7/4/23, 11:02 Bumetanida Información avanzada para pacientes - Drugs.

com

Bumetanida (oral)
Revisado médicamente por Drugs.com. Última actualización el 1 de enero de 2023.

Vía oral(Tableta)

La bumetanida es un diurético potente que, si se administra en cantidades excesivas, puede

provocar una diuresis profunda con agotamiento de agua y electrolitos. Por lo tanto, se requiere
una cuidadosa supervisión médica y la dosis y el programa de dosificación deben ajustarse a las
necesidades individuales del paciente.

Nombre(s) de marca de uso común

En los EE.UU

Bumex

Formas de dosificación disponibles:

Tableta

Clase Terapéutica: Agente Cardiovascular

Clase Farmacológica: Diurético, Asa

Usos de la bumetanida
La bumetanida pertenece a un grupo de medicamentos llamados diuréticos de asa o "píldoras de agua".
La bumetanida se administra para ayudar a tratar la retención de líquidos (edema) y la hinchazón
causada por insuficiencia cardíaca congestiva, enfermedad hepática, enfermedad renal u otras
afecciones médicas. Actúa actuando sobre los riñones para aumentar el flujo de orina.

La bumetanida está disponible solo con receta médica.

Antes de usar bumetanida

Al decidir usar un medicamento, los riesgos de tomar el medicamento deben sopesarse frente al bien
que hará. Esta es una decisión que tomarán usted y su médico. Para la bumetanida, se debe considerar
lo siguiente:

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alergias
Tell your doctor if you have ever had any unusual or allergic reaction to bumetanide or any other
medicines. Also tell your health care professional if you have any other types of allergies, such as to
foods, dyes, preservatives, or animals. For non-prescription products, read the label or package
ingredients carefully.

Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of bumetanide in
the pediatric population. Safety and efficacy have not been established .

Geriatric
Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would
limit the usefulness of bumetanide in the elderly. However, elderly patients are more likely to have age-
related liver, kidney, or heart problems, which may require an adjustment of dosage in patients receiving
bumetanide .

Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during
breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while
breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines
may be used together even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. When you are taking bumetanide, it is
especially important that your healthcare professional know if you are taking any of the medicines listed
below. The following interactions have been selected on the basis of their potential significance and are
not necessarily all-inclusive.

Using bumetanide with any of the following medicines is not recommended. Your doctor may decide not
to treat you with this medication or change some of the other medicines you take.

Desmopressin

Using bumetanide with any of the following medicines is usually not recommended, but may be required
in some cases. If both medicines are prescribed together, your doctor may change the dose or how often
you use one or both of the medicines.

Aceclofenac Acemetacin

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Albuterol Floctafenine

Amtolmetin Guacil Flufenamic Acid

Arsenic Trioxide Flurbiprofen

Aspirin Foscarnet

Bepridil Ibuprofen

Bromfenac Indomethacin

Bufexamac Ketanserin

Celecoxib Ketoprofen

Choline Salicylate Ketorolac

Clonixin Levomethadyl

Dexibuprofen Lithium

Dexketoprofen Lornoxicam

Diclofenac Loxoprofen

Diflunisal Lumiracoxib

Digitoxin Meclofenamate

Dipyrone Mefenamic Acid

Dofetilide Meloxicam

Droperidol Metolazone

Droxicam Morniflumate

Etodolac Nabumetone

Etofenamate Naproxen

Etoricoxib Nepafenac

Felbinac Niflumic Acid

Fenoprofen Nimesulide

Fepradinol Nimesulide Beta Cyclodextrin

Feprazone Oxaprozin

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Oxyphenbutazone Salsalate

Parecoxib Sodium Salicylate

Phenylbutazone Sotalol

Piketoprofen Sulindac

Piroxicam Tenoxicam

Proglumetacin Tiaprofenic Acid

Propyphenazone Tolfenamic Acid

Proquazone Tolmetin

Rofecoxib Valdecoxib

Salicylic Acid

Using bumetanide with any of the following medicines may cause an increased risk of certain side
effects, but using both drugs may be the best treatment for you. If both medicines are prescribed
together, your doctor may change the dose or how often you use one or both of the medicines.

Benazepril Licorice

Captopril Lisinopril

Cilazapril Moexipril

Dibekacin Neomycin

Enalapril Perindopril

Enalaprilat Quinapril

Fosinopril Ramipril

Germanium Spirapril

Ginseng Streptomycin

Gossypol Trandolapril

Kanamycin Zofenopril

Interactions with food/tobacco/alcohol

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Certain medicines should not be used at or around the time of eating food or eating certain types of food
since interactions may occur. Using alcohol or tobacco with certain medicines may also cause
interactions to occur. Discuss with your healthcare professional the use of your medicine with food,
alcohol, or tobacco.

Other medical problems

The presence of other medical problems may affect the use of bumetanide. Make sure you tell your
doctor if you have any other medical problems, especially:

Anuria (not able to form urine) or

Liver disease, severe (e.g., hepatic coma)—Should not use in patients with these conditions .

Dehydration or

Gout or

Hyperuricemia (high uric acid in the blood) or

Hypocalcemia (low calcium in the blood) or

Hypokalemia (low potassium in the blood) or

Hypomagnesemia (low magnesium in the blood) or

Hypovolemia (low blood volume) or

Thrombocytopenia (low platelets in the blood)—Use with caution. Bumetanide may make these
conditions worse .

Diabetes—Bumetanide may increase the amount of sugar in the blood .

Kidney disease, severe—Use with caution. The effects may be increased because of slower
removal of the medicine from the body .

Proper use of bumetanide

Dosing
The dose of bumetanide will be different for different patients. Follow your doctor's orders or the
directions on the label. The following information includes only the average doses of bumetanide. If your
dose is different, do not change it unless your doctor tells you to do so.

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The amount of medicine that you take depends on the strength of the medicine. Also, the number of
doses you take each day, the time allowed between doses, and the length of time you take the medicine
depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets):

For edema:

Adults—0.5 to 2 milligrams (mg) once a day. Your doctor may adjust your dose if needed.

Children—Use and dose must be determined by your doctor .

Missed dose
If you miss a dose of bumetanide, take it as soon as possible. However, if it is almost time for your next
dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Bumetanide dosage information

Precautions while using bumetanide

It is very important that your doctor check your progress at regular visits to make sure bumetanide is
working properly. Blood tests may be needed to check for unwanted effects .

Bumetanide may cause you to lose more potassium from your body than normal. Your doctor will
monitor the potassium in your blood while you are taking bumetanide. To prevent the loss of too much
water and potassium, tell your doctor if you become sick with severe or continuing nausea, vomiting, or
diarrhea. Check with your doctor right away if you have one or more of these symptoms: dry mouth;
increased thirst; muscle cramps; or nausea or vomiting .

Bumetanide can lower the number of platelets in your blood. Platelets are necessary for proper blood
clotting. Check with your doctor immediately if you notice any unusual bleeding or bruising; black, tarry
stools; blood in the urine or stools; or pinpoint red spots on your skin .

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Bumetanide may cause changes in your blood sugar levels. If you notice a change in the results of your
blood or urine sugar tests, or if you have any questions, check with your doctor .

Bumetanide side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these
side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Abdominal pain

blurred vision

confusion

decreased urine output

dizziness

drowsiness

dry mouth

fast or irregular heartbeat

flushed, dry skin

fruit-like breath odor

headache

increased hunger

increased thirst

increased urination

irritability

joint pain, stiffness, or swelling

loss of appetite

loss of mental alertness

lower back, side, or stomach pain

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mood or mental changes

muscle pain or cramps

nausea or vomiting

numbness or tingling in the hands, feet, or lips

shortness of breath

sweating

swelling of face, hands, feet, ankles, or lower legs

troubled breathing

unexplained weight loss

unusual tiredness or weakness

weak pulse

Rare

Agitation

back pain

black, tarry stools

bleeding gums

blood in the urine or stools

chest pain

convulsions (seizures)

deep or fast breathing with dizziness

dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly

fever

hallucinations

hives

increase in heart rate

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increased blood pressure

numbness of feet, hands, and around the mouth

pinpoint red spots on the skin

rapid breathing

stiff neck

sunken eyes

trembling, jerking of hands

unusual bleeding or bruising

weight gain

wrinkled skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Difficulty breathing

pain in chest, groin, or legs, especially the calves

severe, sudden headache

slurred speech

sudden loss of coordination

sudden, severe weakness or numbness in the arm or leg

sudden, unexplained shortness of breath

unusual drowsiness, dullness, or feeling of sluggishness

vision changes

Some side effects may occur that usually do not need medical attention. These side effects may go
away during treatment as your body adjusts to the medicine. Also, your health care professional may be
able to tell you about ways to prevent or reduce some of these side effects. Check with your health care
professional if any of the following side effects continue or are bothersome or if you have any questions
about them:

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Rare

Decreased interest in sexual intercourse

diarrhea

difficulty with moving

ear discomfort

feeling of constant movement of self or surroundings

inability to have or keep an erection

itching skin

loss in sexual ability, desire, drive, or performance

muscle or bone pain

muscle stiffness

nipple tenderness

pain, swelling, or redness in joints

rash

sensation of spinning

shorter than usual time to ejaculation of semen

trouble with hearing

upset stomach

Other side effects not listed may also occur in some patients. If you notice any other effects, check with
your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-
FDA-1088.

Bumetanide side effects (more detail)

Frequently asked questions

What are the equivalent dosages of bumetanide, furosemide & torsemide?

Más información
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Siempre consulte a su proveedor de atención médica para asegurarse de que la información que se
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