu.
Trnh bay: Chai 10 lieu, 20 lieu, 50 lieu, 100 lieu/chai.
Bao quan:
- Nhiet o bao quan 2-80C.
- Khong c e vacxin vao ngan ong.
- Trong qua trnh van chuyen phai s dung xe lanh chuyen dung hoac bao quan vacxin
trong thung xop co a lanh (hoac a kho), tranh nong va anh sang trc tiep.
Han dung: 18 thang ke t ngay san xuat (khi bao quan 2-80C)
5. VACXIN MYVAC HC (GE)
Thanh phan: Trong 1ml vacxin co virus gay benh dch ta ln chung GPE-ve co toi thieu
103.0 TCID50.
Vacxin c che di dang ong kho.
ac tnh dc ly cua san pham:
- Sau khi tiem vacxin, chung GPE - ve c tru on nh hach amidan, ao thai qua phan
va nc tieu trong 10 ngay sau tiem. S bao ho cua mien dch c hnh thanh sau khi tiem
3 ngay nhng sau 2-3 tuan khang the trung hoa mi bat au tang len va ton tai tren 2 nam.
- ap ng mien dch xuat hien sau mot lan tiem bap. ap ng mien dch co tac dung
nhanh, manh, keo dai.
- Sau khi tiem vacxin, ln co kha nang khang lai s nhiem virus bat au t ngay th 5.
Khang the co mat trong huyet thanh t ngay th 5, at nong o cao nhat sau gan 1 thang
va se duy tr nong o nay trong suot cuoc i.
- S hien dien cua khang the trung hoa trong huyet thanh co moi quan he chat che vi
s khang lai kha nang cong cng oc cua virus theo hng mot chieu.
Hng dan s dung:
- Vacxin dung cho tat ca cac loai ln: ln con, ln tht, ln nai, ln c, ln giong.
- Lam lanh 50ml, 20 ml hoac 10ml dung moi en 40C (dung vi chai vacxin 50 lieu, 20
39
lieu hoac 10 lieu). Cay phan gia nap chai, dung bm tiem va au kim vo trung a 5ml
dung moi a c lam lanh vao chai vacxin bang cach am mui kim xuyen qua nap cao
su. Lac nhe e hoa tan hoan toan va se thu c vacxin hoan nguyen. Hut tr lai vacxin
vao lo cha dung moi se c mot lo vacxin co 50 lieu, 20 lieu hoac 10 lieu (1ml/con/lieu).
Vacxin sau khi pha nen s dung cang sm cang tot.
- Tiem bap: 1ml/con/lieu
- Ln con: mui tiem au tien vao 30-35 ngay tuoi, mui tiem th 2 sau mui th nhat 3-4 tuan.
- Ln nai hau b: tiem mui au tien vao thang tuoi th 7-8 hoac trc khi phoi giong.
- Ln c giong: tiem moi nam mot lan.
Ch nh: Vacxin tao mien dch chu ong tren ln e chong lai benh dch ta ln.
Trnh bay: Chai 50 lieu, 20 lieu va 10 lieu
Nha san xuat: Malaysia Vaccines and Pharmaceutical Sdn. Bhd.
Lot 11182 Batu20, Jalan Puchong - Kaijang
Palau Meranti, 471000 Puchong
Selangor Darul Ehsan.
186 Trng Chinh, ong a, Ha Noi. Tel: (84.4) 35659240, Fax: (84.4) 35659593
6. VACXIN PEST VAC
(Vacxin song nhc oc nga benh dch ta ln chung C nuoi cay tren mo te bao than ln)
Thanh phan: PEST - VAC: Vacxin song nhc oc dang ong kho, vi virus dch ta ln
co ien chung C c cay truyen t te bao than ln. Trong qua trnh nuoi cay co s dung
Penicilin va Streptomycin lam chat ngng trung, bao quan. Vacxin co o tinh khiet tuyet oi.
Hng dan s dung:

- Pha mot lieu vacxin vi 2ml nc pha bang bm tiem vo trung.
- Tiem sau vao bap tht hoac tiem di da vi lieu 2ml.
40
Chu y:
- Khong tiem phong neu nghi ln b benh hoac tnh trang sc khoe khong tot.
- Dung cu tiem phai c tiet trung bang cach un soi, khong s dung hoa chat e sat
trung dung cu tiem.
- S dung het lo vacxin khi a pha. Huy tat ca chai lo va thuoc d tha.
- Phan ng d ng rat t xay ra. Neu co th s dung Epinephrine hoac Atropine.
Bao quan: Bao quan nhiet o 2-70C, tranh ong a.
Trnh bay: Lo 10 lieu, 25 lieu, 50 lieu.
Han s dung: Ghi tren bao b.
Nha phan phoi: Cong ty CP Phat trien Cong nghe Nong thon (RTD)
Khu CN An Khanh - Hoai c - Ha Noi. Tel: (84.4) 0343650574.
7. VACXIN DECIVAC FMD DOE - MONOVALENT
Mo ta san pham:
- Vacxin cha khang nguyen virus l mom long mong typ O1 vo hoat, c phoi che vi
chat bo tr nhu dau kep la dau khoang e am bao tao mien dch bao ho sm va keo dai.
- Vacxin c kiem tra o an toan, hieu qua va ch nh tao mien dch chu ong cho cac
ong vat mong guoc chan, ac biet la bo, trau, cu, de va ln.
Hng dan s dung:
- Chat bo tr nhu dau kep co the b tach nhe ra trong qua trnh bao quan, tuy nhien chat
lng cua vacxin khong b anh hng.
- Lo vacxin can c lac ky trc khi tiem. Vacxin phai c tiem bap vao vung co
hoac c ui. Khi tiem xong rut kim tiem ra can xoa nhe nhang vung tiem e vacxin phan
bo eu tren vung mo ln.
- Can than trong tiem tng con trong an ung theo lieu khuyen cao ghi phan sau.
- Lieu lng: Bo, trau va ln: 2ml/con. Cu va de: 1ml/con.
* MDA: khang the me truyen sang con.

* Khi virus LMLM gay ra dch a phng, can tiem nh ky 6 thang mot lan.
41
Tac dung phu: Vacxin c vo hoat hoan toan, khong gay bat ky phan ng bat li nao.
Trong thc te khong co bien oi than nhiet sau khi tiem vacxin. Co the co sng nhe ni
tiem mot so ong vat va thng t mat i sau vai ngay.
Bao quan:
- Bao quan ung yeu cau ky thuat la yeu to cc ky quan trong bao am hieu qua cua
vacxin. Vacxin phai c bao quan nhiet o t 2-80C. Nhiet o tren 80C gay anh hng
bat li en kha nang tao mien dch cua vacxin. Can can trong khong e vacxin b ong a.
Vacxin a b ong a phai loai bo. e duy tr nhiet o mong muon trong suot qua trnh van
chuyen, can s dung tui a kho ong lanh va thung cach nhiet.
- ieu cc ky quan trong la phai e vacxin trong tu lanh trong suot qua trnh bao quan.
- Khi bao quan va van chuyen ung theo yeu cau ky thuat, vacxin co hieu lc trong thi
gian toi thieu la 12 thang.
Trnh bay: Lo 20ml
Chu y:
- Chat lng cua san pham nay c kiem tra ky lng theo yeu cau bat buoc trc khi
xuat xng.
- Nh tat ca cac loai vacxin, co the xay ra cac thao tac sai oi vi san pham bao gom bao
quan khong ung cach, nhiet o khong bao am trong qua trnh bao quan.
- Tiem khong u lieu va dung vaxin khong ung cach, dung vacxin khi dch bung phat,
ong vat b nhiem trc khi mien dch kp tao ra co the dan en that bai trong tiem phong
mac du vacxin co chat lng tot.
- Cac yeu to stress ong vat a c tiem phong (thi tiet qua lanh, van chuyen ong
vat ng dai) dan en ap ng cua ong vat oi vi vacxin di mc toi u.
- Quan ly trai kem, nhiem ky sinh trung nang, ngo oc... cung anh hng ti qua trnh
tao mien dch ong vat tiem phong va lam cho vacxin tot tr nen khong hieu lc.
- Hiem khi xay ra trng hp ong vat co phan ng qua man sau khi tiem phong. Trong
trng hp xay ra co the cha bang nhng san pham khang histamine thong thng. ay
la hien tng t nhien thong thng, ch xay ra n le trong khi hang ngan con vat khac
tiem vacxin cung lo, cung thi iem eu bnh thng. Hn na, phan ng nay khong ch do
vacxin ma thng quan sat thay nhng trng hp khi s dung nhng che pham protein,
phan oan cua protein hoac chat gay d ng.
- Khong can thi gian ngng s dung vacxin trc khi giet tht hoac lay sa lam thc
pham. Vacxin khong gay anh hng en sc khoe con ngi.
50B ang Dung - quan I - TP. Ho Ch Minh - Tel: (84.8) 38245077, Fax: (84.8) 38245077.
8. VACXIN POSI - FMD (MONOVALENT)
ac tnh:
- Vacxin vo hoat, dang dau, n gia phong benh L mom long mong.
42
- Virus c nuoi cay tren moi trng te bao BHK.
- Chat vo hoat: Ethylenimine.
- Chat bo tr: Dau monatanide ISA 206.
- Chat bao quan: Thiomersol.
- Chat vo hoat cho BEI: Dung dch muoi thiosulphate.
Thanh phan:
Moi lieu vacxin gom co:
Ch nh: Dung tiem cho ln, trau, bo, be, de va cu e phong chong benh L mom
long mong cho ln, trau, bo, de va cu.
Hng dan s dung:
khi tiem.
- Vacxin c tiem sau bap va tiem di da nhng vung da sach, kho e tranh b
nhiem trung.
- Tiem phong lan au tien: 4 thang tuoi (trau, bo, de, cu)
- Tiem phong lan au tien: 2 thang tuoi (ln)
- Tiem phong tang cng: 9 thang sau mui au tien (trau, bo, de, cu).
- Tiem nhac lai: c sau 12 thang (trau, bo, de, cu)
- Tiem nhac lai: c sau 6 thang (ln)
- Lieu dung: Trau, bo, be va ln: 2ml/con. Cu, de: 1ml/con
Chong ch nh: Khong
Mien dch: Mien dch keo dai trong 24 thang. Tuy nhien viec tiem phong hang nam van
c nhac lai tuy tnh hnh dch te a phng.
Chu y:
- POSI - FMD Monovalent a qua kiem nghiem trc khi a vao s dung.
- Trong cac moi trng va ieu kien khac nhau can tranh gay tap nhiem vi khuan moi
khi rut vacxin POSI-FMD Monovalent ra khoi lo.
Thi gian ch i: Khong
43
Trnh bay: Chai 30ml, chai 100ml, chai 200ml.
Bao quan: nhiet o 2-80C, tranh anh sang va ong a. e xa tam tay tre em.
Han dung: Ch nh tren nhan.
Nha san xuat: Cong ty Pfizer - VN, tang 7, phong 7.IB, 364 ng Cong Hoa, quan Tan
Bnh, TP. Ho Ch Minh.
Tel: (84.8) 38122464 Fax: (84.8) 38122712
9. VACXIN AFTOPOR
Thanh phan:
Khang nguyen: Virus L mom long mong vo hoat.
Typ O, A, C, Asia, SAT 1, SAT 2, SAT 3.
Moi lieu cha t nhat 3 DP50 cho moi hieu gia (xem tren nhan).
Chat bo tr: nhu dau kep (DOE): nc trong dau, tat ca nam trong nc.
Aftopor lu hanh Viet Nam c san xuat rieng cho VN, phu hp ieu kien dch te
mi gom cac loai sau:
- n gia typ O vi hai chung la O Manisa va O 3039.
- n gia typ A vi hai chung la A 22 va A Malayxia 97.
- Nh gia typ O + A vi bon chung: O Manisa va O 3039, A 22 va A Malayxia 97,
Asia shamir.
Ch nh: Phong benh L mom long mong cho ln va ong vat nhai lai.
Hng dan s dung:
- Tron dung dch thuoc that ky bang cach xoay tron chai thuoc trc khi s dung
khoang 20 lan.
- Tiem bap. Tot nhat la tiem co, ngay sau tai oi vi ln va co pha trc oi vi
ong vat nhai lai.
- Lieu dung: Khong ke tuoi tac va trong lng gia suc (xem nhan).
* Vung co nguy c nhiem benh L mom long mong thap:
- oi vi vat nuoi sinh ra t me khong tiem phong:
+ Ln, cu, de: tiem toan an luc 14 ngay tuoi, tiem mot mui. Neu thi gian nuoi
keo dai hn 6 thang th tiem mui th hai cach mui th nhat 4-5 tuan. Tiem nhac lai
6 thang mot lan.
- De, cu ln hn 1 nam tuoi, moi nam tiem nhac lai mot lan.
+ Be: tiem toan an luc 14 ngay tuoi sau o 4-5 tuan tuoi tiem mui th hai. Tiem
nhac lai 6 thang mot lan.
- oi vi vat nuoi sinh ra t me a tiem phong:
44
+ Ln, cu, de: tiem toan an luc 2,5 thang tuoi, tiem mot mui. Neu thi gian nuoi
keo dai hn 6 thang th tiem mui th hai cach mui th nhat 4-5 tuan. Tiem nhac lai
6 thang mot lan.
De, cu ln hn 1 nam tuoi, moi nam tiem nhac lai mot lan.
+ Be: tiem toan an luc 2,5 thang tuoi sau o 4-5 tuan tiem mui th hai. Tiem nhac
lai 6 thang mot lan.
* Vung co nguy c nhiem benh L mom long mong cao:
- oi vi vat nuoi sinh ra t me khong tiem phong:
+ Tiem toan an luc 14 ngay tuoi sau o 4-5 tuan tiem mui th hai.
+ Tiem nhac lai: C 4 thang tiem nhac lai mot lan cho ln va bo, c 6 thang mot lan
cho de, cu.
- oi vi vat nuoi sinh ra t me a tiem phong:
+ Tiem toan an luc 2 thang tuoi sau o 4-5 tuan tiem mui th hai.
+ Tiem nhac lai: C 4 thang mot lan cho ln va bo, 6 thang mot lan cho de, cu.
Chong ch nh: Khong co
Chu y:
- Ch tiem phong cho vat nuoi khoe manh. Thao tac can than oi vi gia suc mang thai.
- Bao quan vacxin trong ieu kien vo trung thong thng, khi a m nap lo, vacxin ch
c s dung trong vong 36 gi vi ieu kien phai c bao quan nhiet o t 20C en
80C va khong c am kim vao nut cao su nhieu lan.
Phan ng tai cho: Sau khi tiem phong co the phu nhe cho tiem va/hoac co the kem sot
nhe trong mot thi gian ngan. Rat hiem khi xay ra trng hp qua man v vacxin tinh khiet.
Bao quan: nhiet o t 2-80C, trong bong ram, khong c lam ong lanh.
Trnh bay: Chai 50ml - Afopor 50ml.
10. VACXIN VO HOAT L MOM LONG MONG
(Chung O (II) cua ln)
ac tnh:
- Vacxin at tieu chuan quoc te, a c kiem tra an toan va kiem tra hieu lc.
- Virus nuoi cay qua te bao BHK21.
- Vo hoat bang BEI.
- Nhu hoa kep bang dau khoang.
45
Thanh phan:
- Khang nguyen nc (140S > 1,2 g/ml)
- Nhu dch dau
- Khang sinh va chat kh trung
Ch nh:
- Phong benh LMLM ln do typ O gay ra
- Khong che, dap tat o dch
- Ngan chan, bao vay s lay lan cua o dch
Thi gian mien dch:
- Sau khi tiem 15 ngay san sinh mien dch.
- Sau 30 ngay ap ng mien dch (nang lc bao ho lieu 100 - 200MID - lieu gay benh
toi thieu).
- Mien dch keo dai 6 thang.
- Ln con sinh ra t me cha c tiem vacxin:
Lan 1: Luc 2-3 tuan tuoi
Lan 2: Sau 7-8 tuan tuoi
- Ln con sinh ra t me a c tiem vacxin va co u mien dch: tiem mui au khi ln
6-7 tuan tuoi.
- Ln hau b hay ln giong sinh san (ca ln c va ln nai): tiem mui au khi ln 6-7
tuan tuoi.
- Ln cha: Sau khi tiem 4-6 tuan th mien dch truyen qua sa cho con, 6 thang th tiem
nhac lai mot lan.
Lieu lng: Tiem bap tht sau goc tai trai cua ln, lieu:
- Ln di 25kg: 1ml/con
- Ln tren 25kg: 2ml/con
Chu y: Vacxin co the tiem vung ang co dch, khu co nguy c lan tran dch va phong
cho nhng vung an toan. Phai tiem khu an toan trc, sau o la khu ang b e doa va cuoi
cung mi tiem en khu b dch.
Bao quan: Bao quan vacxin nhiet o 4-80C, ni kho, tranh anh sang trc tiep
Han dung: 12 thang
Nha phan phoi: Cong ty CP Thuoc va Vat t thu y (Hanvet),
88 Trng Chinh - ong a - Ha Noi, Tel: 04.8691156.
46
11. VACXIN PORCILIS BEGONIA
(Vacxin anh dau phong benh gia dai ln)
Mo ta: Porcilis AD Begonia la vacxin anh dau song nhc oc ong kho. Moi lieu
cha t nhat 1055 TCID50 virus Aujeszky dong Begonia nhc oc a cat bo hai oan gen tk
va gE. Muc ch la lam cho dong virus vacxin on nh va khong xay ra hien tng nhiem
ngam tren ln. Loai bo gen gE giup phan biet c ln tiem phong va ln nhiem benh. Pha
vacxin vi nc pha Diluvac Forte e tang cng va keo dai ap ng mien dch.
Ch nh: Tao mien dch chu ong cho ln phong benh gia dai (Aujesky).
Ln tht:
- Neu ln con khong co khang the me truyen, tiem lan au sm, luc 1 tuan tuoi. Mien
dch tao ra sau mot lan tiem phong se duy tr en cuoi giai oan nuoi tht, hay t nhat en
6 thang tuoi.
- Neu ln con sinh ra co khang the me truyen th co the tiem phong cho ln con mot lieu
vao 14 tuan tuoi. Mien dch tao ra se bao ho cho ln en het giai oan nuoi tht. Khi co
nguy c nhiem benh sm, ln con co khang the me truyen cac mc o khac nhau co the
tiem phong luc 10 tuan tuoi va lap lai luc 14 tuan tuoi.
Ln giong:
Tiem phong can ban nh ln tht. Sau o tiem nhac lai 4 thang mot lan (3 lan moi nam).
Tiem cho toan an.
Hng dan s dung:
- Pha vacxin vao lo nc pha Diluvac Forte hoac Unisolve i kem, moi lieu 2ml cha t
nhat 1055 TCID50 virus Aujeszky dong Begonia dung cho moi la tuoi.
- Tiem bap tht.
Trnh bay: Lo 10 lieu hoac 50 lieu.
Bao quan: Vacxin bao quan lanh t 2-80C, tranh anh sang. Lo nc pha c bao quan
nhiet o phong (15-250C).
Chu y:
- Ch tiem phong cho ln khoe manh
- S dung ngay lo vacxin sau khi pha
- Dung dung cu tiem phong vo trung
Nha san xuat:
Cong ty INTERVET - VIETNAM, A PART OF SCHRING PLOUGH CORPORATION,
50B ang Dung, quan 1 - TP. Ho Ch Minh- Tel: (84.8) 38245077, Fax: (84.8) 38245077.
47
12. VACXIN AUSKIPRA - NG
ac tnh:
- La vacxin song
- Virus Aujesky chung gE (-), dang vien ong kho dung e tiem.
Nhng phat hien gan ay ve DNA cua virus Aujesky khi s dung cac enzyme ac thu a
chng minh rang hau het cac virus a b lam yeu co s thieu oan Us cua DNA. Tai vung
nay glycoprotein E (thng co mat hau het cac virus oc lc manh hoac virus a b lam
yeu) c ma hoa.
S dung phan ng ELISA vi khang the n dong co the phan biet cac ong vat a c
chung vacxin gE (-) vi cac ong vat b nhiem virus oc lc manh bi v chung co khang
the chong lai gE glycoprotein. ieu nay giup chung ta loai bo ngay t au toan bo cac ln
a b nhiem benh trc khi tien hanh chng trnh tieu diet mam benh.
Co the at c hieu qua bao ho an ln t 48 gi sau khi tiem vacxin mac du ham
lng khang the toi a at c sau 7 ngay tiem vacxin.
Thanh phan (trong 1 lieu): Virus Aujeszky gE (-) chung Bartha K61 105.5 TCID50.
Ch nh: Phong benh gia dai ln
Hng dan s dung:
- Tiem bap co hoac nho mui
- Tiem bap tht: s dung nc pha o hoac nc pha trang.
- Nho mui: s dung nc pha o, nho 1ml cho mot lo mui.
- Lac ky cho en khi hoan nguyen hoan toan vien vacxin ong kho trc khi s dung.
- Sau khi hoan nguyen, vacxin phai s dung het trong 1 gi.
- Lieu dung: 2ml/ln, ap dung t 10 tuan tuoi tr i, khong ke gii tnh, trong lng.
- Ln tht: Mot lieu, tiem bap, luc 12-13 tuan tuoi. Vung co dch, tiem sm hn, 10-11
tuan tuoi va tiem lap lai 13-14 tuan tuoi.
- Ln nai va c: Tiem 2 lieu cach nhau 3-4 tuan cho ln giong khi a vao chuong
giong hoac cho cac ln giong ma trc o cha c tiem vacxin lan nao. Sau o c 4
thang tiem nhac lai mot lan hoac tiem nhac lai 4-6 tuan trc moi la e.
- Khi co dch, tiem mot lieu cho toan an (ln nai, c va ln con).
Bao quan: 2-80C, tranh anh sang
Trnh bay:
- Hop 10 lo 10ds (W)
- Hop 50 ds (W) s dung di s hng dan cua bac sy thu y.
Nha phan phoi: Cong ty Thuoc thu y Xanh (GREENVET),
48
186 Trng Chinh, ong a, Ha Noi. Tel: (84.4) 35659240, Fax: (84.4) 35659593.
13. VACXIN SUVAXYN AUJESZKY NIA3 - 783
(Vacxin virus nhc oc phong benh gia dai tren ln)
ac tnh:
- Suvaxyn Herdfen PRV la mot vacxin vo hoat tang cng chat phu gia co hieu qua
ngan nga benh ly lam sang tren ln. Nai t va nai ra c tiem phong co the truyen khang
the me sang con, lam giam t vong do benh gia dai gay ra.
- Suvaxyn Aujeszky NIA3 783 la mot vacxin song, ong kho cha virus benh Aujesky
dong NIA3 783 dung tiem phong cho ln giup chong lai benh gia dai (Aujeszkys).
- ac tnh TK (am tnh thymidinekinase) cua Suvaxyn Aujeszky NIA3 783 giup gia tang
tnh an toan cua dong vacxin.
- ac tnh gl (am tnh glycoprotein 1) do virus vacxin tao ra giup phan biet c gia
khang the sinh ra t viec tiem phong vi khang the co c t viec nhiem virus benh gia
dai t moi trng. ac tnh sinh mien dch cua vacxin c gia tang do them vao ta dc
dang nhu tng dau trong nc (oil in water).
- ieu nay co hieu qua ac biet trong viec ngan chan s bai thai cua virus ra moi trng
sau khi b nhiem virus t nhien va co tam quan trong rat ln trong qua trnh xay dng
chng trnh loai tr triet e mam benh trong trai.
Ch nh: Tiem phong cho ln giup chong lai benh gia dai.
Hng dan s dung:
- Lieu lng: 1 lieu = 2ml.
- Vacxin ong kho phai c pha vi nc pha cua Aujeszky hoac trong nhu tng
Suvaxyn o/w.
- Vacxin a pha phai tiem phong theo ng tiem bap tht phan co pha sau tai.
- Ln tht: Tiem mot lieu cho ln nuoi tht vao thi iem bat au vo beo.
- Kha nang cao nhat ngan chan s bai thai virus sau khi ln nhiem benh t moi trng t
nhien la khi ta tiem phong cho ln 2 lan va khoang cach gia 2 lan tiem la 3-4 tuan.
- an ln giong: Tiem phong lan th nhat luc ln c 10-14 tuan tuoi va tiem phong
lan th hai 3-4 tuan sau o. Tiem nhac lai trc khi phoi giong lan th nhat oi vi nai t
lam giong trong trng hp ap dung chng trnh loai tr triet e virus moi trng.
- Nai ra: Tiem phong trong khoang 3-6 tuan trc khi e. Trong trng hp ap dung
chng trnh loai tr triet e virus moi trng, nai ra co the c tiem phong c sau moi 4
thang cho toan an.
Chong ch nh: Ch tiem cho ln khoe manh. Ngan nga stress trc, trong va sau khi tiem.
Canh bao: Phan ng phu
- Vacxin cha chat phu gia do o phan ng tam thi co the xay ra tai v tr tiem.
49
- Bat ky vacxin nao cung co the co phan ng qua man, s dung Epinephrine (Adrenaline)
co tron vi mot thuoc thuoc nhom Corticosteroid tac dung nhanh nh la mot thuoc giai oc.
Bao quan: 2-80C
Trnh bay: Lo 50 lieu
Han s dung: Ghi tren bao b
Nha phan phoi: Cong ty CP Phat trien Cong nghe Nong thon (RTD),
Khu CN An Khanh - Hoai c - Ha Noi, Tel: (84.4) 0343650574.
14. VACXIN SUVAXYN I AUJESZKY O/W
(Vacxin chet nga benh gia dai (Aujezky) tren ln)
- Tiem bap tht hoac di da vi lieu 2ml/ln.
- an giong:
+ Nai t va nai ra tiem luc 6-8 tuan trc khi e.
+ Ln c giong: tiem nhac lai hang nam.
+ Ln mi mua ve nuoi cach ly 30 ngay va tiem phong vao khoang 2 tuan le trc
khi nhap an.
- Ln con:
+ Tiem phong luc 14 ngay tuoi cho nhng ln con ma cha me chung cha b nhiem
benh va cha c tiem phong vi lieu 2ml/con u sc bao ho ti khi ban tht.
+ Tiem phong lan th nhat luc 5-6 tuan, lan 2 luc 10-12 tuan cho nhng ln con ma
cha me chung a b nhiem benh va a c tiem phong.
Chu y:
- Bao quan nhiet o 2-70C, tranh ong a.
- Khong tiem cho ln trong vong 21 ngay trc khi giet mo.
- Lac ky lo vacxin trc khi s dung.
- S dung het vacxin khi a m lo, huy toan bo lo va vacxin tha.
- Neu co phan ng bat li xay ra, s dung Epinephrine.
Trnh bay: Lo 10 lieu/20ml; lo 50 lieu/100ml
Khu CN An Khanh - Hoai c - Ha Noi . Tel: (84.4) 0343650574
15. VACXIN AMERVAC - PRRS VACXIN
(Vacxin phong hoi chng roi loan ho hap va sinh san tren ln (PRRS)
50
ac tnh:
- Trong 1 lieu (2ml)
- Virus PRRS song, chung VP 046 BIS 103.5 TCID50
- VP 046 BIS co kha nang bao ho tat ca cac chung chau Au khac va co kha nang bao
ho cheo vi chung chau My.
Mot van e het sc quan trong la AMERVAC-PRRS chung VP 046 la chung an toan
nhat trong cac chung chau Au va hoan toan khong gay hoan nguyen oc lc.
Do s xuat hien cua virus gay ra hoi chng loan sinh san va ho hap tren ln (PRRS)
phc hp benh ho hap gia tang ang ke do anh hng cua no tren tieu the ai thc bao.
ieu nay c thay ro ln sau cai sa cung nh tren ln giai oan vo beo (benh viem
phoi mang phoi, benh Aujeszky, benh Mycoplasma) ket qua lam tang ang ke so ln
chet trong trai khi so sanh vi so ln chet trc khi xuat hien PRRS.
V nhng ly do tren, LABORATORIOS HIPPRA, S.A a san xuat ra vacxin Amervac -
PRRS co cha chung virus nhc oc VP 046 BIS chong lai benh nay nham gop phan vao
viec phong nga PRRS va lam giam tien trnh viem phoi do tac ong cua hang loat virus,
vi khuan c hoi trong phc hp benh ng ho hap tren ln.
Tnh an toan:
- Khong tr lai ong lc
- Khong gay sot cho ln khi tiem
- Khong gay phan ng phu khi tiem
- Khong bai thai virus vacxin ra moi trng
- Co the tiem tren ln mang thai, virus vacxin khong truyen qua nhau thai
Hieu lc:
- Bao ho tren nai: Bao ho ln nai chong lai PRRS lam giam ty le e non, say thai, chet
thai va truyen khang the bao ho trong thi gian con bu.
- Bao ho tren con: Bao ho PRRS giam ty le viem nhiem ho hap th phat.
- Bao ho cheo: Vacxin song nhc oc chung VP 046 BIS la cong cu an toan va hieu
qua e kiem soat benh tai xanh ca chung chau Au lan chung chau My (a c kiem chng
bi th nghiem cua Thanawongnwech, et al. 2006 IP VS 2006).
Thi gian bao ho:
- Khang the bao ho ngay th 11 sau khi tiem la 80%.
- Ngay th 32 sau khi tiem: khang the bao ho at 100% va keo dai en ngay th 125.
* Trong trai co dau hieu benh cap tnh tren ln nai:
Tiem ong loat tren ln nai 2 lan, cach nhau 1 thang. Sau o, co the theo mot trong hai
chng trnh sau:
51
+ Tiem 1 lieu vacxin song 12-15 ngay sau khi sinh.
+ Mot lieu vacxin: 2ml cho mot ln khong ke gii tnh, tuoi va trong lng ln.
* Trong trng hp tiem phong thng ky
- Ln nai t va c giong hau b can tiem 1 lieu vacxin song 5-6 tuan trc khi phoi lan au.
- Ln nai tiem 1 lieu vacxin song 12-15 ngay sau khi e.
- Ln c giong, tiem 6 thang mot lan.
* Tiem phong ln con:
Mot thang sau khi tiem toan an nai, bat au tiem cho ln con 1 lieu vacxin song luc
3-4 tuan tuoi.
186 Trng Chinh, ong a, Ha Noi - Tel: (84.4) 35659240, Fax: (84.4) 35659593
16. VACXIN BSL PS100
(Vacxin song dang ong kho phong nga hoi chng roi loan sinh san tren ln nai va
ho hap tren ln con (PRRS)
ac tnh:
- Vacxin PRRS nhc oc ong kho the he mi co nguon goc t chung JKL 100 thuoc
dong My (American Strain). Mot lieu vacxin cha t nhat 105.0 TCID 50.
- BSL PS100 co o an toan rat cao. Th nghiem a chng minh BSL PS100 an toan du
tiem cao gap 20 lieu.
Hieu qua cua vacxin:
Thc nghiem a chng minh tren lo ln co s dung vacxin BSL PS 100 cho thay tren ln
con bu me, ty le t vong rat thap (0%) so vi lo oi chng khong s dung vacxin la (7%).
Va hieu qua tren ln tht, tang trong them 15% vi ln khong tiem.
Mien nhiem:
Vacxin BSL PS100 kch hoat he thong mien dch nhanh chong va keo dai. Mot tuan sau
khi tiem phong th ham lng khang the trong mau at mc co kha nang bao ho va thi
gian mien dch keo dai khoang 16 tuan.
- Tiem bap tht 2ml/lieu
- Nai t nai nuoi con: Tiem trc khi cai sa hoac trc luc phoi giong.
- Ln c: Tiem luc 18 tuan tuoi va tiem nhac lai hang nam.
- Ln con ( trai khong co dch): Tiem mot lan luc 3 tuan tuoi. Tiem lan 2 luc 6 tuan tuoi.
- Neu trai ang co dch: Tiem phong ngay cho nai mang thai di 70 ngay cua thai ky.
- Lu y: Ch c pha vacxin vi nc pha cua chnh vacxin
52
Trnh bay: Lo 10 lieu, 25 lieu va 50 lieu.
Nha phan phoi: Cong ty CP Phat trien Cong nghe Nong thon (RTD).
17. VACXIN BSK - PS 100
(Vacxin vo hoat phong nga hoi chng roi loan sinh san tren ln nai va ho hap tren
ln con (PRRS)
ac tnh:
- Vacxin BSK-PS100 la vacxin vo hoat cha chung virus benh PRRS dong chau Au (E strain).
- Mot lieu vacxin cha t nhat 107.5 TCID50.
- BSK-PS100 co o an toan rat cao. Th nghiem a chng minh BSK-PS100 an toan du
tiem cao gap 10 lieu. Vacxin an toan oi vi ln mang thai.
- Thc nghiem a chng minh tren lo ln co s dung vacxin BSK - PS100 cho ty le song
sot cua ln s sinh cao hn 6,4%; ty le ln s sinh chet thap hn 3,7%; ty le thai chet
lu va thai go thap hn 3,6%; ty le ln con cai sa cao hn 9,1% so vi lo ln nai khong
chung vacxin.
- Tiem phong vacxin tren nai giup nang cao so ln tren o va ty le ln con cai sa ong
thi lam giam ty le thai chet lu va thai go.
Mien nhiem:
Vacxin BSL PS100 kch hoat he thong mien dch nhanh chong va keo dai. Mot tuan sau
khi tiem phong th ham lng khang the trong mau at mc co kha nang bao ho va thi
gian mien dch keo dai khoang 16 tuan.
- Tiem bap tht 2ml/lieu
- Nai t nai nuoi con: Tiem trc khi cai sa hoac trc luc phoi giong.
- Ln c: Tiem luc 18 tuan tuoi va tiem nhac lai hang nam.
- Ln con ( trai khong co dch): Tiem mot lan luc 3 tuan tuoi. Tiem lan 2 luc 6 tuan tuoi.
- Neu trai ang co dch: Tiem phong ngay cho nai mang thai di 70 ngay cua thai ky.
- Lu y: Ch c pha vacxin vi nc pha cua chnh vacxin
Trnh bay: Lo 10 lieu, 25 lieu va 50 lieu.
Khu CN An Khanh - Hoai c - Ha Noi, Tel: (84.4) 0343650574
53
18. VACXIN HOI CHNG HO HAP, SINH SAN LN (PRRS)
ac tnh:
- Mo ta: Vacxin chet, nhu dau
- Virus PRRS chung NVDC-JXA 1, moi ml vacxin cha khong thap hn 106 TCID50
trc bat hoat
- Chat bat hoat: Formaldehyde
- Chat bo tr: Dau khoang
Hng dan s dung:
- Vacxin dung phong benh Hoi chng ho hap, sinh san cho ln khoe manh.
- Tiem bap tht sau tai
- Lieu dung: 2ml/con cho ln 3 tuan tuoi
4ml/con cho ln nai trc khi sinh san
4ml/con cho c giong 6 thang 1 lan
Chu y:
- Lo vacxin phai c lac ky trc khi dung.
- a lo vacxin ve nhiet o bnh thng trc khi s dung.
- Khong dung lo vacxin b nt v.
- Sau khi m, lo vacxin dung trong ngay.
- Bm tiem va kim tiem phai c tiet trung trc khi s dung, thay kim thng xuyen.
- Dung than trong oi vi ln ang mang thai.
Chong ch nh: Khong dung cho ln ang b benh hoac om yeu.
Thi gian ngng thuoc: 21 ngay trc khi giet tht.
Bao quan:
- Nhiet o bao quan t 2-80C.
- Khong c e vacxin vao ngan ong a.
- Trong qua trnh van chuyen phai gi vng trong thung xop a lanh (hoac a kho),
tranh nong va anh sang trc tiep.
Trnh bay: Chai 10 lieu, 20 lieu, 50 lieu
Han dung: 18 thang ke t ngay san xuat khi bao quan 20C - 80C.
Nha san xuat:
Chengdu Medical Equipment and Pharmaceutical Factory of Animal Husbandry
Industry Co, Ltd. Trung Quoc.
54
Nhap khau va phan phoi:
Cong ty TNHH Mot thanh vien thuoc thu y Trung ng (NAVETCO).
- a c Trung tam chan oan Thu y Trung ng (vi s cho phep cua Cuc Thu y) tien
hanh khao nghiem va cho ket qua tot tai trai ln Nguyen Quy Tam, xa Tan Hoi, huyen
an Phng, Ha Noi.
- a c phep s dung th iem tai mot so huyen cua 4 tnh Thai Bnh, Ninh Bnh, Nam
nh, Ha Noi (tong cong 13.011 con).
19. VACXIN PARVOERYSIN- INJ
ac tnh:
Vacxin vo hoat cha:
- Parvovirus chung S-27 toi thieu co 512HA- n v ngng ket hong cau.
- Cha t nhat 2.1010 Erysipelothrix rhusiopathiae typ 3, 2 va 1.
- Vacxin PARVOERYSIN-INJ la vacxin vo hoat dang dung dch.
Ch nh:
PARVOERYSIN-INJ c ch nh phong benh Parvovirus va benh ong dau cho ln
nai, hau b va c giong.
PARVOERYSIN-INJ phong benh kho thai va say thai do Parvovirus va benh ong dau ln.
Hng dan s dung:
- Lac ky trc khi dung.
- Tiem bap, lieu chung: 2ml/1 lieu.
- Vi ln hau b: Tiem 1 lieu trc khi phoi giong 3-4 tuan.
- Vi nai sinh san: Tiem 1 lieu trc khi phoi giong 2-3 tuan.
- Vi ln c giong: Tiem 1 lieu trc lan phoi giong au tien 2-4 tuan, nhac lai 1 lieu
sau moi 6 thang.
Trnh bay: Chai 5 lieu, 10 lieu, 50 lieu.
Bao quan: nhiet o 2-80C va tranh anh sang mat tri.
Han s dung: 24 thang ke t ngay san xuat
Nha san xuat: BIOVETA, a.s - Komenskeho 212 683 23 Ivanovice na Hane Czech Republic.
186 Trng Chinh, ong a, Ha Noi. Tel: (84.4) 35659240, Fax: (84.4) 35659593.
20. VACXIN PORCILIS PARVO
(Vacxin vo hoat phong benh thai go do virus parvo gay ra)
ac tnh:
55
Porcilis Parvo la vacxin vo hoat phong benh thai go do virus Parvo gay ra tren ln.
Khang nguyen virus Parvo trong chat bo tr Diluvac Forte.
Ch nh:
Tiem phong cho ln nai va ln hau b e bao ho phoi va bao thai chong lai virus Parvo.
- Ln hau b: Tiem phong can ban hai lieu vacxin vao 8 va 2 tuan trc khi phoi giong.
- Ln nai: Tiem mot lieu trc khi phoi giong t nhat 2 tuan.
- Lieu lng: 2ml tiem bap tht.
Trnh bay: Lo 20ml/10 lieu, 50ml/25 lieu va 100ml/50 lieu.
Bao quan: nhiet o 2-80C, tranh ong a va tranh anh sang.
Chu y:
- e vacxin am len at nhiet o phong (15-250C) trc khi s dung.
Nha san xuat:
50B ang Dung - quan 1 - TP. Ho Ch Minh. Tel: (84.8) 38245077, Fax: (84.8) 38245077
21. VACXIN PARVO SHIELD L5E
(Vacxin parvovirus chet - vacxin vi trung vo hoat phong nga cac benh say thai truyen
nhiem, benh ong dau va mot so vi khuan khac)
ac tnh:
- Vacxin Parvo L5E c ket hp t 7 vi sinh vat bao gom Parvovirus, Erysipelothrix va
5 chung cua Leptospira gom: L.canicola; L.gryppotyphosa; L.hardjo; Licterohaemorrhagiae;
L.pomona.
- Parvo Shield L5E c ket hp t 7 vi sinh vat khac nhau nhng khong co s giao thoa
gia cac thanh phan khac nhau cua vacxin.
- Parvo Shield L5E c lam bat hoat trong mot quy trnh san xuat ac biet co tnh an
toan, hoan hao va gi khang nguyen toi a.
- Parvo Shield L5E c bo tr vi hydroxide nhom co o tinh khiet cao, hieu lc toi
a va de tiem.
- Parvo Shield L5E co cha Amphotericin B, Penicillin, Streptomycin va Thimerosal
lam chat bao quan.
56
Hng dan s dung:
- Tiem bap tht lieu 5ml/con cho ln hau b 4-6 tuan trc khi phoi giong, tiem nhac lai
3-4 tuan sau o.
- Tiem mot lieu trc moi lan phoi giong tiep theo.
- Tiem cho ln c giong 6 thang mot lan.
Chu y:
- Bao quan nhiet o 2-70C, tranh ong a.
- Khong tiem cho ln trong vong 21 ngay trc khi giet mo.
- S dung het vacxin khi a m lo, huy toan bo lo va vacxin tha.
- Phan ng bat li t khi xay ra. Neu co, s dung Adrenaline.
- Ch tiem vacxin cho vat nuoi khoe manh.
Trnh bay: Lo 50ml/10 lieu, 100ml/20 lieu, 250ml/50 lieu.
22. CIRCUMVENT PCV
ac tnh:
- Vacxin vo hoat
- Moi lieu 2ml cha:
Khang nguyen PCV 1.0 RP.
Ta chat: Gentamycin 60g
Chat bao quan: Thiomersal
Chat bo tr: Microsol Diluvac Forte
- ac tnh dc lc hoc: thanh phan hoat chat sinh mien dch la khang nguyen PCV 1.0RP.
- ac tnh dc ong hoc: kch thch ln tao khang the chong lai Porcine Cireovirus type 2.
Ch nh:
- Dung e phong nga hoi chng coi coc tren ln do PCV2 va ngan nga s bai thai
virus. Trong trng hp ln b nhiem tre hoac khang the me truyen thap, ch tiem 1 lieu
(2ml) cho ln t 3 tuan tuoi tr len. Tiem bap tht vao vung pha sau tai.
Trong trng hp ln b nhiem sm hoac khang the me truyen cao, khuyen cao ap dung
lch tiem phong 2 mui: mui 1 vao 3-5 ngay tuoi (lieu 2ml), mui 2 sau mui 1 t 2-3 tuan (lieu
2ml). Tiem bap tht vung pha sau tai.
57
- Lieu dung: Tiem bap tht, lieu 2ml.
Chu y:
- Trc kh s dung, e vacxin am len bang nhiet o phong (15-250C). S dung bm va
kim tiem vo trung.
- Khong khuyen cao pha tron vi cac san pham thuoc thu y khac.
- Tac dung khong mong muon:
Than nhiet co the tang nhe 1-2 ngay sau khi tiem. Mot so nho ln con co the giam an
hoac l . Mot so t trng hp co the sng nhe tai cho tiem. Mot so trng hp qua man
cam co the xay ra nhng se t het sau vai phut ieu tr.
- San pham nay co cha dau khoang. Trong trng hp tiem nham vao tay co the dan
en au va sng. Trong mot so trng hp neu tiem vao ngon tay hoac khp co the dan en
phai cat bo phan b h hoai neu cong tac s cu luc au khong ung mc.
Can rat than trong khi dung thuoc va tm ngay s tr giup t bac s neu tai nan xay ra.
Thi han ngng s dung thuoc: Khong.
Han s dung: 2 nam tnh t ngay san xuat
Bao quan: nhiet o t 2-80C. Sau khi am kim ch s dung trong vong 8 tieng.
Trnh bay: Lo nha 100ml (50 lieu); 200ml (100 lieu); 500ml (250 lieu). Lo c ay
bi nap cao su co vo nhom boc ngoai.
Cong ty INTERVET - VIETNAM, A PART OF SCHERING PLOUGH CORPORATION
50B ang Dung - quan I - TP. Ho Ch Minh. Tel: (84.8) 38245077, Fax: (84.8) 38245077
23. VACXIN PORCILIS BPM
(Vacxin a gia phong nga phc hp ho hap tren ln)
ac tnh:
Porcilis BPM la vacxin vo hoat phong benh viem phoi a phng, tu huyet trung va
viem teo mui truyen nhiem tren ln gay nen bi:
- Mycoplasma hyopneumoniae
- Pasteurella multocida typ A
- Pasteurella multocida typ D
- Bordetella bronchiseptica
Ch nh:
Dung e tiem phong tao mien dch cho ln chong lai benh viem phoi a phng, tu
huyet trung va benh viem teo mui truyen nhiem.
58
- Ln con: Tiem lan au luc 5-7 ngay tuoi, tiem lan hai luc 23-28 ngay tuoi.
Chng trnh thay the: Tiem lan au luc cai sa, tiem lan hai sau lan au 3 tuan.
- Ln nai va hau b: Tiem hai lan vao 5 tuan va 2 tuan trc khi sinh, lan mang thai tiep
theo ch can tiem mot lan vao 2-3 tuan trc khi sinh.
- Ln c giong: Tiem moi nam mot lan.
Lieu lng va cach dung: Tiem bap tht
- Ln con: 1ml/con
- Ln trng thanh: 2ml/con
Trnh bay: Lo 100ml
Bao quan: 2-80C, tranh ong a va tranh anh sang.
Chu y:
- S dung ngay lo vacxin sau khi m nap.
50B ang Dung - quan I - TP. Ho Ch Minh. Tel: (84.8) 38245077, Fax: (84.8) 38245077.
24. VACXIN M + PAC
(San pham cua Schering Plough - USA)
ac tnh:
Vacxin M + Pac la vacxin nhu dau, cha khang nguyen Mycoplasma hyopneumoniae.
Ch nh:
- M + Pac c ch nh phong hoi chng ho th tren ln.
- Vi chat phu gia ac biet, M + Pac lam tang tnh khang nguyen, tang kha nang phong
benh, giam ty le ho th giam cac ton thng phoi, keo dai thi gian mien dch
- ng tiem: Tiem bap
- Chng trnh tiem chung 2 lan: lieu 1ml/con. Tiem 1 lan vao 7-10 ngay tuoi, tiem nhac
lai sau 2 tuan vi nai sinh san
59
- Chng trnh tiem chung 1 lan: lieu 2ml/con. Tiem 1 lan duy nhat vao 4 tuan tuoi hoac
ln hn.
Trnh bay: Chai 50 lieu, 10 lieu
Bao quan: 2-80C, tranh anh sang mat tri.
Chu y:
- Lac ky lo vacxin trc khi s dung
- S dung ngay lo vacxin sau khi m nap
186 Trng Chinh, ong a, Ha Noi. Tel: (84.4) 35659240, Fax: (84.4) 35659593
25. VACXIN MYCO SHIELDTM
(Vacxin chet nga benh viem phoi ln do Mycoplasma hyopneumoniae)
ac tnh:
- Myco ShieldTM la vacxin chet cha khang nguyen khuan vo hoat Mycoplasma
hyopneumoniae. Ngoai ra con cha Penicillin va Thimerosal dung lam chat bao quan.
- Myco ShieldTM la mot vacxin phan t, ch s dung phan khang nguyen e san xuat
vacxin v the rat an toan, tao ra mien dch cao. Nhng th nghiem tren thc a cho thay,
tren nhng con ln c tiem vacxin hoan toan khong b nhiem khi cho tiep xuc trc tiep
vi mam benh.
- Tren nhng ln c tiem vacxin benh tch phoi se giam i 5-8 lan.
- thi iem 155 ngay tuoi tren nhng con ln c tiem vacxin co tang trong cao hn
nhng con khong tiem la 6,8kg/con.
Lieu lng va cach s dung: Lieu 1ml, tiem bap tht cho ln con luc 2 tuan tuoi hoac
ln hn, tiem lai 2 tuan sau o.
Bao quan: 2-70C, tranh ong a, tranh anh sang trc tiep.
Thi gian ngng thuoc: Khong c giet mo trong khoang 21 ngay sau khi tiem vacxin
Chu y:
- S dung het vacxin khi a m lo
- Ch tiem vacxin cho ln khoe manh.
- Phan ng qua man co the xay ra. ieu tr bang Epinephrine
Trnh bay: Lo 100ml/100 lieu
60
26. VACXIN PORCILIS M HYO
(Vacxin the he mi phong nga benh viem phoi a phng do Mycoplasma)
ac tnh:
- Porcilis M Hyo la vacxin cha vi khuan Mycoplasma hyopneumoniae dong 11 vo hoat
phong benh viem phoi a phng tren ln gay nen bi Mycoplasma hyopneumoniae.
- Moi lieu vacxin 2ml co cha Mycoplasma hyopneumoniae dong 11 vo hoat > 7,0 log2
hieu gia khang the (hieu gia khang the trung bnh at c sau khi tiem chuot vi lieu bang
1/20 lieu dung cho ln).
- Chat bo tr: Diluvac Forte.
Ch nh: Phong benh viem phoi a phng do Mycoplasma hyopneumoniae gay nen
ln.
Ln con tiem hai lieu vao 5-7 ngay tuoi va 23-28 ngay tuoi.
Hoac ap dung chng trnh thay the: tiem lan mot luc cai sa va tiem nhac lai 3 tuan
sau o.
Lieu lng va cach s dung: Ln con tiem lieu 2ml/con, tiem bap tht.
Trnh bay : Lo vacxin 10, 25, 50 va 100 lieu.
Chu y:
- e vacxin am len at nhiet o 15-250C trc khi s dung.
- Lac ky lo vacxin sau khi m nap
Cong ty INTERVET - VIETNAM, A PART OF SCH ERING PLOUGH CORPORATION
27. VACXIN ONG DAU LN KEO PHEN
ac tnh:
- Vacxin chet c san xuat t chung vi khuan ong dau ln co tng ong khang
nguyen vi chung gay benh cho ln nc ta, diet bang formol, co chat bo tr la keo phen.
61
- Mot ml cha 10 ty vi khuan.
- Khi tiem vacxin t khi xay ra cac phan ng cuc bo hay toan than.
- Sau khi s dung vacxin 2 tuan, ln co mien dch va mien dch tot, on nh, keo dai 9
en 12 thang.
- Vacxin e lang, chia 2 lp, lp di lang la keo phen trang uc va lp tren co mau
vang trong.
Hng dan s dung:
- Dung e tiem phong benh ong dau ln cho ln khoe manh, t 45 ngay tuoi tr len.
- Moi nam can tiem cho ln t 1 en 2 lan (6 thang mot lan).
- Tiem vao di da sau tai hoac di da trong ui.
- Trc khi tiem phai lac eu lo thuoc.
- Lo thuoc a dung ch s dung trong 1 ngay.
- Lieu tiem: + Moi ln con di 3 thang dung 2ml.
+ Moi ln t 4 thang tr len dung 3ml.
Bao quan:
- Gi trong ieu kien lanh 100C bao quan c 9 thang va trong ieu kien nhiet o bnh
thng c 5-6 thang.
- Tranh e ni nong am co anh sang mat tri.
Trnh bay: Lo 50ml, 100ml.
29 Nguyen nh Chieu, quan I, TP. Ho Ch Minh. T: (8408) 3.8225063
28. VACXIN ONG DAU LN II (VR2)
ac tnh:
- Vacxin nhc oc che bang vi khuan ong dau ln chung VR2 (Rumani). Moi 1 ml
cha 10 ty vi khuan.
- Vacxin an toan khong gay phan ng cho ln cac la tuoi.
- Sau tiem 2 lan, ln co mien dch va mien dch keo dai 8-12 thang.
Hng dan s dung:
- Vacxin dung e tiem phong dch ong dau cho ln khoe manh t 2 thang tuoi tr len.
- Trc khi s dung lac eu lo thuoc.
- Dung cu, ong tiem khong c ra bang thuoc sat trung va khang sinh, ma ch vo trung
bang luoc.
62
- Tiem vao di da sau tai hoac di da trong ui.
- Lieu tiem: Tiem cho moi ln 1-2 ml.
Bao quan:
- Vacxin gi ni ram mat, t 40C en 100C bao quan c 9 thang. Neu e nhiet o
thng c 4 thang.
- Khong e trong lanh am.
- Tranh anh sang mat tri va ni nong am.
- Lo thuoc a m ch s dung trong 1 ngay.
Trnh bay: Lo 50 ml, 100ml
Chi nhanh:So 164 pho Phng Liet, Q. Thanh Xuan, Ha Noi - T: (84.4) 8691003
29. VACXIN TU HUYET TRUNG LN KEO PHEN
ac tnh:
- Vacxin vo hoat che bang chung vi khuan Pasteurella multocida (FgHc) co tnh ong
khang nguyen vi chung gay benh, c giet chet bang formol, co chat bo tr la keo phen.
Moi ml co cha 10 ty vi khuan.
- Khi e lang, vacxin chia lam 2 lp, lp keo phen trang ay, tren co lp nc trong
hi vang.
- Khi tiem di da, vacxin e lai mot u nho va se giam dan theo thi gian.
- Vacxin tao mien dch sau 2 tuan s dung va mien dch keo dai 6-9 thang.
Hng dan s dung:
- Vacxin dung e tiem phong benh tu huyet trung cho ln khoe manh t 2 thang tr len.
- Sau khi tiem phai c ngi theo doi phan ng na ngay e kp thi x ly.
- V tr tiem: di da sau tai hay di da ui trong.
- Tiem vacxin cho ln moi nam 2 lan, thng tiem vao trc mua ma 1 thang.
- Lieu tiem: Moi ln tiem 2ml tat ca cac la tuoi. Vi ln con 2 thang tuoi co the dung
1ml. Nhng sau 3-4 tuan phai dung lieu bo sung 2ml.
Bao quan:
- Vacxin gi ni ram mat, tot nhat la nhiet o t 40C en 100C, co the gi c 9 thang.
- Khong e vacxin trong tu ong lanh.
Trnh bay: Lo 100 ml co 50 lieu, lo 50 ml co 25 lieu, lo 10 ml co 5 lieu
63
30. VACXIN PHONG BENH XOAN TRUNG (LEPTOSPIROSIS)
ac tnh:
- Vacxin c che t cac chung vi khuan Leptospira gay benh cho ln, a giet chet bang
Merthiolat 1%. o la cac chung: Leptospira pomona, L.mitis, L.autumnalis, L.autralis,
L.icterohaemorrhagia, L.bataviae, L.canicola.
- Vacxin co the co bo tr la phen chua hoac dang canh khuan n thuan.
- Vacxin khong gay cac phan ng phu.
- Sau khi tiem 2 tuan, ln co mien dch va mien dch keo dai 6-9 thang.
Hng dan s dung:
- Vacxin dung e tiem phong benh Letospirosis (benh ln nghe) cho ln khoe manh t
2 thang tuoi tr len.
- Tiem i da hai lan, cach nhau 7 ngay.
- Ln nghi mac benh th khong tiem.
- Lac nhe lo vacxin trc khi dung.
- Lieu tiem:
+ Ln t 15-50kg, lan 1: 2ml/con; lan 2: 3ml/con
+ Ln tren 50kg; lan 1: 3ml/con; lan 2: 5ml/con
Bao quan:
- Vacxin e ni ram mat, t 40C en 80C, bao quan c 6-9 thang.
Trnh bay: Lo 100ml, lo 50ml
31. VACXIN PORCILIS APP
(Vacxin vo hoat duy nhat phong tat ca cac typ Actinobacillus pleuropneumoniae gay
benh viem phoi - mang phoi tren ln)
ac tnh:
- Porcilis App la vacxin vo hoat cha protein mang ngoai te bao va ba giai oc to ApxI,
Apx II, ApxIII cua vi khuan Actinobacillus pleuropneumoniae, co kha nang tao mien dch
chong lai tat ca cac typ huyet thanh phat hien tren the gii.
64
- Chat bo tr la Diluvac Forte
Ch nh:
Tao mien dch chu ong cho ln phong benh viem phoi va mang phoi do Actinobacillus
pleuropneumoniae gay nen.
- Ln tht:
+ Ln con khong co khang the me truyen: tiem hai lan vao 6 va 10 tuan tuoi.
+ Ln con co khang the me truyen: tiem hai lan vao 10 va 14 tuan tuoi.
- Ln hau b: tiem phong can ban giong nh ln tht. Sau o tiem nhac lai vao 4-2 tuan
trc khi e
- Ln nai: tiem vao 4-2 tuan trc khi e.
Neu ln hau b va ln nai cha tng c tiem vacxin App th phai tiem 2 lan: lan au
vao 6 tuan trc khi e, lan hai vao 2 tuan trc khi e.
- 2ml tiem bap tht sau pha sau tai.
- e tranh ln non ma, ngng cho ln an vai gi trc khi tiem phong.
- Han ngng dung: Khong can thi gian ngng dung vacxin trc khi giet th.
Trnh bay: Lo 20ml (10 lieu) va 100ml (50 lieu)
Chu y:
- S dung het lo vacxin sau khi m nap.
Sau khi tiem ln kem an, l va sot nhe, cac trieu chng nay se giam trong vong 24 gi.
32. VACXIN POLYPLEUROSIN INJ
ac tnh:
Vacxin vo hoat dang dung dch. Trong 1 lieu 2ml cha:
65
Pasteurea mutocida (serotyp A) - minimum 5,2.109.
Pasteurela mutocida (serotyp D) - minimum 2,8.109.
Actinobacillus pleuropneumoniae (serovar 2) - minimum 5,6.109.
Actinobacillus pleuropneumoniae (serovar 9) - minimum 5,6.109.
Bordetella bronchiseptia - minimum 4.109
Ch nh:
POLYPEUROSIN INJ c ch nh phong hoi chng ho th gay ra bi Pasteurella
multocida (serotyp D), Actinobacillus pleuropneumoniae (serovar 2), Actinobacillus
pleuropneumoniae (serovar 9), Bordetella bronchiseptica.
- Lac ky trc khi dung
- Tiem bap tht
- Vi nai va hau b: 4 tuan va 2 tuan trc khi e vi lieu 3ml/con
- Vi ln con: 1ml cho ln 4 tuan tuoi, 2ml cho ln 6 tuan tuoi.
Chong ch nh: Khong tiem cac loai vacxin khac trong vong 14 ngay trc va sau khi
tiem vacxin nay.
Trnh bay: Chai 5 lieu, 10 lieu.
Bao quan: nhiet o 2-80C.
Han s dung: 24 thang ke t ngay san xuat
Nha san xuat: BIOVETA - Czech Repubic
Nha phan phoi: Cong ty Thuoc thu y Xanh (GREENVET
186 Trng Chinh, ong a, Ha Noi - Tel: (84.4) 35659240, Fax: (84.4) 35659593.
33. VACXIN PORCILIS COLI
(Vacxin vo hoat phong benh tieu chay do vi khuan E.coli tren ln con s sinh)
ac tnh:
- Porcilis coli la vacxin vo hoat phong benh tieu chay tren ln con s sinh do vi khuan
E.coli gay ra. Porcilis coli cha giai oc to LT, khang nguyen long t K88ab, K88ac,
K99 va 987P.
- Chat bo tr: nc trong dau.
Ch nh:
Tiem phong cho ln me tao mien dch cho ln con s sinh qua sa au phong tieu chay
do E.coli gay nen.
66
Ln hau b va ln nai mang thai: Ln hau b va ln nai cha tng c tiem vacxin
porciis coli, trc o can tiem hai lieu vacxin cach nhau 5-6 tuan, lieu au tien khong
muon hn 8 tuan trc khi e.
Tiem nhac lai: Tiem mot lieu vao bat c luc nao gia hai la e nhng khong muon hn
2 tuan trc moi la e.
Lieu lng va cach s dung: 2ml tiem bap tht sau pha sau tai.
Trnh bay: Lo 20ml (10 lieu) va 50ml (25 lieu).
Bao quan: nhiet o 2-80C, tranh ong a va tranh anh sang.
Chu y:
- S dung het lo vacxin sau khi m nap.
34. VACXIN PORCINE PILI SHIELDTM
(Vacxin vi khuan vo hoat nga benh tieu chay va benh sng phu au tren ln con)
Nhng net chung cua benh:
- Cho ti nay, benh tieu chay do E.coli van c xem la nguyen nhan gay chet hang au
tren ln con, ty le t vong co the len en 42%.
- Benh thng xay ra tren ln 2-3 tuan tuoi cho ti giai oan ln cai sa. Dch long tran
ngap long ruot.
- Bieu hien lam sang: ln tieu chay nang. Tuy nhien, the cap tnh khong thay ln b
tieu chay v cac dch long a b gi lai trong long ruot ln.
- Ngoai ra, ln co the mac chng sng phu au do E.coli giai oan sau cai sa. The
loai benh nay gay phu co hong va cac ong th dan en t vong. Trieu chng than kinh
thng xuat hien gia thi ky benh.
Thanh phan:
Vacxin vo hoat cha cac chung K88, K99, 987P va F41.
ac tnh thuan li cua san pham:
- Neu nai t va nai ra c tiem phong trc khi e th ln con e ra bu sa me c bao
67
ho ngay t ban au do trong sa me cha khang the. Nh vay khong can s ho tr g them.
- Tren 90% benh trang tieu chay ln con do khuan E.coli gay ra hoac mot hay tat ca cac
chung K88, K99, 987P va F44. Porcine Pili Shield co cha u 4 chung tren nen u sc bao
ho ln con bat c moi trng nuoi va the benh nao.
C che tac dung va lieu lng:
- Khang the do ln me tao ra trong sa au se canh tranh v tr bam dnh cua vi khuan
lam chung khong con bam vao thanh ruot e phat trien oc to gay tieu chay ln con.
- Nai ra va nai t: 2-5 tuan trc moi la e tiem lieu 2ml/con, tiem nhac lai trc 2 tuan
cac la e ke tiep.
- Ln con t 7-10 ngay tuoi tiem lieu 0,5ml/con. Tiem nhac lai luc 3-4 tuan tuoi vi lieu
1ml/con.
- Can bo sung them lieu tr khang sinh va cung cap che o dinh dng ay u va can oi.
Bao quan: nhiet o 20 - 70C. Tranh ong a.
Chu y:
- Khong tiem phong cho ln trong vong 21 ngay trc khi giet mo
- Lac ky lo vacxin. Khi a m lo, huy toan bo lo va vacxin d tha.
- Phan ng bat li t khi xay ra. Neu co, s dung Epinephrine
- e am bao mien dch tot cho ln con khi tiem vacxin nay. Tat ca ln con phai c
bu sa au ay u luc s sinh.
Trnh bay: Lo 20ml/10 lieu va lo 100ml/50 lieu.
35. VACXIN TU HUYET TRUNG LN
ac tnh:
- La vacxin vo hoat, che t vi khuan Pasteurella multocida chung FgHC.
- Vacxin an toan, tao mien dch tot khi tiem phong cho ln.
Ch nh: Dung gay mien dch chu ong phong benh tu huyet trung cho ln khoe manh.
Thanh phan
- Moi 1ml vacxin cha t nhat 1010 te bao vi khuan Pasteurella multocida chung FgHC.
- Chat bo tr: Phen chua hoac keo phen.
Cach s dung:
- Lay vacxin ra khoi ni bao quan e cho mat 1 gi va lac ky trc khi dung.
68
- Tiem di da hoac bap tht sau goc tai hoac mat trong ui cho ln ln hn 1 thang tuoi,
vi lieu 2ml/con.
- Lch tiem phong:
+ Ln con: tiem 2 lan
Lan 1: Ln 20-30 ngay tuoi, lieu 1ml/con
Lan 2: Ln 40-50 ngay tuoi, lieu 2ml/con
+ Ln nai va c giong: Tiem lieu 2ml/con. Moi nam chung mot lan trc mua ma
khoang 1 thang.
Chu y: S dung het vacxin trong ngay.
Trnh bay:
Vacxin ong chai: 10ml cha 5 lieu
20ml cha 20 lieu
50ml cha 25 lieu
Bao quan: e vacxin nhiet o 2-80C. Khong e vacxin vao ngan ong.
36. VACXIN PHO THNG HAN LN VO HOAT
ac tnh:
- La vacxin vo hoat, chet t vi khuan Salmonella choleraesuis chung Kunzendorf.
- Vacxin an toan, tao mien dch tot khi tiem phong cho ln.
Ch nh:
Dung gay mien dch chu ong phong benh pho thng han cho ln khoe manh t 20
ngay tuoi tr len.
Thanh phan:
- Moi 1ml vacxin cha t nhat 100 te bao vi khuan Salmonella choleraesuis .
Cach s dung:
- Lay vacxin ra khoi ni bao quan, lac ky trc khi dung.
- Tiem di da hoac bap tht sau goc tai hoac mat trong ui.
- Lch tiem phong cho ln con:
+ Lan 1: ln 20-30 ngay tuoi, lieu 1ml/con.
+ Lan 2: ln 40-50 ngay tuoi (3 tuan sau khi tiem lan 1), lieu 2ml/con.
69
Chu y:
- S dung het vacxin trong ngay.
- Vacxin co the gay phan ng phu sau khi tiem trong mot so t trng hp.
Trnh bay:
ong chai: 10ml cha 5 lieu
20ml cha 10 lieu
50ml cha 25 lieu
III. VACXIN DUNG CHO GIA CAM
1. VACXIN PHONG CUM GIA CAM SUBTYP H5N1 NHU DAU
Ten vacxin: Vacxin cum gia cam vo hoat, subtyp H5N1 chung RE-1.
Thanh phan: Vacxin cha virus cum gia cam A/Harbin/Re 1/2003 (H5N1), vo hoat vi
chat bo tr nhu dau.
Muc ch: Vacxin dung phong benh cum cho ga, vt, ngong gay ra do virus cum gia
cam, subtyp H5N1.
Cach dung va lieu lng:
Cach dung: tiem bap (ngc) hoac di da (1/3 di sau co)
Lieu lng:
- Ga 14-35 ngay tuoi lieu 0,3ml/con
- Ga t 35 ngay tuoi tr len lieu 0,5ml/con.
- Ga giong, ga e: lieu 0,5ml/con va c 6 thang dung vacxin tiem nhac lai mot lan.
- Vt 14-35 ngay tuoi lieu 0,5ml/con, lieu 1ml/con va sau o c 6 thang tiem phong nhac
lai 1 lan lieu 1ml/con.
- Ngong 14-35 ngay tuoi tiem 0,5ml/con. Tiem lan 2 sau khoang 28-35 ngay so vi lan tiem
au tien, lieu 1-1,5ml/con va sau o c 4 thang tiem phong nhac lai 1 lan, lieu 1,5ml/con.
Tac dung: Dung vacxin nay thng khong gay bat ky anh hng phu nao. Tuy nhien
co the thay giam san lng trng trong thi gian ngan khi tiem phong vacxin cho ga e.
Nhng chu y khi s dung vacxin:
- Khong dung vacxin cho ga b benh cum gia cam hay ga om yeu.
- Khong lam ong lanh vacxin.
- Khong dung lo vacxin b v hoac co hien tng tach lp dau va nc.
- Lo vacxin nen e am t nhien e at en nhiet o phong trc khi dung. Sau khi m
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lo vacxin nen dung trong vong 24 gi. Thng xuyen thay kim trong khi tiem vacxin.
- Khong s dung vacxin cho gia cam se c giet mo trong vong 28 ngay.
ong goi: Lo 50ml; 100ml; 250ml
Bao quan: Bao quan 2 - 80C, trong bong toi
Han dung: 12 thang
Nha san xuat: Cong ty Phat trien Cong nghe Sinh hoc Harbin Weike, Trung Quoc
2. VACXIN NOBILIS INFLUENZA H5N2
(Vacxin vo hoat phong benh cum ga do subtyp H5N2 gay nen)
Mo ta: Vacxin vo hoat cha typ phu H5N2, thuoc typ A cua virus gay benh cum ga.
Cha dong A/chicken/Mexico/232/94/CPA.
Vacxin Nobilis Influenza H5 co hai qui cach: 1.000 lieu (lieu khuyen cao 0,5ml) hoac
2000 lieu (lieu khuyen cao 0,25ml). Ca hai qui cach nay eu cha trong 500ml.
Chat bo tr:
Vacxin Nobilis Influenza H5N2 la vacxin dang nc trong dau. Pha nc cha khang
nguyen vo hoat Avian Influenza typ A, typ phu H5N2 c tron vi nc pha dau tao nen
chat bo tr nhu dau e tang cng mien dch.
Ch nh s dung:
Vacxin Nobilis Influenza H5N2 dung e tao mien dch chu ong cho ga khoe manh
chong lai virus Avian Influenza typ A, typ phu H5.
Chng trnh tiem phong khuyen cao:
Tiem phong cho ga vao luc 8-10 ngay tuoi. Ga e va ga giong nen tiem nhac lai sau lan
au 6-10 tuan. Lan tiem th hai khong c muon hn 4 tuan trc khi ga vao e. Trong
trng hp khan cap co the tiem khi ga ang thi ky e trng.
Tiem phong khan cap:
- Tiem phong mui au tien cho tat ca ga moi la tuoi.
- Tiem nhac lai 4 en 6 tuan sau o.
- Neu tiem mui au tien cho ga di 3 tuan tuoi th nen tiem mui th 3 luc 16-18 tuan tuoi.
Tiem phong cho nhng an ga tai nhap tr lai vung co benh cum ga trc o:
Vung co nguy c nhiem benh cao:
- Tiem mui au tien luc 1 ngay tuoi (tiem 1/2 lieu)
- Tiem nhac lai luc 4-6 tuan va 16-18 tuan tuoi.
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Vung co nguy c nhiem benh thap:
- Tiem mui au tien luc 4 tuan tuoi.
- Tiem mui th hai luc 16-18 tuan tuoi.
Lieu lng: 0,5ml/ga oi vi lo 1000 lieu va lieu 0,25 ml/ga oi vi lo 2000 lieu.
Tac dung khong mong muon:
- oi vi ga khoe khong co bieu hien phan ng sau khi tiem.
- Co the sng nhe tai v tr tiem.
Thi gian ngng s dung vacxin: Khong
ac biet chu y khi s dung:
- Ch dung cho ga khoe.
- Trc khi s dung vacxin, e vacxin am len at nhiet o phong (15-250C).
- Lac ky trc khi s dung.
- S dung bm va kim tiem vo trung.
- Dung het lo vacxin a m trong vong 3 gi.
- Khong tron vi cac che pham thu y khac.
Bien phap bao ho ac biet oi vi ngi s dung vacxin:
Neu chang may tiem phai vacxin vao ngi s dung (hay ngi ke ben), phan ng cuc
bo co the xay ra, nen nh s t van cua bac sy, thong bao cho bac sy biet la vacxin vo hoat
dang nhu dau.
Bao quan: nhiet o t 2 - 80C, tranh lam ong a.
Han s dung: t nhat 24 thang ke t ngay san xuat.
Quy cach: Lo Polyethylene cha 1000 hoac 2000 lieu vacxin.
ieu kien cung cap thuoc thu y cho chu ho chan nuoi: Theo quy nh cua quoc gia
T: (84.4) 8691003
3. VACXIN NEWCASTLE CHUNG F (HE II)
(Nhc oc ong kho)
ac tnh:
- La vacxin nhc oc, ong kho, san xuat t virus Newcastle chung F nuoi cay xoang
nieu phoi trng ga.
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- Vacxin an toan, khong gay phan ng phu ngay ca khi dung cho ga con mi n.
- Mien dch keo dai c 1 thang.
Ch nh:
Dung gay mien dch chu ong phong benh Newcastle chung F.
Thanh phan:
- Moi lieu vacxin cha t nhat 106EID50 virus Newcastle chung F.
- Chat bo tr: sa khong kem.
Cach s dung:
- Nho mat hoac nho mui.
- Phng phap dung vacxin:
+ Vacxin c pha bang nc sinh ly vo trung a lam lanh vi lng sao cho mot con
ga con 2 giot cha 1 lieu vacxin.
+ Lac tan eu, dung ong hut nho cho moi ga 2 giot vao mat hoac mui.
Chu y: Sau khi pha, chai vacxin phai c gi trong nc a, tranh anh sang mat tri
va dung het trong vong 2-3 gi. Chai vacxin nay dung xong phai ngam vao chat sat trung
hay luoc soi trc khi bo i.
Dang trnh bay: ong chai 100 lieu
Bao quan: e vacxin nhiet o t 2-80C. Khong e vacxin vao ngan ong.
4. VACXIN NEWCASTLE CHUNG LASOTA
(Nhc oc ong kho)
ac tnh:
- La vacxin nhc oc, ong kho, san xuat t virus Newcastle chung Lasota, nuoi cay
xoang nieu phoi trng ga.
- Vacxin chung Lasota tao mien dch manh va dai hn chung F.
Ch nh:
Dung gay mien dch chu ong phong benh Newcastle cho ga khoe manh t 2 tuan tuoi
tr len sau khi s dung vacxin Newcastle chung F t nhat 14 ngay.
Thanh phan:
- Moi lieu vacxin cha t nhat 106EID50 virus Newcastle chung Lasota.
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Cach s dung:
- ng dung vacxin: Nho mat hoac cho uong.
- Phng phap dung vacxin:
+ Nho mat: Pha vacxin bang nc muoi sinh ly vo trung a lam lanh vi lng sao cho
va u 1 con ga 2 giot cha 1 lieu vacxin. Lac tan eu, dung ong hut, nho moi ben mat 1 giot.
+ Cho uong: e ga nhn khat t 1-2 gi trc khi cho uong. Tuy thuoc vao tuoi ga, pha
vacxin bang nc muoi sinh ly, nc cat hoac nc sach lam lanh khong cha chat tay
hoac chat sat trung. Cho ga uong theo ch dan sau:
Ga 20-25 ngay tuoi cho uong 5ml/1 lieu/con.
Ga 45 ngay tuoi cho uong 7-10ml/1 lieu/1 con.
Ga 45 ngay tuoi uong 12-15ml/1 lieu/1 con.
Chu y:
- Sau khi pha, tranh anh sang mat tri va dung het trong vong 2-3 gi. Vacxin co the gay
phan ng khi dung cho an ga co benh ho hap man tnh (CRD).
- Chai vacxin nay dung xong phai c ngam vao chat sat trung hay luoc soi trc
khi bo i.
Dang trnh bay: ong chai 100 lieu
5. VACXIN NEWCASTLE CHU NHIET
(Nhc oc ong kho)
ac tnh:
- La vacxin nhc oc, ong kho, san xuat t virus Newcastle chu nhiet chung AVF/
HR-NDV (12) nuoi cay xoang nieu phoi trng ga.
- Vacxin rat an toan ngay ca vi ga con mi n, tao mien dch manh va ong eu. Virus
vacxin co kha nang truyen ngang manh.
- Chung virus co tnh chu nhiet cao rat thuan li cho nhng ni thieu cac phng tien
lanh e bao quan vacxin.
Ch nh:
Dung gay mien dch chu ong phong benh Newcastle cho ga khoe manh moi la tuoi.
Thanh phan:
- Moi lieu vacxin cha t nhat 106EID50 virus Newcastle chung AVF/HR-NDV (12).
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Cach s dung:
Vacxin co the dung mien dch cho ga bang 3 phng phap sau:
- Nho mat, mui: Pha vacxin bang nc sinh ly vo trung a lam lanh vi lng sao cho u 1
ga con 2 giot cha 1 lieu vacxin. Lac tan eu, dung ong hut nho moi ben mat hoac mui 1 giot.
- Cho uong: e ga nhn khat t 1-2 gi trc khi cho uong. Tuy thuoc vao tuoi cua ga,
pha vacxin nh ch dan sau:
Ga 25-45 ngay tuoi cho uong 5ml/con.
Ga 45 ngay tuoi cho uong 7-10ml/con.
Ga tren 45 ngay tuoi uong 12-15ml/con.
- Cho an: Pha vacxin vi 10ml nc sach, tron eu thc an hon hp (10g/ga) hoac vi
1/2 bat cm nguoi. Dan eu tren met hoac giay sach e cho toan bo an ga an cung mot
luc vao buoi sang sm khi ang oi.
Chu y: Chai vacxin nay dung xong phai c ngam vao chat sat trung hay luoc soi trc
khi bo i.
Dang trnh bay: ong chai 25, 20 va 100 lieu.
Bao quan: e vacxin nhiet o t 2-80C hoac ni kho mat, tranh anh sang mat tri
c 1 tuan. Khong e vacxin vao ngan ong.
6. VACXIN NEWCASTLE CHUNG M (HE I)
(Nhc oc ong kho)
ac tnh:
- La vacxin nhc oc, ong kho, san xuat t virus Newcastle chu nhiet chung Muk-
teswar, nuoi cay xoang nieu phoi trng ga.
- Vacxin tao mien dch manh va ben.
- Chung virus nay co the gay benh cho ga di hai thang tuoi cha c tiem phong vi
vacxin Neucastle chung F hoac Lasota.
Ch nh:
Dung gay mien dch chu ong phong benh Newcastle lan au cho ga khoe manh t 2
thang tuoi tr len hoac tiem nhac lai cho ga di 2 thang tuoi a c tiem bang cac vacxin
Newcastle chung F, Lasota hoac vacxin Newcastle chu nhiet.
Thanh phan:
- Moi lieu vacxin cha t nhat 106EID50 virus Newcastle chung Mukteswar.
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Cach s dung:
- Tiem di da co, mat trong ui hoac bap tht c.
- Phng phap: Vacxin c pha bang nc sinh ly lanh vo trung sao cho moi lieu la
0,5ml, lac tan eu trc khi tiem.
Chu y:
- Sau khi pha, chai vacxin phai c gi trong nc a, tranh anh sang mat tri va dung
het trong vong 2-3 gi.
- Vacxin co the gay phan ng manh khi dung cho an ga mang benh ho hap man tnh (CRD).
- oi vi an ga ang e, tiem vacxin nay co the dan en giam sut san lng trng.
- Chai vacxin nay dung xong phai c ngam vao chat sat trung hay luoc soi trc khi bo i.
Dang trnh bay: ong chai 100 lieu.
7. VACXIN NOBILIS-ND CLONE 30
(Vacxin virus song nhc oc ong kho phong nga benh Newcastle)
Mo ta: Nobilis ND Clone 30 la vacxin song nhc oc ong kho phong benh
Newcastle ga. Thanh phan hoat chat la virus Newcastle song nhc oc chung
Clone 30: 6,0 log10 ELD50.
Ch nh: Dung cho ga va ga tay phong benh Newcastle.
Vacxin dung an toan cho ga 1 ngay tuoi tr len. Thi gian toi u phng phap s dung
va chung nga nhac lai phu thuoc chu yeu vao tnh hnh a phng. Do vay can hoi y kien
bac sy thu y e s dung vacxin cho phu hp.
Lieu lng: 1 lieu/ga
Cach s dung:
1. Phun sng
Vacxin c pha trong nc mat, sach khong co cha Chlorine hay chat sat. Lo vacxin
phai c m trong nc pha. Dung cu phun sng phai khong co chat ton can, chat an
mon hay chat sat trung tay ue (tot nhat ch dung dung cu nay cho viec phun sng e chung
nga cho ga). Vacxin a pha phai c phun sng tren mot so ga qui nh, cach au ga t
30-40cm, phu hp khi chung tap trung tai cho co anh sang m.
oi vi ga 1 ngay tuoi: 0,25 lt nc pha/1000 ga va ieu chnh giot sng mn (may
phun sng ch c s dung khi biet chac chan an toan cho ga).
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2. Nho mat, nho mui
Pha vacxin trong nc sinh ly man va cha trong lo nho giot chuan (30ml/1000 lieu).
Phai nho giot vacxin cach mat, mui ga vai centimet. Ngi thc hien phai xem giot vacxin
co c nho vao mui va ga co ht c khong.
Chu y: Hang INTERVET san xuat nc pha ac thu Diluent Oculo Nasal danh rieng e
pha vacxin nho mat, nho mui.
3. Pha trong nc uong
Lo vacxin phai c m trong nc pha. Phai s dung nc mat, sach, khong Chlorine
va chat sat, nen pha them 2 gam sa bot tach b cho 1 lt nc pha e virus duy tr hoat lc
lau hn. Bao am lng vacxin a pha phai c ga uong trong vong 2 gi. Tuy theo ieu
kien kh hau, can cho ga ngng uong nc trc khi uong vacxin. Phai co u so lng mang
uong cho ga. Khong co chat can, khoang hay chat sat trung ton trong mang uong.
Pha 1000 lieu vacxin trong mot khoi lng nc uong tuy theo tuoi ga nhng khong qua 40
lt. Tot nhat cho uong vacxin vao buoi sang v ay la luc mat nhat trong ieu kien kh hau nong.
Khi an ga ong hn, nen pha vacxin vao tng phan va cho he thong phan phoi nc
uong en cac khu nuoi.
Khi tnh so lieu tren so ga nuoi, nen tnh mc gii han cao th tot hn.
Lu y: Phun sng hat tho hay nho mat nho mui cho ap ng mien dch tot nhat. Nen chon
nhng phng phap nay, ac biet oi vi ga con. Thi iem toi u va phng phap phong
benh toi u tuy thuoc phan ln vao tnh hnh a phng. Can tham khao y kien bac s thu y.
Vacxin s dung an toan cho ga mot ngay tuoi tr i.
Thi gian ngng dung vacxin: Khong
Quy cach: Lo vacxin cha 1.000, 2.500 hoac 5.000 lieu. Moi hop cha 10 lo.
Bao quan: 2-80C, trong bong toi
Lu y:
- Ra sach, sat trung tay va dung cu sau khi tiem phong.
- Ch tiem phong cho ga khoe
- Vacxin phai c s dung ngay sau khi pha.
- Tranh tiep xuc vi vacxin mc toi a.
Chong ch nh: Khong co, neu tuan thu theo hng dan
Thong tin khac:
- Vacxin a pha phai s dung het trong vong 2 gi.
- Vacxin co the gay viem ket mac mat thoang qua cho ngi thao tac.
- Virus trong vacxin de dang lan truyen sang ga tiep xuc.
- Huy vo lo vacxin va vacxin a pha con tha theo quy nh cua quoc gia.
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8. VACXIN NOBILIS IB + ND + EDS
(Vacxin cha sieu vi vo hoat bao ho ga phong nga benh viem phe quan truyen nhiem
typ Massachusetts (IB), benh Newcastle (ND) va hoi chng giam e (EDS76))
Mo ta:
- Vacxin cha dong sieu vi IB co tnh tao mien dch cao sieu vi Newcastle va sieu vi Hoi
chng giam e 76 dong BC 14.
- Sieu IB typ huyet thanh Massachusetts.
- Sieu vi c vo hoat bang formalin va c phoi che vi chat phu gia nhu dau.
Ch nh:
- Vacxin c s dung e phong nga hoi chng giam e 76 va e tiem nhac lai cho
ga e thng pham va ga giong oi vi benh IB typ huyet thanh Massachusetts va benh
Newcastle.
- Vung nao co dong sieu vi IB thay oi c ghi nhan th vacxin IB co cha dong o
phai c s dung.
Lch chung nga:
- Vacxin c chung cho ga t 16-20 tuan tuoi nhng khong muon qua 3 tuan trc khi
e trng.
- e at hieu qua cao khi tiem nhac lai, an ga phai c tiem lan au vi vacxin song
IB va Newcastle.
- Ket qua at tot nhat neu viec tiem phong vacxin vo hoat IB c thc hien t 6 tuan
hay hn sau khi a tiem vacxin song trc o, nhng trong moi trng hp cung khong
c t hn hai tuan sau lan tiem vacxin song.
Khi tiem phong ung cach cung nh a tiem vacxin song trc o, an ga se phat trien
khang the u e bao ho oi vi hoi chng giam e, benh Newcastle va nhng thiet hai
trong san xuat do benh IB typ huyet thanh Massachusetts gay ra.
Phan ng khi chung nga:
- ga khoe khong co phan ng g c ghi nhan sau khi chung nga.
- Vai tuan sau khi tiem phong thay hi phong nhe cho tiem ieu nay cung khong gay ton
thng mo cho tiem neu c tiem ung cach va sat trung can than.
Lu y:
- Ch tiem cho ga khoe.
- Trc khi tiem phong phai e vacxin at c ngang nhiet o phong (15-250C).
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- Dung cu tiem phai sat trung can than.
- Lo vacxin a m phai c s dung trong vong 3 gi.
- Khong tron lan vi cac loai vacxin khac.
- Neu ngi thc hien thao tac do vo y hay b ngi ben canh am kim phai th phan ng tai
cho tiem co the xay ra. Phai lien he bac s e xem xet va bao cho biet ay la vacxin nhu dau.
Bao quan va qui cach: 2-80C, tranh ong a, lo vacxin cha 1000 lieu.
9. VACXIN NOBILIS NEWCAVAC
(Vacxin cha sieu vi vo hoat bao ho ga phong nga benh Newcastle)
Mo ta:
Vacxin nga benh Newcastle cha sieu vi Newcastle dong Clone 30 co tnh mien dch
cao va c vo hoat bang formalin, dang nhu dau.
Ch nh:
Tao mien dch phong nga benh Newcastle ga, ga tay va cac loai gia cam khac man
cam vi benh nay.
Lch tiem phong:
Mac du Nobilis Newcavac co the s dung lan au cho ga moi la tuoi nhng hieu qua
tot nhat khi s dung cho ga a c tiem trc o vi vacxin song (Nobilis ND Clone 30,
Lasota hoac Hitchner B1). Cung co the tiem Nobilis Newcavac cho ga ang khai thac
trng ma khong gay thiet hai nh cac loai vacxin khac.
Ga giong va ga e: Tiem lan au vi Nobilis ND Clone 30, Hitechner B1 hoac Lasota,
cho vao nc uong hay phun sng t nhat 2 lan trc 12 tuan tuoi, tiem Nobilis Newcavac
vao 16-20 tuan tuoi.
Ga tay: Tiem lan au vi Nobilis ND Clone 30, Hitchner B1 hoac Lasota, pha nc
uong hay phun sng, tiem Nobilis Newcavac luc 15-17 tuan tuoi va tiem nhac lai luc
26-30 tuan tuoi.
Can tham khao y kien cua bac sy thu y tai a phng ve lch tiem phong
Tiem 0,5ml/ga, tiem bap hoac tiem di da co.
Phan ng khi tiem vacxin:
- ga khoe khong co trieu chng g ang ke. Vai tuan sau khi tiem thay hi phong nhe
tai cho tiem. ieu nay khong ton hai g en te bao mo neu dung cu tiem c sat trung ky.
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- Neu ga giet mo trong vong 1 thang th viec tiem phong c khuyen cao ap dung di da.
Mien dch:
ga c tiem phong trc o vi vacxin song, khang the a hnh thanh sau o 1 tuan
va at nh cao 3 tuan sau o. Noi chung an ga c tiem nhac lai vi Nobilis Newcavac
se at mc bao ho lau ben trong suot chu ky e vi bien o tuy ca the. V the ga con cua
cac an tren at mc khang the me truyen sang va cao va ong eu phong chong benh
Newcastle. ieu nay tao ieu kien de dang cho ke hoach tiem phong chung sau nay.
Lu y:
- Ch tiem cho ga khoe
- Trc khi tiem phong phai e vacxin nhiet o phong (15-250C).
- Neu ngi thc hien thao tac do vo y hay b ngi ben canh am kim phai th phan
ng tai cho tiem co the xay ra. Phai lien he bac s e xem xet va bao cao cho biet ay la
vacxin nhu dau.
Bao quan: 2-80C, tranh ong a.
Trnh bay: Lo vacxin 500ml cha 1000 lieu.
10. VACXIN NDLS VAC
(Vacxin song, ong kho, phong benh Newcastle ga. c nhap khau t Cong ty
ChoongAng Han Quoc)
Thanh phan: NDLS VAC c dung e tao mien dch cho ga chong benh Newcaste
(ND). Vacxin cha virus Newcaste nhc oc chung Lasota c nuoi cay trong phoi trng
ga sach benh.
Cach dung:
Dung 1 lan: ga con t 8-10 ngay tuoi
Dung 2 lan ga 18-20 ngay tuoi
Lieu dung:
1. Neu dung vacxin qua ng uong
- Ngng cho ga uong nc t nhat 2 gi trc khi dung vacxin.
- Pha 1000 lieu vacxin vi nc sach, lanh t nhien theo ty le trong bang sau:
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2. Neu dung vacxin qua ng nho mat: dung 30ml nc pha vi 1 lo vacxin/lieu 1000
con. Nho 1 giot (0,03ml) dung dch vacxin vao mat tng con ga, i cho en khi giot vacxin
tan eu trong mat mi tha ga ra.
Chu y:
- Ch dung vacxin cho nhng an ga khoe manh
- Ngng s dung cac chat sat trung trong nc uong trong vong 48 gi trc va 24 gi
sau khi dung vacxin.
- Dung nc sach, lanh t nhien e pha vacxin (nc pha vacxin khong cha cac chat
sat trung).
- Vacxin nay bao gom virus song do o moi ieu kien ve bao quan hoac s dung khong
tot co the lam mat hoat lc cua vacxin. Bao quan vacxin nhiet o 2-80C, tranh anh sang.
- Ch pha u lng vacxin khi can thiet va s dung ngay sau khi pha.
- Sau khi tiem xong phai huy tat ca cac vo lo cha vacxin va vacxin con tha.
Ghi chep: Ghi lai so lo, ngay het han dung, ngay tiem phong, ni an ga c tiem va
tat ca cac phan ng thay c.
Dang trnh bay:
- 500 lieu/1lo, 10 lo/1 hop
- 1000 lieu/1lo, 10lo/1 hop
Nha phan phoi: Cong ty CP Phat trien Cong nghe Nong thon (RTD).
11. VACXIN NBBH VAC
(Vacxin song, ong kho, phong benh Newcastle va viem phe quan truyen nhiem. c
nhap khau t Cong ty ChoongAng Han Quoc)
Thanh phan: NBBH VAC c dung e tao mien dch cho ga chong benh Newcaste
va viem phe quan truyen nhiem. Vacxin cha virus Newcaste va virus gay benh viem phe
quan truyen nhiem nhc oc, c nuoi cay trong phoi trng ga sach benh.
Cach dung:
Dung lan 1: ga con t 8-10 ngay tuoi
Dung lan 2: ga 18-20 ngay tuoi
Mien dch c tao ra sau 7 ngay va keo dai 3 thang
Lieu dung:
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2. Neu dung vacxin qua ng phun kh dung: 1000 lieu vacxin trong ong thuoc pha vao
o 500ml nc t nhien. Phun vacxin len ga, dung may phun kh dung tao hat sng nho.
Chu y:
- Dung nc sach, lanh t nhien e pha vacxin (nc pha vacxin khong cha cac chat sat trung).
- Ch pha u lng vacxin can dung va s dung ngay sau khi pha.
- Sau khi tiem phong xong phai huy tat ca cac vo lo cha vacxin va vacxin con tha.
Ghi chep: Ghi lai so lo, ngay het han dung, ngay tiem phong, ni an ga c tiem va
tat ca cac phan ng quan sat c.
Dang trnh bay:
Khu CN An Khanh - Hoai c - Ha Noi - Tel: (84.4) 0343650574
12. VACXIN IBD VAC
(Vacxin song, ong kho, phong benh Gumboro ga. c nhap khau t Cong ty
ChoongAng Han Quoc)
Thanh phan: IBD VAC c dung e tao mien dch cho ga chong benh Gumboro
(benh viem tui fabricius). Trong vacxin cha virus Gumboro nhc oc, c nuoi trong
phoi trng ga sach benh.
Cach dung:
Dung lan 1: ga con t 5-7 ngay tuoi
Dung lan 2: ga 12-14 ngay tuoi
Mien dch c tao ra sau 7 ngay va keo dai 2-3 thang
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Lieu dung:
2. Neu dung vacxin qua ng phun kh dung: 1000 lieu vacxin trong ong thuoc pha vao
o 500ml nc t nhien. Phun vacxin len ga, dung may phun kh dung tao hat sng nho.
Chu y:
- Dung nc sach, lanh t nhien e pha vacxin (nc pha vacxin khong cha cac chat
sat trung).
- Ch pha u lng vacxin can dung va s dung ngay sau khi pha.
- Sau khi dung xong phai huy tat ca cac vo lo cha vacxin va vacxin con tha.
Ghi chep: Ghi lai so lo, ngay het han dung, ngay chung nga, ni an ga c tiem
phong va tat ca cac phan ng quan sat c.
Dang trnh bay:
13. VACXIN GUMBORO ONG KHO
ac tnh:
- La vacxin nhc oc, ong kho, san xuat t chung virus Gumboro, nuoi cay tren te
bao x phoi ga.
- Vacxin an toan, tao mien dch tot va khong gay c che ap ng mien dch oi vi cac
loai vacxin khac.
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Ch nh:
Dung gay mien dch chu ong phong benh Gumboro cho ga khoe manh
Thanh phan:
- Moi lieu vacxin cha t nhat 103TCID50 virus Gmboro nhc oc.
Cach s dung:
- Phng phap dung vacxin: nho mat, uong hoac tiem di da.
- Cho uong hoac nho mat tng con:
+ Pha vacxin vi nc sinh ly vo trung a lam lanh sao cho 2 giot cha 1 lieu vacxin.
+ Lac tan eu, dung ong hut nho vao xoang mieng hoac mat ga 2 giot, moi ben mat 1 giot.
- Cho uong ca an:
e ga nhn khat t 1-2 gi trc khi cho uong. Tuy thuoc vao tuoi cua ga, pha vacxin
bang nc sinh ly hay nc sach lam lanh khong cha chat tay hoac sat trung va cho ga
uong vi so lng nh sau:
+ Ga 25-45 ngay tuoi, cho uong 5ml/1lieu/con.
+ Ga >45 ngay tuoi, cho uong 7-10ml/1lieu/con.
- Lch tiem chung: e tao c mien dch ay u, ga phai c dung vacxin 2-3 lan.
+ Lan 1: t 5-10 ngay tuoi.
+ Lan 2: t 20-25 ngay tuoi.
Chu y:
- Sau khi pha chai vacxin phai c gi trong nc a, tranh anh nang mat tri va dung
trong vong 2-3 gi, dung xong phai c ngam vao chat sat trung hay luoc soi trc khi bo i.
- Khong nen s dung vacxin Gumboro ong thi vi cac loai vacxin khac.
Dang trnh bay: - e vac xin nhiet o 20C - 80C. Khong e vac xin vao ngan ong.
14. VACXIN NOBILIS GUMBORO D78
(Vacxin cha sieu vi song ong kho bao ho cho ga phong nga benh Gumboro)
Mo ta:
Nobilis Gumboro D78 la vacxin song ong kho phong benh Gumboro. Moi lieu cha t
nhat 4.01og10 TCID50 virus Gumboro dong D78.
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Ch nh: Tao mien dch chu ong phong nga benh Gumboro.
Chng trnh chung nga:
Nobilis Gumboro D78 co the dung cho ga t 7-28 ngay tuoi. Dong D78 hieu qua oi vi
mc o khang the me truyen trong an t 7-28 ngay tuoi. Thi iem toi u e tiem phong
tuy thuoc vao mc o cao cua khang the me truyen. Trong trng hp khang the me truyen
khong ong eu trong an ga, nen tiem phong hai lan cach nhau 1 tuan.
Nobilis Gumboro D78 cung co the dung cho ga con 1 ngay tuoi khi khang the me truyen
thap hay khong co.
Mien dch: Dau hieu ap ng mien dch au tien quan sat c trong vong 1 tuan sau
khi dung.
Lieu dung: 1 lieu/con
Cach s dung:
- Phng phap cho uong: pha vacxin vao nc uong sao cho ga uong het trong vong 2 gi.
- Phng phap phun: vacxin pha vao trong nc vi mc 1.000 lieu trong 1 lt nc. Phai
phun hat tho len tren ga t khoang cach 30-40cm.
- Nho mat, nho mui: vacxin pha vao dung dch nc muoi sinh ly (thng 30ml/1.000
lieu) va dung bang ong nho chuan. Nho 1 giot vao mot mat hoac mot ben mui ga t khoang
cach vai centimet.
INTERVET co san xuat san nc pha Oculo/nasal diluent e s dung vi muc ch nho
mat/mui.
Phan ng phu:
Khong co phan ng g xay ra sau khi dung cho ga khoe manh.
Thi gian ngng dung vacxin: Khong
Lu y:
- Ra va sat trung tay va dung cu sau khi chung nga, vacxin con tha phai huy bo bang
cach ot hay nau soi.
- Ch dung cho ga khoe manh.
- Dung vacxin ngay sau khi m lo.
Bao quan: Bao quan lanh t 2-80C, tranh anh sang.
15. VACXIN NOBILIS GUMBORO 228E
(Vacxin cha sieu vi song ong kho bao ho cho ga phong nga benh Gumboro)
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Mo ta:
Nobilis Gumboro 228E la vacxin song ong kho phong benh Gumboro, phat trien tren
te bao phoi trng. Moi lieu cha t nhat 2.01og10 TCID50 virus Gumboro dong 228E.
Ch nh: Tao mien dch chu ong phong nga benh Gumboro.
Cach ap dung: Vacxin co the pha vao nc cho uong, pha vi mot lng nc can thiet
e ga uong het trong vong 2 gi.
Lch tiem phong: Virus vacxin dong 228E la dong trung gian the va, do o virus co kha
nang vt qua s hien dien cua khang the me truyen sang giai oan sm hn va phat tan
tot hn trong an ga c s dung vacxin.
Ga con co the ap ng mien dch tot tuy thuoc vao ham lng khang the me (MDA)
hien dien va v the viec tiem phong phai can c vao loai ga va cach tiem phong trc ay
cho ga bo me.
Hng dan:
- Ga con tht t ga bo me a c chung vacxin song trc o: dung vacxin t 7 en 14
ngay tuoi.
- Ga con tht t ga bo me a c chung vacxin vo hoat trc o: dung vacxin t 14
en 17 ngay tuoi.
- Ga hau b t ga bo me a c chung vacxin song trc o: dung vacxin t 14 en 21
ngay tuoi.
- Ga hau b t ga bo me a c chung vacxin vo hoat trc o: dung vacxin t 21 en
28 ngay tuoi.
Mien dch: at mien dch bao ho cho ga sau khoang 1 tuan dung thuoc.
Phan ng khi dung thuoc: Phan ng khong ang ke khi dung cho ga khoe manh.
Nhng ieu lu y:
- Ch dung vacxin cho ga khoe manh v ga yeu hay ga benh khong the phat trien mien
dch u sc e bao ho.
- Vacxin phai c s dung het trong vong 2 gi sau khi pha.
- Khong s dung lo vacxin a hong.
Bao quan: Bao quan lanh t 2-80C, tranh anh sang.
16. VACXIN NOBILIS RISMAVAC + CA126
(Vacxin cha sieu vi song phong nga benh Mareks ga)
Mo ta:
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Vacxin song dung tao mien dch chu ong cho ga phong benh Marek. Moi lieu vacxin
co cha:
- Virus Marek CHV song chung CVI0988: 3.0 log10 pfu
- Virus Marek THV chung FC-126: 3.0 log10 pfu
Cong thc: The van te bao ong lanh bao quan trong nit long.
Ch nh: Dung cho ga con 1 ngay tuoi tao mien dch chu ong chong lai benh Marek.
S dung vacxin nay khi co cac chung virus Marek oc lc rat cao lu hanh.
Chng trnh tiem phong: tiem phong cho ga con 1 ngay tuoi
Lieu lng: 0,2ml/ga
Cach s dung: tiem di da co hoac c ui.
Thi gian ngng dung: khong
Quy cach: 1 bo gom 1 ampul vacxin cha Herpes virus ga chung CVI-988 va Herpes
virus ga tay chung FC-126 va ampul vacxin c cai vao bm tiem kim loai va a vao
bnh nit long e bao quan.
Bao quan:
- Bao quan trong nit long (-1960C).
- Ampul vacxin bao quan trong nit long.
- Nc pha bao quan nhiet o phong.
- Bao quan thung cha vacxin can than, nap quay len tren, at ni kho, thong thoang
va tranh xa khu vc a trng vao may ap.
Lu y:
- Thung nit long va vacxin giao cho ngi c huan luyen thao tac vi nit long va
nhiet o cc thap quan ly s dung.
- Can than trong tranh lam vay vacxin len tay, mat, quan ao.
- Toan bo lo vacxin a pha phai s dung ung theo hng dan.
Chong ch nh: Khong co.
Cac thong tin khac:
- Khong tron lan vi vacxin khac.
- Huy vo lo va vacxin tha theo quy nh cua quoc gia.
- Bao quan ampul vacxin trong nit long cho en khi chuan b tiem.
- Ch s dung ampul vacxin c lam ra ong ngay trc khi tiem.
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17. VACXIN MD-VAC CFL (MAREK)
(Serotyp 3. Virus song)
MD-VAC CFL la vacxin song ch dung cho ga con 1 ngay tuoi khoe manh, e phong
nhng trieu chng va ton thng do benh Marek.
Hng dan s dung Vacxin MD-VAC CFL
1. Ch s dung cho ga khoe 1 ngay tuoi.
2. Tranh cho ga tiep xuc vi virus Marek.
3. Ch dung dung dch pha loang cua Fort Dodge Animal Health. Lng dung dch pha
loang chnh xac c cung cap trong moi vacxin. Bao quan dung dch pha loang nhiet o
khong qua 270C.
4. Loai 1.000 lieu: ch pha loang 1 lo (1.000 lieu) vi 200ml dung dch pha loang Fort
Dodge Animal Health.
Loai 2.000 lieu: ch pha loang 1 lo (2.000 lieu) vi 400ml dung dch pha loang Fort
Dodge Animal Health.
5. Bo nap gia cua nap nhom e lai phan nhom bao quanh lo. Lau sach nut cao su cua
lo vacxin va lo dung dch pha loang vacxin bang con.
6. Dung bm tiem va kim tiem vo trung, hut 3ml dung dch pha loang cho vao lo vacxin.
7. Rut bm tiem va kim tiem ra. Tron ky va nhe nhang cho ti khi vacxin c hoa tan
het. Hut vao bm tiem 2-3ml khong kh. ieu nay rat quan trong.
8. am lai kim tiem vao lo vacxin, cho khong kh vao lo (e pha v chan khong).
9. at ngc lo vacxin, hut het vacxin a c pha loang vao bm tiem.
10. Cho toan bo vacxin vao lo dung dch pha loang. Tron nhe nhang va ky. Vacxin pha
loang a co the dung.
11. Trong qua trnh tiem vacxin duy tr lo vacxin a c pha loang 21-270C. Neu
nhiet o cao hn at lo vacxin a pha loang vao chau a.
12. Khi tiem vacxin dung kim so 22-20G, kim dai khoang 1-1,4cm. Tat ca cac thiet b,
dung cu phai vo trung va kim c thay oi thng xuyen.
13. Tiem cho moi ga 0,2ml vao di da.
14. S dung toan bo vacxin a pha loang trong vong 1 gi. Khong s dung lai nhng
vacxin a pha loang. ot het cac lo cha vacxin va vacxin con tha.
Chu y:
- Vacxin phai c bao quan, van chuyen va s dung theo ung hng dan.
- Ghi chep so lo vacxin, han s dung, ngay nhan va ngay tiem vacxin ni tiem vacxin
va bat ky phan ng g quan sat c.
- Ch tiem di da
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- Khong tiem vacxin trong vong 21 ngay trc khi giet mo.
- Lo vacxin a m ra phai s dung het. ot het cac lo ng vacxin va vacxin con tha.
Bao quan: Gi vacxin nhiet o t 2-70C.
Dang trnh bay:
- 1.000 lieu/lo, 10 lo/1 hop
- 2.000 lieu/lo, 10 lo/1 hop
18. VACXIN AU GA ONG KHO
ac tnh:
- La vacxin nhc oc, ong kho, san xuat t virus au ga chung Weybridge nuoi cay
tren te bao x phoi ga.
- Vacxin an toan, tao mien dch tot va keo dai.
Ch nh:
Dung gay mien dch chu ong phong benh au ga cho ga con 1 tuan tuoi khoe manh.
Thanh phan:
- Moi lieu vacxin cha t nhat 104TCID50 virus au ga nhc oc chung Weybridge.
Cach s dung:
- Pha vacxin vi 1-2ml nc sinh ly.
- Lac eu vacxin, dung kim chung (co the dung ngoi but hoac kim khau) nhung ngap
vao vacxin, sau o chch vao vung da mong mat trong canh ga.
Kiem tra v tr chung vacxin sau 5-7 ngay, neu thay noi len nhng not trang, nho la at.
Neu cha thay moc not au th phai chung lai vao v tr oi dien.
Chu y:
- Sau khi pha, chai vacxin phai c gi trong nc a, tranh anh nang mat tri va dung
trong vong 2-3 gi.
- Chai vacxin dung xong phai c ngam vao chat sat trung hay luoc soi trc khi bo i.
Dang trnh bay: ong chai 100 lieu.
Bao quan: nhiet o 2-80C. Khong e vacxin vao ngan ong.
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19. VACXIN NOBILIS CAV P4
(Vacxin virus song nhc oc ong kho phong nga benh thieu mau)
Mo ta:
Nobilis CAV P4 la vacxin song nhc oc ong kho phong benh thieu mau ga.Thanh
phan hoat chat trong moi lieu vacxin: virus benh thieu mau (CAV) song nhc oc dong
26P4: 3.0log10TCID50.
Ch nh: Dung phong benh thieu mau cho ga t 6 tuan tuoi tr i trc khi ga bat au e.
Vacxin s dung cho ga t 6 tuan tuoi tr i. e am bao ham lng khang the u cao
trc khi ga bat au e can tiem phong cho an ga giong t nhat 6 tuan trc khi chu ky e
bat au. Co the tiem phong vacxin benh thieu mau ga ket hp vi vacxin virus REO song
hoac vo hoat (tiem bap hoac di da) hoac ket hp vi chung au (xuyen mang canh).
Lieu lng: 0,2ml/ga
Cach s dung:
Tiem bap hoac di da:
- Pha lo vacxin ong kho vao nc pha Dilavia cua INTERVET, dung 200ml nc pha
cho 1.000 lieu vacxin.
- Tiem bap hoac di da 0,2ml vacxin a pha cho moi con ga.
Chung canh:
- Pha lo vacxin vao nc pha Unisolve cua INTERVET, 13ml cho 1.000 ga.
- Nhung ngap kim chung oi vao dung dch vacxin sao cho ca 2 kim cung cha ay vacxin
trc khi chung tng con ga. Xuyen kim cha vacxin vao mang canh t pha di len tren.
e s dung vi vacxin vo hoat, pha lo vacxin ong kho vao 2ml muoi em phosphate
vo trung roi tron vao lo vacxin vo hoat, lac ky trc khi s dung.
Thi gian ngng s dung: Khong
Quy cach: Lo vacxin cha 1.000 lieu
Bao quan: 2-80C, trong bong toi.
Chong ch nh: Khong dung vacxin khi ga ang trong chu ky e.
Lu y:
- Ch tiem phong cho ga khoe.
- Vacxin ch c s dung trong vong 4 gi sau khi pha.
- Co the s dung vacxin Nobilis CAV P4 ket hp vi Nobilis Reo 1133, Nobilis OVO
Diphterin va vacxin virus vo hoat cua INTERVET.
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- Ra sach va sat trung tay va dung cu sau khi tiem phong.
- Vacxin tha phai huy bang cach ot hoac un soi. Huy vo lo vacxin va vacxin tha
theo quy nh cua quoc gia.
20. VACXIN NOBILIS REO 1133
(Vacxin sieu vi song ong kho phong nga benh viem khp truyen nhiem (REO) tren
gia cam)
Mo ta:
Vacxin nhc oc cha Reovirus dong 1133, moi lieu cha t nhat 3.1.log10 TCID50 virus
phat trien trong phoi ga vo trung.
Ch nh:
Tao mien dch giup cho ga c bao ho vi benh viem khp luc ga 5 ngay tuoi hay ln hn.
Vacxin cung c dung e chung lan au cho ga hau b giong.
Lch tiem phong:
Vacxin phai c dung ung cach cho ga khoe nham co c ap ng vacxin tot trong
moi trng nuoi tot. Them vao o, s ap ng vacxin tuy thuoc vao tuoi ga va tnh trang
mien nhiem cua chung. Ga con c bao ho oi vi benh Reo la do khang the me truyen
sang cho ga con qua long o trng. e s truyen nay hieu qua, chng trnh tiem phong
ong bo vi ca vacxin song va chet c khuyen cao. vung ang nhiem benh, ga con co
the b nhiem benh ngay trong nhng tuan au. V the bat buoc phai tiem phong sm hn.
nhng vung nay, viec tiem phong phai c thc hien luc 5 ngay tuoi.
Tiem nhac lai luc 5-7 tuan tuoi va tiem nhac lai luc 9-11 tuan tuoi. oi vi ga giong, e
hoan tat lch tiem phong th phai tiem vi vacxin vo hoat Reo luc 18-22 tuan tuoi.
Hng dan s dung:
1. Co the s dung nc pha vacxin Nobilis Marek THV lyo e pha cho vacxin Reo.
Dung 200ml nc pha cho 1.000 lieu vacxin.
2. Dung cu, kim va bm tiem phai c tiet trung can than va khong co ton ong cac
chat sat trung.
3. Cho mot t nc pha vao lo vacxin va lac ky.
4. Rut vacxin a pha bang bm tiem, cho lai vao lo nc pha con lai, lac nhe. Rut nc
a pha e suc sach lo vacxin va cho tr lai vao lo nc pha.
5. Rut vacxin a pha hoan chnh vao bm tiem nh lng theo yeu cau 0,2ml/lieu va
tiem cho ga.
Lieu lng va cach s dung: Tiem vacxin 0,2ml/ga, tiem di da pha sau co.
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Lu y:
- Khong tiem cho ga trong vong 12 tuan trc khi ga e va trong thi ky e cua ga giong.
- Khong tron chung vacxin nay vi vacxin Marek hoac Gumboro song.
- Co gang giam toi a stress trong khi cung nh sau khi tiem phong
- Mot khi vacxin a pha phai s dung trong vong vai gi, tranh tiep xuc nhiet.
- Huy toan bo cac vo lo vacxin a s dung theo quy nh.
Bao quan: 2-80C, trong bong toi.
Qui cach: Lo vacxin cha 1.000 lieu
21. VACXIN NOBILIS REO INAC
(Vacxin sieu vi vo hoat bao ho ga phong nga benh viem khp truyen nhiem va hoi
chng giam hap thu)
Mo ta:
Vacxin cha 2 dong sieu vi Reo gia cam co ac tnh sinh mien dch cao, phong nga
benh do Reovirus ga. Sieu vi Reo c vo hoat bang formalin, vacxin dang nhu dau.
Ch nh:
Vacxin c s dung e bao ho ga phong nga viem khp va hoi chng kem hap thu.
Lch tiem phong:
Mac du Nobilis Reo INAC c dung e chung lan au cho ga moi la tuoi nhng mc
bao ho at c tot nhat khi ga a c tiem trc o vi vacxin song Nobilis Reo 1133. Co
the s dung vacxin ngay ca cho ga ang e cung khong gay thiet hai g so vi cac loai vacxin
khac. ga giong va ga hau b e thng pham chung lan au vi vacxin song Nobilis Reo
1133 t nhat 1 lan trc 12 tuan tuoi va sau o chung vi Nobilis Reo INAC 16-20 tuan tuoi.
Can tham khao y kien cua bac sy thu y tai a phng.
Tiem 0,5ml/ga, tiem bap (c ui hay ln) hoac tiem di da sau co ga.
Mien dch:
Khi viec tiem phong va tiem lan au vi vacxin song c thc hien ung cach, co the
phat hien c khang the sau o 1 tuan va at nh cao 3 tuan sau o. Nhn chung an ga
c chung vi Nobilis Reo INAC at mc bao ho tot va ong eu do co o sai khac gia
nhng ca the trong an rat nho. V the ga con t nhng an ga nay co khang the me truyen
sang u bao ho ga chong lai benh Reo.
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Phan ng khi tiem vacxin:
ga khoe manh khong co trieu chng g ang ke. Vai tuan sau khi tiem thay hi phong
nhe tai cho tiem. ieu nay khong ton hai g en te bao mo neu dung cu tiem phong c
sat trung ky.
Lu y:
- Trc khi tiem phong phai e vacxin at ngang nhiet o phong (15-250C).
- Neu ngi thc hien thao tac do vo y hay b ngi ben canh am kim phai th phan
ng tai cho tiem co the xay ra. Phai lien he bac s e xem xet va bao cao cho biet ay la
vacxin nhu dau.
22. VACXIN NOBILIS REO + IB + G + ND
(Vacxin vo hoat phoi hp phong 4 benh: benh do Reovirus, benh viem phe quan truyen
nhiem (IB), Gumboro va Newcastle (ND))
Mo ta:
Vacxin vo hoat phoi hp 4 benh: benh do Reovirus, benh viem phe quan truyen nhiem,
Gumboro va Newcastle.
Thanh phan:
- Virus benh viem phe quan truyen nhiem vo hoat chung M41
- Virus benh Newcastle vo hoat chung Clone 30
- Reovirus vo hoat chung 1733 va 2408
Cong thc: Vacxin nc trong dau
Ch nh: Dung cho ga
Vacxin dung e tiem phong nhac lai cho an giong nham bao ho an con phong benh
viem phe quan truyen nhiem, benh Newcastle, benh do Reovirus va benh Gumboro thong
qua khang the me truyen trong nhng tuan au sau khi n.
Nobilis Reo + IB + G + ND tiem cho ga giong muon nhat la 4 tuan trc khi ga bat au
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e d tnh. e vacxin cho hieu qua mien dch toi u, trc o ga phai c s dung vacxin
song phong 4 benh noi tren t nhat c 4 tuan.
Lieu lng: 0,5ml/ga
Cach s dung: Tiem bap (c ui hay c ln) hoac tiem di da vao na di co.
Thi gian ngng dung vacxin: khong
Quy cach: 500ml (1.000 lieu) trong moi chai thuy tinh hoac chai nha PET theo dc
ien chau Au.
Bao quan: 2-80C, tranh ong a.
Lu y:
- Ch tiem phong cho ga khoe
- e vacxin at nhiet o phong trc khi tiem
- S dung dung cu tiem vo trung
- Ch s dung vacxin trong vong 3 gi sau khi a m nap
- Khong tron lan vi cac vacxin khac.
- Huy vo chai va vacxin tha theo quy nh cua quoc gia.
- Neu chang may ngi tiem l tiem vao tay mnh hoac ngi ng ben canh, phan ng
cuc bo ni tiem co the xay ra. Can hoi y kien bac s va thong bao o la vacxin nhu dau.
Chong ch nh: Khong co.
23. VACXIN NOBILIS CORYZA
(Vacxin vo hoat bao ho ga phong nga benh Coryza)
Mo ta:
Vacxin cha vi khuan vo hoat Haemophilus paragallinarum typ huyet thanh A, B, C
trong dung dch nhu dau.
Ch nh:
Dung phong benh Coryza tren ga do Haemophilus paragallinarum.
Lch tiem phong:
- Tiem cho ga tren 5 tuan tuoi.
- e bao ho cho ga e, ga giong en 60 tuan tuoi can phai tiem nhac lai trc khi ga
len e vai tuan. Khoang thi gian gia hai lan tiem t nhat la 4 tuan.
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Lieu lng va cach dung:
Tiem lieu 0,5ml/ga, tiem di da pha sau co ga.
Phan ng khi tiem chung:
ga khoe manh khong co phan ng g ang ke. Vai tuan le sau khi tiem thay hi phong
nhe tai cho tiem. ieu nay cung khong gay ton thng mo neu tiem ung di da va sat
trung dung cu can than.
Lu y:
- Ch tiem cho ga khoe.
- Trc khi tiem phong phai e vacxin at nhiet o ngang nhiet o phong (15-250C).
- Lac ky lo vacxin trc khi s dung cung nh trong qua trnh tiem phong
- Neu ngi thc hien thao tac vo y hay b ngi ben canh am kim phai th phan ng
tai cho co the xay ra. Phai lien he bac s e xem xet va bao cho biet ay la vacxin nhu dau.
Bao quan: 2-80C, tranh ong a
Trnh bay: Lo vacxin 500ml cha 1.000 lieu.
24. VACXIN NOBILIS MG 6/85
(Vacxin song ong kho phong nga benh ng ho hap do Mycoplasma gallisepticum
tren gia cam)
Mo ta:
Nobilis MG 6/85 la vacxin song ong kho phong nga benh viem ng ho hap do
Mycoplasma gallisepticum. Moi lieu vacxin cha t nhat 106.9 CFUM Mycoplasma
gallisepticum song nhc oc dong MG /85.
Ap dung cach phun kh dung sau khi pha vacxin vi nc. Moi lieu t nhat 106.9 CFU.
Hng dan s dung:
- Phai xem xet nhieu yeu to e a ra mot chng trnh phong benh phu hp cho mot
trai rieng biet. e at hieu qua cao, phai ap dung phun vacxin di dang kh dung cho ga
khoe manh trong moi trng thch hp, quan ly tot. Mc o mien dch tuy thuoc rat nhieu
vao ky thuat phun vacxin va o phi nhiem.
95
- Ch dung nc sach, mat, khong co Chlorine (tot nhat la nc cat).
- M lo vacxin di mat nc.
- Lay nap nhom va nap cao su ra khoi lo
- Them mot lng nc can thiet cho viec phun vacxin (khoang 400ml cho 1.000 ga).
- Phun hat mn nho hn 20.
- Khong s dung bat ky thuoc sat trung nao hoac sa a tach b va ch s dung may
phun chuyen dung cho viec phun vacxin. Ra sach may phun sau moi lan s dung.
- Tat cac quat gio khi phun vacxin va cho quat chay lai sau o. ong ca tranh gio lua.
Chng trnh phong benh:
- Dung cho an ga t 6 tuan tuoi tr len.
- Thi iem toi u e dung tuy thuoc phan ln vao tnh hnh dch te a phng. V the
can co s khuyen cao cua bac sy thu y a phng.
Thi gian ngng s dung thuoc: khong.
Chong ch nh va canh bao:
- Khong dung vacxin nay trong vong 4 tuan trc khi ga e hay trong giai oan e.
- Toi thieu phai e khoang cach 2 tuan gia lan phun vacxin Nobilis MG 6/85 va cac
vacxin khac phong benh ng ho hap cho ga (v du vacxin phong benh Newcastle, benh
viem phe quan truyen nhiem v.v).
- Khong cha benh bang bat c loai thuoc khang khuan nao, ac biet la thuoc khang
Mycoplasma trong vong 5 ngay trc hoac 2 tuan sau khi phun vacxin.
- Khong dung cac vacxin khac trong vong 14 ngay.
Phan ng phu: Khong
Han ngng dung: Khong
Bao quan: nhiet o 2-80C, tranh anh sang.
Lu y:
- Ch dung cho ga khoe
- Nen phun tat ca ga trong chuong cung thi iem.
- Giam stress trong thi gian dung thuoc va trong thi gian co phan ng vacxin.
- Khong tron vacxin nay vi bat ky vacxin hay chat g khac.
- Phai s dung vacxin ngay khi a m lo.
- Khong pha loang lam giam lieu vacxin.
- Khong gi phan vacxin tha e dung lai, dung het sau khi m/pha lo vacxin.
- Khi phun vacxin, nen tranh e vacxin tiep xuc mat, tay hay quan ao.
96
- Tranh xa tam tay tre em.
Quy cach: Lo vacxin 1000 lieu.
25. VACXIN DCH TA VT NHC OC ONG KHO
(San xuat tren te bao hoac tren phoi trng)
ac tnh:
- La vacxin nhc oc, ong kho, san xuat t chung virus vacxin dch ta vt nhc oc
nuoi cay xoang nieu phoi trng vt hoac tren te bao x phoi ga.
- Vacxin an toan, tao mien dch nhanh va ben.
Ch nh:
- Moi lieu vacxin cha t nhat 103 EID50 (hoac 103 TCID50 oi vi vacxin dch ta vt san
xuat tren te bao) virus dch ta vt nhc oc.
Phng phap tiem vacxin:
- Vt con (di 2 tuan tuoi): tiem di da, pha vacxin bang nc sinh ly vo trung a lam
lanh. Lac tan eu.
- Vt tren 2 tuan tuoi: Tiem di da hoac tiem bap tht ln. Vacxin c pha vi nc
sinh ly lanh vo trung sao cho 0,5ml cha 1 lieu vacxin.
Lch tiem phong:
- oi vi vt nuoi tht: Tiem 2 lan
Lan 1: T en 5 ngay tuoi.
Lan 2: Sau lan tiem th nhat 2-3 tuan.
- oi vi vt e: Tiem 3 lan
Lan 1 va 2: Thc hien giong nh vt tht.
Lan 3: Vao luc 5 thang tuoi.
Va chung lai trc moi vu e.
(Tranh s dung vacxin trong giai oan thay long).
Dang trnh bay: Lo vacxin 200 lieu, 500 lieu va 1.000 lieu.
Bao quan: nhiet o 2-80C. Khong e vacxin vao ngan ong
Chu y:
97
- Ch tiem cho vt khoe
- Nen tiem cho tat ca vt trong chuong cung thi iem.
- Giam stress trong thi gian tiem phong va trong thi gian co phan ng vacxin.
- Khong tron vacxin nay vi bat ky vacxin hay chat g khac.
- Phai s dung vacxin ngay khi a m lo.
- Khong pha loang lam giam lieu vacxin.
- Khong gi phan vacxin tha e dung lai, dung het sau khi m/pha lo vacxin.
- Khi phun vacxin, nen tranh e vacxin tiep xuc mat, tay hay quan ao.
- Tranh xa tam tay tre em.
- Sau khi pha lo vacxin phai c gi trong nc a va dung trong vong 2-3 gi, dung
xong phai ngam chai vacxin vao chat sat trung hay luoc soi trc khi bo i.
26. VACXIN DCH TA VT TE BAO
Mo ta:
- Vacxin ong kho nhc oc dang te bao.
- Moi lieu vacxin cha t nhat 104 TCID50 virus dch ta vt nhc oc
- Chat on nh: sa khong kem
Cong dung:
Vacxin dung phong benh dch ta cho vt, ngong va vt xiem khoe manh t 2 tuan tuoi tr len.
Lieu dung va cach s dung:
- Tiem bap tht (c ln)
- Vacxin c pha loang vi nc sinh ly man vo trung a c lam mat, sao cho 0,5ml
dung dch tiem cha 1 lieu vacxin.
- Sau khi pha, vacxin phai c gi trong nc a, tranh anh sang mat tri va phai dung
het trong vong 4 gi.
Lch tiem phong:
- oi vi vt nuoi tht: tiem 2 lan:
Lan 1: 3-5 ngay tuoi
Lan 2: 2-3 tuan sau khi tiem lan 1.
- oi vi vt e: lan 1 va lan 2 nh vt tht
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Lan 3 vao luc 5 thang tuoi.
Va tiem lai trc moi vu e sau.
(Tranh dung vacxin trong giai oan thay long).
Chong ch nh: Khong dung cho vt om yeu.
Thi gian ngng s dung thuoc: 0 ngay.
Bao quan:
- Nhiet o bao quan t 2-80C.
- Khong c lam ong a vacxin.
- Trong qua trnh van chuyen phai s dung xe lanh chuyen dung hoac gi vacxin trong
thung xop co a lanh (hoac a kho), tranh nong va tranh anh sang trc tiep.
- Han dung 18 thang.
27. VACXIN TU HUYET TRUNG VO HOAT
ac tnh:
- La vacxin vo hoat, che t vi khuan Pasteurella multocida serotyp A:1
- Vacxin an toan, tao mien dch tot.
- Moi 1ml vacxin cha t nhat 1010 te bao vi khuan Pasteurella multocida serotyp A:1.
Ch nh: Dung gay mien dch chu ong phong benh tu huyet trung cho ga, vt, ngan va
ngong khoe manh.
Cach s dung:
- Lay vacxin ra khoi ni bao quan, e ni mat khoang 1 gi va lac ky trc khi dung.
- Tiem di da co hoac c cua gia cam. (Chu y s dung het vacxin trong ngay).
Lieu dung:
- Gia cam t 25 ngay va di 2 thang tuoi: lieu 0,5ml/con.
- Gia cam t 2 thang tuoi tr len: lieu 1ml/con.
Dang trnh bay: Chai: 25ml cha 25 lieu, 50ml cha 50 lieu.
Bao quan: 2-80C. Khong e vacxin vao ngan ong
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28. VACXIN TU HUYET TRUNG GIA CAM NHU DAU VO HOAT
ac tnh:
- La vacxin vo hoat c nhu hoa, che t vi khuan Pasteurella multocida serotyp A:1.
Vacxin nay co mau trang sa ong nhat.
- Moi 1ml vacxin cha t nhat 1010 te bao vi khuan Pasteurella multocida serotyp A:1.
- Vacxin an toan, tao mien dch cao va ben khi tiem phong cho gia cam.
Ch nh: Dung gay mien dch chu ong phong benh tu huyet trung cho ga, vt, ngan
va ngong khoe manh.
Lieu dung va cach dung:
- Tiem di da co hoac c cua gia cam vi lieu nh sau:
+ Gia cam t 25 ngay va di 2 thang tuoi: lieu 0,5ml/con.
+ Gia cam t 2 thang tuoi tr len: lieu 1ml/con.
- Chu y: s dung het vacxin trong ngay.
Dang trnh bay: Chai 50 lieu.
Bao quan: 2-80C. Khong e vacxin vao ngan ong
IV. VACXIN DUNG CHO CAC GIA SUC KHAC
1. VACXIN XUAT HUYET THO
Thanh phan:
- Virus gay benh xuat huyet tho truyen nhiem Calicivirus a c vo hoat bang formalin.
- Chat bo tr: keo phen.
Hng dan s dung:
- Ch nh: Dung tiem phong cho tho khoe manh t 2 thang tuoi tr len e phong benh
xuat huyet truyen nhiem (RHD) do Calicivirus gay ra.
- Cach s dung: Vacxin c tiem di da hoac tiem bap tht.
- Lch tiem phong:
+ Tiem phong lan au: 60 ngay tuoi (2 thang). Neu trong vung co benh xuat huyet tho
lu hanh, hoac trong vung co nguy c nhiem benh cao co the tiem phong vacxin cho tho
luc 45 ngay.
+ Tiem nhac lai: c 6 thang sau o tiem nhac lai mot lan
100
Chong ch nh: khong dung cho tho ang b benh.
Chu y:
- Lac ky trc khi dung.
- Bm tiem va kim tiem phai c tiet trung trc va sau khi s dung.
- Dung kim vo trung e lay thuoc. Tranh s dung mot kim tiem cho nhieu tho.
- Khong c lam ong a vacxin.
- Trong qua trnh van chuyen phai gi trong thung xop co a lanh, tranh nong va anh
sang mat tri chieu trc tiep.
ong goi: Chai 20 lieu va 50 lieu.
Bao quan: 2-80C.
Han dung: 12 thang ke t ngay san xuat
2. VACXIN PHONG DAI RABISIN
ac iem:
- Vacxin che t virus ai cng oc nuoi cay tren moi trng te bao, a giet chet bang
hoa chat, co mau trang, hi uc.
- Vacxin an toan, khong gay phan ng cuc bo va toan than.
- Vacxin tao mien dch on nh cho cho, keo dai trong 3 nam.
Hng dan s dung:
- Vacxin dung tiem phong benh dai cho cho khoe manh t 2 thang tuoi tr len.
- Vacxin c tiem di da trong ui vi lieu 01ml.
Bao quan:
- Gi vacxin nhiet o 40C en 100C, co the bao quan 12 thang.
- Khong e vacxin trong lanh am.
Trnh bay: Moi lo ong 01 lieu
Hang san xuat: Hang Rhon-Pulence (Phap)
3. VACXIN PHONG 4 BENH CHO CHO
ac iem:
- La hon hp 4 loai vacxin e phong 4 benh cho cho, bao gom 3 loai vacxin virus nhc
101
oc phong benh Care (benh sai sot), benh viem gan do virus va benh viem ruot do virus
Parvo. Va mot loai vacxin chet phong benh Leptospirosis che t 2 chung xoan trung:
Leptospira icterohaemorhagiae va L.canicola.
- Vacxin nhap t Hang Rhon - Pulence (Phap) co ten la vacxin Tetradog va nhap t hang
Intervet (Ha Lan) co ten la Nobivac. Tnh nang 2 loai vacxin nay hoan toan giong nhau.
- Vacxin co o an toan cao, rat t gay phan ng.
- Sau khi tiem, cho c mien dch vi 4 benh tren, keo dai 12 thang.
- Moi lieu vacxin gom 2 lo, 1 lo cha 3 chung virus nhc oc a ong kho: Care, Parvo
va viem gan va 01 lo cha dung dch vacxin chet Lepospirosis. Khi tiem se hoa 2 lo vi
nhau roi tiem ngay.
Hng dan s dung:
- Dung tiem phong 4 benh cho cho khoe manh t 2 thang tuoi tr len. Co the tiem cho
cho t 6 tuan tuoi.
- Tiem di da trong ui.
- Cho con 2 thang tuoi c tiem lan au, sau 4 tuan tiem lan th 2, sau o c moi nam
tiem nhac lai mot lan, am bao mien dch tot.
Lieu tiem: Hai lo pha vi nhau thanh 1 lieu 2ml tiem cho mot con cho.
Bao quan:
- Gi vacxin nhiet o 40C en 120C, bao quan c 12 thang.
- Khong c e trong lanh am, khong e anh sang mat tri chieu vao.
Trnh bay:
- Hop 10 lieu gom 10 hop nho, co ong tiem san.
- Hop 100 lieu, khong co ong tiem nhng moi lieu gom 2 lo nho, khi tiem se pha lan.
Hang san xuat: Hang Rhon-Pulence (Phap).
Hang Intervet (Ha Lan)
V. VACXIN PHONG BENH CHO TOM, CA VA VACXIN KY SINH TRUNG
nc ta, v nhieu ly do, cac vacxin cho tom, ca va vacxin phong chong benh ky sinh
trung cha c s dung. Tuy nhien, trong cuon sach nay chung toi cung gii thieu e oc
gia co them mot so thong tin.
1. VACXIN PHONG BENH CHO CA VA TOM
Trong nuoi trong thuy san vacxin cha c s dung rong rai v:
- Ca thng c nuoi vi so lng ln, chu ky nuoi lai ngan (3 - 6 thang).
- Viec tiem phong cho ca rat kho thc hien.
- Viec che tao vacxin thuy san kho khan va gia thanh cao.
102
1. oi vi ca:
hau het cac vung sinh thai tren the gii, trong am ca nc ngot co lu hanh mot benh
truyen nhiem nguy hiem ma nguyen nhan la mot loai vi khuan (Aeromonas Chlorphila)
gay ra hoi chng loet o da, bong vay, lam cho ca chet hang loat.
mot so nc nh Nhat Ban, Australia, My ngi ta a nghien cu che tao thanh cong
mot vacxin chet vi cac nguyen ly va phng phap che tao vacxin chet tng t nh trong
che tao vacxin chet phong benh cho gia suc, gia cam. Vacxin do Trung tam thu y thuoc
Vien SCIRO (Australia) san xuat co the at hieu gia bao ho 80 - 85%, phong benh loet o
da cho mot so loai ca co vay nh: ca chep, ca tram co, ca me
2. oi vi tom:
Tom nuoi va tom song t nhien vung nc l ( Nhat Ban, Philippin, Indonesia, Viet
Nam) thng mac mot so benh truyen nhiem, trong o ac biet la benh om trang do mot
loai virus gay ra. Ngi ta a nghien cu mot loai vacxin tai to hp t virus gay benh om
trang. Vacxin a thanh cong trong phong th nghiem Nhat Ban va My nhng cha c
ng dung trong san xuat do at o va kho khan trong viec ap dung.
2. VACXIN PHONG CHONG KY SINH TRUNG
Cac vacxin phong chong ky sinh trung a c nghien cu, che tao cung da tren
nguyen ly va phng phap che tao vacxin phong chong cac benh truyen nhiem. Nhieu
loai vacxin ky sinh trung a c nghien cu che tao nhng v vacxin ky sinh trung kho
san xuat, oi hoi trang thiet b hien ai va ong bo va chi ph san xuat rat ton kem nen gia
thanh cao. Mat khac, cac loai vacxin ky sinh trung tao mien dch ap ng khong on nh,
thi gian mien dch ngan. Do vay, hien nay ch co mot so t vacxin ky sinh trung co hieu
lc cao mi c s dung.
- Th du 1: Vacxin nhc oc phong benh giun phoi trau bo do giun tron (Dictyocaulus
viviparus). Ngi ta nuoi cay tao ra au trung giun phoi thi ky 3 (L3) roi chieu tia a hoac
lam cho au trung mat oc lc nhng tiem cho bo van tao c mien dch phong benh giun
phoi. Vacxin a c nghien cu va s dung lan au Ba Lan t cuoi nhng nam 70 va
nhng nam 80 cua the ky XX. Hieu gia bao ho cho bo at 70%.
- Th du 2: Vacxin phong benh cau trung Precovac c san xuat t noan nang cau trung
Eimeria preacoc, chieu tia hoac , lam mat oc lc cua noan nang, tao ra vacxin nhc
oc phong benh cho ga bang cach cho an. Ga c an vacxin tao c ap ng mien dch
chong cac loai cau trung Eimeria, khong co trieu chng a long ra mau (trieu chng ac
trng cua cau trung), ga tang trong nhanh, ty le chet thap nhng phan thai ra van con noan
nang cau trung. ay la loai vacxin c My, Canada san xuat. Gia thanh vacxin cao nen
cha c dung rong rai tren the gii.
- Th du 3: Vacxin tai to hp phong chong ve bo (Boophilus). Vacxin c che tao bang
cach nghien Boophilus microplus trng thanh, roi dung phng phap cong nghe sinh hoc
phan lap cac khang nguyen t dch nghien ve, thay c 243 khang nguyen trong o la
chon c 4 khang nguyen nam tren vach da day ve. Ngi ta dung 4 khang nguyen nay
ghep lai, che tao ra vacxin phong chong ve bo. Khi tiem vacxin cho bo, sau 3 tuan bo co
ap ng mien dch trong mau. Ve hut mau bo co khang the th da day se b khang the pha
huy va chet. Hieu lc bao ho cua vacxin at 93%. Co the noi hieu lc rat cao, cung tng
t nh vacxin phong cac benh truyen nhiem. Vacxin nay c nghien cu che tao va s
dung Australia t nhng nam 90, phong chong c ve Boophilus microplus, tc la phong
c benh Le dang trung do Babesia bigemina bo. Vacxin co gia thanh cao nen ch mi
c s dung cac nc phat trien, nuoi bo vi quy mo ln.
103
PHU LUC
CAC VAN BAN QUY NH PHONG CHONG
MOT SO BENH NGUY HIEM
BO NONG NGHIEP CONG HOA XA HOI CHU NGHA VIET NAM

VA PHAT TRIEN NONG THON oc lap - T do - Hanh phuc
******** ********
So: 38/2006/Q-BNN Ha Noi, ngay 16 thang 5 nam 2006
QUYET NH
V/V BAN HANH QUY NH PHONG CHONG
BENH L MOM LONG MONG GIA SUC
BO TRNG BO NONG NGHIEP VA PHAT TRIEN NONG THON
Can c Phap lenh Thu y ban hanh ngay 29/4/2004;

Can c Ngh nh so 33/2005/N - CP ngay 15/3/2005 cua Chnh phu Quy nh chi tiet thi hanh
mot so ieu cua Phap lenh Thu y;
Can c Ngh nh so 86/2003/N - CP ngay 18 thang 7 nam 2003 cua Chnh phu quy nh chc
nang, nhiem vu, quyen han va c cau to chc cua Bo Nong nghiep va Phat trien nong thon;
Theo e ngh cua Cuc trng Cuc Thu y.
QUYET NH
ieu 1. Ban hanh kem theo Quyet nh nay Quy nh ve phong chong benh L mom long
mong gia suc.
ieu 2. Quyet nh nay co hieu lc sau 15 ngay, ke t ngay ang Cong bao va thay the Quyet
nh so 54/2001/Q/BNN - TY ngay 11 thang 5 nam 2001 cua Bo Nong nghiep va Phat trien nong
thon ve Ban hanh quy nh ve phong chong benh l mom long mong gia suc.
ieu 3. Cuc trng Cuc Thu y co nhiem vu hng dan chi tiet viec thi hanh ban quy nh nay.
ieu 4. Chanh Van phong Bo, Cuc trng Cuc Thu y, Thu trng cac n v co lien quan va
Giam oc S Nong nghiep va Phat trien nong thon cac tnh, thanh pho trc thuoc Trung ng chu
trach nhiem thi hanh Quyet nh nay./.
Ni nhan:
KT. BO TRNG
- Nh ieu 4;
- Van phong Chnh phu; TH TRNG
- Cong bao VPCP;
- Bo trng, cac Th trng Bo NN & PTNT;
- Uy ban nhan dan cac tnh, thanh pho;
- Cuc Kiem tra van ban (Bo T phap); Bui Ba Bong
- Chi cuc Thu y cac tnh, thanh pho;
- Lu VT, PC.
104
QUY NH
VE PHONG CHONG BENH L MOM LONG MONG GIA SUC
(Ban hanh theo Quyet nh so: 38/2006/Q-BNN ngay 16/5/2006 cua Bo trng Bo Nong
nghiep va Phat trien Nong thon)
Chng 1
NHNG QUY NH CHUNG
ieu 1. Pham v ieu chnh va oi tng ap dung
Quy nh nay ap dung oi vi to chc, ca nhan Viet Nam, to chc, ca nhan nc ngoai trong
lanh tho Viet Nam co hoat ong ve chan nuoi, buon ban, giet mo, van chuyen, kinh doanh ong vat
va san pham ong vat cam nhiem oi vi benh L mom long mong (LMLM).
ieu 2. Giai thch t ng
Trong quy nh nay, cac t ng di ay c hieu nh sau:
1.O dch LMLM la ni co mot hoac nhieu gia suc mac benh LMLM.
2. Vung dch la mot hoac nhieu thon, ban, ap (sau ay goi la thon), xa, huyen co dch.
3. Vung khong che (con goi la vung b dch uy hiep) la cac xa tiep giap vi xa co dch va cac
thon cha co dch trong xa o; cac xa tiep giap vi ng bien gii cua Viet Nam.
4. Vung em la vung tiep giap ben ngoai vung khong che trong pham vi 5 km tnh t chu vi
vung khong che.
5. ong vat cam nhiem oi vi benh LMLM la cac loai ong vat co mong guoc chan nh: trau,
bo, ln, de, cu, hu, nai...
6. Vung nguy c cao la cac thon xung quanh ch buon ban gia suc va ni giet mo gia suc; cac
xa co iem trung chuyen, tap ket gia suc; cac th tran, th t co ng quoc lo i qua.
ieu 3. ac iem chung cua benh L mom long mong gia suc
1. Benh L mom long mong gia suc la benh truyen nhiem lay lan manh, gay ra bi 7 typ vi rut:
A, O, C, Asia1, SAT1, SAT2, SAT3 vi hn 60 phan typ. khu vc ong Nam A thng thay 3 type
la O, A va Asia1. Viet Nam a phat hien typ O, typ A va Asia1. Benh LMLM lay lan qua tiep
xuc gia ong vat khoe vi ong vat, san pham ong vat va thc an, nc uong, chat thai, dung cu,
phng tien van chuyen co mang mam benh, lay lan qua ng ho hap; benh lay lan t vung nay
sang vung khac, lay t nc nay sang nc khac qua bien gii theo ng van chuyen ong vat, san
pham ong vat dang ti song (ke ca tht p ong, da xng, sng, mong, sa..).
2. ong vat mac benh LMLM la cac loai mong guoc chan nh: trau, bo, ln, de, cu, hu, nai...
Thi ky u benh thng t 2 - 5 ngay, nhieu nhat la 21 ngay. Khi benh co trieu chng th trong
hai, ba ngay au sot cao tren 400C, kem an hoac bo an, mieng gia suc chay nhieu nc bot; b viem
dang mun nc li, li, vanh mui, vanh mong, ke mong, au vu. Khi mun nc v ra lam l loet
mom va de lam long mong, nhat la ln.
Sau khi phat benh 10 - 15 ngay, con vat co the khoi ve trieu chng lam sang nhng mam benh
van ton tai trong con vat (3 - 4 tuan oi vi ln, 2 - 3 nam oi vi trau bo, 9 thang oi vi cu, 4
thang oi vi de) va thai mam benh ra moi trng lam phat sinh va lay lan dch benh.
105
Benh khong co thuoc cha ac hieu, ch co vac xin phong benh. Benh LMLM c To chc
Thu y the gii (OIE) xep au tien bang A (gom cac benh truyen nhiem nguy hiem nhat cho chan
nuoi va han che thng mai oi vi ong vat, san pham ong vat cung nh nong san noi chung).
3. Vi rut LMLM de b diet bi anh nang mat tri, nhiet o cao (nh un soi 1000C), cac chat co
o toan cao (pH 3) va cac chat kiem manh nh xut (pH 9). Vi rut song nhieu ngay trong cac chat
thai hu c chuong nuoi, cac chat co o kiem nhe (pH t 7,2-7,8). Trong tht p ong, vi rut ton
tai sau nhieu thang.
Chng 2
PHONG BENH L MOM LONG MONG
ieu 4. Tuyen truyen benh LMLM va cach phong chong

1. Cuc Thu y xay dng noi dung chng trnh tuyen truyen phong chong benh LMLM va hng
dan cac Chi cuc Thu y trien khai chng trnh tuyen truyen a phng.
2. Uy ban nhan dan cac cap ch ao viec thc hien thong tin tuyen truyen tai a phng mnh
theo noi dung cua cac c quan thu y.
3. Cac c quan thong tin ai chung, c quan, n v to chc tuyen truyen pho bien kien thc ve
tnh chat nguy hiem va bien phap phong chong benh LMLM ti tng ho gia nh va cong ong.
4. Tuyen truyen, van ong ngi chan nuoi trong tng thon ky cam ket thc hien "5 khong":
a) Khong giau dch;
b) Khong mua gia suc mac benh, san pham gia suc mac benh a ve thon;
c) Khong ban chay gia suc mac benh;
d) Khong tha rong, khong t van chuyen gia suc b mac benh LMLM ra khoi vung dch;
) Khong vt xac gia suc nghi mac benh LMLM ba bai.
ieu 5. Trach nhiem cua cac c quan trong viec giam sat phat hien benh
1. Cuc Thu y co trach nhiem
a) Hng dan cac a phng noi dung giam sat dch benh;
b) Tap hp so lieu dch te t cac a phng;
c) Phoi hp vi Vien Thu y to chc chan oan benh, giam sat s lu hanh cua vi rut; xay dng
ban o dch te ve benh LMLM hang nam;
d) To chc cac oan kiem tra, giam sat dch benh trong ca nc.
2. Chi cuc Thu y cac tnh, thanh pho trc thuoc Trung ng (sau ay goi chung la cap tnh) co
trach nhiem
a) Thanh lap to chuyen trach giam sat benh LMLM co t nhat 2 can bo;
b) Hng dan cac quan, huyen, th xa, thanh pho thuoc tnh (sau ay goi chung la cap huyen)
trien khai cac hoat ong ieu tra, giam sat phat hien dch benh;
c) To chc lay mau e chan oan theo hng dan cua Cuc Thu y.
3. Thu y cap huyen (Tram Thu y) co trach nhiem
a) Phan cong can bo thng xuyen theo doi giam sat phat hien dch benh;
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b) Khi nhan c bao cao gia suc nghi mac benh LMLM, tien hanh xac minh ngay va bao cao
kp thi len cap tren.
4. cap xa
a) Uy ban nhan dan xa phan cong nhan vien thu y theo doi giam sat dch benh ti tan thon;
b) Co so, sach theo doi an gia suc, dien bien tnh hnh dch benh, ket qua tiem phong cac thon;
c) Khi co chu vat nuoi hoac thu y t nhan bao cao co gia suc nghi mac benh LMLM, nhan vien
thu y kiem tra ngay va bao cao cho Tram thu y cap huyen.
5. thon
a) Trng thon, thu y vien chu trach nhiem giam sat dch benh LMLM en tan ho gia nh, c
s chan nuoi trong thon;
b) Thong bao tnh hnh dch, bao cao dch benh len xa.
6. Chu vat nuoi
Khi nghi ng gia suc mac benh, chu vat nuoi phai bao ngay cho trng thon hoac nhan vien thu y.
ieu 6. Ve sinh phong benh
Cac c s chan nuoi, cac ho chan nuoi phai thc hien cac bien phap e am bao an toan dch
benh, phong dch
1. Khu chan nuoi
a) Phai co hang rao, ranh gii e cach ly vi ben ngoai, loi ra vao phai co ho sat trung;
b) Thng xuyen thc hien ve sinh chuong trai, bai chan tha, dung cu chan nuoi, phng tien
van chuyen; diet loai gam nham nh chuot...
2. Con giong
Con giong a vao chan nuoi phai khoe manh, co nguon goc ro rang, a c tiem phong benh
LMLM, trc khi nhap an phai c nuoi cach ly 21 ngay.
3. Thc an, nc uong
a) Thc an chan nuoi phai u tieu chuan ve sinh thu y, khong gay hai cho ong vat va ngi
s dung san pham ong vat. Thc an t che, tan dung phai c x ly nhiet (1000C) trc khi cho
ong vat an;
b) Nc s dung trong chan nuoi, che bien thc an chan nuoi phai bao am ve sinh thu y.
4. Hoa chat kh trung
Co the s dung mot trong cac loai hoa chat sau: xut 2%, formol 2%, crezin 5%, nc voi 20%
hoac voi bot va mot so hoa chat kh trung khac theo hng dan cua nha san xuat.
5. oi vi con ngi
Ngi chan nuoi, khach tham quan, nhan vien thu y trc khi ra vao khu vc chan nuoi phai
c ve sinh, kh trung va s dung trang b bao ho.
ieu 7. Tiem vac xin phong benh
1. Vung tiem phong
Vung c tiem vac xin phong benh bao gom: vung khong che, vung em, vung co dch xay ra
trong thi gian 2 nam gan ay, vung co nguy c cao.
2. oi tng tiem phong
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oi tng tiem phong bao gom:
a) Trau, bo, de, cu, hu, nai, ln nai, ln c giong tren a ban vung tiem phong;
b) Tat ca ong vat cam nhiem khi a ra khoi tnh th phai tiem phong ke ca ong vat o nam ngoai
vung tiem phong qui nh tren (phai sau khi tiem 14 ngay hoac a c tiem phong va con mien dch).
3. Thi gian tiem phong
a) Tiem phong hai lan trong mot nam, lan th nhat cach lan th hai sau thang; lan th nhat tiem
vao thang 3-4, lan th hai tiem vao thang 9-10;
b) Lieu lng, ng tiem, quy trnh s dung vac xin theo hng dan cua Cuc Thu y va nha san xuat.
4. Kinh ph tiem phong
Kinh ph tiem phong vac xin phong benh theo quy nh cua Chnh phu.
ieu 8. Kiem dch van chuyen
1. Van chuyen trong nc
a) Chu tch Uy ban nhan dan tnh quyet nh thanh lap tram, chot kiem dch tam thi tai au moi
giao thong theo e ngh cua S Nong nghiep va Phat trien nong thon khi cac tnh lien ke co dch;
b) To chc thu gi, tieu huy gia suc mac benh hoac gia suc van chuyen vao tnh khong co giay
chng nhan kiem dch hp le; chu gia suc khong c boi thng va phai chu x phat hanh chnh,
chu chi ph tieu huy;
c) C quan Thu y chu trach nhiem thc hien viec kiem dch tai goc va cap giay chng nhan
kiem dch theo quy nh, neu vi pham se b x ly theo quy nh cua phap luat.
2. Van chuyen qua bien gii
a) Chu tch Uy ban nhan dan cac tnh bien gii ch ao cac cap, cac nganh tang cng cong tac kiem
tra, kiem soat, ngan chan, x ly ong vat cam nhiem va san pham cua chung nhap lau vao trong nc;
b) Uy ban nhan dan tnh quyet nh thanh lap cac chot kiem dch tai cac xa bien gii;
c) Kh trung moi phng tien van chuyen qua ca khau.
Chng 3
CHONG DCH L MOM LONG MONG
ieu 9. Cong bo dch
1. Khi co u ieu kien cong bo dch theo quy nh tai ieu 17 cua Phap lenh Thu y th Chu tch
Uy ban nhan dan cap tnh ra quyet nh cong bo dch.
2. Quy nh ve pham vi cong bo dch nh sau:
a) Dch xuat hien 1 thon tr len th cong bo xa co dch;
b) Dch xuat hien 2 xa tr len th cong bo huyen co dch;
c) Dch xuat hien 2 huyen tr len th cong bo tnh co dch;
3. C quan thu y co tham quyen thong bao ket qua xet nghiem benh tai a phng co dch.
108
ieu 10. X ly o dch
1. Cach ly va nuoi nhot gia suc mac benh
Chu nuoi gia suc khi phat hien gia suc nhiem benh phai nuoi cach ly va bao ngay cho trng
thon hoac nhan vien thu y.
2. Xac minh va chan oan
Khi nhan c thong bao, trong pham vi mot ngay can bo thu y huyen phai tien hanh xac minh
va lay mau chan oan benh.
3. Chu tch Uy ban nhan dan cap xa co trach nhiem
a) Ch ao trng thon va nhan vien thu y kiem tra, giam sat chu nuoi gia suc thc hien cach
ly gia suc mac benh vi gia suc khoe, nhot trau, bo, ln, de, cu tai chuong hoac ni co nh; giup
can bo thu y huyen lay mau benh pham; thong ke so lng, loai gia suc mac benh, so ho gia nh
co gia suc mac benh, tong an gia suc cam nhiem trong thon.
b) Lap chot kiem dch ong vat tam thi tren cac truc ng giao thong chnh ra vao vung dch
va vung khong che vi s tham gia cua lc lng thu y, cong an, dan quan t ve trc 24/24 gi
nham ngan chan khong a ong vat, san pham ong vat ra ngoai vung dch. at bien bao khu vc
co dch, hng dan tranh i qua vung dch. To chc phun kh trung cac phng tien van chuyen t
vung dch i ra ngoai.
c) Thc hien tieu huy gia suc mac benh trong vung dch
- oi tng tieu huy
+ Tieu huy bat buoc toan bo so ln, de, cu, hu, nai trong cung mot o chuong neu trong o chuong
o co con mac benh vi trieu chng lam sang ien hnh ma khong phai ch ket qua xet nghiem.
Trng hp con nghi ng phai nuoi cach ly ch ket qua xet nghiem, neu ket qua dng tnh th tieu
huy. Viec tieu huy gia suc benh phai thc hien theo hng dan va giam sat cua c quan thu y;
+ Tieu huy bat buoc trau bo mac benh trong cac trng hp sau:
* Trau, bo mac benh trong o dch xuat hien lan au tien tai thon;
* Trau, bo mac benh vi typ vi rut LMLM mi hoac typ vi rut a lau khong xuat hien tren
a ban tnh.
+ oi vi trau, bo khong thuoc dien neu tren th khuyen khch tieu huy hoac co the nuoi gi
nhng phai quan ly chat che nh sau:
* anh dau bang bam tai va co so sach theo doi theo hng dan cua Cuc Thu y;
* Nuoi cach ly vi an gia suc cha mac benh va theo doi sc khoe thng xuyen, tang cng
che o cham soc, nuoi dng;
* c giet mo tieu thu tai xa theo hng dan cua thu y;
* c phep van chuyen ra khoi xa e tieu thu sau hai nam tnh t ngay con vat khoi trieu
chng lam sang.
- Cach tieu huy
+ ot: ao ho, cho gia suc vao ho va ot bang cui, than, xang, dau. Sau o lap at va nen chat;
+ Chon: ao ho co kch thc tuy theo so lng gia suc can tieu huy, cho gia suc mac benh
xuong ho, phun thuoc sat trung hoac o voi bot len be mat gia suc va lap at. Khoang cach t be
mat gia suc chon en mat ho chon toi thieu la 1 met, nen at tren be mat that chat;
+ a iem ot, chon c ghi vao so va tren ban o cua xa e lu gi.
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) Ve sinh, tieu oc kh trung
- Tai o dch
+ Ve sinh c gii: Thu gom chat thai, phan rac ni nuoi nhot gia suc b benh e ot hoac chon;
ra nen chuong, dung cu chan nuoi bang nc xa phong. Cong viec nay do chu gia suc thc hien;
+ Ve sinh hoa chat: Sau khi ve sinh c gii, e kho va tien hanh phun hoa chat kh trung thch
hp vi tng oi tng. Cong viec nay do oi chong dch cua xa thc hien.
- Vung xung quanh o dch
+ Chu chan nuoi gia suc phai to chc ve sinh c gii chuong trai, dung cu chan nuoi, tranh tiep
xuc vi vung co dch;
+ oi chong dch cua xa to chc phun thuoc kh trung khu vc chan nuoi, chuong trai, rac voi
bot ng lang, ngo xom.
e) Tiem phong vac xin bao vay
- To chc tiem phong vac xin cho trau, bo, de, cu, ln nai, ln c giong vung khong che,
tiem t ngoai vao trong. Sau khi tiem c 14 ngay, tien hanh tiem cho ong vat cam nhiem vung
dch nhng khong mac benh; khong tiem cho gia suc a khoi trieu chng lam sang (trong trng
hp khong tieu huy).
- Huy ong lc lng tiem phong va ho tr tiem phong; ngi trc tiep tham gia tiem phong phai
la nhan vien thu y hoac ngi a qua tap huan.
- Chi Cuc Thu y tnh hng dan, quan ly va giam sat viec tiem phong.
4. Chu tch Uy ban nhan dan cap huyen c Uy ban nhan dan tnh uy quyen ra quyet nh tieu
huy gia suc mac benh da tren chnh sach ho tr cua Chnh phu sau khi co e ngh bang van ban
cua Chi cuc Thu y.
5. Khong c buon ban gia suc cam nhiem vi benh; khong to chc trien lam, tham quan, vui
chi trong vung co dch.
6. Che o bao cao: trong thi gian co dch, Uy ban nhan dan cap di co trach nhiem bao cao
hang ngay len Uy ban nhan dan cap tren, c quan thu y cap di co trach nhiem bao cao hang ngay
len c quan thu y cap tren cho en khi co quyet nh cong bo het dch;
Ngay khi xay ra dch, Chi cuc Thu y phai thong bao ngay cho Chi cuc Thu y cac tnh, thanh pho
lan can biet e chu ong phong, chong benh.
ieu 11. Kiem soat van chuyen
Chu tch Uy ban nhan dan cap tnh ch ao chnh quyen a phng cac cap, cac nganh thc
hien cac nhiem vu cu the sau:
1. Xac nh thon, xa, huyen co dch e khoanh vung o dch va lap cac chot kiem dch tam thi
co ngi trc 24/24 gi, co bien bao, hng dan giao thong; ngan cam viec a gia suc va san pham
cua chung ra ngoai vung dch. Tai cac chot nay phai co phng tien va chat sat trung e x ly moi
oi tng ra khoi vung dch;
2. Khong c van chuyen gia suc cam nhiem vi benh LMLM va san pham cua chung ra khoi
vung dch va vung khong che;
3. Gia suc khoe manh, khong mang mam benh trong vung em th c phep lu thong trong
pham vi tnh.
ieu 12. Cong bo het dch
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Khi co u ieu kien cong bo het dch theo quy nh tai ieu 21 cua Phap lenh Thu y th Chu tch
Uy ban nhan dan cap tnh ra quyet nh cong bo het dch.
Chng 4
TO CHC THC HIEN
ieu 13. Trach nhiem cua c quan quan ly nha nc Trung ng trong phong chong
benh LMLM
1. Bo Nong nghiep va Phat trien nong thon
a) Trnh Thu tng Chnh phu phe duyet Chng trnh quoc gia khong che va thanh toan benh
LMLM qua cac giai oan va ch ao, hng dan, kiem tra thc hien Chng trnh trong pham vi ca nc;
b) Chu tr phoi hp vi cac Bo, Nganh lien quan trnh Thu tng Chnh phu ban hanh cac chnh
sach lien quan en cong tac phong chong benh LMLM;
c) Thanh lap Ban ch ao phong chong benh LMLM cua Bo.
2. Cac Bo, Nganh co lien quan
Thc hien cac nhiem vu c Thu tng Chnh phu phan cong va phoi hp vi Bo Nong nghiep
va Phat trien nong thon nham tap trung nguon lc phuc vu phong chong benh LMLM.
3. Cuc Thu y
a) Tham mu cho Bo Nong nghiep va Phat trien nong thon trong viec xay dng chng trnh
quoc gia khong che va thanh toan benh LMLM va cac chnh sach lien quan;
b) Xay dng ke hoach phong chong benh LMLM hang nam va trien khai to chc thc hien,
thanh tra, kiem tra tren pham vi toan quoc;
c) Hng dan cac bien phap phong chong dch benh LMLM.
ieu 14. Trach nhiem cua c quan quan ly nha nc a phng trong phong, chong
benh LMLM
1. Cap tnh
a) Uy ban nhan dan tnh
- Thanh lap Ban ch ao phong chong dch LMLM cua tnh do Chu tch hoac Pho Chu tch Uy ban
nhan dan tnh lam Trng Ban, lanh ao S Nong nghiep va Phat trien nong thon lam Pho Trng ban;
- Phe duyet va ch ao to chc thc hien Chng trnh khong che va thanh toan benh LMLM
cua tnh, ke hoach hang nam va kiem tra viec thc hien cua cac cap, nganh thuoc tnh;
- Chu tch Uy ban nhan dan tnh cong bo dch, cong bo het dch LMLM tren a ban cua tnh;
- Cap kinh ph cho cong tac phong chong dch t quy phong chong thien tai va ngan sach a phng.
b) S Nong nghiep va Phat trien nong thon
- Tham mu cho Uy ban nhan dan tnh trong viec xay dng chng trnh khong che va thanh
toan benh LMLM cua tnh va ke hoach hang nam tren c s Chng trnh quoc gia;
- To chc thc hien va kiem tra cong tac phong chong benh cua tnh.
c) Chi cuc Thu y
- Trc tiep ch ao to chc trien khai va kiem tra cong tac phong chong benh LMLM tren a
ban tnh;
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- Hng dan chuyen mon ve cac bien phap phong chong benh LMLM.
2. Cap huyen
a) Uy ban nhan dan huyen
- Thanh lap Ban ch ao phong chong benh LMLM huyen do Chu tch hoac Pho chu tch Uy
ban nhan dan lam trng ban, Lanh ao Phong Nong nghiep va Phat trien nong thon, Phong Kinh
te (hoac Tram Thu y huyen) lam Pho Trng ban;
- Phoi hp vi Chi cuc Thu y tnh ch ao Tram Thu y huyen, cac Ban, nganh, to chc, ca nhan
co lien quan a phng thc hien cac bien phap phong chong benh LMLM tren a ban huyen.
- Huy ong lc lng phuc vu cong tac phong chong benh ac biet cong tac tiem phong, tieu
huy gia suc mac benh va van chuyen gia suc ra vao a ban;
- Cap ngan sach a phng cho cong tac phong chong dch cua huyen.
b) Phong Nong nghiep va Phat trien nong thon, Phong Kinh te, Tram Thu y
- Trc tiep to chc thc hien cong tac phong chong dch tai huyen;
- Hng dan ky thuat cac bien phap phong chong en tan xa, thon;
- Bao cao kp thi nhu cau ve kinh ph, vat t hoa chat, vac xin, lao ong, v.v... cho Uy ban nhan
dan huyen va Chi cuc Thu y tnh.
3. Cap xa
a) Uy ban nhan dan xa
- Thanh lap Ban ch ao phong chong benh LMLM xa do Chu tch Uy ban nhan dan lam Trng
ban vi s tham gia cua cap uy ang, chnh quyen, oan the va can bo thu y, nong nghiep;
- Bo tr to chuyen mon e hng dan ky thuat, thng trc va tong hp tnh hnh dch benh;
- Ch ao trng thon trc tiep kiem tra, giam sat tnh hnh dch benh; phoi hp vi cac to chc
oan the quan chung (oan Thanh nien, Hoi Phu n, Hoi Nong dan, Hoi Cu chien binh va cac
to chc oan the khac) van ong nhan dan giam sat va thc hien cac bien phap phong chong dch.
Moi thon to chc ky cam ket thc hien 5 khong;
- Thanh lap oi xung kch chong dch, gom dan quan t ve, thanh nien, can bo thu y, cong an,
e tieu huy gia suc b benh, ve sinh tieu oc kh trung, giam sat ngi ra vao o dch, trc gac tai
cac chot kiem dch ong vat.
b) Nhan vien thu y xa
- Giam sat phat hien benh LMLM en tan ho chan nuoi, c s chan nuoi tren a ban xa va bao
cao kp thi cho Uy ban nhan dan xa va Tram Thu y huyen;
- Trc tiep tham gia cong tac phong chong benh, trc tiep tiem phong vac xin;
- Trc tiep tham gia trong giam sat kinh ph ho tr phong chong benh LMLM en chu chan nuoi.
ieu 15. Trach nhiem cua chu vat nuoi
1. am bao ieu kien chan nuoi ve a iem, chuong trai, con giong, thc an, nc uong, ve
sinh, x ly chat thai theo quy nh cua phap luat ve thu y;
2. Khi nghi ng gia suc mac benh phai bao ngay cho nhan vien thu y hoac Trng thon;
3. Chap hanh nghiem chnh cac bien phap phong chong benh LMLM theo Quy nh nay.
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******** ********
QUYET NH
VE VIEC SA OI QUYET NH SO 38/2006/Q-BNN NGAY 16/5/2006 CUA BO TRNG BO
NONG NGHIEP VA PHAT TRIEN NONG THON VE VIEC BAN HANH QUY NH PHONG CHONG
BENH L MOM LONG MONG GIA SUC
Can c Phap lenh Thu y ngay 29 thang 4 nam 2004;

Can c Ngh nh so 33/2005/N-CP ngay 15 thang 3 nam 2005 cua Chnh phu quy nh chi tiet
thi hanh mot so ieu cua Phap lenh Thu y;
Can c Luat Ban hanh van ban quy pham phap luat ngay 12 thang 11 nam 1996; Luat sa oi, bo
sung mot so ieu cua Luat Ban hanh van ban quy pham phap luat ngay 16 thang 12 nam 2002;
Can c Ngh nh so 86/2003/N-CP ngay 18 thang 7 nam 2003 cua Chnh phu quy nh chc
nang, nhiem vu, quyen han va c cau to chc cua Bo Nong nghiep va Phat trien Nong thon;
Theo e ngh cua Cuc trng Cuc Thu y,
QUYET NH:
ieu 1: Sa oi ieu 9, iem b, c khoan 3, khoan 5 ieu 10 va ieu 11 cua quy nh ve phong
chong benh L mom long mong gia suc ban hanh kem theo Quyet nh so 38/2006/Q-BNN ngay
16/5/2006 cua Bo trng Bo Nong nghiep va Phat trien nong thon nh sau:
"ieu 9. Cong bo dch
1. Chu tch Uy ban nhan dan cap tnh ra quyet nh cong bo xa co dch khi dch xuat hien 1
thon tr len va co u ieu kien cong bo dch theo quy nh tai ieu 17 cua Phap lenh Thu y.
2. C quan thu y co tham quyen thong bao ket qua xet nghiem benh tai xa co dch.
ieu 10. X ly o dch
1. Cach ly va nuoi nhot gia suc mac benh
Chu nuoi gia suc khi phat hien gia suc nhiem benh phai nuoi cach ly va bao ngay cho trng
thon hoac nhan vien thu y.
2. Xac minh va chan oan
Khi nhan c thong bao, trong pham vi mot ngay can bo thu y huyen phai tien hanh xac minh
va lay mau chan oan benh.
3. Chu tch Uy ban nhan dan cap xa co trach nhiem
a) Ch ao trng thon va nhan vien thu y kiem tra, giam sat chu nuoi gia suc thc hien cach
ly gia suc mac benh vi gia suc khoe, nhot trau, bo, ln, de, cu tai chuong hoac ni co nh; giup
can bo thu y huyen lay mau benh pham; thong ke so lng, loai gia suc mac benh, so ho gia nh
co gia suc mac benh, tong an gia suc cam nhiem trong thon.
b) Lap chot kiem dch ong vat tam thi tren cac truc ng giao thong chnh ra vao xa co dch
va vung khong che vi s tham gia cua lc lng thu y, cong an, dan quan t ve trc 24/24 gi
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nham ngan chan khong a gia suc, san pham gia suc ra ngoai xa co dch. at bien bao khu vc
co dch, hng dan tranh i qua xa co dch. To chc phun kh trung cac phng tien van chuyen t
xa co dch i ra ngoai.
c) Thc hien tieu huy gia suc mac benh trong xa co dch
- oi tng tieu huy
+ Tieu huy bat buoc toan bo so ln, de, cu, hu, nai trong cung mot o chuong neu trong o chuong
o co con mac benh vi trieu chng lam sang ien hnh ma khong phai ch ket qua xet nghiem.
Trng hp con nghi ng phai nuoi cach ly ch ket qua xet nghiem, neu ket qua dng tnh th tieu
huy. Viec tieu huy gia suc benh phai thc hien theo hng dan va giam sat cua c quan thu y;
+ Tieu huy bat buoc trau bo mac benh trong cac trng hp sau:
* Trau, bo mac benh trong o dch xuat hien lan au tien tai thon;
* Trau, bo mac benh vi typ vi rut LMLM mi hoac typ vi rut a lau khong xuat hien tren a ban tnh.
+ oi vi trau, bo khong thuoc dien neu tren th khuyen khch tieu huy hoac co the nuoi gi
nhng phai quan ly chat che nh sau:
* anh dau va co so sach theo doi theo hng dan cua Cuc Thu y;
* Nuoi cach ly vi an gia suc cha mac benh va theo doi sc khoe thng xuyen, tang cng
che o cham soc, nuoi dng;
* c giet mo tieu thu tai xa theo hng dan cua thu y;
* c phep van chuyen ra khoi xa e tieu thu sau hai nam tnh t ngay con vat khoi trieu
chng lam sang.
- Cach tieu huy
+ ot: ao ho, cho gia suc vao ho va ot bang cui, than, xang, dau. Sau o lap at va nen chat;
+ Chon: ao ho co kch thc tuy theo so lng gia suc can tieu huy, cho gia suc mac benh
xuong ho, phun thuoc sat trung hoac o voi bot len be mat gia suc va lap at. Khoang cach t be
mat gia suc chon en mat ho chon toi thieu la 1 met, nen at tren be mat that chat;
+ a iem ot, chon c ghi vao so va tren ban o cua xa e lu gi.
) Ve sinh, tieu oc kh trung
- Tai o dch
+ Ve sinh c gii: Thu gom chat thai, phan rac ni nuoi nhot gia suc b benh e ot hoac chon;
ra nen chuong, dung cu chan nuoi bang nc xa phong. Cong viec nay do chu gia suc thc hien;
+ Ve sinh hoa chat: Sau khi ve sinh c gii, e kho va tien hanh phun hoa chat kh trung thch
hp vi tng oi tng. Cong viec nay do oi chong dch cua xa thc hien.
- Vung xung quanh o dch
+ Chu chan nuoi gia suc phai to chc ve sinh c gii chuong trai, dung cu chan nuoi, tranh tiep
xuc vi vung co dch;
+ oi chong dch cua xa to chc phun thuoc kh trung khu vc chan nuoi, chuong trai, rac voi
bot ng lang, ngo xom.
e) Tiem phong vac xin bao vay
- To chc tiem phong vac xin cho trau, bo, de, cu, ln nai, ln c giong vung khong che,
tiem t ngoai vao trong. Sau khi tiem c 14 ngay, tien hanh tiem cho ong vat cam nhiem vung
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dch nhng khong mac benh; khong tiem cho gia suc a khoi trieu chng lam sang (trong trng
hp khong tieu huy).
- Huy ong lc lng tiem phong va ho tr tiem phong; ngi trc tiep tham gia tiem phong phai
la nhan vien thu y hoac ngi a qua tap huan.
- Chi cuc Thu y tnh hng dan, quan ly va giam sat viec tiem phong.
4. Chu tch Uy ban nhan dan cap huyen c Uy ban nhan dan tnh uy quyen ra quyet nh tieu huy gia
suc mac benh da tren chnh sach ho tr cua Chnh phu sau khi co e ngh bang van ban cua Chi cuc Thu y.
5. Khong c buon ban gia suc, san pham gia suc cam nhiem vi benh; khong to chc trien
lam, tham quan, vui chi trong xa co dch.
6. Che o bao cao: trong thi gian co dch, Uy ban nhan dan cap di co trach nhiem bao cao
hang ngay len Uy ban nhan dan cap tren, c quan thu y cap di co trach nhiem bao cao hang ngay
len c quan thu y cap tren cho en khi co quyet nh cong bo het dch;
Ngay khi xay ra dch, Chi cuc Thu y phai thong bao ngay cho Chi cuc Thu y cac tnh, thanh pho
lan can biet e chu ong phong, chong benh.
Chu tch Uy ban nhan dan cap tnh ch ao chnh quyen a phng cac cap, cac nganh thc hien
cac nhiem vu cu the sau:
1. Xac nh thon, xa, huyen co dch e khoanh vung o dch va lap cac chot kiem dch tam thi
co ngi trc 24/24 gi, co bien bao, hng dan giao thong; ngan cam viec a gia suc va san
pham cua chung ra ngoai xa co dch. Tai cac chot nay phai co phng tien va chat sat trung e
x ly moi oi tng ra khoi xa co dch;
2. Khong c van chuyen gia suc cam nhiem vi benh LMLM va san pham cua chung ra khoi xa co dch.
3. Gia suc khong mac benh, san pham gia suc c lay t gia suc khong mac benh LMLM c
phep van chuyen trong cac trng hp sau:
a) Gia suc, san pham gia suc tai cac xa thuoc vung khong che c phep van chuyen e tieu
thu trong pham vi huyen.
b) Van chuyen e tieu thu trong pham vi tnh:
- Gia suc, san pham gia suc tai vung em;
- Gia suc, san pham gia suc cua c s chan nuoi c cong nhan an toan dch benh LMLM tai
vung khong che.
c) Van chuyen ra khoi tnh e tieu thu:
- Gia suc, san pham gia suc ngoai vung em;
- Gia suc, san pham gia suc cua c s chan nuoi c cong nhan an toan dch benh LMLM tai vung em".
ieu 2. Quyet nh nay co hieu lc thi hanh sau 15 ngay, ke t ngay ang Cong bao.
ieu 3. Cuc trng Cuc Thu y, Thu trng cac n v co lien quan va Giam oc S Nong nghiep va
phat trien nong thon cac tnh, thanh pho trc thuoc Trung ng chu trach nhiem thi hanh Quyet nh nay./.
BO TRNG
Cao c Phat
115
******** ********
So: 04/2011/TT-BNNPTNT Ha Noi, ngay 24 thang 01 nam 2011
THONG T
HNG DAN CAC BIEN PHAP PHONG, CHONG BENH DCH TA LN
Can c Ngh nh so 01/2008/N-CP ngay 03/01/2008 cua Chnh phu Quy nh chc nang,
nhiem vu, quyen han va c cau to chc cua Bo Nong nghiep va Phat trien nong thon. Ngh nh
so 75/2009/N-CP ngay 10/9/2009 cua Chnh phu ve viec sa oi ieu 3 Ngh nh so 01/2008/
N-CP ngay 03/01/2008;
Can c Ngh nh so 33 /2005/N-CP ngay 15/3/2005 cua Chnh phu Quy nh chi tiet thi hanh
Bo Nong nghiep va Phat trien nong thon quy nh ve phong, chong benh dch ta ln, cu the nh sau:
Chng I
NHNG QUY NH CHUNG
ieu 1. Pham vi ieu chnh
Thong t nay quy nh ve phong benh, chong benh dch ta ln va trach nhiem cua cac c quan,
chnh quyen a phng, to chc, ca nhan trong phong, chong benh dch ta ln.
ieu 2. oi tng ap dung
Thong t nay ap dung oi vi c quan, to chc, ca nhan trong va ngoai nc co hoat ong chan
nuoi ln; van chuyen, giet mo, buon ban ln va cac san pham co nguon goc t ln; ong vat khac
cam nhiem vi benh dch ta ln.
Trong Thong t nay, cac t ng di ay c hieu nh sau:
1. Ln mang trung: La trng hp ln mang mam benh, nhng khong co bieu hien trieu chng
lam sang cua benh.
2. Ca benh dch ta ln: La cac trng hp ln nhiem vi rut dch ta ln va phat thanh benh vi
cac trieu chng lam sang va benh tch mo kham boc lo ro, co the phat hien thay bang mat thng.
3. O dch ta ln: La s xuat hien cua mot hoac nhieu ca benh dch ta ln a ban mot trang
trai chan nuoi hoac mot thon, ap.
4. Vung co dch ta ln: La vung co nhieu o dch dch ta ln a c c quan thu y co tham quyen
xac nh.
ieu 4. Gii thieu chung ve benh dch ta ln
1. Khai nhiem benh: Benh dch ta ln (Classical Swine Fever) la benh truyen nhiem cua loai
ln, gay ra bi mot loai vi rut co cau truc ARN thuoc giong Pesti vi rut, ho Flaviridae. Benh ch xay ra
loai ln (ke ca ln nha va ln rng) vi cac the cap tnh, a cap tnh, man tnh hoac dang khong ien
hnh. Mc o tram trong cua benh tuy thuoc vao oc lc cua vi rut, tuoi cua ong vat man cam va thi
gian nhiem benh. Ln trng thanh thng b benh t tram trong hn va cung co nhieu c hoi phuc
116
hoi hn so vi ln con. Benh dch ta ln co toc o lay lan rat nhanh va ty le chet en 90% va thng
ghep vi benh khac nh benh Pho thng han, Tu huyet trung, ong dau ln, benh do Mycoplasma.
Benh dch ta ln c phat hien lan au tien nam 1810 Tennessce, o dch au tien c ghi
nhan tai bang Ohio My nam 1833, en nay a xuat hien nhieu nc tren the gii. Hien nay, benh
dch ta ln van la moi e doa nguy hiem cho nganh chan nuoi ln nhieu nc tren the gii.
nc ta, benh dch ta ln c phat hien vao cac nam 1923 1924, en nay van ton tai pho bien
mot so ni. T nhng nam 1980, vi viec tiem phong vac xin gay mien dch cho an ln a khong
che c cac t dch ln. Tuy nhien, cho en nay benh van ton tai va xay ra rai rac nhng ni co
ln khong c tiem phong hoac tiem phong khong ung ky thuat. Hien nay, benh van la moi e doa
ln oi vi nganh chan nuoi ln, gay kho khan cho viec chan nuoi hang hoa va xuat khau.
Benh dch ta ln nc ta xay ra quanh nam, tuy nhien do thi tiet thay oi (the hien ro mien
Bac) va do bien ong cua an ln trong nam nen benh co luc tang luc giam. Ngoai ra, benh dch ta
ln con phu thuoc rat nhieu vao ty le tiem phong, ln ln a co mien dch b giet mo, ln con thay
an bo sung vao cha kp tiem phong lam cho ty le ln man cam trong an tang len. Viec tiem
phong theo mua vu va tiem phong bo sung thng xuyen gop phan on nh va han che dch benh
rat nhieu, nhng trong san xuat thc te do nhieu ly do nen viec tiem phong cha thc hien ung
quy nh, v vay dch ta ln van xay ra vao cac thang trong nam.
2. Tac nhan gay benh dch ta ln: do vi rut (Tortoi suis) thuoc ho Flaviridae, giong Pesti vi rut,
co quan he mat thiet vi vi rut gay benh tieu chay bo va vi rut gay benh Border cu. Cho en
nay ch co mot serotype cua vi rut DTL a c xac nh.
Vi rut DTL co sc e khang yeu, mac du co kha nang ton tai lau ngoai canh (trong phan gia
suc vi rut co the song sot trong vai ngay, song lau cac san pham tht, tht ln ong lanh va chnh
nhng san pham nay la nguon gieo rac benh nguy hiem ve mat dch te hoc), tuy nhien vi rut de b
tieu diet bi cac chat sat trung thong thng nh xut (NaOH) 2%, nuc voi 5%. nhiet o cao vi
rut b tieu diet nhanh.
Vi rut dch ta ln co the song vai thang en vai nam trong tht ong lanh. Thong qua con ng
thng mai, van chuyen, vi rut co trong cac san pham cua ln co the du nhap vao cac nc hoac cac
vung ang an toan dch. Ln man cam co the nhiem khi an phai thc an co cha vi rut nh cac thanh
phan phu pham cua qua trnh giet mo hoac thc an tha, chat thai t nha bep khong qua x ly.
3. Nguon benh va qua trnh truyen lay cua dch ta ln
a) Loai mac benh: Benh dch ta ln co moi la tuoi, loai ln, nhng mac manh nhat la ln con
2-3 thang tuoi, ln di 2 thang, khang the c truyen qua bao thai cua me, qua sa au. V vay,
thi ky nay t b nhiem benh hn. Trong phong th nghiem dung ln con lam ong vat th nghiem.
b) Chat cha Vi rut: Cac chat bai tiet, dch tiet, mau, hach lam ba, lach ln benh co cha vi rut.
Mau cua nhng con vat nung benh, sau 24 gi co kha nang gay benh. Nhng con khoi benh sau 2
thang van bai thai mam benh ra ngoai.
c) ng truyen lay: Vi rut xam nhap chu yeu qua ng tieu hoa, qua niem mac, qua vet
thng da va mot phan qua he thong ho hap. Thng lay trc tiep t con om sang con khoe, qua
thc an, nc uong, gian tiep qua cac chat bai tiet, dung cu chan nuoi, phng tien van chuyen hay
do cac ong vat khac mang mam benh truyen lay.
4. Trieu chng, benh tch cua benh dch ta ln
a) Trieu chng:
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Thi gian nung benh t 3-7 ngay va benh co the xuat hien mot trong 3 the:
The qua cap tnh (con goi la benh dch ta ln trang): Benh xuat hien ot ngot, khong co trieu
chng ban au (tien chng), con vat u ru, bo an, sot cao 41-420C, con vat giay giua roi chet nhanh
trong vong 24-48 gi. Dien bien trong vong 1-2 ngay, ty le chet ti 100%.
The cap tnh: Ln u ru, kem an, roi bo an, sot cao 41-420C keo dai en luc gan chet, mat viem
o co d, chay nc mui, mieng co loet phu nha vang li, chan rang, hau; ln thng b oi ma,
th kho, nhp th roi loan. Luc au tao bon sau o tieu chay phan bet vao mong, uoi mui thoi
kham co khi co mau ti. Tren da co nhieu iem xuat huyet lam tam tai, mom, bung va 4 chan.
Vao cuoi ky benh, ln b bai 2 chan sau i loang choang hoac khong i c. Neu ghep vi cac
benh khac th cac trieu chng tren tram trong hn.
The man tnh: Ln tieu chay gay yeu, ln benh chet do kiet sc, ln co the khoi benh nhng
van mang vi rut.
b) Benh tch:
Mo kham benh tch the cap tnh thay co s bai huyet, xuat huyet nang cac c quan noi tang,
amidan xuat huyet, co not loet ng tieu hoa, niem mac mieng, li tu mau, loet, da day b tu
huyet, xuat huyet thng nang ng cong ln, van hoi manh trang xuat huyet co nhng vet
loet hnh cuc ao, co vong tron ong tam b vet loet cao phu nha vang. Phoi b xuat huyet va tu
huyet. Tim b xuat huyet m vanh tim, ngoai tam mac, gan b tu huyet xuat huyet, tui mat co
nhng iem xuat huyet. Lach co hien tng nhoi huyet ra lam cho lach co hnh rang ca, than
co nhieu iem xuat huyet lam tam nh au ghim vo than va tuy than, be than mau hoac co cuc
mau, niem mac bang quang b tu huyet, xuat huyet.
Trong trng hp benh man tnh thng thay ruot co nhng vet loet lom sau, b cao phu nha
vang, phoi co the b viem dnh vao long ngc.
Tuy nhien, thc te nc ta cho thay benh thng ghep vi mot so benh khac nen trieu chng
va benh tch co thay oi tuy theo ghep vi benh nao. Mat khac, do a to chc tiem phong vac xin
nhieu nam, nen nhieu trng hp khong phat hien ay u cac benh tch ien hnh neu tren.
Chng II
PHONG BENH
ieu 5. Tuyen truyen phong, chong benh dch ta ln

1. Cuc Thu y xay dng noi dung va to chc thc hien chng trnh tuyen truyen phong, chong
benh dch ta ln. Hng dan Chi cuc Thu y tnh, thanh pho trc thuoc Trung ng (sau ay goi la
Chi cuc Thu y) trien khai chng trnh truyen thong a phng.
2. Uy ban nhan dan cac cap ch ao cac c quan chuyen mon, cac to chc oan the thc hien
thong tin tuyen truyen tai a phng theo noi dung tuyen truyen cua c quan thu y.
3. Cac c quan thong tin ai chung, c quan chuyen mon va cac to chc oan the thc hien
tuyen truyen pho bien kien thc ve benh dch ta ln, tnh chat nguy hiem cua benh va cac bien
phap phong chong ti ngi chan nuoi, ngi buon ban, giet mo, van chuyen, tieu thu trong tng
thon, xom, xa, phng va th tran. Cong tac thong tin tuyen truyen phai thc hien thng xuyen,
118
lien tuc, ay u e giup ngi chan nuoi hieu ung, ay u va chu ong thc hien cac bien phap
phong chong dch benh, bao gom:
a) Ap dung cac bien phap an toan sinh hoc trong chan nuoi;
b) Con giong am bao ro nguon goc, at tieu chuan chat lng; c tiem phong ay u vac xin
phong cac benh truyen nhiem nguy hiem theo quy nh;
c) Tuyen truyen e ngi dan cam ket thc hien 3 khong: khong dau khi ln mac benh, khong
ban chay ln benh, khong vt ln chet ba bai.
d) Tuyen truyen e ngi chan nuoi tng bc thay oi phng thc chan nuoi, chuyen t chan
nuoi nho le, phan tan sang chan nuoi theo hng quy mo trang trai tap trung, cong nghiep, ap dung
cac bien phap an toan sinh hoc.
ieu 6. Ap dung chan nuoi theo phng phap an toan sinh hoc
1. Ngi chan nuoi phai thc hien cac bien phap chan nuoi an toan sinh hoc nh sau:
a) Ve sinh, tieu oc kh trung chuong trai, dung cu chan nuoi thng xuyen: mua he hang ngay
co ra chuong, mang an, mang uong.
b) Sau khi xuat ban ln, phai tong tay ue, phun kh trung tieu oc chuong trai, moi trng va
e trong chuong t 5-7 ngay.
c) Ln mi mua ve phai nhot rieng t nhat 7 ngay e theo doi lam sang cho en khi chac chan
ln khong co benh mi c nhap nuoi chung vi an ln cu ang co.
d) Cham soc nuoi dng tot, han che khach tham quan.
2. Uy ban nhan dan cac cap co trach nhiem ch ao cac ban, nganh hu quan, to chc, ca nhan
chan nuoi ln tai a phng thc hien theo Quyet nh so 66/2008/Q-BNN ngay 04/6/2008 cua
Bo Nong nghiep va Phat trien nong thon ve xay dng vung, c s an toan dch benh.
ieu 7. Phong benh bang vac xin
1. Chu vat nuoi phai thc hien viec tiem phong bat buoc theo Quyet nh so 63/2005/Q-BNN
ngay 13/10/2005 cua Bo trng Bo Nong nghiep va Phat trien nong thon quy nh ve tiem phong
bat buoc vac xin cho gia suc, gia cam.
2. Tiem phong benh dch ta ln phai c thc hien nh ky moi nam 2 lan vao thang 3-4 va
thang 9-10. Tiem phong bo sung oi vi ln mi sinh, ln cha c tiem trong thi gian tiem
nh ky, tiem nhac lai oi vi ln het thi gian mien dch. Viec s dung vac xin phai theo hng
dan cua nha san xuat.
3. Tiem phong benh dch ta ln phai thc hien nh sau:
a) oi vi ln con sinh ra t ln me a c tiem phong: tiem cho ln con t 35 - 45 ngay tuoi;
b) oi vi ln con sinh ra t ln me cha c tiem phong: Co the tiem cho ln con 7 ngay tuoi,
sau 3 tuan sau tiem nhac lai hoac tiem cho ln con 14 ngay tuoi, sau 2 tuan sau tiem nhac lai.
c) oi vi ln nai mang thai: tiem phong trong thi gian mang thai t 30 - 85 ngay mang thai;
4. Cac c s chan nuoi ln giong, c s chan nuoi ln quy mo tap trung (so lng ln nuoi t
200 con tr len) phai thc hien giam sat huyet thanh sau tiem phong e bao am an ln c tiem
phong co mien dch bao ho.
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ieu 8. Thc hien chu ong giam sat, phat hien benh
1. To chc, ca nhan chan nuoi ln phai thc hien giam sat lam sang oi vi an ln e chu ong
phat hien benh kp thi: quan sat, phat hien nhng trieu chng lam sang, benh tch ien hnh cua
ln benh, ln chet, nhng ac iem ve dch te hoc.
2. C s chan nuoi ln giong phai thc hien giam sat s lu hanh cua vi rut dch ta ln, nh sau:
a) nh ky kiem tra huyet thanh e xac nh trang thai mang trung ln nai va ln c giong.
b) Khi phat hien ln nai va ln c giong mang trung, phai thc hien giet mo bat buoc di s
giam sat chat che cua C quan Thu y.
ieu 9. Kiem dch va kiem soat van chuyen
1. Chi cuc Thu y thc hien kiem dch ln tai ni xuat phat va cap giay chng nhan kiem dch theo quy
nh oi vi an ln khoe manh, a c tiem phong vac xin dch ta ln va con thi gian mien dch bao ho.
2. Cac tram, chot kiem dch ong vat tai cac au moi giao thong co nhiem vu kiem soat, phat
hien van chuyen ln mac benh, ln t vung co dch va x ly cac trng hp vi pham nh sau:
a) Tieu huy ln mac benh.
b) Buoc cach ly ln co nguon goc t vung co dch trong trng hp khong co giay chng nhan
kiem dch e theo doi. Neu ln sot, co trieu chng cua benh dch ta ln th thc hien tieu huy.
c) Buoc chu hang thc hien kiem dch oi vi ln khoe manh, khong co bieu hien lam sang cua
benh nhng khong co giay chng nhan kiem dch.
d) oi vi ln co giay chng nhan kiem dch ni xuat phat nhng khong hp le th tam gi e
chu hang bo sung ho s.
) X phat nghiem cac trng hp vi pham theo quy nh cua phap luat.
3. Khi cac tnh lien ke co dch, Chu tch Uy ban nhan dan tnh, thanh pho trc thuoc Trung ng
(sau ay goi la Uy ban nhan dan cap tnh) quyet nh thanh lap tram, chot kiem dch tam thi tai
au moi giao thong theo e ngh cua S Nong nghiep va Phat trien nong thon e kiem soat viec
van chuyen ln.
4. Van chuyen qua bien gii:
a) Chu tch Uy ban nhan dan cac tnh bien gii ch ao cac cap, cac nganh tang cng cong tac
kiem tra, kiem soat, ngan chan, x ly ln nhap lau;
b) Tram kiem dch bien gii thng xuyen thc hien kh trung, tieu oc moi phng tien van
chuyen qua ca khau.
5. Chi cuc Thu y phai kiem soat ln nhap vao tnh va x ly nghiem theo quy nh oi vi cac
trng hp vi pham, cu the: ln nhap vao tnh khong co giay kiem dch; cha tiem phong vac xin
dch ta ln; ln khong ro nguon goc.
6. To chc, ca nhan vi pham cac quy nh ve kiem dch van chuyen b x phat vi pham hanh
chnh va phai chu moi chi ph cho viec kiem dch, x ly tieu huy ln.
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Chng III
CHONG DCH
ieu 10. Khai bao va x ly oi vi o dch au tien
1. Chu vat nuoi khi phat hien ln co trieu chng lam sang cua benh dch ta ln nh: sot cao, bo
an hoac an t, mat co ghen, vung da mong xuat huyet lam cham nh muoi ot th phai khai bao
ngay vi c quan thu y ni gan nhat hoac nhan vien thu y xa hoac trng thon, ap; ong thi cach
ly ngay ln mac benh ra khu vc khac.
2. Khi nhan c thong bao nghi co ln mac benh dch ta ln, can bo thu y c s phai bao cao
ngay vi Tram Thu y huyen bang ien thoai, sau o phai bao cao bang van ban ghi ro ten, a ch
chu vat nuoi va cac noi dung khac co lien quan gi cho Uy ban nhan dan xa, phng, th tran va c
quan thu y cap tren trc tiep.
3. Tram Thu y huyen: trong vong 24 gi sau khi nhan c thong bao cua can bo thu y c s
hoac chu vat nuoi, phai c can bo en kiem tra, xac minh va hng dan chu vat nuoi cac bien phap
cach ly ln mac benh, ve sinh, kh trung tieu oc.
4. Tram Thu y huyen lay mau benh pham gi xet nghiem oi vi nhng con vat au tien mac
benh trong pham vi huyen, ong thi bao ngay cho c quan thu y cap tren. Ky thuat lay mau, bao
quan mau benh pham phai tuan thu nghiem ngat hng dan cua Cuc Thu y.
5. Trong trng hp can thiet, Chi cuc Thu y e xuat vi Uy ban nhan dan cap tnh hoac Uy ban
nhan dan cap huyen c uy quyen ra quyet nh tieu huy ln trong o dch ma khong can ch ket
qua xet nghiem.
ieu 11. Chan oan, xet nghiem benh dch ta ln:
1. Lay mau chan oan: Yeu cau lay benh pham thch hp, gi phong th nghiem e chan oan.
Viec chan oan phai c thc hien nhanh chong, kp thi e giup phong, chong benh co hieu qua.
Phng phap lay mau benh pham c quy nh nh sau:
a) oi vi ln chet: Lay mau to chc la cac hach lam ba, than, phoi, lach, amidan, lach... Kch
thc mau to chc la: 1 1 0.5 cm.
b) oi vi ln om:
Trng hp benh cha c 8 ngay: Lay mau co chat chong ong (heparine, EDTA) khi con vat
sot cao 410C-420C e xet nghiem vi rut.
Trng hp benh a c tren 8 ngay (ln cha tiem phong vac xin dch ta ln): Mau ng
trong ong nghiem kho hoac xiranh chat huyet thanh e xet nghiem khang the khang dch ta ln.
2. Bao quan va gi mau benh pham: Mau can c gi en phong th nghiem cang nhanh, cang
tot, cham nhat la 03 ngay ke t luc lay mau; mau c ng trong lo (dung cu cha mau), bao goi, ghi
chep thong tin mau, bao quan nhiet o 40C. Gi mau kem theo phieu gi mau ghi ay u thong tin.
3. Xet nghiem, chan oan:
a) Chan oan da theo quy luat dch, tnh chat dch te, trieu chng, benh tch, chan oan bang
tr lieu, chan oan phan biet vi mot so benh thng gap va co kha nang nham lan vi dch ta ln
nh: ong dau ln, Tu huyet trung, Pho thng han, Cum ln, Nhiet than ln, au ln, Cam
nang, Trung oc, Suyen
b) e xac nh benh can can c vao ket qua xet nghiem mau benh pham trong phong th
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nghiem. Mot so phng phap chan oan trong phong th nghiem nh: soi knh hien vi ien t, tiem
ong vat th nghiem, phan ng trung hoa tren tho, chan oan bang khang the huynh quang, phan
ng ket tua khuyech tan tren thach, phan ng ngng ket gian tiep hong cau, ELISA, rRT-PCR.
ieu 12. Cong bo dch
1. Khi co u ieu kien cong bo dch theo quy nh tai ieu 17 cua Phap lenh Thu y th Chu tch
Uy ban nhan dan cap tnh ra quyet nh cong bo dch ong thi cong bo vung b uy hiep, vung em
va ap dung cac bien phap phong benh theo quy nh cua phap luat.
2. Pham vi cong bo dch c quy nh nh sau:
a) Dch xuat hien tren a ban xa th cong bo xa co dch;
b) Dch xuat hien 1/2 so xa tr len th cong bo dch toan huyen;
c) Dch xuat hien 1/2 so huyen tr len th cong bo dch toan tnh.
ieu 13. Cac bien phap chong dch
1. oi vi cac a phng lan au tien co dch ta ln xuat hien:
a) Khoanh vung dch: xa co dch c xac nh la vung dch; cac xa tiep giap vi xa co dch
c xac nh la vung b dch uy hiep;.
b) Chu tch UBND huyen huy ong cac lc lng thu y, cong an, quan ly th trng va cac c
quan, to chc khac co lien quan lap cac tram kiem dch, chot kiem dch cac truc giao thong chnh
xung quanh vung co dch va vung b dch uy hiep theo uy quyen cua Chu tch Uy ban nhan dan tnh;
c) Chu tch UBND cap xa huy ong cac lc lng thu y, cong an, thanh nien xung kch, cac to
chc oan the cua a phng tham gia chong dch. Cac bien phap chong dch can tap trung vao
nhng noi dung sau:
Giet mo bat buoc oi vi ln nghi mac benh dch ta ln, bang cach luoc chn than tht va tieu
huy phu tang.
Cam van chuyen ln mac benh, san pham cha qua che bien co nguon goc t ln, phan rac thai
chan nuoi ra khoi vung dch, vung b dch uy hiep trong thi gian co dch.
at bien bao ni co dch ta ln va han che ngi khong lien quan ra, vao vung dch; tieu oc,
kh trung moi phng tien ra khoi vung co dch.
Tien hanh kiem tra toan bo cac c s chan nuoi trong vung dch, vung b dch uy hiep nham phat
hien cac trng hp ln b benh; trong vong 1-3 ngay tai pham vi xa co dch va cac xa lien ke xung
quanh can lap danh sach thong ke cac ho, c s chan nuoi ln va cac ho co ln b benh e giam sat.
Khan trng tiem phong vac xin dch ta ln cho toan bo an ln trong vung dch.
2. oi vi cac a phng a tng co dch ta ln lu hanh, a phng co dch ta ln lay lan ra
dien rong:
a) oi vi nhng an ln chan nuoi nho le, khong ap dung ay u cac bien phap an toan sinh
hoc th tien hanh giet mo toan an va x ly che bien chn e tieu thu tai cho co s giam sat chat
che cua c quan thu y a phng. Sau khi giet mo can phai thc hien viec ve sinh, tong tay ue tieu
oc kh trung ni co ln mac benh, ni giet mo.
b) oi vi nhng c s chan nuoi co quy mo tap trung, theo hnh thc cong nghiep, ban cong
nghiep, cac trang trai ln co ap dung c cac bien phap an toan sinh hoc, th x ly nh sau:
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Tieu huy ngay toan bo so ln mi mac benh, ln mi chet v benh, ln benh co trieu chng ien
hnh cua benh dch ta ln; giet mo bat buoc oi vi nhng ln nuoi cung o chuong vi ln benh.
Giet mo tai cho nhng ln b benh nhe (sot nhe, co cac bieu hien lam sang ve ho hap) hoac ln
con khoe manh, x ly che bien trc khi tieu thu nham tranh phat tan mam benh. Trng hp giet
mo nhieu ln tai mot thi iem, c quan thu y a phng t van vi chnh quyen c s ch nh a
iem giet mo am bao ve sinh an toan thc pham, de tieu oc kh trung, tranh lam phat tan mam
benh, ong thi c can bo thu y giam sat viec giet mo.
oi vi cac trng hp mang trung, x ly giet mo bat buoc co giam sat cua c quan thu y; khong
tiep tuc khai thac oi vi ln nai, ln c mang trung, ong thi thc hien tieu oc, ve sinh kh
trung triet e toan bo khu vc co ln benh va cac khu vc xung quanh.
oi vi nhng ln khoe manh trong cung an ma khong giet mo th phai c nuoi cach ly
triet e; cham soc, bo sung dinh dng va khoang chat, cac loai vitamin nham tang cng sc
e khang phong benh.
Tong ve sinh, tieu oc kh trung vung dch, ni co ln om, ni giet mo e tranh lam phat tan
lay lan mam benh.
Khoanh vung, lap cac chot kiem dch, kiem tra viec van chuyen buon ban ln, san pham cua ln
t vung co dch ra ngoai vung cha co dch.
c) oi vi cac c s chan nuoi tap trung khong co ln mac benh nhng nam trong vung dch
(thon, ap co dch), ma am bao ve sinh an toan sinh hoc hoac a tiem vac xin phong dch ta ln con
mien dch th c phep van chuyen ra khoi vung dch, en thang lo giet mo c ch nh trc.
Ln phai c van chuyen bang xe chuyen dung, am bao khong lam ri vai chat thai (phan, nc
tieu) tren ng i; khong c dng ngh tren ng van chuyen. Phng tien van chuyen phai
c ve sinh, kh trung tieu oc ky trc khi ri khoi lo mo.
d) oi vi cac c s chan nuoi ln giong bat c quy mo nao: neu phat hien co ln benh trong
c s phai to chc tieu huy ln mac benh nang, giet mo bat buoc oi vi nhng con benh nhe.
Ln cha b benh phai c cham soc nuoi dng tot e chuyen sang muc ch nuoi thng pham.
Khong khai thac va s dung tinh dch cua ln c giong a b nhiem benh.
) Tiem bao vay xung quanh o dch, sau o tiem thang vac xin vao o dch vi muc ch nham
nhanh chong bao vay va dap tat o dch, con om phat benh, con khoe co mien dch.
3. X ly oi vi cac an co ln mac benh, chet:
a) Khi dch con dien hep: Tien hanh tieu huy ngay so ln mi mac benh tren c s trieu chng
benh tch ma khong ch ket qua xet nghiem.
b) Trng hp dch xay ra dien rong: nhieu ho gia nh co ln benh va nhieu ln mac benh th
tieu huy nhng ln b mac benh nang, nhng ln mac benh nhe x ly nh sau:
Ln co trong lng < 20kg phai tieu huy bang cach chon hoac ot.
Ln co trong lng > 20kg phai giet mo bat buoc va tht co the s dung lam thc pham sau khi
luoc chn. Phu tang va cac san pham khac phai tieu huy.
c) Tien hanh ve sinh tieu oc kh trung chuong trai, khu vc chan nuoi, loi ra vao, khu vc tap
trung ln phai tieu huy, khu vc tieu huy hoac chon lap ln. Nhng ngi tham gia qua trnh x ly,
tieu huy ln phai thc hien viec ve sinh, tam ra e tieu diet mam benh, tranh lam phat tan mam
benh ra cac a iem khac.
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d) Viec tieu huy, chon lap ln benh can thc hien nh sau:
Lam chet ln trc khi tieu huy bang ien hoac phng phap khac (neu co), cho ln vao bao tai,
buoc chat mieng bao, tap trung mot cho e phun thuoc sat trung trc khi van chuyen en ho chon.
Ho chon phai nam ngay trong vung dch, nhng phai cach nha dan, gieng nc, khu chuong nuoi
t 30-100m, co u dien tch; nen chon ni chon trong vn cay (cay an qua hoac lay go). Ho chon
phai u rong phu hp vi so ln, chat thai can chon. V du neu can chon 01 tan ln (15-30 con ln)
th ho chon can co kch thc la sau 1,5 - 2m x rong 1,5 - 2m x dai 1,5 - 2m.
Trnh t chon: Sau khi ao ho, rai mot lp voi bot xuong ay ho (1kg/m2), o bao cha xac ln
xuong ho, phun thuoc sat trung hoac rac voi bot len tren va lap at; phai am bao rang lp at phu
len xac ln phai day t nhat la 1m. Phun sat trung khu vc chon lap e hoan tat qua trnh tieu huy.
4. Bien phap x ly oi vi cac an cha co benh, vung cha co dch
a) oi vi nhng an ln chan nuoi nho le:
Khuyen khch viec giet mo, tieu thu tai cho oi vi nhng an nay.
Ap dung cac bien phap chan nuoi an toan sinh hoc va thng xuyen ve sinh tieu oc moi trng,
khu vc chan nuoi.
b) oi vi nhng c s chan nuoi ln tht quy mo tap trung:
Ap dung nghiem ngat cac bien phap chan nuoi an toan sinh hoc va thng xuyen ve sinh tieu
oc moi trng, khu vc chan nuoi.
Tang cng cham soc, nuoi dng, nang cao sc e khang cho ln.
Nhng c s am bao ieu kien ve sinh thu y, co ap dung cac bien phap an toan sinh hoc, a
tiem vac xin phong benh dch ta ln va con mien dch th c phep van chuyen ra khoi vung dch,
en thang lo giet mo c ch nh trc e giet mo. Ln phai c van chuyen bang xe chuyen
dung, am bao khong lam ri vai chat thai (phan, nc tieu) tren ng i; khong c dng ngh
tren ng van chuyen. Phng tien van chuyen phai c ve sinh, kh trung tieu oc ky trc khi
ri khoi c s chan nuoi va t lo giet mo.
c) oi vi cac c s chan nuoi ln nai, ln c giong: Trong bat ky trng hp nao, khong c
phep van chuyen ln giong ra khoi c s chan nuoi, vung ang co benh dch ta ln lu hanh va
ang gay thanh dch. Can thc hien theo doi, giam sat chat che an ln cho en khi co quyet nh
cong bo het dch tren a ban mi c phep van chuyen i a phng khac; tang cng cham soc,
nuoi dng cho an ln.
ieu 14. Cong bo het dch va chan nuoi tr lai cac c s a co dch xay ra
1. Chu tch Uy ban nhan dan cap tnh ra quyet nh cong bo het dch khi co u cac ieu kien sau ay:
a) Tat ca ln trong dien phai tiem phong thuoc vung dch, vung b dch uy hiep a c tiem vac
xin phong benh dch ta ln va a co mien dch;
b) a qua 21 ngay ke t ngay con ln cuoi cung b chet, b giet mo bat buoc hoac b tieu huy,
khong co con ln nao khac b mac benh hoac b chet v benh dch ta ln;
c) a thc hien ve sinh, kh trung tieu oc 2 lan/tuan lien tuc trong 2 tuan oi vi ho chan nuoi,
c s chan nuoi a b dch, vung co dch.
d) Chi cuc Thu y kiem tra xac nhan a u ieu kien cong bo het dch theo quy nh tai cac iem
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a, b, c khoan 1 ieu nay va co van ban e ngh cong bo het dch.
2. ieu kien chan nuoi tr lai:
a) a thc hien ve sinh, kh trung, tieu oc.
b) e trong chuong trong thi gian toi thieu la 21 ngay. Trc khi nuoi tr lai, c s chan nuoi
phai c ve sinh, phun thuoc tieu oc kh trung trc khi nuoi.
c) Ln a vao nuoi tr lai phai biet ro nguon goc, a c tiem vac xin phong cac benh truyen
nhiem cua ln theo quy nh.
d) Sau khi nuoi tr lai, can phai giam sat chat che, lien tuc trong vong 40 ngay (theo quy trnh
giam sat cua OIE) e e phong mam benh tai xuat hien va gay benh tr lai.
Chng IV
TO CHC THC HIEN
ieu 15. Trach nhiem cua c quan nha nc Trung ng
1. Trach nhiem cua Cuc Thu y
a) Xay dng Chng trnh quoc gia ve phong, chong benh dch ta ln, e Bo Nong nghiep va
Phat trien nong thon trnh Thu tng Chnh phu phe duyet; to chc, hng dan, on oc, kiem tra
viec thc hien Chng trnh cac a phng.
b) To chc, hng dan, kiem tra viec thc hien ke hoach giam sat benh dch ta ln cac a phng;
c) To chc thanh tra, kiem tra tren pham vi toan quoc ve cong tac phong, chong benh dch ta ln.
ieu 16. Trach nhiem cua c quan nha nc, to chc, ca nhan a phng
1. Trach nhiem cua Uy ban nhan dan tnh cap tnh
a) Ch ao nganh thu y, cac cap, cac nganh co lien quan xay dng Chng trnh phong, chong
benh va xay dng vung, c s an toan benh dch ta ln tai a phng;
b) Cung co, tang cng cho he thong thu y cap tnh, cap huyen, ac biet la mang li thu y xa,
phng co u ve so lng va am bao chat lng, c trang b ay u phng tien, trang thiet b
e thc thi nhiem vu. Cac a phng cha co mang li thu y xa, phng th thc hien Cong van
so 1569/TTg - NN ngay 19/11/2007 cua Thu tng Chnh phu ve viec thc hien che o phu cap cho
thu y xa, phng, Thong t lien Bo so 61/2008/TTLT-BNN-BNV ngay 15/5/2008 lien tch gia Bo
Nong nghiep va Phat trien nong thon va Bo Noi vu hng dan chc nang, nhiem vu, quyen han va
c cau to chc cua c quan chuyen mon thuoc Uy ban nhan dan cap tnh, cap huyen va nhiem vu
quan ly nha nc cua Uy ban nhan dan cap xa ve nong nghiep va phat trien nong thon;
c) Ch ao cac s, nganh, c quan chuyen mon va cac to chc oan the tai a phng thng
xuyen trien khai cong tac thong tin tuyen truyen phong chong benh dch ta ln;
d) Chu tch Uy ban nhan dan tnh cong bo dch, cong bo het dch ta ln tren a ban cua tnh
theo quy nh; quyet nh tieu huy ln mac benh dch ta ln hoac uy quyen cho Uy ban nhan dan
cap huyen ra quyet nh tieu huy.
2. Trach nhiem cua S Nong nghiep va Phat trien nong thon
a) Tham mu cho Uy ban nhan dan tnh trong viec xay dng chng trnh phong, chong benh
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dch ta ln cua tnh va ke hoach hang nam tren c s Chng trnh phong, chong benh dch ta
ln cap quoc gia;
b) Ch ao Chi cuc Thu y xac nh vung dch, vung b dch uy hiep, vung co nguy c cao vi
benh dch ta ln;
c) To chc thc hien va kiem tra cong tac phong chong benh dch ta ln cua tnh.
3. Trach nhiem cua Chi cuc Thu y
a) Trc tiep ch ao, to chc trien khai va kiem tra cong tac phong, chong benh dch ta ln tren
a ban tnh, thanh pho;
b) Hng dan chuyen mon ve cac bien phap phong chong benh, to chc trien khai giam sat dch
benh dch ta ln, thc hien che o bao cao ot xuat khi co dch xay ra, bao cao ve cong tac phong,
chong benh dch ta ln ve Cuc Thu y mot nam 2 lan vao 30/6 va 30/12 hang nam ve cac noi dung tong
an ln, ket qua tiem phong, tnh hnh benh dch ta ln (neu co), cong tac giam sat benh dch ta ln;
c) Tham mu, e xuat vi Uy ban nhan dan cap tnh, chu ong phoi hp vi C quan Thu y
vung, Trung tam Chan oan Thu y Trung ng thuoc Cuc Thu y xay dng chng trnh giam sat
dch oi vi an ln giong, ac biet tai cac vung chan nuoi tap trung, quy mo ln hoac cac gia trai,
trang trai chan nuoi tap trung, khu vc co nguy c cao, co o dch cu;
d) Tham mu cho S Nong nghiep va Phat trien nong thon lap d tru kinh ph quan ly giam sat
cong tac phong, chong dch benh ta ln tai a phng, trnh Uy ban nhan dan tnh phe duyet.
4. Trach nhiem cua Uy ban nhan dan cap huyen
a) Thanh lap Ban ch ao phong chong dch benh cap huyen. Trng Ban do Chu tch hoac
Pho chu tch Uy ban nhan dan. Pho trng ban do lanh ao Phong Nong nghiep hoac Phong Kinh
te, Tram Thu y huyen;
b) Thanh lap oi chuyen trach phong chong benh dch ta ln (kinh ph lay t ngan sach phong,
chong dch cua a phng);
c) Phoi hp vi Chi cuc Thu y ch ao cac Tram Thu y huyen, c quan, to chc, ca nhan co lien
quan thc hien cac bien phap phong, chong benh dch ta ln tren a ban huyen;
d) Huy ong lc lng phuc vu cong tac phong chong benh, ac biet cong tac tiem phong, tieu
huy, x ly ln mac benh;
) Cap ngan sach a phng cho cong tac phong chong dch cua huyen.
5. Trach nhiem cua Phong Nong nghiep hoac Phong Kinh te, Tram Thu y
a) Trc tiep to chc thc hien cong tac phong chong benh dch ta ln tai huyen;
b) Hng dan ky thuat cac bien phap phong chong en tan xa, thon;
c) Bao cao kp thi nhu cau ve kinh ph, vat t hoa chat, vac xin, lao ong, cho Uy ban nhan dan
huyen va Chi cuc Thu y.
d) Hang thang bao cao cong tac phong, chong benh dch ta ln ve Chi Cuc Thu y vi cac noi
dung: so ln, ket qua tiem phong, tnh hnh benh dch ta ln (neu co) cua cac huyen.
6. Trach nhiem cua Uy ban nhan dan cap xa
a) Thanh lap Ban ch ao phong chong dch benh cap xa do Chu tch Uy ban nhan dan lam
Trng ban vi s tham gia cua cap uy ang, chnh quyen, oan the va can bo thu y;
b) Bo tr to chuyen mon e hng dan ky thuat, thng trc va tong hp tnh hnh dch benh,
ket qua tiem phong;
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c) Ch ao trng thon trc tiep kiem tra, giam sat tnh hnh dch benh; phoi hp vi cac to chc
oan the quan chung (oan Thanh nien, Hoi Phu n, Hoi Nong dan, Hoi Cu chien binh va cac
to chc oan the khac) van ong nhan dan giam sat va thc hien cac bien phap phong chong dch.
Moi thon to chc ky cam ket thc hien 3 khong;
Thanh lap oi xung kch chong dch, gom: dan quan t ve, thanh nien, can bo thu y, cong an
e tieu huy, x ly ln b benh, ve sinh tieu oc kh trung, giam sat ngi ra vao o dch, trc gac tai
b) Nhan vien thu y xa: Giam sat phat hien benh dch ta ln en tan ho chan nuoi, c s chan
nuoi tren a ban xa va bao cao kp thi cho Uy ban nhan dan xa va Tram Thu y huyen;
Trc tiep tham gia cong tac phong chong benh, trc tiep tiem phong vac xin;
Trc tiep tham gia trong giam sat kinh ph ho tr phong chong benh dch ta ln.
sinh, x ly chat thai theo quy nh cua phap luat ve thu y.
2. Khi nghi ng ln mac benh phai bao ngay cho nhan vien thu y hoac trng thon.
3. Chap hanh nghiem chnh cac bien phap phong chong benh dch ta ln theo thong t nay.
ieu 18. Hieu lc thi hanh
Thong t nay co hieu lc thi hanh sau 45 ngay ke t ngay ky;
Trong qua trnh thc hien, neu co vng mac hoac can bo sung, sa oi, e ngh bao cao ve Bo
Nong nghiep va Phat trien nong thon e nghien cu, giai quyet./.
Ni nhan: KT. BO TRNG

- Thu tng, cac Pho Thu tng (e b/c);
- Van phong TW ang; TH TRNG
- Van phong Chnh phu;
- Lanh ao Bo;
- Cac Bo, nganh lien quan;
- UBND cac tnh, TP;
- Cac n v thuoc Bo;
- S Nong nghiep va PTNT cac tnh, TP; Diep Knh Tan
- Chi cuc Thu y cac tnh, TP;
- Cong bao CP;
- Cong bao webside CP;
- Lu: VT, TH, Cuc Thu y.
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******** ********
So: 05/2011/TT-BNNPTNT Ha Noi, ngay 24 thang 01 nam 2011
THONG T
HNG DAN CAC BIEN PHAP PHONG, CHONG BENH NIU-CAT-XN GIA CAM
Can c Ngh nh so 01/2008/N-CP ngay 03/01/2008 cua Chnh phu Quy nh chc nang,
nhiem vu, quyen han va c cau to chc cua Bo Nong nghiep va Phat trien nong thon;
Ngh nh so 75/2009/N-CP ngay 10/9/2009 cua Chnh phu ve viec sa oi ieu 3 Ngh nh so
01/2008/N-CP ngay 03/01/2008 cua Chnh phu Quy nh chc nang, nhiem vu, quyen han va c
cau to chc cua Bo Nong nghiep va Phat trien nong thon;
Can c Ngh nh so 33 /2005/N-CP ngay 15/3/2005 cua Chnh phu Quy nh chi tiet thi hanh
Bo Nong nghiep va Phat trien nong thon hng dan cac bien phap phong, chong benh
Niu-cat-xn, nh sau:
Chng I
QUY NH CHUNG
ieu 1. Pham vi ieu chnh

Thong t nay hng dan cac bien phap phong, chong benh Niu-cat-xn va trach nhiem cua cac
c quan, chnh quyen a phng, to chc, ca nhan trong phong, chong benh Niu-cat-xn.
ieu 2. oi tng ap dung
Thong t nay ap dung oi vi c quan, to chc, ca nhan trong va ngoai nc co hoat ong chan
nuoi gia cam, van chuyen, giet mo, buon ban gia cam va cac san pham co nguon goc t gia cam.
Trong Thong t nay, cac t ng di ay c hieu nh sau:
1. Nhiem vi rut Niu-cat-xn: La trng hp gia cam mang mam benh, nhng cha co bieu hien
trieu chng lam sang cua benh.
2. Ca benh Niu-cat-xn: La cac trng hp gia cam nhiem vi rut Niu-cat-xn va phat thanh
benh vi cac trieu chng lam sang va benh tch mo kham boc lo ro, co the phat hien thay bang
mat thng.
3. O dch Niu-cat-xn: La s xuat hien cua mot hoac nhieu ca benh Niu-cat-xn a ban mot
trang trai chan nuoi hoac mot thon, ap.
4. Vung co dch Niu-cat-xn: la vung co nhieu o dch Niu - cat - xn a c c quan thu y co
tham quyen xac nh.
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ieu 4. Benh Niu-cat-xn
1. Benh Niu-cat-xn (Newcastle) la benh truyen nhiem nguy hiem loai cam (ga, cac loai
chim), moi la tuoi eu co the mac benh, benh thng ghep vi nhieu benh gia cam khac gay ra
ty le chet cao, gay thiet hai kinh te ln.
Benh Niu-cat-xn c phat hien au tien nam 1926 tai thanh pho Newcastle, vung ong Bac nc
Anh. Benh a xuat hien khap cac chau luc tren the gii. Tai Viet Nam, hang nam dch van xay ra nhieu
a phng gay ton that ln cho nganh chan nuoi gia cam cua nc ta.
2. Tac nhan gay benh: Benh Niu-cat-xn do mot loai vi rut thuoc giong Avulavirus, ho Paramyxo-
viridae gay ra. Vi rut gay benh Niu-cat-xn co cau truc gen ARN xoan n. He gen cua vi rut cha
khoang 16.000 nu-cle-o-tt. Vi rut c nhan len trong te bao chat cua vat chu.
Da vao cac bieu hien ve trieu chng lam sang, co the phan loai benh Niu-cat-xn thanh 4
the benh chnh, bao gom: the oc lc cao hng noi tang (Viscerotropic velogenic), the oc lc cao
hng than kinh (Neurotropic velogenic), the oc lc trung bnh (Mesogenic) va the oc lc thap (Lento-
genic). Vi rut gay benh Niu-cat-xn oc lc cao co the gay chet gia cam trong thi gian ngan khi gia cam
cha xuat hien trieu chng lam sang. an gia cam cha c phong benh bang vac xin th khi nhiem
benh co the chet en 100%.
3. Cach lay truyen: Lay truyen trc tiep: Vi rut Niu-cat-xn thng lay truyen qua ng tiep
xuc trc tiep gia gia cam mac benh va gia cam khoe manh. Vi rut c bai thai qua phan, dch
tiet mat, mui, mieng hoac qua hi th cua gia cam benh.
Lay truyen gian tiep: Vi rut co the lay truyen thong qua xac gia cam b benh chet, vo trng,
dung cu chan nuoi, thc an nc uong, chat thai chan nuoi, ung hoac quan ao cua ngi chan nuoi
co mang mam benh.
4. Sc e khang: Vi rut Niu-cat-xn de b tieu diet nhiet o cao, nhiet o 700C trong 30 phut,
750C trong 5 phut va 800C trong vong 1 phut. Trong moi trng kiem hoac a-xt hoac di tac ong
trc tiep cua anh sang mat tri, vi rut de b pha huy. Trong ieu kien nhiet o thap, vi rut co the
ton tai trong thi gian dai ti nhieu tuan trong moi trng hu c nh phan, cac chat bai tiet hoac
tren long cua gia cam mac benh.
5. Trieu chng lam sang: Thi ky u benh: Thi ky u benh trung bnh t 5-6 ngay, nhng co the
thay oi t 2-15 ngay.
Mc o benh phu thuoc vao nhieu yeu to nh oc lc cua chung vi rut gay benh, loai mac, tuoi,
sc e khang. Cac trieu chng lam sang chu yeu bao gom:
a) The benh nhe, the ho hap: thng gap cac trieu chng nh hat hi, kho th, ho, chay nc
mui, to chc vung mat va co sng; a chay, phan co mau trang xanh hoac mau trang;
b) The benh nang: thng gap cac trieu chng nh suy nhc than kinh, suy nhc c the, run
c, sa canh, ngoeo au va co, quay tron, liet chan, liet toan than; giam e, trng b mong vo, chet
ot ngot; ty le t vong co the len en 100%.
6. Benh tch
Gia cam mac benh thng co cac benh tch nh: viem tui kh day uc, viem va xuat huyet kh
quan, co cac am hoai t da day tuyen, ruot va hach manh trang; xuat huyet iem da day tuyen,
tap trung xung quanh lo o ra cua tuyen tieu hoa; phu, xuat huyet hoac thoai hoa ong dan trng
ga e.
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7. Chan oan phong th nghiem
a) Chan oan phan biet: Can chan oan phan biet benh Niu-cat-xn vi cac benh gia cam khac
nh cum gia cam, viem thanh kh quan, viem phe quan truyen nhiem, nam do Mycoplasma, au
gia cam (the bach hau), hoi chng giam e (EDS-76);
b) Phat hien tac nhan gay benh: s dung phan ng ngng ket hong cau ga (hemagglutination - HA)
va phan ng ngan tr ngng ket hong cau ga (hemagglutination inhibition - HI). Ngoai ra, co the
dung ky thuat PCR;
c) Phat hien khang the: s dung cac phng phap huyet thanh hoc nh phan ng ngan tr
ngng ket hong cau ga (HI) hoac phng phap ELISA;
d) Xac nh oc lc cua chung vi rut gay benh: s dung mot trong cac phng phap sau:
Thi gian trung bnh gay chet phoi trng ga.
Ch so gay benh khi tiem vi rut vao nao cho ga con 1 ngay tuoi.
Ch so gay benh khi tiem vi rut vao tnh mach cho ga 6 tuan tuoi.
Chng II
PHONG BENH NIU-CAT-XN
ieu 5. Tuyen truyen ve phong, chong benh Niu-cat-xn

1. Cuc Thu y xay dng noi dung va to chc thc hien chng trnh tuyen truyen phong, chong
benh Niu - cat - xn. Hng dan Chi cuc Thu y tnh, thanh pho trc thuoc Trung ng (sau ay goi
la Chi cuc Thu y) trien khai chng trnh truyen thong a phng.
cac noi dung ve phong benh Niu - cat - xn.
3. Cac c quan thong tin ai chung, cac to chc oan the to chc tuyen truyen pho bien kien
thc ve benh Niu-cat-xn, tnh chat nguy hiem cua benh, cac bien phap phong chong en tng ho
gia nh co chan nuoi gia cam va cong ong.
4. Tuyen truyen, van ong cac to chc, ca nhan co chan nuoi, buon ban, van chuyen, giet mo
gia cam cam ket thc hien "Ket c phong benh" vi cac noi dung sau:
a) Khong mua, ban, an tht gia cam b benh, chet hoac khong ro nguon goc;
b) Thc hien phong benh Niu-cat-xn bang vac xin;
c) Thc hien khai bao dch kp thi;
d) Khong vt xac gia cam ba bai.
ieu 6. Yeu cau ve ve sinh phong benh
1. Ve chuong trai chan nuoi: phai am bao cac quy nh ve ieu kien chuong trai, ve sinh thu y
oi vi khu vc chan nuoi, chuong nuoi gia cam;
2. Ve con giong: con giong phai am bao cac yeu cau theo quy nh tai Phap lenh Giong vat
nuoi nam 2004; phai co nguon goc ro rang, khoe manh, co giay chng nhan kiem dch ong vat cua
c quan thu y va phai c nuoi cach ly trc khi nhap an;
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3. Ve phng tien van chuyen, con ngi:
Phng tien van chuyen phai c ve sinh, tieu oc kh trung theo quy nh.
Ngi ra vao khu vc chan nuoi phai thc hien ung quy trnh ve sinh, tieu oc kh trung
ca nhan.
ieu 7. Yeu cau ve quan ly chan nuoi gia cam
1. Chan nuoi gia cam phai am bao cac ieu kien ve sinh thu y, chat lng con giong, quy trnh
chan nuoi, quy trnh phong benh theo quy nh phong, chong dch cua c quan thu y.
2. C s chan nuoi gia cam quy mo tap trung t 500 con tr len phai ang ky vi c quan thu y
a phng; phai co can bo thu y quan ly, theo doi. So lng an gia cam, au gia cam phai c
cap nhat t nhat 3 thang mot lan.
3. Khuyen khch viec xay dng vung, c s an toan dch benh oi vi benh Niu-cat-xn.
ieu 8. Phong benh bang vac xin
Thc hien phong benh nh ky bang vac xin theo quy nh tai Quyet nh so 63/2005/Q-
BNN ngay 13/10/2005 cua Bo trng Bo Nong nghiep va Phat trien nong thon quy nh ve tiem
phong bat buoc vac xin cho gia suc, gia cam. Viec phong benh bang vac xin phai c thc hien
thng xuyen, lien tuc nham tao mien dch bao ho cho an gia cam mi phat sinh hoac het thi
gian mien dch.
1. oi tng tiem phong: ga cac loai, chim cut;
2. Pham vi tiem phong: Cac c s chan nuoi tap trung, chan nuoi ho gia nh trong pham vi
ca nc;
3. Thi gian tiem phong: tiem phong nh ky moi nam 2 lan: vao thang 3 4 va thang 9 10,
cac thang tiem phong bo sung cho an ga mi phat sinh. Tuy theo la tuoi ga, loai vac xin co the
nho vac xin vao mat, mui hoac tiem oi vi chan nuoi ho gia nh. oi vi chan nuoi tap trung tiem
phong theo lch;
4. Chi cuc Thu y kiem tra, on oc viec phong benh Niu - cat - xn va hng dan viec cap giay
chng nhan tiem phong.
ieu 9. Giam sat benh Niu-cat-xn
1. Hang nam, Cuc Thu y chu tr xay dng va to chc thc hien chng trnh giam sat benh
Niu-cat-xn;
2. Noi dung giam sat bao gom: giam sat lam sang nham phat hien nhanh o dch, giam sat lu
hanh vi rut va giam sat huyet thanh nham anh gia ty le lu hanh cua tac nhan gay benh, lu hanh
khang the, giam sat s bien oi va anh gia oc lc cua vi rut;
3. Chnh quyen cac cap ch ao cac c quan lien quan ho tr nganh thu y thc hien cac chng
trnh giam sat benh Niu-cat-xn.
ieu 10. Kiem dch va kiem soat van chuyen
1. Kiem dch bien gii: thc hien viec kiem dch, kiem soat van chuyen gia cam, san pham gia
cam qua bien gii theo quy nh.
a) Chnh quyen cac cap ch ao cac c quan chc nang cua a phng phoi hp vi nganh thu
y tang cng cong tac kiem tra, kiem soat, ngan chan, x ly gia cam nhap lau;
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b) Thng xuyen thc hien kh trung, tieu oc moi phng tien van chuyen gia cam, san pham
gia cam khi i qua ca khau.
2. Kiem dch trong nc:
a) Cac c quan thu y thc hien kiem dch gia cam, san pham gia cam tai ni xuat phat va cap
giay chng nhan kiem dch theo quy nh;
b) Cac tram, chot kiem dch ong vat tai cac au moi giao thong co nhiem vu kiem soat
viec van chuyen gia cam, san pham gia cam va x ly cac trng hp vi pham theo quy nh
cua phap luat.
Chng III
CHONG DCH NIU-CAT-XN
ieu 11. Khai bao va x ly o dch au tien nghi mac benh

1. Khi phat hien gia cam co cac bieu hien khac thng nghi mac benh Niu-cat-xn th chu ho
chan nuoi phai khai bao ngay cho c quan thu y ni gan nhat, nhan vien thu y hoac chnh quyen c
s; ong thi cach ly gia cam nghi mac benh.
2. Khi nhan c thong bao co gia cam nghi mac benh Niu-cat-xn, can bo nhan c tin bao
phai tien hanh xac minh va thong bao ngay cho Tram Thu y huyen, ong thi phai bao cao cho Uy
ban nhan dan xa, phng, th tran.
3. Tram Thu y huyen: khi nhan c thong bao cua nhan vien thu y hoac chnh quyen c s
phai nhanh chong to chc kiem tra, chan oan xac minh o dch; hng dan chu ho chan nuoi cac
bien phap cach ly, ve sinh kh trung tieu oc, x ly dch, ong thi lay mau benh pham gi i
xet nghiem theo quy nh.
4. Trong trng hp ket qua chan oan xac nh la o dch Niu-cat-xn. Tram Thu y huyen
hng dan chu vat nuoi thc hien:
a) Tieu huy ga mac benh, nghi mac benh;
b) Tiem phong ga khoe manh trong o dch va khu vc xung quanh;
c) Ve sinh, phun hoa chat kh trung, tuan 2 lan.
5. Trong trng hp can thiet, c quan thu y co the tham mu cho chnh quyen a phng to
chc tieu huy an gia cam mac benh ma khong can ch ket qua xet nghiem.
ieu 12. Chan oan benh
Viec chan oan benh phai c thc hien tai cac phong xet nghiem thuoc Cuc Thu y hoac c
Cuc Thu y uy quyen. Quy trnh xet nghiem theo Tieu chuan Viet Nam.
Chan oan benh Niu-cat-xn can c thc hien chan oan phan biet vi benh cum gia cam
the oc lc cao. Neu xet nghiem xac nh benh Niu-cat-xn am tnh, cum gia cam dng tnh th
ap dung thong t so 69/2005/TT BNN ngay 07/11/2005 cua Bo Nong nghiep va Phat trien nong
thon ve viec Hng dan mot so bien phap cap bach phong, chong dch cum (H5N1) gia cam.
Trng hp ngi gi mau xet nghiem khong phai la can bo thu y thuoc c quan thu y co tham
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quyen cua a phng, phong xet nghiem co trach nhiem thong bao ngay ve o dch nghi ng cho
c quan thu y a phng ni nghi co dch e to chc giam sat, theo doi.
Khi co ket qua xet nghiem xac nhan o dch Niu-cat-xn, phong xet nghiem phai thong bao
ngay cho Chi cuc Thu y ni co o dch e to chc chong dch, ong thi thong bao ket qua cho
ngi gi mau.
ieu 13. Cong bo dch
1. ieu kien cong bo dch:
Khi co u cac ieu kien th Chu tch Uy ban nhan dan cap tnh cong bo dch theo quy nh tai
ieu 17, ieu 19, ieu 20 cua Phap lenh Thu y.
2. Pham vi cong bo dch
a) Khi co nhieu ho gia nh (tren 5%) trong mot xa co gia cam mac benh Niu-cat-xn the oc
lc cao th cong bo xa o co dch;
b) Khi co t 30% so xa tr len trong mot huyen co dch th cong bo dch tren a ban toan huyen.
3. Trong trng hp khong cong bo dch hoac gia cam mac benh Niu-cat-xn the oc lc thap
th c quan thu y a phng ch ao ap dung cac bien phap phong, chong dch theo quy nh tai
ieu 13 cua Thong t nay.
ieu 14. Cac bien phap x ly oi vi vung dch
1. Trong trng hp xac nh vung dch do vi rut the oc lc cao gay ra th ap dung cac bien
phap x ly nh sau:
a) Tieu huy ngay gia cam chet, gia cam mac benh; cach ly nhng con gia cam khoe manh trong
an e cham soc nuoi dng hoac giet mo tieu thu tai cho;
b) S dung vac xin Niu-cat-xn phong benh cho an ga;
c) oi vi an ga chan nuoi quy mo nho cha mac benh nhng nam trong pham vi o dch: to chc
nuoi cach ly tai cho; tang cng cham soc nuoi dng; khuyen khch giet mo e tieu thu tai cho;
d) oi vi an gia cam chan nuoi tap trung vi so lng ln nam trong pham vi o dch, nhng
cha mac benh th cho phep giet mo tai c s do c quan thu y cap tnh ch nh;
) Ve sinh, tieu oc kh trung:
Ve sinh: Thu gom chat thai ran e ot hoac chon; ra nen chuong, dung cu chan nuoi bang nc
xa phong hoac chat tay ra. oi vi chat thai long phai c x ly bang hoa chat.
Tieu oc, kh trung: Sau khi don ra, ve sinh c gii, e kho va tien hanh tieu oc kh trung
khu vc chuong nuoi, dung cu chan nuoi, khu vc tieu huy hoac chon gia cam.
Ngi tham gia qua trnh x ly, tieu huy gia cam mac benh Niu-cat-xn phai s dung bao ho lao
ong phu hp va ve sinh tieu oc kh trung ca nhan khi ket thuc cong viec.
2. Trong trng hp o dch c xac nh la do vi rut the oc lc thap gay ra th ap dung cac
bien phap x ly nh sau:
a) Cach ly gia cam mac benh, to chc cham soc nuoi dng nang cao sc khoe cho an gia cam;
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b) To chc ieu tra, giam sat dch tren an gia cam cua ca thon;
c) S dung vac xin Niu-cat-xn phong benh cho an ga;
d) Nghiem cam viec van chuyen, buon ban gia cam benh trong pham vi 21 ngay tnh t ngay
cuoi cung an gia cam mac benh c x ly.
ieu 15. Kiem soat van chuyen khi co dch
1. Tha uy quyen cua Chu tch Uy ban nhan dan tnh, Chu tch Uy ban nhan dan huyen ra
quyet nh thanh lap chot kiem dch, e kiem soat van chuyen gia cam, san pham gia cam ra,
vao vung dch. Chot kiem dch phai co u phng tien va hoa chat sat trung e x ly moi oi
tng ra khoi vung co dch.
2. Gia cam khoe manh c phep van chuyen trong cac trng hp sau:
a) Nhng an gia cam khoe manh c phep giet mo, tieu thu trong pham vi xa;
b) Nhng an gia cam cua c s chan nuoi tap trung vi so lng ln c phep van chuyen
bang cac phng tien chuyen dung en thang c s giet mo do Chi cuc Thu y tnh ch nh. Viec
van chuyen phai co s giam sat cua c quan thu y a phng;
c) Gia cam nuoi trong cac c s an toan dch oi vi benh Niu-cat-xn c phep van chuyen,
tieu thu bnh thng trong pham vi tnh.
ieu 16. Cong bo het dch va chan nuoi tr lai cac c s a co dch xay ra
1. Chu tch Uy ban nhan dan cap tnh ra quyet nh cong bo het dch khi co u cac ieu kien sau ay:
a) Tat ca an ga trong dien phai tiem phong thuoc vung dch, vung b dch uy hiep a c s
dung vac xin phong benh Niu-cat-xn va a co mien dch;
b) a qua 21 ngay ke t ngay con ga cuoi cung b chet hoac b tieu huy, khong co con ga nao
khac b mac benh hoac b chet v benh Niu-cat-xn;
c) a thc hien ve sinh, kh trung tieu oc 2 lan/tuan lien tuc trong 2 tuan oi vi ho chan nuoi,
c s chan nuoi a b dch, vung co dch;
d) Chi cuc Thu y cap tnh kiem tra xac nhan a u ieu kien cong bo het dch theo quy nh tai
cac iem a, b, c khoan nay va co van ban e ngh cong bo het dch.
2. ieu kien chan nuoi tr lai:
a) a thc hien ve sinh, kh trung, tieu oc;
b) e trong chuong trong thi gian toi thieu la 21 ngay. Trc khi nuoi tr lai, c s chan nuoi
phai c ve sinh, phun thuoc tieu oc kh trung trc khi nuoi;
c) Ga a vao nuoi tr lai phai biet ro nguon goc, a c s dung vac xin phong benh
Niu-cat-xn theo quy nh;
d) Sau khi nuoi tr lai, can phai giam sat chat che, lien tuc trong vong 40 ngay (theo quy trnh
giam sat cua OIE) e e phong mam benh tai xuat hien va gay benh tr lai.
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Chng IV
TO CHC THC HIEN

1. Trach nhiem cua Cuc Thu y
a) Xay dng Chng trnh quoc gia phong, chong benh Niu-cat-xn gia cam e trnh cap
co tham quyen phe duyet; to chc kiem tra, on oc, hng dan viec thc hien Chng trnh
cac a phng.
b) To chc xay dng, hng dan va kiem tra viec thc hien ke hoach tiem phong, giam sat phat
hien benh Niu-cat-xn cac a phng.
c) To chc thanh tra, kiem tra tren pham vi toan quoc ve cong tac phong chong benh Niu-cat-xn.
2. Trach nhiem cua Cuc Chan nuoi
a) Xay dng e an quy hoach chan nuoi gia cam e trnh cap co tham quyen phe duyet; to chc
kiem tra, on oc, hng dan viec thc hien e an quy hoach chan nuoi cac a phng;
b) Hng dan viec ang ky quan ly chan nuoi gia cam tai a phng;
c) Xay dng tai lieu hng dan va tuyen truyen ngi chan nuoi thc hanh chan nuoi am bao
ve sinh moi trng va an toan sinh hoc.
ieu 18. Trach nhiem cua c quan nha nc, to chc, ca nhan a phng
1. Trach nhiem cua Uy ban nhan dan cap tnh
a) Ch ao S Nong nghiep va Phat trien nong thon, cac ban nganh co lien quan a phng
xay dng e an quy hoach phat trien chan nuoi, Chng trnh phong, chong benh Niu-cat-xn va
hng dan xay dng vung, c s an toan benh Niu-cat-xn tai a phng.
b) To chc xay dng va thc hien ke hoach tiem phong, giam sat phat hien benh Niu-cat-xn
cua a phng.
c) Cung co he thong thu y a phng nham ap ng yeu cau phong, chong dch Niu-cat-xn.
d) Ch ao cac s, ban nganh, oan the tai a phng thng xuyen trien khai cong tac thong
tin tuyen truyen phong chong benh Niu-cat-xn.
2. Trach nhiem cua S Nong nghiep va Phat trien nong thon
a) Xay dng e xuat, trnh Uy ban nhan dan tnh e an quy hoach phat trien chan nuoi,
Chng trnh phong, chong benh Niu-cat-xn va hng dan xay dng vung, c s an toan benh
Niu-cat-xn tai a phng.
b) Thng xuyen to chc kiem tra, on oc cong tac phong chong benh Niu-cat-xn cua tnh.
3. Trach nhiem cua Chi cuc Thu y cap tnh
a) To chc trien khai va trc tiep ch ao cong tac phong, chong benh Niu-cat-xn tren a ban
tnh, thanh pho; d tru kinh ph phong, chong benh Niu-cat-xn tren a ban tnh
b) Thc hien che o bao cao ot xuat khi co dch xay ra va bao cao nh ky tnh hnh dch benh,
phong benh bang vac xin ve Cuc Thu y.
4. Trach nhiem cua Uy ban nhan dan cap huyen
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a) Phoi hp vi Chi cuc Thu y tnh ch ao Tram Thu y huyen, cac ban, nganh, to chc, ca
nhan co lien quan a phng thc hien cac bien phap phong chong benh Niu-cat-xn tren a
ban huyen.
b) Huy ong lc lng phuc vu cong tac phong chong benh, ac biet cong tac tiem phong, tieu
huy gia cam mac benh.
c) Cap ngan sach a phng cho cong tac phong chong dch cua huyen.
5. Trach nhiem cua Phong Nong nghiep, Phong Kinh te, Tram Thu y
a) Trc tiep to chc thc hien cong tac phong chong benh Niu-cat-xn tai huyen;
b) Hng dan ky thuat cac bien phap phong chong en tan xa, thon.
c) Bao cao kp thi nhu cau ve kinh ph, vat t hoa chat, vac xin, lao ong, cho Uy ban nhan dan
huyen va Chi cuc Thu y.
d) Hang thang bao cao cong tac phong, chong benh Niu-cat-xn ve Chi Cuc Thu y vi cac noi
dung: so gia cam, ket qua tiem phong, tnh hnh benh Niu-cat-xn (neu co) cua cac huyen.
6. Trach nhiem cua Uy ban nhan dan cap xa
a) Thanh lap Ban ch ao phong chong dch gia suc, gia cam cap xa, trong o co benh
Niu - cat - xn va cac benh a co trc nh benh cum gia cam, tai xanh va l mom long
mong do Chu tch Uy ban nhan dan lam Trng ban vi s tham gia cua cap uy ang, chnh
quyen, oan the va can bo thu y, y te, nong nghiep.
b) Bo tr to chuyen mon e hng dan ky thuat, thng trc va tong hp tnh hnh nuoi gia cam,
ket qua tiem phong, quan ly an gia cam.
c) Ch ao Trng thon trc tiep kiem tra, giam sat tnh hnh dch benh; phoi hp vi cac to
chc oan the quan chung (oan Thanh nien, Hoi Phu n, Hoi Nong dan, Hoi Cu chien binh
va cac to chc oan the khac) tuyen truyen van ong nhan dan nang cao nhan thc ve tnh chat
nguy hiem cua benh Niu-cat-xn trong chan nuoi gia cam va tch cc tham gia chien dch tiem
phong, quan ly an gia cam nuoi. Moi thon to chc ky cam ket thc hien ket c phong benh
theo quy nh tai khoan 4 ieu 5 cua Thong t nay.
d) Thanh lap oi xung kch chong dch, gom dan quan t ve, thanh nien, can bo thu y, cong an
e tieu huy gia cam b benh, ve sinh tieu oc kh trung, giam sat ngi ra vao o dch, trc gac tai
7. Trach nhiem cua nhan vien thu y xa, cong tac vien thu y xa.
a) Giam sat phat hien benh Niu-cat-xn en tan ho chan nuoi, c s chan nuoi tren a ban xa
va bao cao kp thi cho Uy ban nhan dan xa va Tram Thu y huyen;
b) Trc tiep tham gia cong tac phong chong benh, trc tiep tiem phong vac xin.
8. Trach nhiem cua trng thon, ap hoac to trng dan pho
Quan ly trc tiep an gia cam tai thon, ap, to dan pho; phoi hp vi Thu y vien thon, ap, xa,
phng pho bien, hng dan cac to chc, ca nhan nuoi gia cam; tham gia cong tac phong, chong
benh Niu-cat-xn tai a phng.
ieu 19. Trach nhiem cua chu ho chan nuoi gia cam
1. am bao ieu kien chan nuoi gia cam hp ve sinh; thc hien cac bien phap phong, chong
benh Niu-cat-xn theo hng dan cua can bo thu y, chnh quyen a phng.
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2. Bao ngay cho can bo thu y xa hoac trng thon, ap, to trng dan pho khi nghi ng co benh
Niu-cat-xn.
3. Chu ho chan nuoi chu moi trach nhiem khi e gia cam tha rong, lam lay lan dch benh
Niu-cat-xn sang cac ho chan nuoi gia cam khac.
ieu 20. Hieu lc thi hanh
Thong t nay co hieu lc thi hanh sau 45 ngay ke t ngay ky;
Trong qua trnh thc hien, neu co vng mac hoac can bo sung, sa oi, e ngh bao cao ve Bo
Nong nghiep va Phat trien nong thon e xem xet, x ly./.

- Thu tng, cac Pho Thu tng (e b/c);
- Van phong TW ang; TH TRNG
- Van phong Chnh phu;
- Ban Ch ao quoc gia PCBD;
- Lanh ao Bo;
- Cac Bo, nganh lien quan;
- UBND cac tnh, TP;
- Cac n v thuoc Bo;
- S Nong nghiep va PTNT cac tnh, TP;
- Chi cuc Thu y cac tnh, TP;
- Cong bao CP; Diep Knh Tan
- Lu: VT, TY.
137
******** ********
QUYET NH
BAN HANH QUY NH PHONG, CHONG
HOI CHNG ROI LOAN SINH SAN VA HO HAP LN (PRRS)
Can c Phap lenh Thu y ban hanh ngay 29/4/2004;

Can c Ngh nh so 33/2005/N - CP ngay 15/3/2005 cua Chnh phu Quy nh chi tiet thi hanh
Can c Ngh nh so 01/2008/N - CP ngay 03/01/2008 cua Chnh phu quy nh chc nang,
nhiem vu, quyen han va c cau to chc cua Bo Nong nghiep va Phat trien nong thon;
Can c Quyet nh so 719/Q-TTg ngay 05/6/2008 cua Thu tng Chnh phu ve chnh sach ho
tr phong, chong dch benh gia suc, gia cam;
Theo e ngh cua Cuc trng Cuc Thu y,
QUYET NH:
ieu 1. Ban hanh kem theo Quyet nh nay Quy nh phong, chong Hoi chng roi loan sinh
san va ho hap ln (PRRS).
ieu 2. Quyet nh nay co hieu lc sau 15 ngay, ke t ngay ang Cong bao Chnh phu.
ieu 3. Chanh Van phong Bo, Vu trng Vu Phap che, Cuc trng Cuc Thu y, Thu trng cac
n v co lien quan va Giam oc S Nong nghiep va Phat trien nong thon cac tnh, thanh pho trc
thuoc Trung ng chu trach nhiem thi hanh Quyet nh nay./.

- Nh ieu 3;
- Van phong Chnh phu; TH TRNG
- Cong bao VPCP, Website Chnh phu;
- Bo trng, cac Th trng Bo NN & PTNT;
- Uy ban nhan dan cac tnh, thanh pho;
- Cuc Kiem tra van ban (Bo T phap);
- S NN&PTNT cac tnh, thanh pho; Bui Ba Bong
- Chi cuc Thu y cac tnh, thanh pho;
- Cac n v lien quan thuoc Bo;
- Lu VT, PC.
138
QUY NH
PHONG CHONG HOI CHNG ROI LOAN SINH SAN VA HO HAP LN (PRRS)
(Ban hanh theo Quyet nh so: 80 /2008/Q-BNN ngay 15 /7 /2008 cua
Bo trng Bo Nong nghiep va Phat trien nong thon)
Chng 1:
NHNG QUY NH CHUNG
ieu 1. Pham v ieu chnh va oi tng ap dung

1. Quy nh nay quy nh ve viec phong chong Hoi chng roi loan sinh san va ho hap ln (PRRS).
2. Quy nh nay ap dung oi vi cac c quan nha nc; to chc, ca nhan Viet Nam, to chc, ca
nhan nc ngoai co hoat ong ve chan nuoi, buon ban, giet mo, van chuyen, kinh doanh ln tren
lanh tho Viet Nam.
Trong quy nh nay, cac t ng di ay c hieu nh sau:
1. Hoi chng roi loan sinh san va ho hap ln (ten tieng Anh la Porcine Reproductive and
Respiratory Syndrome = PRRS) sau ay goi la benh Tai xanh.
2. O dch Tai xanh la ni co mot hoac nhieu ln mac benh Tai xanh.
3. Vung dch la mot hoac nhieu xa, phng, th tran (sau ay goi chung la xa) co dch.
4. Vung b dch uy hiep la cac xa tiep giap vi cac xa thuoc vung dch.
5. Vung em la cac xa tiep giap ben ngoai cac xa thuoc vung b dch uy hiep.
6. Vung nguy c cao la cac xa co ch buon ban ln va cac san pham co nguon goc t ln hoac
c s giet mo ln, ni tap trung ln e chuyen i ni khac, cac xa co ng quoc lo i qua.
ieu 3. ac iem chung cua benh
1. Benh Tai xanh la benh truyen nhiem cap tnh nguy hiem ln moi la tuoi, benh lay lan
nhanh, lam om va co the gay chet nhieu ln. Ln nhiem benh Tai xanh thng b suy giam mien
dch, do o tao ieu kien cho nhieu loai dch benh khac ke phat nh Dch ta ln, Pho thng han,
Tu huyet trung, E. Coli, Lien cau khuan, Mycoplasma, ay la nhng nguyen nhan ke phat gay
chet nhieu ln benh, gay ra nhng ton that ln ve kinh te cho ngi chan nuoi. Hien nay, benh nay
a lay lan va tr thanh dch a phng nhieu nc tren the gii, ke ca cac nc co nganh chan
nuoi ln phat trien. Viet Nam, benh Tai xanh a xuat hien tai nhieu a phng, gay thiet hai
nghiem trong ve kinh te, anh hng en an sinh xa hoi.
2. Tac nhan gay benh: Benh Tai xanh la do mot loai vi rut PRRS thuoc giong Arterivirus, ho
Arteriviridae, bo Nidovirales, co cau truc vo boc dang chuoi n RNA. Hien nay, da tren viec phan
tch cau truc gien va khang nguyen, cac nha khoa hoc a xac nh c 2 chung (typ): typ I gom nhng
vi rut thuoc dong Chau Au va typ II gom nhng vi rut thuoc dong Bac My. Vi rut typ II gay benh tram
trong hn cac nc Chau A. Nhng nghien cu gan ay cho thay, vi rut gay benh Tai xanh ton tai di
hai dang, dang co ien co oc lc thap va dang bien the co oc lc cao, gay nhiem va chet nhieu ln.
139
3. S ton tai cua vi rut va ng truyen lay: Vi rut co trong dch mui, nc bot, phan, nc tieu
cua ln mac benh hoac mang trung va phat tan ra moi trng. cac loai ln man cam, vi rut co
thi gian ton tai va c bai thai ra ngoai moi trng tng oi dai: ln mang trung va khong co
trieu chng lam sang, vi rut co the c phat hien nc tieu trong 14 ngay, phan khoang 28-
35 ngay, huyet thanh khoang 21-23 ngay, dch hau hong khoang 56-157 ngay, tinh dch sau
92 ngay va ac biet huyet thanh cua ln b nhiem benh sau 210 ngay van co the tm thay vi rut.
Sc e khang cua vi rut: ieu kien moi trng co o pH < 5.5 hoac > 6.5 vi rut gan nh mat
tnh gay benh; nhiet o 40C vi rut ton tai c 120 gi, 200C ton tai trong 20 gi, 370C ton tai
c 3 gi, 560C ton tai c trong vong 6 phut. Vi rut cung de dang b tieu diet bi cac hoa chat
sat trung thong thng nh: voi bot, chlorine, formon, iodine
Vi rut co the phat tan, lay lan thong qua cac hnh thc: (1) trc tiep: tiep xuc vi ln mac benh,
ln mang trung, phan, nc tieu, bui, bot nc, thu tinh nhan tao va co the do ln rng; (2) gian
tiep: dung cu chan nuoi, phng tien van chuyen va dung cu bao ho lao ong mang trung. Hnh
thc phat tan qua khong kh (t phan, chat thai mang vi rut), theo gio (co the i xa ti 3 km), nguon
nc b o nhiem.
4. Trieu chng lam sang:
a) Ln nai giai oan can sa: Khi b nhiem vi rut, ln thng bieng hoac bo an t 7-14 ngay, sot
tren 400C, thng say thai vao giai oan cuoi, e non, ong c gia, nh duc hoac cham ong duc
tr lai sau khi e, ho va viem phoi.
b) Ln nai giai oan e va nuoi con: Bo an hoac an t, li uong nc, l hoac hon me, mat
sa va viem vu, e sm khoang 2-3 ngay, thai go, ln con chet ngay sau khi sinh, ln con yeu, tang
ty le thai chet hoac yeu, tang so thai go, chet lu trong giai oan 3 tuan cuoi trc khi sinh, mot
vai an con so nay co the ti 30% tong so ln con sinh ra. Ty le chet an con co the ti 70%
tuan th 3-4 sau khi xuat hien trieu chng. Roi loan sinh san co the keo dai 4-8 thang trc khi tr
lai bnh thng.
c) Ln c giong: Bo an hoac an t, sot tren 400C, an hoac hon me, giam hng phan, mat
tnh duc, lng tinh dch t, chat lng tinh kem va cho ln con sinh ra nho.
d) Ln con theo me: Nhieu con chet yeu sau khi sinh, nhng con song sot sau co the trang gay
yeu, nhanh chong ri vao trang thai tut ng huyet do khong bu c, mat co d mau nau, tren da
co vet phong rop, tieu chay nhieu, tang nguy c mac cac benh ve ho hap, chan choai ra, i run ray.
) Ln con cai sa va ln choai: Bo an hoac an t, sot tren 400C, ho nhe, long x xac... tuy nhien,
mot so an co the khong co trieu chng. Ngoai ra, trong trng hp ghep vi benh khac co the
thay viem phoi cap tnh, hnh thanh nhieu o ap-xe, the trang gay yeu, da xanh, tieu chay, ho nhe,
hat hi, chay nc mat, th nhanh.
5. Benh tch: Benh tch ac trng nhat la phoi: phoi viem hoai t va tham nhiem ac trng bi
nhng am chac, ac (nhuc hoa) tren cac thuy phoi, cuong phoi cha ay dch viem sau bot, tren
mat cat ngang cua thuy benh loi ra, kho, thuy b benh co mau xam o. Nhieu trng hp viem phe
quan phoi hoa mu mat di thuy nh.
Ngoai ra, benh tch cung co the thay nh: than xuat huyet inh ghim, hach amidan sng, sung
huyet, nao sung huyet, hach mang treo ruot xuat huyet, loet van hoi manh trang.
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Chng 2
PHONG BENH
ieu 4. Tuyen truyen ve phong benh
1. Cuc Thu y xay dng va to chc thc hien cac noi dung chng trnh truyen thong phong,
chong benh Tai xanh, ong thi hng dan Chi cuc Thu y tnh, thanh pho trc thuoc Trung ng
(sau ay goi la Chi cuc Thu y) trien khai chng trnh truyen thong a phng.
thong tin tuyen truyen tai a phng theo noi dung tuyen truyen cua cac c quan thu y.
3. Cac c quan thong tin ai chung, c quan, n v chuyen mon va cac to chc oan the to chc
tuyen truyen pho bien kien thc ve benh Tai xanh, tnh chat nguy hiem cua benh va bien phap
phong chong ti tng ho gia nh va cong ong.
4. Tuyen truyen, van ong cac to chc, ca nhan chan nuoi trong tng thon ky cam ket thc
hien "5 khong":
a) Khong giau dch;
b) Khong mua ln benh, san pham cua ln benh;
c) Khong ban chay ln benh;
d) Khong van chuyen ln benh ra khoi vung dch;
) Khong vt ba bai xac ln benh ra moi trng.
ieu 5. Chu ong giam sat, phat hien sm dch
1. Cuc Thu y co trach nhiem:
a) Xay dng ke hoach giam sat dch benh Tai xanh qua tng giai oan; hang nam to chc thc
hien va hng dan, ch ao cac Chi cuc Thu y trien khai cac noi dung giam sat dch benh; kiem tra,
giam sat viec thc hien cua cac a phng trong ca nc.
b) Tap hp, phan tch so lieu dch te, lap ban o dch te benh trong pham vi ca nc;
2. Chi cuc Thu y co trach nhiem:
a) Xay dng ke hoach giam sat dch benh theo hng dan cua Cuc Thu y e trnh cac cap co
tham quyen phe duyet va to chc thc hien ke hoach giam sat dch benh tai a phng.
b) Lap ban o dch te benh tai a phng e tham mu cho chnh quyen cac cap cac bien phap
phu hp, chu ong phong chong dch.
c) To chc lay mau benh pham e chan oan, giam sat dch benh ot xuat hoac thng xuyen
theo hng dan cua Cuc Thu y.
d) Kiem soat chat che ln nhap vao a phng.
3. Uy ban nhan dan xa co trach nhiem
a) Phan cong trach nhiem cho trng thon, ap (sau ay goi chung la thon), nhan vien thu y
xa giam sat dch benh; lap so theo doi tnh hnh chan nuoi, dch benh, ket qua tiem phong cac
benh ln tai a phng;
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b) Ho tr cac c quan thu y co tham quyen to chc lay mau benh pham.
4. Ngi chan nuoi co trach nhiem:
a) Thc hien nghiem chnh cac quy nh ve sinh thu y trong chan nuoi va hng dan cua can
bo thu y.
b) Khi phat hien ln co nhng bieu hien bat thng, bo an hoac an t, sot cao, say thai th bao
ngay cho nhan vien thu y xa, trng thon. Nghiem tuc thc hien 5 khong theo quy nh tai khoan
4 ieu 4 cua Quy nh nay.
c) Co so theo doi tnh hnh chan nuoi, theo doi tiem vac xin phong cac benh cua ln theo quy
nh tai Quyet nh so 63/2005/Q-BNN ngay 13/10/2005 cua Bo Nong nghiep va Phat trien nong
thon va hng dan bo sung cua Cuc Thu y (sau ay goi tat la theo quy nh).
ieu 6. Ve sinh phong benh
1. Khu chan nuoi
a) oi vi cac trang trai, gia trai phai am bao ieu kien ve sinh thu y theo quy nh tai ieu
7, Chng 2, Ngh nh 33/2005/N-CP ngay 15/3/2005 quy nh chi tiet thi hanh mot so ieu
cua Phap lenh Thu y.
b) oi vi cac ho gia nh: Khong c nuoi tha rong, chuong nuoi phai c che chan, cach ly,
nen chuong phai cao rao va am bao cac ieu kien ve sinh thu y.
c) Hang ngay phai thc hien ve sinh c gii va nh ky hang tuan thc hien tieu oc kh trung
chuong trai, dung cu chan nuoi, phng tien van chuyen bang hoa chat sat trung thong thng nh:
voi bot, chlorine, formon, iodine hoac cac loai thuoc sat trung khac theo hng dan cua nha san xuat.
2. Con giong
a) Con giong a vao chan nuoi phai khoe manh, co nguon goc, co giay chng nhan kiem dch
cua c quan thu y. Trc khi nhap an phai c nuoi cach ly, theo doi 21 ngay.
b) Thng xuyen cham soc, nang cao sc khoe cho con vat thong qua che o dinh dng hp ly,
tiem phong ay u cac loai vac xin theo quy nh;
c) Rieng oi vi ln mua ve vi muc ch lam con giong (ln c giong, ln nai), ngoai viec
thc hien cac quy nh tai iem a va b cua khoan nay, c s chan nuoi phai bao cho c quan thu y
co tham quyen tai a phng biet e nh ky kiem tra benh theo quy nh.
3. Thc an, nc uong phai am bao tieu chuan ve sinh thu y
4. Phng tien van chuyen ln va san pham cua ln phai c ve sinh, tieu oc kh trung theo
quy nh.
5. Ngi ra vao khu vc chan nuoi phai s dung trang b bao ho phu hp; thc hien ung quy
trnh ve sinh, tieu oc kh trung.
ieu 7. Phong benh bang thuoc va vac xin
1. Cuc Thu y hng dan cu the viec s dung vac xin phong benh Tai xanh;
2. Ngi chan nuoi chu ong tiem vac xin phong cac benh cho ln theo quy nh; s dung cac
loai thuoc tang sc e khang cho ln.
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ieu 8. Kiem dch van chuyen
1. Van chuyen trong nc
a) Chu tch Uy ban nhan dan tnh, thanh pho trc thuoc Trung ng (sau ay goi la Uy ban nhan
dan tnh) quyet nh thanh lap tram, chot kiem dch tam thi tai au moi giao thong theo e ngh
cua S Nong nghiep va Phat trien nong thon khi cac tnh lien ke co dch;
b) Chi cuc Thu y chu trach nhiem thc hien viec kiem dch ln, san pham cua ln tai ni xuat
phat va cap giay chng nhan kiem dch theo quy nh.
c) Cac Tram, chot kiem dch ong vat tai cac au moi giao thong thc hien nh sau:
- Kiem soat chat che ln, san pham ln van chuyen qua cac tram, chot kiem dch; thu gi, tieu
huy ln, san pham ln mac benh hoac khong co giay chng nhan kiem dch;
- oi vi ln, san pham cua ln co giay chng nhan kiem dch nhng khong hp le th thc hien
viec kiem dch, cap giay chng nhan kiem dch va thong bao cho Chi cuc Thu y ni tiep nhan biet.
- oi vi ln, san pham cua ln c van chuyen bang phng tien khong am bao ve sinh thu
y, khong c niem phong, khong anh dau theo quy nh th yeu cau chu hang khac phuc bang
cach s dung phng tien van chuyen khac am bao ve sinh thu y va thc hien niem phong phng
tien van chuyen, anh dau ln theo ma so cua Chi cuc, ong thi thong bao cho Chi cuc ni tiep
nhan biet.
- X phat nghiem cac trng hp vi pham theo quy nh cua phap luat.
d) Chi cuc Thu y ni tiep nhan phai kiem soat chat che ln, san pham cua ln nhap vao tnh va
x ly nghiem cac trng hp vi pham theo quy nh tai iem c khoan 1 ieu nay.
) To chc, ca nhan vi pham cac quy nh ve kiem dch van chuyen b x phat vi pham hanh
chnh va phai chu moi chi ph cho viec kiem dch, x ly ln va san pham cua ln.
2. Van chuyen qua bien gii
a) Chu tch Uy ban nhan dan cac tnh bien gii ch ao cac cap, cac nganh tang cng cong tac
kiem tra, kiem soat, ngan chan, x ly ln va san pham cua ln nhap lau vao trong nc.
b) Uy ban nhan dan tnh quyet nh thanh lap cac chot kiem dch tai cac xa bien gii;
c) Kh trung moi phng tien van chuyen qua ca khau.
Chng 3
CHONG DCH
ieu 9. Khai bao va x ly oi vi o dch au tien nghi mac benh
1. Ngi chan nuoi khi phat hien ln co cac dau hieu bat thng nh sot cao, bo an hoac an t,
say thai hoac chet phai thc hien nh sau:
a) Bao ngay cho nhan vien thu y xa hoac trng thon;
b) Nhot rieng ln mac benh ra khu vc khac;
c) Bo sung cac loai thuoc tang sc e khang, thc an giau dinh dng cho an ln;
143
d) Hang ngay ve sinh, tieu oc kh trung khu vc chan nuoi;
) Khong ban hoac van chuyen ln, san pham cua ln benh ra khoi khu vc chan nuoi khi cha
co ket luan cua c quan thu y co tham quyen.
2. Nhan vien thu y xa, can bo Tram Thu y huyen, quan, th xa, thanh pho thuoc tnh (sau ay
goi la Tram Thu y huyen) khi nhan c thong bao, phai en kiem tra, xac minh ngay; hng dan
ngi chan nuoi cac bien phap cach ly ln mac benh, ve sinh, kh trung tieu oc, cham soc tang
cng sc e khang cho an ln.
3. Tram Thu y huyen lay mau benh pham gi xet nghiem oi vi an ln au tien mac benh
trong pham vi huyen, ong thi bao ngay cho c quan thu y cap tren e e xuat vi Uy ban nhan
dan tnh hoac Uy ban nhan dan cap di c uy quyen quyet nh tieu huy theo quy nh tai khoan
1 ieu 12 cua Quy nh nay ma khong ch ket qua xet nghiem.
ieu 10. Chan oan benh
1. Cuc Thu y hng dan cu the quy trnh lay mau va chan oan benh.
2. oi vi o dch au tien xay ra tren a ban huyen th Tram Thu y huyen phai lay mau
benh pham gi C quan Thu y vung hoac Trung tam Chan oan Thu y Trung ng chan oan
xac nh benh.
Cac o dch sau o, neu phat hien ln co nhng trieu chng, benh tch ien hnh cua benh
Tai xanh th trien khai ngay cac bien phap chong dch ma khong nhat thiet phai lay mau xet
nghiem benh.
ieu 11. Cong bo dch
1. ieu kien cong bo
oi vi cac tnh co dch: Khi co u cac ieu kien th cong bo dch theo quy nh tai ieu 17
cua Phap lenh Thu y nam 2004, Chu tch Uy ban nhan dan cap tnh ra quyet nh cong bo vung
dch, ong thi cong bo vung b dch uy hiep, vung em theo quy nh tai ieu 19 va ieu 20
cua Phap lenh Thu y.
2. Pham vi cong bo dch:
a) Khi co dch tai mot thon th cong bo xa co dch.
b) Khi co t 03 xa tr len trong mot huyen co dch th cong bo dch tren a ban toan huyen.
c) Khi co t 03 huyen tr len trong mot tnh co dch th cong bo dch tren a ban toan tnh.
3. oi vi cac tnh tiep giap tnh co dch: Khi nhan c thong tin ve tnh hnh dch benh, Chi
cuc Thu y xac nh va e ngh Chu tch Uy ban nhan dan tnh ra quyet nh cong bo vung b dch
uy hiep, vung em va ap dung cac bien phap phong, chong dch theo quy nh.
ieu 12. Cac bien phap x ly oi vi o dch
1. X ly o dch:
a) Tieu huy ngay ln chet do benh.
b) oi vi o dch au tien: tieu huy ngay toan bo ln trong o chuong co ln benh.
c) oi vi cac o dch nho le mi xay ra tren a ban: tieu huy ngay toan bo ln benh, cach ly
triet e ln cha b benh e theo doi.
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d) oi vi trng hp dch xay ra dien rong: tieu huy so ln mac benh nang khong ch ket
qua xet nghiem (ln mac benh nang la nhng ln co benh, a c cham soc tch cc, c ho tr
tang cng sc e khang trong vong 7 ngay nhng khong co kha nang bnh phuc), ln mac benh
nhe nuoi cach ly triet e vi ln cha b benh e theo doi chat che dien bien benh.
) Ngi chan nuoi co ln b tieu huy trong cac trng hp tren c ho tr theo Quyet nh so
719/Q-TTg ngay 05/6/2008 cua Thu tng Chnh phu.
2. Ve sinh, tieu oc kh trung:
a) Ve sinh: Thu gom chat thai ran e ot hoac chon; ra nen chuong, dung cu chan nuoi bang
nc xa phong. oi vi chat thai long phai c x ly bang hoa chat. Cong viec nay do ngi chan
nuoi thc hien.
b) Tieu oc kh trung: Sau khi ve sinh c gii, e kho va tien hanh tieu oc kh trung bang hoa
chat phu hp oi vi chuong trai, khu vc chan nuoi, loi ra vao, khu vc tap trung ln e tieu huy,
khu vc tieu huy hoac chon ln, ng lang, ngo xom, ni cong cong. Cong viec nay do oi chong
dch cua xa thc hien.
c) Ngi tham gia qua trnh x ly, tieu huy ln phai s dung bao ho lao ong phu hp va ve
sinh, tieu oc kh trung.
3. Viec tieu huy, chon lap ln thc hien theo van ban hng dan so 561/TY-KH ngay 16/4/2008
cua Cuc Thu y.
4. To chc chong dch theo quy nh tai ieu 18 cua Ngh nh so 33/2005/N- CP ngay
15/3/2005 cua Chnh phu.
ieu 13. Cac bien phap x ly oi vi cac an ln cha b benh trong vung dch ln;
1. oi vi c s chan nuoi nho le va chan nuoi tht quy mo tap trung:
a) Ap dung nghiem ngat cac bien phap chan nuoi an toan sinh hoc.
b) Tang cng cham soc, nuoi dng, nang cao sc e khang cho ln.
2. oi vi cac c s chan nuoi ln giong:
a) Tang cng cham soc, nuoi dng, to chc theo doi, giam sat chat che an
b) Lay mau tinh dch cua tat ca ln c giong va mau huyet thanh cua ln nai e xet nghiem
theo ty le lu hanh c tnh 10% tong an.
Neu toan bo so mau xet nghiem am tnh, cac c s giong tiep tuc c phep sanxuat;
Tieu huy bat buoc vi nhng con dng tnh theo s hng dan va giam sat cua thu y. Sau 7-10
ngay tiep tuc lay mau lan 2 theo ty le lu hanh.
Neu tat ca mau xet nghiem lan 2 cho ket qua am tnh, cac c s giong tiep tuc c phep san
xuat. Neu co them mau dng tnh th khong c san xuat con giong.
c) C s chan nuoi ln giong chu trach nhiem chi tra chi ph cho viec xet nghiem xac nh s
lu hanh cua vi rut Tai xanh.
145
Chu tch Uy ban nhan dan tnh ch ao chnh quyen a phng cac cap, cac nganh thc hien
cac nhiem vu cu the sau:
1. Xac nh vung co dch va lap cac chot kiem dch tam thi, co ngi trc 24/24 gi, co bien
bao, hng dan i lai tranh vung dch; chot kiem dch phai co phng tien va hoa chat sat trung e
x ly moi oi tng ra khoi vung co dch;
2. Khong c van chuyen ln va san pham cua ln ra khoi vung co dch.
3. Ln, san pham cua ln khoe manh c phep van chuyen trong cac trng hp sau:
a) Ln, san pham cua ln thuoc vung b dch uy hiep c phep van chuyen e tieu thu trong
pham vi huyen;
b) Ln, san pham cua ln tai vung em, cua c s chan nuoi c cong nhan an toan dch benh
Tai xanh tai vung b dch uy hiep c van chuyen e tieu thu trong pham vi tnh;
c) Ln, san pham cua ln khong thuoc oi tng quy nh tai iem a, b, khoan 3 ieu nay c
van chuyen ra khoi tnh e tieu thu.
ieu 15. Cong bo het dch
1. Khi co u ieu kien cong bo het dch theo quy nh tai ieu 21 cua Phap lenh Thu y th Chu
tch Uy ban nhan dan cap tnh ra quyet nh cong bo het dch.
2. Ngay sau khi co quyet nh cong bo het dch, cac c s chan nuoi ln tht c phep hoat
ong tr lai bnh thng. Rieng cac c s chan nuoi ln giong thc hien theo quy nh tai khoan 2
ieu 13 cua Quy nh nay.
3. Chu tch Uy ban nhan dan cac tnh lan can ra quyet nh bai bo cong bo vung b dch uy hiep
va vung em tren a ban tnh ngay sau khi co quyet nh cong bo het dch cua tnh co dch.
Chng 4:
TO CHC THC HIEN
1. Cuc Thu y
a) To chc, kiem tra viec thc hien ke hoach giam sat dch benh cac a phng;
b) Hng dan, ch ao cac a phng thc hien; to chc thanh tra, kiem tra tren pham vi toan
quoc ve cong tac phong chong benh Tai xanh;
c) Hng dan cac bien phap ky thuat ve phong chong benh Tai xanh tren c s ban Quy nh nay.
2. Cuc Chan nuoi
a) Hng dan cac a phng thc hien cac quy nh ve quan ly chan nuoi, tieu chuan chuong
trai, tieu chuan con giong, thc an chan nuoi va viec chan nuoi tr lai sau dch.
b) Xay dng tai lieu hng dan va tuyen truyen ngi chan nuoi thc hanh chan nuoi tot.
c) Xay dng cac mo hnh chan nuoi tap trung cong nghiep, ap dung cac bien phap an toan sinh
hoc; pho bien cac mo hnh chan nuoi tot e nhan rong trong pham vi toan quoc.
146
ieu 17. Trach nhiem cua c quan nha nc a phng
1. Cap tnh
a) Uy ban nhan dan tnh
- Thanh lap Ban ch ao phong chong dch Tai xanh cua tnh do Chu tch hoac Pho Chu tch Uy ban
nhan dan tnh lam Trng Ban, lanh ao S Nong nghiep va Phat trien nong thon lam Pho Trng ban.
- Cung co, tang cng cho he thong thu y cap tnh, cap huyen, ac biet la mang li thu y xa,
phng co u ve so lng va am bao chat lng, c trang b ay u phng tien, trang thiet b
e thc thi nhiem vu. Cac a phng cha co mang li thu y xa, phng th can nhanh chong trien
khai thc hien cong van so 1569/TTg-NN ngay 19/11/2007 cua Thu tng Chnh phu ve viec thc
hien che o phu cap cho thu y xa, phng.
- Phe duyet va ch ao to chc thc hien Quy hoach chan nuoi ln, Ke hoach tong the ve
phong chong benh Tai xanh cua tnh, ke hoach hang nam va kiem tra viec thc hien cua cac
cap, nganh thuoc tnh;
- Ch ao cac S, nganh, c quan chuyen mon va cac to chc oan the tai a phng thng
xuyen trien khai cong tac thong tin tuyen truyen phong chong benh Tai xanh;
- Chu tch Uy ban nhan dan tnh cong bo dch, cong bo het dch Tai xanh tren a ban cua tnh
theo quy nh; quyet nh tieu huy ln mac benh hoac uy quyen cho Uy ban nhan dan cap huyen
ra quyet nh tieu huy;
- Hang nam, cap kinh ph cho cong tac phong chong dch benh t quy phong chong thien tai va
d phong ngan sach a phng. b) S Nong nghiep va Phat trien nong thon
- Tham mu cho Uy ban nhan dan tnh trong viec xay dng chng trnh phong chong benh Tai
xanh cua tnh va ke hoach hang nam tren c s Chng trnh quoc gia;
- Ch ao Chi cuc Thu y xac nh vung dch, vung b dch uy hiep, vung co nguy c cao vi benh
Tai xanh;
- To chc thc hien va kiem tra cong tac phong chong benh cua tnh.
c) Chi cuc Thu y
- Trc tiep ch ao, to chc trien khai va kiem tra cong tac phong chong benh Tai xanh tren a
ban tnh;
- Hng dan chuyen mon ve cac bien phap phong chong benh, to chc trien khai giam sat dch
benh Tai xanh.
2. Cap huyen
a) Uy ban nhan dan huyen, quan, th xa, thanh pho trc thuoc tnh (sau ay goi la Uy ban nhan
dan huyen):
- Thanh lap Ban ch ao phong chong benh Tai xanh huyen do Chu tch hoac Pho chu tch Uy
ban nhan dan lam trng ban, Lanh ao Phong Nong nghiep hoac Phong Kinh te, Tram Thu y
huyen lam Pho Trng ban;
- Phoi hp vi Chi cuc Thu y tnh ch ao Tram Thu y huyen, cac Ban, nganh, to chc, ca
147
nhan co lien quan a phng thc hien cac bien phap phong chong benh Tai xanh tren a
ban huyen.
- Huy ong lc lng phuc vu cong tac phong chong benh, ac biet cong tac tiem phong, tieu
huy gia suc mac benh va van chuyen gia suc ra vao a ban.
- Cap ngan sach a phng cho cong tac phong chong dch cua huyen.
b) Phong Nong nghiep, Phong Kinh te, Tram Thu y.
- Trc tiep to chc thc hien cong tac phong chong dch tai huyen;
- Hng dan ky thuat cac bien phap phong chong en tan xa, thon;
- Bao cao kp thi nhu cau ve kinh ph, vat t hoa chat, vac xin, lao ong,... cho Uy ban nhan
dan huyen va Chi cuc Thu y.
3. Cap xa
a) Uy ban nhan dan xa
- Thanh lap Ban ch ao phong chong benh Tai xanh cap xa do Chu tch Uy ban nhan dan lam
Trng ban vi s tham gia cua cap uy ang, chnh quyen, oan the va can bo thu y, nong nghiep;
- Bo tr to chuyen mon e hng dan ky thuat, thng trc va tong hp tnh hnh dch dch benh;
- Ch ao trng thon trc tiep kiem tra, giam sat tnh hnh dch benh; phoi hp vi cac to chc
oan the quan chung (oan Thanh nien, Hoi Phu n, Hoi Nong dan, Hoi Cu chien binh va cac to
chc oan the khac) van ong nhan dan giam sat va thc hien cac bien phap phong chong dch. Moi
thon to chc ky cam ket thc hien 5 khong theo quy nh tai khoan 4 ieu 4 cua Quy nh nay;
- Thanh lap oi xung kch chong dch, gom dan quan t ve, thanh nien, can bo thu y, cong an e
tieu huy gia suc b benh, ve sinh tieu oc kh trung, giam sat ngi ra vao o dch, trc gac tai cac
chot kiem dch ong vat.
b) Nhan vien thu y xa, cong tac vien thu y xa
- Giam sat phat hien benh Tai xanh en tan ho chan nuoi, c s chan nuoi tren a ban xa va
bao cao kp thi cho Uy ban nhan dan xa va Tram Thu y huyen;
- Trc tiep tham gia cong tac phong chong benh, trc tiep tiem phong vac xin;
- Trc tiep tham gia trong giam sat kinh ph ho tr phong chong benh Tai xanh en chu chan nuoi.
sinh, x ly chat thai theo quy nh cua phap luat;
2. Thc hien cac bien phap an toan sinh hoc trong chan nuoi ln va cac bien phap phong chong
benh Tai xanh theo hng dan cua can bo thu y, cua can bo chnh quyen cac cap va nhng ngi
co trach nhiem.
3. Khi thay ln trong gia nh co nhng bieu hien bat thng, b benh th phai bao ngay cho
trng thon, nhan vien thu y xa hoac can bo xa e nhan c s hng dan, ho tr phong chong
dch benh; ong thi chap hanh nghiem cac bien phap phong, chong dch theo Quy nh nay./.
148
1. TAI LIEU THAM KHAO
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2. Tran Ngoc Anh, Nguyen Le Van, To Long Thanh, Trng Van Dung (2004). ap ng mien
dch cua ngan c tiem cac vacxin phong benh Tu huyet trung gia cam, Bao cao khoa hoc
Chan nuoi - Thu y 2004. NXB Nong nghiep.
3. Bo Nong nghiep va PTNT - Ban ch ao quoc gia phong chong cum gia cam. Cam nang
phong chong dch cum gia cam The oc lc cao (H5N2). NXB Nong nghiep.
4. Bo Y te (2005). Ke hoach hanh ong phong chong ai dch cum ngi tai Viet Nam
5. Bo Y te (2006). Phong chong dch cum A (H5N2) lay sang ngi. NXB Y hoc.
6. Bo Y te - Cuc y te D phong (2006). Nien giam thong ke cac benh truyen nhiem (2004
- 2006). NXB Y hoc
7. Tran Minh Chau, Ho nh Chuc, Le Thanh Hai, Pham Sy Lang, ao Hu Thanh, Dng
Cong Thuan (1989). Benh thng thay cho va bien phap phong tr. NXB Nong nghiep.
8. Cong ty thuoc Thu y Trung ng (2004). Cac san pham vacxin Thu y.
9. Cuc Thu y (2007). Bao cao tnh hnh dch benh tren ln cac tnh ong bang song Hong
(DAH). Cuc Thu y.
10. Cuc thu y (2008). Hoi chng roi loan sinh san va ho hap ln (PRRS) - Benh tai xanh. NXB
Nong ngiep.
11. Nguyen Tien Dung, Ho Thu Hng, Ken Inui, Bui Ngha Vng (2004). Nghien cu viec
tiem phong sm vacxin dch ta ln cho ln con. Bao cao khoa hoc chan nuoi - thu y 2004.
NXB Nong nghiep.
12. Nguyen Tien Dung, Ken Inui, Ho Thu Hng (2004). Phan tch di truyen virut dch ta ln
phan lap Viet Nam, Bao cao Khoa hoc chan nuoi Thu y 2004. NXB Nong nghiep
13. Nguyen Tien Dung, Nguyen Van Quang (1993). Th nghiem vacxin Newwcatle chu
nhiet phong benh cho ga nc ta (Tuyen tap cong trnh khoa hoc ky thuat Nong nghiep).
NXB Nong nghiep.
14. ao Trong at, Phan Thanh Phng, Le Ngoc My (1986). Benh ng tieu hoa ln. NXB
Nong nghiep.
15. Pham Ngoc nh, inh Th Kim Xuyen, Nguyen Thu Yen, Phan Th Nga (2007). Hng
dan thc hien mo hnh phong chong chu ong benh viem nao Nhat Ban B khu vc tieu
vung song Me Kong. D an phong chong benh truyen nhiem tieu vung song Me Kong
- Bo Y te.
16. Phan nh o, Trnh Van Thnh (1956). Benh truyen nhiem gia suc (tap I, tap II). NXB
Nong thon.
17. Tran Th Hanh, ang Xuan Bnh (2004). Phan lap, nh typ, la chon chung vi khuan E.Coli
va Cl.perfringens e che tao sinh pham phong benh cho ln con. Bao cao khoa hoc Chan
nuoi - Thu y 2004. NXB Nong ngiep.
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18. Tran Xuan Hanh, Kim Van Phuc, To Th Phan, Nguyen Th Lan Hng, ang Hoang
(2004). Benh xuat huyet do viru tren tho (RDH) - Ket qua bc au nghien cu vacxin vo
hoat phong benh, bao cao khoa hoc Chan nuoi - Thu y 2004. NXB Nong nghiep.
19. Nguyen Ba Hien, Tran Th Minh Tam (2007). Giao trnh vi sinh vat - Benh truyen nhiem
vat nuoi. NXB Ha Noi
20. Nguyen Ba Hien, Nguyen Quoc Doanh, Pham Sy Lang, Nguyen Th Kim Thanh, Chu nh
Ti (2009). Vi sinh vat - Benh truyen nhiem vat nuoi. NXB Giao duc.
21. Pham Sy Lang, Nguyen Trieu Doanh (1987). Benh truyen nhiem trau bo. NXB
Nong nghiep
22. Pham Sy Lang, Pham Ngoc nh, Nguyen Ba Hien, Pham Quang Thai, Van ang Ky
(2009). 8 benh chung quan trong truyen lay gia ngi va ong vat. NXB Ha Noi.
23. Pham Sy Lang, To Long Thanh, Cu Hu Phu, Nguyen Hu Nam (2005, 2009). Mot so benh
mi gia cam va bien phap phong tr. NXB Nong nghiep
24. Pham Sy Lang, To Long Thanh, Pham Quang Thai, o Ngoc Thuy, Hoang ang Huyen
(2010). Ky thuat chan oan, phong tr benh thuy cam. NXB Ha Noi.
25. Pham Sy Lang, Trng Van Dung, Hoang Van Nam, Tran Duy Khanh (2006). Benh truyen
nhiem thng gap ln va bien phap phong tr. NXB Nong nghiep
26. Pham Sy Lang, Van ang Ky (2008). Ho chng roi loan sinh san va ho hap (PRRS) va benh
lien cau khuan ln. NXB Nong nghiep.
27. Pham van Luc, Nguyen Th Tuyet Minh, ang Th Tam (2004). Nghien cu xac nh hieu
qua phong benh Gumboro bang vacxin vo hoat nhu au cho ga tha vn giai oan 1 - 56
ngay tuoi, Bao cao khoa hoc Chan nuoi - Thu y 2004. NXB Nong nghiep.
28. Pham Quang Thai, Tran Xuan Hanh, To Th Phan, Nguyen Thien Thu, Pham Hao Quang,
Trng Van Dung (2007). o dai bao quan va mien dch cua vacxin tu huyet trung nhu dau
chung P52, Tap ch KHKT Thu y.
29. Pham Quang Thai (2008). Nghien cu che tao vacxin nhu dau tu huyet trung trau bo t
chung P52. Luan an Tien s Nong Nghiep.
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phong benh tu huyet trung trau bo san xuat theo cong nghe len men cai tien, Tap ch KHKT
thu y,opgraphy VIII, so 4/2006.
31. To Long Thanh, Le Tran Phan, Trng Th Hong Hoa, Trng Van Dung (2004) San xuat
va s dung khang the cong hp e khang IgG cua tho gan men Peroydae, Bao cao khoa hoc
Chan nuoi - Thu y 2004. NXB Nong nghiep
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bc au san xuat khang the n dong khang chung virus Newcastle cng oc, Bao cao
khoa hoc Chan nuoi - Thu y 2004. NXB Nong nghiep.
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khuan Enterotoxigenic Escherichia coli gay benh tieu chay cho ln con mot so tnh mien
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virus vaccines and Immunity, Mosby Pulishing House - New York, London.
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B.V.Australia - London.
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Reproductive and Respiratory Syndrome Virus, Virus Research 122 91 - 2) i 175 - 183
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A Tyfical, PRRS in China and Molecular Dissection of the Unique Hallmark, PLOSive ONE (6).
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and diagnosis of certain animal diseases, Mexico - United states commission for prevention of
FMD. Mexico.
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Swine (2005). Jova Starte University Press, Iowa, USA.
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OIE - Paris.
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ACIAR Canberra - Australia.
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J.Ettinger, Edward C.Felman (1996). Texbook of Veterinary Medicine = Diseases of the dogs
and the cat. W.B Sauder Company, Philadelphia - London Sydney.
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State Press - Blackwell Publishing Company.
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International PRRS Symposium 2006.
151
NHA XUAT BAN VAN HOA - THONG TIN
43 Lo uc - Ha Noi
T: 04 3971 2448
VACXIN THU Y VA HNG DAN S DUNG
Chu trach nhiem xuat ban

LE TIEN DUNG
Chu trach nhiem ban thao
VU THANH VIET
Bien tap : Lai Giang

Trnh bay - Ba : Vu Hng Mai
Noi dung : Pham Sy Lang
Nguyen Ba Hien
Phung Quoc Quang
In tai: Cong ty TNHH phat trien Thng hieu Quang cao INNET
So lng: 1.500 cuon. khuon kho: 19 x 27 cm
Quyet nh XB so: 1273/VHTT
In xong va nop lu chieu thang 12 / 2012
152

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BO NONG NGHIEP VA PHAT TRIEN NONG THON

TRUNG TAM KHUYEN NONG QUOC GIA

PGS.TS. Pham Sy Lang

TRUNG TAM KHUYEN NONG QUOC GIA

Chng 1: NH NGHA VA PHAN LOAI VACXIN

I. NGUYEN TAC S DUNG VACXIN THU Y

I. MOT SO QUY NH CHUNG VE LCH TIEM PHONG

2. Lch s dung vacxin phong benh cho ln

LCH TIEM PHONG VACXIN CHO LN HAU B

LCH TIEM PHONG VACXIN CHO LN NAI

LCH TIEM PHONG VACXIN CHO AN GA GIONG THT

LCH TIEM PHONG VACXIN CHO AN GA GIONG TRNG

LCH TIEM PHONG VACXIN CHO AN GA THNG PHAM TRNG

4. Lch s dung vacxin phong benh cho vt - ngan

5. Lch s dung vacxin phong benh cho cho - meo

I. VACXIN DUNG CHO TRAU BO

- Virus c nuoi cay tren moi trng te bao BHK

* MDA: khang the me truyen sang con.

Hng dan s dung:

* MDA: khang the me truyen sang con.

BO NONG NGHIEP CONG HOA XA HOI CHU NGHA VIET NAM

BO TRNG BO NONG NGHIEP VA PHAT TRIEN NONG THON

Can c Phap lenh Thu y ban hanh ngay 29/4/2004;

ieu 4. Tuyen truyen benh LMLM va cach phong chong

BO TRNG BO NONG NGHIEP VA PHAT TRIEN NONG THON

Can c Phap lenh Thu y ngay 29 thang 4 nam 2004;

ieu 5. Tuyen truyen phong, chong benh dch ta ln

Ni nhan: KT. BO TRNG

ieu 1. Pham vi ieu chnh

ieu 5. Tuyen truyen ve phong, chong benh Niu-cat-xn

ieu 11. Khai bao va x ly o dch au tien nghi mac benh

ieu 17. Trach nhiem cua c quan nha nc Trung ng

Ni nhan: KT. BO TRNG

BO TRNG BO NONG NGHIEP VA PHAT TRIEN NONG THON

Can c Phap lenh Thu y ban hanh ngay 29/4/2004;

Ni nhan: KT. BO TRNG

ieu 1. Pham v ieu chnh va oi tng ap dung

I. Tai lieu trong nc.

VACXIN THU Y VA HNG DAN S DUNG

Chu trach nhiem xuat ban

Bien tap : Lai Giang

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