Documentos de Académico
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METOMETOMEOT
METOMETOMEOT
Resumen
La observación de que «lo mismo no sirve para todos» en la prevención y el
tratamiento de las enfermedades cardiovasculares, entre otras, ha propulsado
el concepto de medicina de precisión. Su objetivo es proporcionar las mejores
intervenciones basadas en la información adicional que aporta el genoma. El
genoma humano se compone de miles de millones de pares de bases que
contienen un código que controla cómo se expresan los genes. Este código
depende de reguladores no estáticos que rodean el ADN y constituyen el
epigenoma. Además, los factores ambientales también desempeñan un papel
importante en esta compleja regulación. Se presenta una perspectiva general
sobre los conceptos básicos de la biología molecular relacionados con la
genética y la epigenética y un glosario de términos clave, se revisan varios
ejemplos de polimorfismos y escalas de riesgo genético relacionadas con el
riesgo cardiovascular, y se proporciona una visión general de los principales
reguladores epigenéticos, como la metilación del ADN, las proteínas de unión a
metilcitosina-fosfato-guanina, las modificaciones de histonas, otras
regulaciones de histonas, los efectos de los microARN y otros reguladores
emergentes. Otro desafío es entender cómo los factores ambientales (dieta,
ejercicio, tabaco, etc.) pueden alterar el epigenoma y resultar en fenotipos
saludables o no. Se comentan algunas interacciones entre gen y ambiente y se
proporciona una visión metodológica general.
TEMA: La protección de la biodiversidad en el derecho ambiental
Mexicano: un análisis de la legislación desde el enfoque de especies
amenazadas y su hábitat crítico
AUTOR: Juan CarlosOlivo Escudero*
Resumen
La urolitiasis se ha convertido en una enfermedad crónica que ha tenido un
gran impacto en la calidad de vida y en la situación laboral de quien la padece;
su tasa de prevalencia y recurrencia es cada vez mayor, lo que genera un gran
impacto socioeconómico en cualquier país al afectar el sistema de salud. Se
han identificado numerosos factores inherentes a la biología humana y algunas
variables sociodemográficas, que favorecen el desarrollo de cálculos renales;
por lo cual, en esta revisión se describen los principales factores que influyen
en la formación de urolitiasis, permitiendo intervenir oportunamente sobre
algunos de ellos.
TEMA: Numerical study of fog formation around ambient air vaporizers
Abstract
Ambient air vaporizers (AAVs) are used to re-gasify cryogenic industrial gases
for distribution and use. Although AAVs have low carbon footprint, fog formation
around the ambient air vaporizers is a common problem, thus often leading to
reduced visibility. Moreover, since AAVs exchange the heat from the
surrounding air, the efficiency of the process is also at stake due to possible
recycling of exiting air. Thus, simulating fog formation, dispersion and
dissipation around AAVs is of critical importance. So far most of the studies for
AAV consider fog in single phase framework, which are incapable of simulating
the dispersion and dissipation of fog accurately. In this study, multiphase model
of fog formation and dissipation has been developed considering
the thermodynamics and heat transfer effects. The models have been validated
using available wind tunnel data for a velocity and temperature field around a
sample obstacle. A parametric study has been also presented to demonstrate
the effect of wind velocity, AAV inlet air velocity and number of AAV units on the
ambient conditions. The study provides an in-depth insight of the process and
presents an analysis of operating conditions suitable for AAVs.
Abstract
Ambient vibration testing is a convenient and cost-effective alternative to impact
testing as it doesn’t require artificial excitation devices and traffic control. The
lack of input force measurement in ambient vibration testing, however, does
impede the identification of structural scaling factors, which are extremely
important for Frequency Response Functions (FRFs) estimation and flexibility
identification. A moving mass technique of identifying structural scaling factors
from output-only data is proposed in this article. By this method, a vehicle
passing over a bridge is regarded as a moving mass with spatial and time
variation on the structure, inducing a vehicle-bridge system with time-varying
modal properties. Theoretical derivation will be performed to identify scaling
factors from the measured vibration responses of the bridge with and without
the moving vehicle. Magnitudes of FRFs and the structural flexibility matrix can
be obtained once the scaling factors are identified. The proposed method
delivers comparable results to impact testing but is considerably more
convenient. Numerical and experimental examples are studied to verify the
effectiveness of proposed method. The effects of vehicle speed, mass value
and measurement noise are also investigated.
TEMA: Experimental study of the dew formation effect on the performance
of photovoltaic modules
Abstract
The performance of photovoltaic modules is related to climatic conditions. The
aim of this study was to investigate the effect of dew formation on the
performance parameters of two solar cell types including mono-crystalline
silicon (mc-Si) and polycrystalline silicon (pc-Si) in the laboratory scale. The
experiments were performed by using an environmental chamber equipped with
a solar simulator based on LED light. The dew formation on the panel surface
was conducted at three levels of 45, 60 and 75% and ambient temperature of
25 °C. Based on the psychometric chart, the dew points temperature are 12.5,
8.5 and 4.5 °C lower than 25 °C corresponding to the relative humidity levels of
45, 60 and 75%, respectively. The percentages of the covering of dew on the
module surface were estimated to be 45.19, 63.50 and 83.62% at relative
humidity levels of 45, 60 and 75%, respectively. The performance parameters
including the open-circuit voltage, short-circuit current, maximum power,
maximum voltage, and maximum current were determined from the I V and
P V characteristics curves for the humid air and dew formation conditions.
Moreover, the output electrical power and the variations in relative efficiency
were calculated. The results showed that the presence of dew on the surface of
solar modules enhanced the photovoltaic performance parameters compared to
humid air. For the mc-Si solar cell, at the dew formation condition with
considering corrected the effect of temperature, the relative efficiency increased
about 2.83, 3.13 and 4.06% the corresponding to the humid air conditions, while
the values for pc-Si solar cell were 1.45, 3.26 and 4.39%. All photovoltaic
performance parameters were decreased linearly by increasing the amount of
dew covering on the module's surface.
TEMA: Modifications of exposure to ambient particulate matter: Tackling
bias in using ambient concentration as surrogate with particle infiltration
factor and ambient exposure factor
AUTOR: ShanshanShia
AÑO DE PUBLICACION: 2017
SITIO DE PUBLICACION: Environmental Pollution
TEMA:
The influence of freezing and ambient temperature on the adhesion
strength of ice