DRUG STUDY

DOSE,
GENERIC BRAND MECHANISM CONTRA- SIDE ADVERSE NURSING
CLASSIFICATION ROUTE AND INDICATIONS
NAME NAME OF ACTION INDICATIONS EFFECTS EFFECTS CONSIDERATION
FREQUENCY
Amoxicillin Amoxil, Antibiotic 500mg cap / Prevents Treatment of Hypersensitivity to diarrhea, Dizziness, Obtain patient
Amoxil oral / every 8 bacterial cell infections of penicillins, dizziness, fatigue, history of allergy.
forte,Axmel, hours wall synthesis respiratory cephalosporins or heartburn, insomnia,
Daisamox during tract, skin and imipenem. Not insomnia, urticaria, Assess for bowel
replication. skin structures, used to treat nausea, abnormal patterns; bloody
Bactericidal. genitourinary severe pneumonia, itching, taste diarrhea, cramping
tract, otitis empyema, vomiting, sensation,
media, bacteremiaq, confusion, gastritis, Assess bowel
meningitis, pericarditis, abdominal anorexia, patter and signs of
septicemia, meningitis and pain, easy nausea, dehydration
sinusitis, purulent or septic bruising, vomiting.
bacterial arthritis durin g bleeding, Assess for allergic
endocarditis acute stage. rash, and reaction during
prophylaxis. allergic treatment.
reactions.
 DOSE,
GENERIC BRAND CLASSIFI- MECHANISM OF CONTRA- SIDE ADVERSE NURSING
ROUTE AND INDICATIONS
NAME NAME CATION ACTION INDICATIONS EFFECTS EFFECTS CONSIDERATION
FREQUENCY

Ampicillin Ampicin, Antibiotic, 500mg/cap Interferes with cell Treatment of Hypersensitivity to Sensitivity Thromboplebitis Obtain patient history
Bactimed, Penicilin Every 6 hours wall synthesis of respiratory tract penicillins, phenomena at injection site, of infection before and
Celidam, susceptible and soft tissue cephalospo- are likely to dizziness, during therapy to
Eurocin, organisms, infections, rins or imepenem. occur in fatigue, assess response.
Picaplin preventing bacterial Oral form not used individuals insomnia,
bacterial meningitis, to treat severe hypersensitive reversible Monitor renal function;
multiplication, it septicemia and pneumonia, to penicillin; hyperactivity, urine output,
also renders the gonococcal emphysema, convulsive neurotoxicity, urinalysis; protein and
cell wall infections caused bacteremia, seizures with hallucina-tion, blood, BUN,
osmotically by susceptible pericarditis and high doses; laryngo-spasm, creatinine.
unstable and burst microorganisms; purulent or septic diarrhea, skin rashes,
due to osmotic prophylaxis in arthritis during nausea, itchy eyes, Assess for overgrowth
pressure. rape victims and acute stage. vomiting, decreases of infection: perineal
Deactivated by for bacterial pseudo hemoglobin, itching, fever,
beta-lactamase, endocarditis. membranous hematocrie, malaise, redness,
an enzyme colitis; severe RBC and WBC. pain, swelling,
produce by pain (following drainage, rash,
resistant bacteria. IM); phlebitis diarrhea or change in
(following IV); character of cough
skin rash. and sputum
 DOSE,
GENERIC BRAND MECHANISM OF CONTRA- SIDE ADVERSE NURSING
CLASSIFICATION ROUTE AND INDICATIONS
NAME NAME ACTION INDICATIONS EFFECTS EFFECTS CONSIDERATION
FREQUENCY
Ferrous Anemi-con, Iron Preparation 250mg cap/ Provides Iron deficiency Contraindicate Constipation, Nausea, Take the supplement
sulfate Ferglobin, oral/ Twice a elemental iron, an as a d in patients gastric epigastric with orange juice.
Brofesol day essential supplement with irritation, pain,
component in the nausea, Enteric coated
during hemosidero- vomiting,
formation of abdominal products reduce GI
hemoglobin pregnancy sis, primary cramps, constipation ,
prevention of hemochromato black stool, upset but also
anorexia,
iron deficiency. sis, hemolytic vomiting, diarrhea and reduce amount of
anemia, peptic diarrhea, dark- anorexia iron absorbed.
ulceration colored stools.
ulcerative These effects *Others: Stools may turn
may be black
colitis, or
minimized by Temporarily
regional adminis- stained teeth Monitor hemoglobin
enteritis and in tering from liquid level, reticulocyte
those receiving preparations forms count during
repeated blood as a coated
tablet. Soluble therapy.
transfusion.
Use cautiously iron
preparations
in long term
may stain the
basis. teeth.
 DOSE,
GENERIC BRAND MECHANISM OF CONTRA- SIDE ADVERSE NURSING
CLASSIFICATION ROUTE AND INDICATIONS
NAME NAME ACTION INDICATIONS EFFECTS EFFECTS CONSIDERATION
FREQUENCY
Mefenamic Dolfenal, Anti-inflammatory: 500mg/tab / Inhibits reuptake of Moderate to Hypersensitivity Constipation; Dizziness,V Advise patient that
Acid Ponstan, Analgesic oral / every 6 serotonin norepine- moderately with drugs, acute diarrhea; isual distur- the drug works best
Gardan hours phrine CNS severe pain intoxication with dizziness; gas; bances, when taken before
headache;
alcohol, physical Nausea pain becomes
heartburn;
opoid nausea; and severe.
dependence. stomach upset. vomiting,Uri
nary Recommend the
Retention,P abstinence from
ruritus alcohol while taking
the medication

Caution the patient

that drugs can
cause dependence

DOSE,
GENERIC BRAND MECHANISM CONTRA- SIDE ADVERSE NURSING
CLASSIFICATION ROUTE AND INDICATIONS
NAME NAME OF ACTION INDICATIONS EFFECTS EFFECTS CONSIDERATION
FREQUENCY
Metronidazole Dazolex, Amebicide, 500mg/tab Inhibits DNA Infections in Contraindicate Rash, Convulsive Assess for allergic
Metrinox, Antibacterial, Every 8 hours synthesis in the intra- d with Swelling face; seizure; reactions, rash,
 Flagyl, Antibiotic, specific Abdominal, hypersensitivit Anemia, peripheral urticaria, pruritus.
Frotin, Antiprotozoal anaerobes, skin and skin y to metronida- Neutropenia; neuropathy,
Metrolag, causing cell structure, bone zole; Anaemia, rash, Assess for
Tricomycin, death, and joint, pregnancy ( do Neutropenia; pruritus, GI overgrowth of
Anerobia antiprotozoal, gynecologic,ba not use for Urticaria; discom-fort, infection: perineal
trichomonacid cterial trichomo-niasis Pruritus, anorexia, itching, fever,
al, amebicidal; septicemia, for first Urticaria; nausea, malaise, redness,
Biochemical CNS, lower trimester). Use Hematuria, furred pain, swelling,
mechanism of respiratory cautiously with Vasculitis; tongue, drainage, reash,
action is not system and CNS diseases, Dyspnoea, metallic diarrhea or change
known. endocarditis. hepatic Pyrexia, taste, in character of cough
Treatment disease, Rash; Headache, and sputum
susceptible candidiasis, Hepatitis, weakness,
protozoal blood Lethargy; dizziness, Monitor bowel
infections and dyscrasias, Brain edema, diarrhea, pattern, discontinue
in the lactation. Confusional psychiatric drug if severe
treatment and Bacterial state, disorder and diarrhea occur.
prophylaxis of vaginosis, Dysarthria, watery eyes.
anaerobic Candida Nervous
bacterial albicans, and system
infections. other fungal disorder;
Anaerobic infections.
infections,
trichomoniasis,
amoebiasis,
giardiasis.

DOSE, NURSING
GENERIC BRAND MECHANISM OF CONTRA- SIDE ADVERSE
CLASSIFICATION ROUTE AND INDICATIONS CONSIDERATIO
NAME NAME ACTION INDICATIONS EFFECTS EFFECTS
FREQUENCY N
Nalbuphine Nubain Opioid agonist- 5mg/ IV / as Binds with opiate Relief of Hypersensitivit Constipatio Sedation, Assess patient
hydrochloride antagonist needed receptors in the moderate to y. Pregnancy n; drowsiness, underlying
analgesic CNS: ascending severe pain; (only if used dizziness; sweating, condition before
pain pathways in for pre for prolonged drowsiness; nausea, dry therapy obtains
limbic system, operatively periods or in dry mouth; mouth and drug history.
thalamus, analgesia, high dosage at feeling of a dizziness,
midbrain, supplement to term). whirling headache Assess pain
hypothalamus, balance motion; and characteristics
altering perception anesthesia, headache; vomiting. (location,
of and emotional surgical nausea; intensity, type)
response to pain. anesthesia, sweating/cl before
Relieves pain. obstetrical ammy skin; administration
analgesia. vomiting. and after
treatment.

Monitor allergic
reactions; rash,
pruritus and
urticaria.

Monitor vital
signs. Report
respiratory rate of
<10 per minute.

DOSE,
GENERIC BRAND CLASSIFI- MECHANISM OF CONTRA- SIDE ADVERSE NURSING
ROUTE AND INDICATIONS
NAME NAME CATION ACTION INDICATIONS EFFECTS EFFECTS CONSIDERATION
FREQUENCY

Ranitidine Entac, Anti- 500mg/cap Potent anti-ulcer Short- term GI malignancy, Headache, Malaise, Assess patient for
Incid, ulcerative; Oral / every 8 drug that treatment of severe renal dizziness, dizziness, epigastric or
 Intac, gastrointest hours competitively and active duodena impairment, malaise,insom insomnia, and abdominal pain and
Ceranid, inal agent; reversibly inhibits ulcer; pregnancy, nia, vertigo, vertigo. Rare frank or occult blood
Cygran anti- histamine action maintenance lactation, patient mental cases of in the stool, emesis,
secretory at H2i receptor therapy for with history of confusion, reversible or gastric aspirate.
(H2- sites on parietal duodenal ulcer porphyria agitation, mental
receptor cells, thus patient after depression, confusion, Arrange for regular
antagonist) blocking gastric healing of acute hallucination agitation, follow-up, including
acid secretion. ulcer; treatment on older depression, and blood tests to
Indirectly reduces of adults, hallucinations evaluate effects.
pepsin secretion gastriesophageal bradycardia; have been
but appears to reflux disease; Occasionally reported, Monitor creatinine
have minimal short term reversible predominantly clearance if mental
effect on fasting treatment of hepatitis; in severely ill dysfunction is
and postprandial active, benign rarely elderly patients. present or suspected.
serum gastrin ulcer; treatment agranulocytosi Rare cases of
concentrations or of pathologic GI s; acute reversible Be alert on early
secretions of hypersecretory pancreatitis, blurred vision signs of
gastric intrinsic conditions; arthralgia, suggestive of a hepatotoxicity;
factor or mucucs. heartburn myalgia, change in jaundice (dark urine,
treatment hypersensitivit accommodation pruritus, yellow sclera
y; reversible have been and skin).
skin rash reported. Rare
leukopenia reports of
and reversible
thrombocytope involuntary
nia; motor
constipation, disturbances
diarrhea, have been
nausea, received.
abdominal
pain.

DOSE,
GENERIC BRAND CLASSIFI- MECHANISM CONTRA- ADVERSE NURSING
ROUTE AND INDICATIONS SIDE EFFECTS
NAME NAME CATION OF ACTION INDICATIONS EFFECTS CONSIDERATION
FREQUENCY
Tramadol Milador, Analgesic 50g / oral/ Centrally acting Tramadol Hypersensitivity. Migraine and Vasodilation, Assess for
HCl Gesidol, every 6 hours analgesicnot hydrochloride Acute intoxication Speech dizziness, hypersensitivity
Tradonal, chemically tablets are aith alcohol, disorders.Gas- headache, reaction; pruritus,
Tramal related to opioids indicated for the hypnotics, trointestinal sleep disorder, rash.
but binds to mu- management of centrally acting bleeding, Hepatitis, seizure,
opioid receptor moderate to analgesics, Stomatitis, Liver sweating, Assess in changes
and inhibits moderately severe opioids, or failure .Dizziness, diarrhea, of bowel
reuptake of pain in adults. psychotropic headache, constipation, pattern.Increase
norepinephrine agents. drowsiness, blurred anorexia, dry diet bulk and oral
and serotonin. vision, upset mouth, urinary fluids and to
stomach, vomiting, retention and prevent
and diarrhea. Fast frequency. constipation.
heartbeat, redness,
swelling, and
itching of the face,
numbness or
tingling of the
hands and feet,
difficulty breathing,
changes in
urination, seizures.