DRUG STUDY DRUG DRUG CLASS THERAPEUTIC ACTIONS y A partial agonist or antagonist at alpha receptors; as a result, it increase the

strength , duration , and frequency of uterine contractions INDICATIONS CONRAINDIC ATIONS AND CAUTIONS y Contraindicate d with allergy to Methylergono vine , hypertension, toxemia, lactation, pregnancy y Use cautiously with sepsis, obliterative vascular disease, hepatic or renal impairment ADVERSE EFFECTS CNS: dizziness, headache, tinnitus, diaphoresis CV: hypertensi on, palpitation, chest pain, dyspnea GI: nausea, vomiting NURSING RESPONSIBILITY y Monitor postpartum women for BP changes and amount and character of vaginal bleeding Discontinue if signs of toxicity occurs Avoid prolong use of the drugs Report difficulty in breathing , headache, numb or cold extremities, or severe abdominal crampin

Methylergonovine maleate Methergine

Oxytoxin

Paracetamol

Antipyretic Analgesic

y Routine management after delivery of placenta y Treatment of post partum atony and hemorrhage , subinvolutio n of the uterus y Uterine stimulation during the second stage of labor following the delivery of anterior shoulder , under strict medical supervision y Reduces fever y Analgesicby acting antipyretic in directly on the patients with hypothalamic aspirin heat allergy,

y y

Contraindica ted with allergy to acetaminoph en.

CNS: Headache CV: Chest pain,

Monitor liver function studies; may cause hepatic toxicity. Monitor renal

regulating center to cause vasodilation and sweating , which helps dissipate heat

hemostatic disturbances, bleeding diatheses, upper GI disease, gouty arthritis - Common cold, flu, other viral and bacterial infections with pain and fever - Unlabeled use: Prophylactic for children receiving DPT vaccination to reduce incidence of fever and pain

- Use cautiously with impaired hepatic function, chronic alcoholism, pregnancy, lactation.

dyspnea, myocardial damagewhen doses of 58 g/day are ingested daily for several weeks or when doses of 4 g/day are ingested for 1 yr GI: Hepatic toxicity and failure,jaundi ce GU: Acute kidney failure, renal tubular necrosis Hematologic: Methemoglob inemia cyanosis; hemolytic anemia hematuria, anuria; neutropenia, leucopenia,

function studies; albumin indicates nephritis - Monitor blood studies, especially CBC and pro-time if patient is on long-term therapy. - Check I&O ratio;decreasing output may indicate renal failure. -Assess for fever and pain - Assess hepatotoxicity: dark urine, claycolored stools - Assess allergic reactions: rash urticaria

pancytopenia, thrombocytop enia, hypoglycemi a Hypersensitiv ity: Rash, fever Amoxicillin trihydrate Antibiotic Bacteriacidal: inhibits synthesis of cell wall sensitive organism, causing cell death. y Infections y Contraindicate due to d with susceptible allergies to strains of penicillin, haemophilus cephalosporins influenza, or other Escherichia allergens coli , y Use cautiously neisseria with renal gonorrhea. disorder, lactation Unlabeled use: Chlamydia trachomatis in pregnancy CNS: lethargy, hallucination, seizures. GI: glossitis, stomatitis, gastritis, sore mouth, nausea, vomiting, diarrhea, abdominal cramps, GU: nephritis Hematologic: anemia, thrombocytop enia, leucopenia, prolong bleeding time Hypersensitiv ity: rash,fever y Give in oral preparation only: amoxicillin is not affectrd by food. Use corticosteroi ds or antihistamin s for allergic reactions. Take full course of therapy, dont stop because you feel well.

Folic acid

Folic acid Vitamin supplement

Required for nucleoprotein synthesis and maintenance of normal erythropoiesis

Treatmen t of megalobl astic anemia due to sprue. Nutrition al deficienc y, pregnanc y, infancy and childhoo d.

Contrain dicated with allergic to folic acid preparati ons, perniciou s, aplastic, normocyt ic anemia. Use cautiousl y during lactation

Hypersensitiv ity: allergic reactions Local: pain and discomfort at injection site

Administer orally if possible Monitor patient with hypersensiti vity reactions, especially if drug previously taken. Keep supportive equipment and emergency drugs readily available in case of serious respomse