Documentos de Académico
Documentos de Profesional
Documentos de Cultura
With the current widespread overuse of antibiotics, we are forcing bacteria to genetically change to survive. This
antibiotic Darwinism has led to numerous highly resistant strains of bacteria that now threaten
to create a Post-Antibiotic Era.
Several factors are associated with emergence of resistance among organisms.(more detail in Fig. 33-1. )
1. Widespread, inappropriate use of broad-spectrum antibiotics, especially in daycare centers and ICUs.
(e.g. treatment of viral illnesses with antibiotics).
2) Use of antibiotics in animal husbandry and fisheries to prevent infection and increase animal growth.
3) Excessive use of antimicrobial preparations in soaps and cleaning solutions in non-healthcare
facilities.
4) Increased numbers of immunocompromised patients requiring prolonged courses of antibiotics.
5) Prolonged survival of debilitated patients.
6) International travel promoting the movement of resistant bacteria (e.g. Mycobacterium tuberculosis).
7) Poverty leading to inadequate antibiotic usage because of the increasing expense of adequate antimicrobial
therapy.