Está en la página 1de 23

SUBJECT:

HERBAL MEDICINE AND PHARMACEUTICAL MEDICINE IN THE TREATMENT OF


ANIMALS CANCER

DISCIPLINE: PLANT BIOLOGY

PROFESSOR :
STUDENT
The first thing to note is that many pharmaceutical drugs were born out of
herbal medicine, and presently over twenty five percent of all pharmaceutical drugs
are still made from herbs. However, the majority of drugs are founded from the
practice of Alchemy, and derived from chemicals.
Modern drugs have only emerged within the last hundred years, as man
developed the ability to probe into the chemical make up of matter and to isolate
and synthesize chemical compounds.
Herbalism is the study of botany and use of plants intended
for medicinal purposes or for supplementing a diet. Herbal medicine is used to treat many
conditions, such as allergies, asthma, eczema, premenstrual syndrome, rheumatoid
arthritis, fibromyalgia, migraine, chronic fatigue, irritable bowel syndrome, and cancer,
among others.
Ginkgo (Ginkgo biloba) has been used in traditional medicine to treat
circulatory disorders and enhance memory. Laboratory studies have shown that
ginkgo improves blood circulation by dilating blood vessels and reducing the
stickiness of blood platelets.
Kava kava (Piper methysticum)
is said to elevate mood, enhance wellbeing
and contentment, and produce a feeling of
relaxation.
St. John's
wort (Hypericum perforatum) is
well known for its antidepressant
effects. In general, most studies
have shown that St. John's wort
may be an effective treatment for
mild-to-moderate depression, and
has fewer side effects than most
other prescription antidepressants.
Valerian (Valeriana officinalis) is a popular alternative to commonly
prescribed medications for sleep problems because it is considered to be both safe
and gentle.
Echinacea preparations (from Echinacea purpurea and
other Echinacea species) may improve the body's natural immunity.
Pharmaceutical medicine is a medical discipline concerned with the
discovery, evaluation, registration, monitoring and clinical aspects of
pharmaceutical development.
A pharmaceutical drug is a drug used to diagnose, cure, treat,
or prevent disease. Pharmaceutical or a drug is classified on the basis of their
origin.
Drug from natural origin: Herbal or plant or mineral
origin, some drug substances are of marine origin.
Drug from chemical as well as natural origin: Derived from partial
herbal and partial chemical synthesis, example steroidal drugs
Drug derived from microbial origin: Antibiotics
Drug derived by biotechnology genetic-engineering, hybridoma
technique for example, drug derived from radioactive substances.
POSSIBLE HERB AND DRUG INTERACTIONS
It’s important to be aware of any interactions between herbs and pharmaceuticals.
Here are some common herb/drugs interactions:
Conventional cancer treatments using chemotherapy and radiation may be
effective in getting rid of cancerous tumors, but such treatments can sometimes be harsh
and tough on your dog. Such treatments can greatly compromise the proper functioning
of the immune system.
Herbs can be used safely, without intervention, in conjunction with
conventional treatments to fight cancer. Herbs that strengthen the immune system and
support major waste-removing organs (the liver, kidneys and lymphatic systems) are
especially useful in fighting cancer.
ASTRAGALUS PLATINUM DRUG

• Astragalus membranaceous herb


• Platinum drug used in veterinary
is an immuno-stimulant; thus it can oncology such as Cisplatin behaves
be used to boost your animal immune system. similarly to a bi-functional

This herb has several applications alkylating agent by producing cross


in cancer care: links in DNA.

 stimulate B-cells preferentially; Side effect:

 immune booster .  vomiting within six hours ;


 myelosuppression.

Astragalus membranaceous also was shown to increase survival times and


lessen chemotherapy’s side effects. In a study where lung cancers were treated with
platinum drugs the group treated with this herb lived longer and had fewer side
effects.
ECHINACEA ETOPOSIDE

• Echinacea herb is well-known for • Etoposide is a topoisomerase


its effectiveness in supporting and inhibiting chemotherapy drug that has
strenthening the immune system.
been used as an adjuvant low-dose drug
This herb has several applications
for palliative control of
in cancer care:
splenic hemangiosarcoma
 can boost T-cell;
 immune booster ; Side effect:

 increases production of the  Vomiting.


chemokines interleukin-8 and MCP-1.
A possible drug-herbal interaction between
Echinacea and Etoposide. A 61-year-old gentleman
newly diagnosed with nonsmall cell lung cancer
began concurrent chemoradiation with cisplatin and etoposide.
GREEN TEA TETRACYCLINE

• Green tea is an antioxidant and • Tetracycline is a broad spectrum


antibiotic that is used to treat a wide
astringent and has been shown to be
variety of infections caused by bacteria
an effective especially for some kind of
and other types of organisms.
stomach and skin cancers.
Side effect:
This herb has several applications
 vomiting;
in cancer care:
 nausea ;
 healthy immune ;
 diarrhea .
 immune booster.

One study involved a seven-year-old Labrador with lymphoma that was


treated with various antibiotics, including amoxicillin, tetracyclines had no effect
on helping. After considering other treatment options, the owner of the pooch
settled on green tea. After this the dog’s condition improved .
MISTLETOE DOXORUBICIN

• Mistletoe is commonly used to • Doxorubicin is a chemotherapy


treat cancer.
medication used to
This herb has several applications
treat cancer.
in cancer care:
Side effect:
 anti-tumor effects;
 toxic to normal cells ;
 immunomodulatory effect ;
 kidney toxin .
 anti-metastatic ;
 DNA protection .

Herb drug interactions has to be expected from the


exposition of cancer cells to chemotherapeutic drugs and VAE
simultaneously.
Cat’s Claw Bark
Azathiopirine
(Uncaria tomentosa).

• Cat’s Claw Bark (Uncaria • Azathiopirine disrupts the synthesis of

tomentosa) DNA and RNA

commonly use in modern herbal Side effect:

medicine as an immune stimulant.  DNA poison ;

This herb has several applications  it has the potential to cause mutation.

in cancer care:

 improve circulation ;
Cat's claw is taken at the same time as an immune-suppressing drug such as
 antitumor;
azathioprine, the drug may not work as well to prevent transplant rejection or to
control another condition it is intended to treat. Herbal and dietary supplements,
especially cat's claw, should be taken instead azathioprine is being used.
Tumeric Methotrexate

• Turmeric turns the entire • Methotrexate is classified as an anti-

drug-based medical model on its head metabolite medication.

by possessing hundreds of benefits. ‘Side effect:

This herb has several applications  leukopenia ;


 pharyngitis ;
in cancer care:
 oral ulcers ;
 anti-angiogenic properties ;
 abdominal distress ;
 antioxidant properties ;
 bleeding .
 antitumor properties ;

 decreases metastasis.
The study showed a significant anti-arthritic action and protection from
hematological toxicity with the combination treatment of methotrexate and
curcumin.
The use of cytostatics used in chemotherapy often induce
immunosuppression, as well as lymphotoxic effects, that are characterized by the
damage of blood and lymphatic organs.
The biochemical studies about the effects of chemotherapy on the
endocrine and lymphatic system have been extensively studied and a number of
researches have been undertaken to identify adjuvant substances that have non-
toxic, homeoterapeutical and immunostimulating properties.
Studies about the effects of chemotherapy have been extensively studied and a
number of researches have been undertaken to identify adjuvant substances that have
non-toxic, homeoterapeutical and immunostimulating properties.
The experimental research done with herbal extracts or active principles
isolated from herbs has shown that they can influence the immune response on several
pathways.
- stimulates non-specific immune system by activating complement serum and
stimulating neutrophil polymorphonuclear phagocyt and macrophages;
- specifically stimulates the immune system, involving both cellular and humoral
immune responses, immune response culminating in antibody production;
- influences immune response through hormonal modulation indirectly .