medicamento observacione

A 12647.2111 12849.1866 13038.12 12104.744 11824.4054

B 12227.7825 13133.2618 12333.2961 12835.0245 12791.1047
C 13746.2236 12049.9501 12453.3378 12102.4248 12534.8971
D 12312.7607 11666.2871 12893.8398 12907.0044 11555.031
E 12231.9552 11941.1094 12797.2368 12853.862 12859.9982

Un laboratorio de análisis fisicoquímico comparó la cantidad de ampicilina contenida en cápsulas de 5 medicam

siguientes resultados.

Plantear las hipótesis nula y alternativa para determinar si hay o no diferencias significativas en la cantidad de a
Determinar a partir de intervalos de confianza al 95% si hay diferencias o no entre los medicamentos.

PRUEBAS DE HIPOTESIS.
Hipótesis nula:
 observaciones
12992.4296 13323.1365 12536.604 13165.5165 11870.0713 12616.6937 11117.0931
12677.7597 11368.0557 12564.4288 12770.8822 12868.391 13015.851 12376.6401
11983.821 12138.8571 12143.3881 13201.3931 12748.6534 12646.7656 12336.5097
12537.7222 13065.2857 12212.0362 11536.2332 12424.0168 11906.3114 11794.994
12271.3877 12023.9545 12110.7184 12734.4141 12177.4599 12558.0698 11664.8366

contenida en cápsulas de 5 medicamentos comerciales diferentes, encontrandose los

ncias significativas en la cantidad de ampicilina en los 5 medicamentos.

no entre los medicamentos.

UEBAS DE HIPOTESIS.
 𝑡_(𝛼/2,𝑛−1) LIMITE
Media S Raiz n t Tablas 𝑠/√𝑛 SUPERIOS
𝑠/√𝑛
(LS)
12507.101 655.908632 189.3445 490.9879 12998.0888
12580.2065 470.024746 135.6845 351.8424 12932.0489
12507.1851 525.923155 3.46 2.59 151.8209 393.6858 12900.8709
12234.2935 546.449608 157.7464 409.0511 12643.3446
12352.0836 399.442478 115.3091 299.0072 12651.0908

construir intervalos al 95% de confianza

a= 0.05 0.025
 LIMITE
MEDIA A B C
INFERIOS (LI)

12507.101 12016.1131 LS 12998.0888 12932.0489 12900.8709

12580.2065 12228.3641 X 12507.101 12580.2065 12507.1851
12507.1851 12113.4994 LI 12016.1131 12228.3641 12113.4994
12234.2935 11825.2425
12352.0836 12053.0763 Chart Title
13200

e confianza 13000

12800

12600

12400

12200

12000
A B C D

LI
 D E

12643.3446 12651.0908
12234.2935 12352.0836
11825.2425 12053.0763

Chart Title

C D E

LI
 medicamento observacione
A 12647.2111 12849.1866 13038.12 12104.744 11824.4054
B 12227.7825 13133.2618 12333.2961 12835.0245 12791.1047
C 13746.2236 12049.9501 12453.3378 12102.4248 12534.8971
D 12312.7607 11666.2871 12893.8398 12907.0044 11555.031
E 12231.9552 11941.1094 12797.2368 12853.862 12859.9982

Análisis de varianza de un factor

RESUMEN
Grupos Cuenta Suma Promedio Varianza
12647.2111 4 50518.7219 12629.6805 555604.74
12849.1866 4 48790.6085 12197.6521 415114.72
13038.12 4 50477.7106 12619.4276 72125.0615
12104.744 4 50698.3157 12674.5789 146422.373
11824.4054 4 49741.0311 12435.2578 363919.564
12992.4296 4 49470.6905 12367.6726 93894.5557
13323.1365 4 48596.153 12149.0383 488397.566
12536.604 4 49030.5715 12257.6429 43612.827
13165.5165 4 50242.9226 12560.7306 511457.671
11870.0713 4 50218.5211 12554.6303 98469.3984
12616.6937 4 50126.9977 12531.7494 213149.501
11117.0931 4 48172.9804 12043.2451 133992.638

ANÁLISIS DE VARIANZA
Origen de las variaciones
Suma de cuadrados
Grados dePromedio
libertad de los cuadradosF Probabilidad
Entre grupos 1972283.37 11 179298.488 0.68605602 0.7424272
Dentro de los 9408481.84 36 261346.718

Total 11380765.2 47
 observaciones
12992.4296 13323.1365 12536.604 13165.5165 11870.0713 12616.6937 11117.0931
12677.7597 11368.0557 12564.4288 12770.8822 12868.391 13015.851 12376.6401
11983.821 12138.8571 12143.3881 13201.3931 12748.6534 12646.7656 12336.5097
12537.7222 13065.2857 12212.0362 11536.2332 12424.0168 11906.3114 11794.994
12271.3877 12023.9545 12110.7184 12734.4141 12177.4599 12558.0698 11664.8366

Valor crítico para F

2.06660848
medicamento observacione
A 12647.2111 12849.1866 13038.12 12104.744 11824.4054
B 12227.7825 13133.2618 12333.2961 12835.0245 12791.1047
C 13746.2236 12049.9501 12453.3378 12102.4248 12534.8971
D 12312.7607 11666.2871 12893.8398 12907.0044 11555.031
E 12231.9552 11941.1094 12797.2368 12853.862 12859.9982

F= probabilida GLE,
GDD
F=0.025,4,55
95% confianza
a=0.05 (probabilidad)
 observaciones
12992.4296 13323.1365 12536.604 13165.5165 11870.0713 12616.6937 11117.0931
12677.7597 11368.0557 12564.4288 12770.8822 12868.391 13015.851 12376.6401
11983.821 12138.8571 12143.3881 13201.3931 12748.6534 12646.7656 12336.5097
12537.7222 13065.2857 12212.0362 11536.2332 12424.0168 11906.3114 11794.994
12271.3877 12023.9545 12110.7184 12734.4141 12177.4599 12558.0698 11664.8366
 (𝑌𝑖^2)/𝑛𝑖 𝑆𝐶𝐸=∑8_(𝑖=1)▒
(𝑌..^2)/𝑁 〖 (𝑌𝑖^2)/𝑛^2 −(𝑌 〖
Yi Yi2 Y…2 ni N

150085.212 22525570755
150962.478 22789669781
150086.221 22525873884 5.5677E+11 12 60 9280449079 9279505333
146811.522 21553623115
148225.003 21970651417
746170.4363 111365388951
 ∑24_(𝑖=1)^𝑎▒∑24_(𝑗=1)^𝑛𝑖▒
∑8_(𝑖=1)▒ 〖 (𝑌𝑖^2)/𝑛^2 −(𝑌 〖 .. 〗 ^2)/𝑁 〗 〖𝑌〖𝑖𝑗〗 ^2 〗
(𝑌..^2)/𝑁
𝑆𝐶𝑇=∑_(𝑖=1)^𝑎▒∑_(𝑗=1)^𝑛𝑖
▒ 〖𝑌〖𝑖𝑗〗 ^2 〗 -(𝑌..^2)/𝑁

943746.028642654 9295693936 9279505333 16188602.333025

𝑆𝐶𝐷=𝑆𝐶𝑇−𝑆𝐶𝐸 FUENTE DE VARIACION (FV)

ENTRE TRATAMIENTOS
ERROR (DENTYRO DE LOS TRATAMIENTOS)
15244856.3043823 TOTAL
SUMA DE CUADRADOS (SC O SS) GRADOS LIBERTAD (GL O DF) CUADRADO MEDIO (CM O MS)

943746.028642654 4 235936.507160664
15244856.3043823 55 277179.205534224
16188602.333025 59
F ONSERVADO (Fo) F CRITICA (Fc) CRITERIO DE ACEPTACION

4289.75467564843 2.54
0.85120565486119