GLOBAL MARKET FOR TISSUE ENGINEERING TO REACH $89.7 BILLION IN 2016 Wellesley, Mass.

In a recent release, TISSUE ENGINEERING AND REGENERATION: TECHNOLOGIES AND GLOBAL MARKETS (HLC101A) from BCC Research (www.bccresearch.com), the global market for tissue engineering and regeneration products totaled nearly $60 billion in 2011. This market is expected to increase at a compound annual growth rate (CAGR) of 8.4% to reach $89.7 billion in 2016. The tissue engineering market can be broken down into three main regions the U.S, Europe, and the rest of the world. The U.S. region accounted for $26.8 billion in 2011, and after increasing at a CAGR of 8.5%, should reach $40.4 billion in 2016. The European region was valued at nearly $25.5 million in 2011 and, increasing at a CAGR of 7.2%, should reach $36.1 billion in 2016. The rest of the world totaled $7.5 billion in 2011, and by 2016, this region should account for nearly $13.2 billion, a CAGR of 11.9%. Tissue engineering incorporates facets of biology, medicine, and engineering to create products and devices that will improve or replace biological functions. The development of tissue-engineered products involves cell and material combination with engineering methods. Although the term covers a broad range of applications, in practice, tissue engineering is closely associated with applications that repair or replace portions of tissue or whole tissues such as bone, cartilage, blood vessels, bladder, and skin. The outlook should be positive for tissue engineering as the many advances in this field will have enormous impact on quality of life for many patients by restoring, maintaining, and enhancing tissue and organ functions. Another positive is that tissue engineering has not only therapeutic but also diagnostic value. Artificial cellular structure can serve as an in vitro model for studies in drug metabolism, toxicity, and pathogenicity. Despite these obvious advantages, this market is developing at a slow pace. After the introduction of skin substitutes and cartilage regeneration products in the last 10 years, little progress has been made, and some of the products have been

discontinued. One of the main reasons for slow development is the biological complexity of growing organs and tissue replacements. Furthermore, current technologies are not cost-efficient enough to make these products effective alternatives. This report is intended for business development professionals, entrepreneurs, and other investment groups in order to fully understand and evaluate properly each segment in the tissue engineering and regeneration industry. Additionally, the report will be useful to the pharmaceutical and biopharmaceutical industries, clinics, hospitals, and research institutes involved with or interested in the field of tissue engineering. SUMMARY FIGURE GLOBAL MARKET FOR TISSUE ENGINEERING AND REGENERATION PRODUCTS, 2009-2016 ($ MILLIONS)

Source: BCC Research Data and analysis extracted from this press release must be accompanied by a statement identifying BCC Research LLC, 49 Walnut Park, Building 2, Wellesley, MA 02481, Telephone: 866-285-7215; Email: editor@bccresearch.com as the source and publisher, along with report number, which can be found in the first paragraph of this release. Thank you.