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Existe controversia respecto a la interacción del
ácido ortofosfórico con las MMPs
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1. Osorio R, Yamauti M, Osorio E, Ruiz-Requena ME, Pashley D, Tay F, Toledano M. Effect of dentin
etching and chlorhexidine application on metalloproteinase-mediated collagen degradation. Eur
J Oral Sci 2011; 119: 79–85.
2. Moon P, Weaver J, Brooks C. Review of Matrix Metalloproteinases’ Effect on the Hybrid Dentin
Bond Layer Stability and Chlorhexidine Clinical Use to Prevent Bond Failure. The Open Dentistry
Journal, 2010, 4, 147-152.
3. Koshiro K, Inoue S, Tanaka T, et al. In vivo degradation of resin dentin bonds produced by a self-
etch vs. a total-etch adhesive system. Eur J Oral Sci 2004; 112(4): 368-75.
4. Carrilho MRO, Geraldeli S, Tay F, et al. In vivo preservation of the hybrid
layer by chlorhexidine. J Dent Res 2007; 86(6): 529-33.
5. Saffarpour A, Valizadeh S, Amini A, Kharazifard MJ, Rohaninasab M.
Effect of matrix metalloproteinase inhibitors on microtensile bond dentista
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