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Ionising Radiation
The standard unit of absorbed dose was the rad (plural also is rad),
where 1 rad = 100 erg per gram.
The SI unit for absorbed dose is the gray (Gy) , 1 Gy = 1Joule / kg.
E D E E E L E R
DR
RBE X
DX
In order to account for this, the ICRP (publication number 60, 1990)
provided a list of Tissue Weighting Factors, (WT) for the organs and
tissues which are susceptible to the main biological radiation damage.
The Effective Dose (HE) is a way of determining the
whole-body biological damage due to radiation exposure of different
types to different types of the body. This is given by the weighted
sum of the equivalent dose for that type of radiation, multiplied by the
tissue weighting factors for that particular area of the body, HT.
Thus
H W H
E
T
T T
Particle Fluence rate () : is the rate of particle fluence with respect
to time. t and thus has units of particle/m2s.
Energy Fluence Rate ( is the quotient of the energy fluence with
respect to time, i.e., = t . Units are Joules/m2s.
while
kerma is the energy transferred from the original particle (or photon)
in the same unit volume.
MSc-REP Regan Dosimetry 28
Absolute Methods of Dosimetry
Absolute methods of dosimetry can provide measurements for the
absorbed dose without the instrument (‘dosemeter’) being calibrated
in a known radiation field. (Most instruments give measurements
relative to calibrated primary or secondary standards).
1) the fraction () of the absorbed dose (D) which is channelled into
a given effect, and
2) the average energy (H) needed to produce a given effect (e.g.,
ionisation, chemical changes, nuclear reactions etc.) 29
MSc-REP Regan Dosimetry
Thus, the energy per unit mass going to any specific effect = D.
If this causes Ne subsequent effects per unit mass, and the average
energy required to produce the unit effect is H, then the total energy
required is the product of Ne and H, ie. Ne.H = D
D E Eext E Lext E Rext E Eint E Lint E Rint ELext
If radiation equilibrium exists, then E Eext E Lext E Lint
and therefore,
D E Eint E Rext E Rint
i.e the Dose (D) is the
energy from the loss in rest mass following radioactive decay minus
any increase in rest mass from external & internal radiation interactions,
or put another way
D E Eext E Lext E Rext
where E Eext E Lext must be positive since only part of the incident
radiation is absorbed and perfect radiation equilibrium is not achieved.
Note that for photon energies less than 1.022 MeV (the e+e- production
threshold), there are essentially NO CHANGES in REST MASS and
thus ERext 0 .
In this case, the absorbed dose arises from the difference between the
energy entering the volume and that leaving it.
MSc-REP Regan Dosimetry 37
Charged Particle Equilibrium
X-ray and -ray photons, and neutrons are uncharged. As such, they
are described as INDIRECTLY IONISING RADIATIONS since
they deposit their absorbed dose in matter by a 2-step process:
c c
E D E E E L E E E L E R
u u u
Note that there is no ‘rest mass’ term (ER) in the first square bracket
about since electrons and photons cause virtually no rest mass changes
in the normal expected energy ranges for these radiations.
If CHARGED PARTICLE EQUILIBRIUM (CPE) exists, then
EE c
E L
c
thus , E
EL 0 giving
E
c c
en is always smaller than since there are other effects which can
remove photons in the beam which do not necessarily impart energy
(e.g., bremsstrahlung, fluorescence, X-rays, Compton scattered photons
and pair production/ annihilation radiation.).
MSc-REP Regan Dosimetry 46
The linear attenuation coefficient can be reduced to allow for the escape
processes to give an expression for the LINEAR ENERGY TRANSFER
The linear attenuation coefficient is given by pe c pp
If we allow for escape secondary radiation related to each term, the
δ 2m0 c 2
linear energy transfer coefficient, μtr μ pe 1 μc 1-f s μ pp 1
E Eγ
γ
where is the mean energy of the characteristic X - rays ;
f s is the energy fraction in Compton collisions taken by the scattered photons
2m0 c 2 ( 1.022MeV)
fraction of the incident energy taken by e e - radiation.
Eγ
A (typically small) fraction, (g) of the kinetic energy which is transferred to
recoil electrons is re - radiated in the form of bremsstrahlung and does not
contribute to the local dose. This reduces the energy absorption coeff. further
en tr
thus, en tr 1 g and 1 g
MSc-REP Regan Dosimetry 47
Mass energy absorption
coefficients
en <
511keV
e- e- e-
e+
511keV
brem = bremsstrahlung
MSc-REP Regan Dosimetry 48
Mass attenuation coefficients for (A) Lead and (B) Water.
Taken from Alpen, p81-82.
Hence the energy absorbed in unit mass of air, (i.e. absorbed dose) is given by:
Dair = (1 - g)Te.
This produces Ni ion pairs in this unit mass and an additional gNi ion pairs externally due to
absorption of the escaping bremsstrahlung, giving a total of (1 + g)Ni ion pairs at a total
energy cost of Te.
Therefore, from the definition of W-value, we can write We = Te/(1 + g)Ni and thus:
Te = WeNi(1 + g).
Substituting for Te in the expression for the dose given above:
Since Te = WeNi(1 + g) and remembering that air-kerma, Kair, is defined as the initial kinetic
energy transferred per unit mass of air then
Kair = Te = WeNi(1 + g) and thus Kair = Dair/(1 - g).
MSc-REP Regan Dosimetry 50
The relative importance of the three major types of gamma-ray
interaction. The lines show regions of gamma-ray energy and the Z
(atomic number) of the absorber material for which the two
neighbouring effects are equal. Taken from Knoll p. 54
MSc-REP Regan Dosimetry 51
Worked Example:
A 8 MeV photon penetrates into a 200g mass of tissue and
undergoes a single, pair production interaction.
Both the e+ and e- particles created in this interaction dissipate all
their kinetic energy within the mass through secondary ionisation
and bremsstrahlung production.
Two bremsstrahlung photons of energy 1.1 and 2 MeV
respectively are produced and escape from the mass without further
interaction.
The positron, after expending all its kinetic energy
interacts with an ambient electron within the mass and they mutually
annihilate.
Both photons created in the annihilation radiation escape the mass
before further interaction.
Calculate
(i) the kerma and
(ii) absorbed dose the tissue receives from these interactions.
MSc-REP Regan Dosimetry 52
ANSWER:
Kerma is the sum of initial kinetic energies per unit mass of all charged
particles produced by the radiation.
In this case, this is the kinetic energy of the e+e- pair released, which is 6.978 MeV
(i.e. 8MeV- the rest masses of the electron and positron created (1.022 MeV)).
This is split evenly between the two particles such that they each have 3.489 MeV.
In this case, from the 8 MeV photon, an initial 6.978MeV of Kinetic Energy is released
in the medium by the initial pair production interaction.
This is followed by losses from the material of 1.1+2=3.1 MeV from the
bremsstrahlung interactions of the electron formed in the pair production interaction.
and 2 annihilation photons (1.022 MeV), all which escaped from the mass.
Thus of the initial energy interacting with the mass of 8 MeV, 4.122 MeV is not
absorbed in this tissue volume and thus, including the change in rest mass of the tissue
volume (from the creation of the e+e- pair = 1.022 MeV), the absorbed dose is given by
CPE CPE
1 2
D2
en / 2
D1
en / 1
D2 = S 2 .D where S 2
en / 2
1 1 1
en / 1
MSc-REP Regan Dosimetry 56
Consider a photon source placed D1 P D2
midway between 2 ‘infinite’ absorbers. ( /) (en /)2
en 1
The energy fluence E (in Jm -2), passing
through both absorbers must be the same, and thus we can write,
en en
In the CPE regions, D1 E and D2 E
1 2
en en
2 2
and therefore, D2 D1 1S D1 where 1S
2 2
en en
1 1
Thus, in a given radiation field, the dose in one medium (such as
biological tissue) can be derived from measurement in a second, more
practical medium (e.g., air), if the ratio of their mass energy
absorption coefficients is known (and if CPE is attained in both).
MSc-REP Regan Dosimetry 57
• A special case if an air-filled ion chamber is used.
• The W-value in air is 33.7eV/ion pair.
• Using this the absorbed dose in air corresponding to an exposure of
X = 1 roentgen can be calculated to be 87erg.g-1 (= 0.87 rad).
For photons of E=10 keV -> 3 MeV in soft tissues (made of H,C,O
and other low-Z elements), f = 0.92-0.97. Water has f = 0.90-0.96.
Bone (calcium, Z=20) has f = 3.6 for 10 keV and 0.92 @ 1MeV
MSc-REP Regan Dosimetry 58
Effective Atomic Numbers and’ Matching’
The dose in higher Z materials is much larger than in air (and other low-Z materials)
for lower X-ray energies due to the strong Z-dependence of the photoelectric effect
cross-section (pe~Zn/E4-5)
The photon attenuation coefficients, and the related energy absorption coefficients
are complex functions of E and atomic no.(Z), but over a RESTRICTED RANGE
of these two parameters, it is possible to represent the dosimetric behaviour of a
mixture of elements (such as in biological tissue) with the use of a single
parameter, called the EFFECTIVE ATOMIC NUMBER, Zeff.
For soft tissues over the range of diagnostic X-rays ( E=10-250 keV, Zeff=7.8).
This concept can be useful for estimating the degree of equivalence (or ‘matching’)
between real biological tissue and possible dosimetric media.
Although PERFECT MATCHING (i.e., 1S2=1.0) is only true for identical atomic
compositions, approximate matching is often good enough for radiation protection
purposes.
For example, tissue-equivalent gas mixtures can be used inside tissue-equivalent and
used inside natural body apertures to accurate dose measurements in radiotherapy.
MSc-REP Regan Dosimetry 59
Cavity Detectors
Consider a volume of gas contained in a cavity inside a solid material which
itself is surrounded by a third material. When CPE is attained in the cavity gas
and in the medium surrounding the ion chamber:
Dm = gSm Dg
If the absorbed dose gives rise to Jg (C.kg-1) of ionisation in the gas then the
dose in the gas is:
Dm = gSm Jg wg (Gy)
In this way the dose rate in the medium of interest can be derived from the
ion chamber current.
If the cavity wall, the cavity gas and the surrounding medium are all well
matched we have the homogeneous ion chamber case and gSm = 1.0.
Dair = X . We .
However in SI units we express exposure not in ion pairs per unit mass but in
coulombs per kilogram. (recall, The energy needed to produce an ion pair in air
is 33.7eV 33.7JC-1 (1eV = 1J * 1.6x10-19C-1)
The gas cavity must be small enough relative to the mass of the
solid absorber to leave the angular and velocity distributions of
the primary electrons unchanged.
unit area x
m 1.x g g x
E
electron track
c
dT
gas ΔE Δx
dx g
c c
ΔE 1 dT 1 dT is the mass stopping
Dg power for electrons.
Δm ρ g dx g ρ g dx g
MSc-REP Regan Dosimetry 63
Bragg-Gray Cavity Relation
Dg mass stopping power, and for the same electron fluence in the
surrounding medium we have.
c
1 dT
Dm
ρm dx m
By taking the ratio of these two expressions we find that,
Dm g s m Dg
where gsm is the ratio of mass stopping powers of the medium and the cavity
gas respectively. By measuring the ionisation per unit mass in the cavity, Jg:
Dm g s m J g w g
dE m S m dE g
m w J
dM m S g dM m
where Sm is the mass stopping power of the wall material and Sg is the
mass stopping power of the cavity gas and their ratio can be written by
Sm
m
Sg
w is the mean energy dissipated in the production of the ion-pair in the gas
and J = number of ions pairs created per unit mass in the gas.
MSc-REP Regan Dosimetry 65
Example Question:
Calculate the absorbed dose measured in a tissue-equivalent chamber
with a 1cm3 air filled cavity within the chamber which is exposed to a
source of 60Co gamma rays for 10 minutes.
A total of 2.25x109 electrons are collected from the chamber as a result
of ionization events in this period and the average mass stopping
power ratio of tissue to air is given by:
Sm
1.137 for 60Co gamma rays
Sg
USEFUL INFORMATION:
Average energy required to form an e--ion pair in air at STP = 34eV.
1eV = 1.6x10-19J ; the density of air at STP,
ρair = 1.293x10-6kg/cm3
SOLUTION:
dEm
m w J 1.137 34eV 1.6 10 J / eV
19
2.25 109 ions
0.0108Gy
dM m 1.293kg / cm 1cm
3 3
where N/t is the disintegration rate and Eav is the average energy
per disintegration of charged reaction products.
E = Q / N
= 0.00958 / 1.23x1010
= 7.79x10-13J
= 7.79x10-13J / 1.6x10-19 eVJ-1
= 4.87 MeV
MSc-REP Regan Dosimetry 70
Calorimetry
Thermometry
Semiconductors (thermistors) have temperature coefficients of
resistance of ~ -2 to -4 % per K.
Platinum resistance thermometers are more stable and
reproducible but are less sensitive (~ +0.4 % per degree).
Using thermistors, in order to measure T 10-3 K to ~ 1 % we
need to measure resistance changes of ~ 100 parts per billion
using a sensitive Wheatstone bridge.
Alternatively thermocouples such as copper/constantan with V =
50 V per K can be employed and the output voltage measured
with a potentiometer; several thermocouples in series generate a
larger potential difference.
Valence band
Formation Readout 74
MSc-REP Regan Dosimetry
Radiophotoluminescence Dosimetry
Typical optical absorption/emission curves for an RPL glass is shown
below.
UV
RPL Glass UV lamp
Luminscence
and UV scatter Optical filter
(removes visible)
UV filter (removes
PMT scattered UV)
There are two types of RPL glass (1) high-Z barium [enhances low energy
photon response (2) low-Z lithium or aluminium phosphate which is more
tissue equivalent.
RPL dosemeters are easily read-out and can be read out many times.
Electron
Trap Mg
TLD
Hole Ti photons
Trap
Valence band
Formation Readout
DC HV
Current amp P supply
Integrator M
T
Optical
} filters
IR
N2 flushing gas
MCS
Heater
dD0 1 1 dD0 1 1
Dt exp E t exp E t
dt E E dt E E
dD0 1
Dt 1 exp E t
dt E
= 7.77x10-9 J.s-1.g-1.cm2.mCi-1
= 2.80x10-5 J.g-1.cm2.hr-1.mCi-1
= 2.80 rad.cm2.hr-1.mCi-1
= 3.2 R.cm2.hr-1.mCi-1
ERext EDext
EEint ERint
EDint
ED = EK
C.P.E. D = K
Relectron
Kerma
Absorbed
Dose
e-
Build up
Region
MSc-REP Regan Dosimetry 103
Mass energy absorption
coefficients
For an air filled ion chamber, the absorbed dose for an
exposure of 1R = 0.87rad.
m
D m air S D air
D air 0.87 X
Hence for an exposure of X roentgen, the dose in rads is,
m
D 0.87 S X
m air
This can be written Dm = f.X where f = 0.87.airSm
which is called the rad per roentgen factor
MSc-REP Regan Dosimetry 104
Mass energy absorption coefficients
As radiation energy fluence passes through an
abosorber it decreases exponentially,
E = E0exp(-enx)
Differentiating gives:
dE/ = - E exp(- x) = - E
dx en 0 en en
μ en
dose, D E
ρ
μ tr
kerma, K E
ρ
tr/ = mass energy transfer coefficient
MSc-REP Regan Dosimetry 106
Mass energy absorption coefficients
μtr μpe 1 δ E γ μc 1 fs μpp 1 2moc 2 E γ
Additionally bremsstrahlung reduces this again,
μ en μ tr
μ en μ tr(1 g) and (1 g)
ρ ρ
Current NRPB
TLD and new
Harshaw TLD
LiF inserts
MSc-REP Regan Dosimetry 119
The Hp(10), “whole body” dose is measured by the detector behind the
domed part of the holder. The Hp(0.07), “dose equivalent to the skin
from both weakly and strongly penetrating radiations” is measured by
the detector behind the circular window.
Energies 5 keV to in excess of 40 150 keV to in excess of 10 Fast: 40 keV to in excess of 35 MeV
Detected MeV MeV Thermal: under 0.5 eV
Accreditation Accredited by NVLAP in all categories including VIII when neutron component is added, NVLAP
Lab Code 100518-0.
MSc-REP Regan Dosimetry 122
Neutron Dosemeters