DRUG NAME DOSAGE MECHANISM OF INDICATION CONTRAINDICATION SIDE EFFECTS NURSING

ACTION RESPONSIBILITIES
Generic Name: 250mg/20ml Dobutamine increases Inotropic Drug is contraindicated with CNS: headache  Monitor CVP to assess
Dobutamine HCl In a 20 ml contractility and heart rate support in idiopathic hypertrophic vascular volume and
vial by stimulating β-adrenergic patients w/ subaortic stenosis and Musculoskeletal: cardiac
Brand Name: receptors in the cardiac hypoperfusion patients with hypersensitive mild leg pumping efficiency.
Dobutrex tissues. states in whom to drug or any of its cramps or tingling (Elevated CVP may
cardiac output is components sensation indicate disruption on CO,
Classification: ↑ H R, ↑ CO, and ↑ SV insufficient to as in pump failure or
Beta-Adrenerdic with minor effects to meet circulatory CV: angina, Pulmonary edma; low
Agonist HR. demands. hypertension, CVP may indicate
↓ elevated ventricular filling Abnormally hypotension, hypovolemia)
Inotropic increased increased heart rate,  Monitor ECG and BP
pressure and helps AV ventricular nonspecific chest continuously during drug
Pregnancy node filling pressures pain, administration because
Category: B conduction introduce the risk phlebitis marked increases in blood
of pulmonary pressure (systolic pressure
congestion & GI: N&V is the most likely to be
edema. affected) and heart rate, or
Respiratory: asthma the appearance of
attacks, arrhythmias or other
shortness of breath. adverse cardiac effects are
usually reversed promptly
Others: anaphylaxis, by reduction in dosage.
skin rash, pruritus of  Record I&O because
scalp, fever, Urine output and sodium
eosinophilia excretion generally
increase due to improved
cardiac output and renal
perfusion.
 Monitor glucose in
diabetics; increased
insulin may be needed.
 Drug is administered IV
to
improve cardiac function
thus
increasing BP and
improving
urine output.
 Report any significant
adverse effects such as
chest pain,
increase SOB, headaches
or
 IV site pain.

DRUG NAME DOSAGE MECHANISM OF INDICATION CONTRAINDICATION SIDE EFFECTS NURSING

ACTION RESPONSIBILITIES
Generic Name: AMIODARONE Amiodarone is a for patients with Contraindicated to patients CNS: Malaise,  Monitor BP carefully
Amiodarone HCl 50MG/ML 3ML class III poor LV function with AV or SA block, sinus fatigue, dizziness, during infusion and slow
Single Dose Vial or patients with bradycardia, sick sinus the infusion if significant
Brand Name:
antiarrhythmic agent frequent syndrome except when used
tremors, ataxia, hypotension occurs;
Cordarone which inhibits ventricular in conjunction w/ a paresthesias, lack bradycardia should be
stimulation, ectopics post MI pacemaker; history of thyroid of coordination treated by slowing the
Classification: prolongs action although did dysfunction; iodine infusion or discontinuing
Antiarrythmic, potential and reduce intolerance, severe arterial CV: Cardiac if necessary. Sustained
Class III "arrhythmia hypotension, CV collapse, monitoring is essential
refractory period in deaths" and acute cardiac insufficiency.
arrhythmias,
because drug has an
Pregnancy myocardial tissues. effective against Combined therapy w/ drugs congestive heart unusually long half-life.
Category: D It blocks Na most which may induce torsades failure, cardiac  Baseline and periodic
channels, prolonging tachyarrhythmias de pointes. Pregnancy, arrest, assessments should be
myocardial lactation. Childn <3 yr. hypotension made of liver, lung,
cell action potential thyroid, neurologic, and
GI function because it
and refractory EENT: Corneal may cause thyroid
period. microdeposits function test
(photophobia, dry abnormalities in the
It also decreases AV absence of thyroid
conduction and sinus
eyes, halos,
blurred vision); function impairment.
node function. It may  If elevations persist on
also be a coronary ophthalmic AST and ALT or if they
vasodilator that has a abnormalities are 2–3 times above
driect effect on smooth including normal baseline readings,
muscle, and Calcium
permanent reduce dosage or
channel blockade withdraw drug promptly
blindness
to prevent hepatotoxicity
and liver damage.
Endocrine:  Anticipate possible CNS
Hypothyroidism symptoms within a week
or after amiodarone therapy
hyperthyroidism begins. Assess severity of
symptoms like proximal
muscle weakness, a
GI: N&V, common side effect,
anorexia, intensified by tremors
constipation, presents a great hazard to
abnormal liver the ambulating patient so
 function tests, supervise and assist them.
liver  Drug may be taken with
or without food. (Take
toxicity consistently w/ or without
meals. Take w/ meals if
Respiratory: high dose or to reduce GI
Pulmonary discomfort.)
toxicity-  Monitor for safe and
pneumonitis, effective serum levels
(0.5–2.5 mcg/mL)
infiltrates  Doses of digoxin,
(shortness of quinidine, procainamide,
breath, cough, phenytoin, and warfarin
rales, wheezes) may need to be reduced
one-third to one-half
Other: when amiodarone is
Photosensitivity, started.
angioedema  Auscultate chest
periodically or when
patient complains of
respiratory symptoms and
observe for breathing
pattern and note for
diminished breath sounds,
rales, pleuritic friction
rub. Drug-induced
pulmonary function
problems must be
distinguished from CHF
or pneumonia so keep
physician informed.

DRUG NAME DOSAGE MECHANISM OF INDICATION CONTRAINDICATION SIDE EFFECTS NURSING

ACTION RESPONSIBILITIES
Generic Name: AMINOPHY Aminophylline is a To prevent and Drug is contraindicated with CNS: Nervousness,  Monitor and observe
AMINOPHYLLI LLINE combination of theophylline relieve Hypersensitivity to xanthine restlessness, patients receiving
NE 25MG/ML and ethylenediamine. symptoms of derivatives or to depression, insomnia, parenteral drug for S&S
Brand Name: 10ML VIAL Ethylenediamine is inactive; acute bronchial ethylenediamine component; irritability, headache, of toxicity (generally
Corophyllin it increases the solubility of asthma and cardiac arrhythmias. Safety dizziness, muscle related to theophylline
Classification: theophylline in water. treatment of during pregnancy (category hyperactivity, serum levels over 20
BRONCHODIL Theophylline relaxes bronchospasm C) or lactation is not convulsions. mg/mL) like hypotension,
ATOR bronchial smooth muscle. associated with established. arrhythmias, and
(RESPIRATOR chronic CV: Cardiac convulsions until serum
Y SMOOTH bronchitis and arrhythmias, theophylline stabilizes.
MUSCLE emphysema.. tachycardia (with  Monitor & record
RELAXANT) rapid IV), vital signs and I&O
hyperventilation,
Pregnancy chest pain, severe beca. a sudden, sharp,
Category: c hypotension, cardiac unexplained rise in
arrest heart rate may
indicate toxicity.
GI: Nausea,  Watch out for toxicity In
vomiting, anorexia, Older adults, acutely ill,
hematemesis, and patients with severe
diarrhea, epigastric respiratory problems,
pain. liver dysfunction, or
pulmonary edema because
they are at greater risk
due to reduced drug
clearance
 Watch out for Children
that appear more
susceptible to CNS
stimulating effects of
xanthines (nervousness,
restlessness, insomnia,
hyperactive reflexes,
twitching, convulsions).
Dosage reduction may be
indicated.

DRUG NAME DOSAGE MECHANISM OF INDICATION CONTRAINDICATION SIDE EFFECTS NURSING

ACTION RESPONSIBILITIES
Generic DOPAMINE Dopamine stimulates For acute heart Drug is contraindicated with CNS: Headache  Monitor blood pressure,
Name: 80MG/ML in dopaminergic receptors at failure. Hypersensitivity to the drug, pulse, peripheral pulses,
a 5ML VIAL lower doses producing renal patients with CV: Ectopic bets, and urinary output at
DOPAMINE and mesenteric vasodilation Pheochromocytoma, intervals prescribed by
HYDROCH while at higher doses uncorrected tachycardia, physician because precise
LORIDE stimulate both dopaminergic tachyarrhythmias, ventricular anginal measurements are
and β-adrenergic receptors fibrillation. pain, palpitations, essential for accurate
Brand Name: producing cardiac hypotension, titration of dosage.
dopastat stimulation and renal  Report the following
vasodilation. It increases vasoconstriction, indicators promptly to
Classification:
alpha- and beta- heart rate and force of dyspnea, physician for use in
adrenergic contraction. bradycardia, decreasing or temporarily
agonist hyper tension, suspending dose: Reduced
(sympathomimet urine flow rate in absence
widened QRS. of hypotension; ascending
ic)
Pregnancy tachycardia;
Category: c GI: Nausea, dysrhythmias;
vomiting disproportionate rise in
diastolic pressure (marked
decrease in pulse
Other:, pressure); signs of
piloerection, peripheral ischemia
azotemia, (pallor, cyanosis,
mottling, coldness,
gangrene complaints of tenderness,
with prolonged pain, numbness, or
use burning sensation).
 Monitor therapeutic
effectiveness like
improvement in vital
signs and urine flow, loss
of pallor, increase in toe
temperature, adequacy of
nail bed capillary filling,
and reversal of confusion
or comatose state.


DRUG NAME DOSAGE MECHANISM OF INDICATION CONTRAINDICATION SIDE EFFECTS NURSING

ACTION
Generic Name: ATROPINE Atropine is an
ATROPINE SULFATE anticholinergic agent which
SULFATE 1MG/ML in a competitively blocks the
Brand Name: , 1ML VIAL muscarinic receptors in
Atropisol peripheral tissues such as
Classification the heart, intestines,
anticholinergic bronchial muscles, iris and
Pregnancy secretory glands. Some
Category: c central stimulation may
occur. Atropine abolishes
bradycardia and reduces
heart block due to vagal
activity. Smooth muscles in
the bronchi and gut are
relaxed while glandular
secretions are reduced.
RESPONSIBILITIES
Adjunct in Drug is contraindicated to CNS: Headache,  Monitor vital signs. HR is a
symptomatic
patients with Glaucoma, ataxia, dizziness, sensitive indicator of patient's
treatment of GI response to atropine. Be alert to
disorders and spastic chronic respiratory disease, excitement,
changes in quality, rate, and
disorders of biliary sick sinus syndrome, irritability, rhythm of HR and respiration
tract. thyrotoxicosis, cardiac convulsions, and to changes in BP and
failure, pyloric stenosis, drowsiness, fatigue, temperature.
suppress salivation,
perspiration, and
prostatic hypertrophy. weakness; mental
respiratory tract depression,  Be aware that Postural
secretions; to reduce confusion, hypotension occurs when patient
incidence of disorientation, ambulates too soon after parenteral
laryngospasm, reflex administration due to Initial
bradycardia
hallucinations. CV: paradoxical bradycardia following
arrhythmia, and Hypertension or IV atropine usually lasts only 1–2
hypotension during hypotension, min
general anesthesia. ventricular  Frequent and continued use of
eye preparations, as well as
For sinus bradycardia
tachycardia, overdosage because it can have
or asystole during palpitation, systemic effects and Some atropine
CPR or that is paradoxical deaths have resulted from systemic
induced by drugs or bradycardia, AV absorption following ocular
toxic substances administration in infants and
dissociation, atrial or children.
ventricular
fibrillation. GI: Dry
mouth with thirst,  Monitor I&O, especially in older
dysphagia, loss of adults and patients who have had
taste; nausea, surgery bec drug may contribute
to urinary retention so Palpate
vomiting, lower abdomen for distention.
constipation, delayed And Have patient void before
gastric emptying, giving atropine.
antral stasis, paralytic
ileus. Urogenital:
Urinary hesitancy
and retention,
dysuria, impotence.
Skin: Flushed, dry
skin; anhidrosis, rash,
urticaria, contact
dermatitis, allergic
conjunctivitis, fixed-
drug eruption.
Special Senses:
Mydriasis, blurred
vision, photophobia,
increased intraocular
pressure, cycloplegia,
eye dryness, local
redness.