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Lesions in the Colon:
ë mhortening of villi with loss of the
epithelium to complete loss of intestinal
architecture.
ë Neutrophilic reaction in the lamina
propria
ë Thrombi may be seen in blood vessels
in this region.
ë Hemorrhage and fibrin strands are
usually seen.
m      m  m

Ô TIENT INFO

Name: ccount of Greece


mpecie: Equine
mex: Male (stallion)
Weight: 475kg
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C mE: malmonella sp.


CLINIC L mIGNm:
fever cardiovascular function compromised
depression due to dehydration (10%)
colic-type signs and endotoxemia
watery diarrhea tachycardia
RR & HR elevated injected mucous membranes
leukopenia cold extremities
hypoproteinemia
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I GNOmIm
Clinical Findings: malmonella Culture from feces
ë Obtain at the onset of depression and fever
ë Minimum of 5 cultures, 10-30g feces Enrichment technique
ë Tetrathionate brilliant agar broth (allow growth) and selenite broth (inhibit
growth)
Metabolic acidosis
CBC: Hemoconcentration
Leukopenia
merum Chemistry: Hypokalemia
Hypocalcemia
merum albumin <20g/L or 2g/dl
m      m  m

MEIC TIONm
1. Ôenicillin ² Gentamicin combination 7. KCl 20-40 mmol/L (mEq/L)
2. TMÔ-m 8. Na Bicarbonate
3. Flunixin meglumine 9. Hypertonic fluid
4. MmO 10. Ôlasma transfusion
5. Ôlasma therapy 11. malmonella antisera
6. Fluid therapy 12. Bismuth malicylate
13. Mineral oil via NGT
           

  

Catheter Ôlacement
ë NOTE: lways check for thrombophlebitis
due to endotoxemia, irritation due to
infusion of medications and bacterial
colonization of the catheter tip.
  

ntibiotic therapy:
YEm, Why?
ë To kill the bacteria
ë To prevent the likelihood of septicemia
ë To prevent seeding of other tissues with the
bacteria
m
mm
re the treatment/management procedures prescribed
insufficient, inappropriate, excessive, etc? Explain your answer.

mome of the treatment/management procedures are


inappropriate and excessive.

(will be explained/elaborated as we go along the discussion)


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Ôroponents of antibiotic usage recommend a member of
the fluoroquinolone class of drug in non food animal species and
human patients.
Treatment of the sytemic form of salmonellosis includes
nursing care and appropriate antimicrobial therapy as determined
by retrospectively acquired susceptibility data. mince salmonellae
survive in the phagocytic cell, the antimicrobial drug should be
one that penetrates the cell. Examples of those that distribute in
this manner include ampicillin, enrofloxacin, trimethoprim-
sulfonamides, and chloramphenicol.
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- ose: 60ml/dose

- osage form: paste

- Route: ÔO

- uration: bid for 2days

- mpecific brand: Corrective Mixture (Beescham)


escription treatment dose osage Brand price uration Total
form of Tx
antibiotic therapy TMÔ-m 22mg/kg Inj, meptotryl 1-2weeks,
100ml upto 4wks
bottle
Nm I FluMeg 1.1mg/kg Inj, Banamine Ô3270.00 sid, 5d Ô3270.00
100ml
FLIm: LRm IV Euro-Med Ô57.00 Ô3534.00
addresses infusion +
dehydration; ,
hypokalemia & 1000ml
hypocalcemia;
metabolic acidosis
addresses Ôlasma IV
hypoproteinemia solution
addresses malmonella IVmol·n, B Horse Ô5,128.0
endotoxemia antisera 100ml Bld efibrin 0
anti-diarrheal; Bismuth 60ml/ paste Corective bid-tid, til Ô348.00
GIT protectant salicylate dose Mixture diarrhea
(Beescham) disappears
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 The cost of the treatment may appear expensive but is still practical
because the chosen drug components of the medications are
NECEmm RY to alleviate the infection of the animal.

 Take in consideration that treating diseases in large animals, like


horses, may require large amount of money.
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 This disease is management related.

 How do we deal with it:


ë Transient animals should not be comingled with permanent
residents
ë Control movement of people and equipment
ë Keep the stable clean and sanitized
ë Once an outbreak occur, cleaning and disinfecting protocols
should be reviewed and strictly enforced.
     m



 How do we deal with it:


ë Cleanliness of the surroundings.
ë Management protocols such as vaccination schedule, diet and
breeding schedule should be manipulated such that it would
lessen the stress experienced by the animal.
ë uring antimicrobial therapy, always consider drug resistance,
safety, contraindications and side effects.
 
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