Maintenance Guide

MW-96 Microplate Washer

CLINDIAG SYSTEMS B.V.B.A.
 Contents
1 DESCRIPTION................................................................................................... 1
1.1 BASIC PRINCIPLE......................................................................................... 1
1.2 STRUCTURE CHART...................................................................................... 1
2 OPERATIONAL ENVIRONMENT...................................................................... 1
3 WARNINGS AND PRECAUTIONS................................................................... 2
4 SERVICE AND MAINTENANCE...................................................................... 3
4.1 MAINTENANCE STAFF QUALIFICATIONS.......................................................... 3
4.2 TOOLS......................................................................................................... 3
4.2.1 General Tools......................................................................................... 3
4.2.2 Specific Tools......................................................................................... 3
4.3 DAILY MAINTENANCE...................................................................................... 4
4.4 WEEKLY MAINTENANCE................................................................................ 4
4.5 MONTHLY MAINTENANCE................................................................................ 4
4.6 YEARLY MAINTENANCE................................................................................... 5
5 MAIN COMPONENTS...................................................................................... 5
5.1 MAIN CONTROL PANEL................................................................................... 5
5.1.1 Functions................................................................................................ 5
5.1.2 Structure Chart...................................................................................... 5
5.1.3 Circuit Diagram...................................................................................... 6
5.2 TUBING SYSTEM............................................................................................. 6
5.2.1 Functions................................................................................................ 7
5.2.2 Structure Chart...................................................................................... 7
6 COMPONENT REPLACEMENT...................................................................... 7
6.1 FUSE REPLACEMENT...................................................................................... 7
6.2 CLEANING HEAD REPLACEMENT................................................................... 7
6.3 PIPELINE REPLACEMENT................................................................................ 8
6.4 SOLENOID VALVE REPLACEMENT................................................................... 8
6.5 VACCUM PUMP REPLACEMENT...................................................................... 8
7 Troubleshooting................................................................................................ 9
1 Description

1.1 Basic Principle

Based on principles of positive & negative pressure, microplate washer adds a
fixed amount of cleaning solvents into columns of the plate and rinses the plate
column by column under the control of stepper motor. After rinsing, the washer is
able to remove residues as many as possible on the plate.

1.2 Structure Chart

Structure chart of the instrument is shown as Figure 1-1 to explain how it
works.

Figure 1-1 Structure chart

2 Operational Environment
Operational environment requires:
-- Power Supply: 220V ±10%, 50Hz±2%
-- Fuse: 1A
-- Input Power: 100VA
-- Ambient Temperature: 10℃~40℃
-- Relative Humidity: ≤75%
-- Air Pressure: 86.0kPa~106.0kPa
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 -- Avoid dust, intense electromagnetic sources, corrosive gases, and
mechanical vibrations.
-- Reliable ground connection.

Note
-- Check and confirm that all plugs on the instrument are properly connected,
well grounded and reliable.
-- Make sure that the instrument is placed on a smooth and stable table.

3 Warnings and Precautions

-- Do not place or operate the instrument on an unstable table.
-- There are ventilating openings and pipeline interfaces at back panel. Make
sure to reserve a 20 cm-space at the back of instrument for colling down. Also do
not operate the instrument in a closed environment.
-- Check and confirm that the power socket is correctly installed and well
grounded.
-- Check and confirm that plugs on the instrument are properly connected, well
grounded and reliable.
-- Do not make physical concact with patients’ serums to avoid potential risks.
-- Waste solvents are harmful to human health, make sure to dispose them in
accordance with hospital regulations on dealing with harmful waste articles.
-- Make sure to use matched supply voltage on the instrument.
-- Be sure to cut off the power and turn off the instrument before repairing it.
Performing repairs with theinstrument running may result in electric shock or
coponent breakage, and shall be done by professional engineers.
-- Always use a specified fuse.
-- Switch off main switch before connecting wires and sockets. Failure to do so
may cause damage to instrument.
-- Do not get waste fluid into pumps and surge flask. Be sure to empty waste
fluid bottle after each use. Check if waste fluid is evacuated before instrument
starting up. Evacuate waste fluid before it rises above alert line.
-- Rinse pipelines with distilled water after each use. It is an effective way of
preventing solvent crystallization which may cause blockage in cleaning head.
-- Do not place objects onto working table to ensure smooth movement of
cleaning heads and microplate.
-- Remove cleaning heads from brackets before plugging or removing pipelines
connected to cleaning heads in order to prevent heads from being deformed.
-- Switch off the instrument and pull out power plug if you finish testing or won’t
use it for a long time.
-- Always use qualified cleaning solvents for rinsing.

4 Service and Maintenance

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 4.1 Maintenance Staff Qualifications
Service is only provided by Clindiag after-sale engineers or authorized
professionals.

4.2 Tools

4.2.1 General Tools

General tools for servicing:
-- 1 medium-sized screwdriver
-- 1 small screwdriver
-- 1 medium-sized slot-head screwdriver
-- 1 small slot-head screwdriver
-- 1 needle nose pliers
-- 1 set inner hexagon spanner
-- 1 150W electric iron
-- A pack of soldering tin
-- 1 digital multimeter
-- A pair of tweezers

4.2.2 Specific Tools

Specific tools for servicing:
-- Soft cloth
-- Neutral cleaner
-- Lubricants
-- Rubbing alcohol
-- Rubber gloves
-- Nozzle cleaner

4.3 Daily Maintenance

Daily maintenance steps are as follows:
-- Clean microplate washer’s operational environment.
-- Use a wet towel to clean the bracket.
-- Use a soft cloth with neutral cleaner to clean surface of the instrument.
-- Use a soft cloth to clean the screen.
-- Empty the waste fluid bottle.
Warning
-- When cleaning with detergent, be sure to wear safe-guard glasses, rubber
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gloves and strictly follow Warnings & Precautions on the bottle. If there is any
detergent dropped on your body, wash it with clean water and disinfectant
immediately. If necessary, go and see your doctor.
-- Be sure to empty waste fluid bottle without any delay. Failure to do so may
cause waste fluid to be pumped into vacuum pump and results in damage to
instrument.

4.4 Weekly Maintenance

Weekly maintenance steps are as follows:
-- Use a soft cloth with neutral cleaner to clean guide rods of the instrument.
-- Empty the bottles with cleaning solution, distilled water and waste fluid, and
then clean them.
Warning
-- Do not clean guide rods of the instrument with solution containing
hypochlorite. Failure to do so may result in permanent corrosion.
-- When cleaning with detergent, be sure to wear safe-guard glasses, rubber
gloves and strictly follow Warnings & Precautions on the bottle. If there is any
detergent dropped on your body, wash it with clean water and disinfectant
immediately. If necessary, go and see your doctor.

4.5 Monthly Maintenance

Monthly maintenance steps are as follows:
-- Use a soft cloth with neutral cleaner to clean guide rods of the instrument;
-- Do not forget to apply lubricants on guide rods after cleaning.
-- Calibrate mechanical parameters of the instrument.

Warning
-- Do not clean guide rods of the instrument with solution containing
hypochlorite. Failure to do so may result in permanent corrosion.
-- When cleaning with detergent, be sure to wear safe-guard glasses, rubber
gloves and strictly follow Warnings & Precautions on the bottle. If there is any
detergent dropped on your body, wash it with clean water and disinfectant
immediately. If necessary, go and see your doctor.

4.6 Yearly Maintenance

Monthly maintenance steps are as follows:
-- Replace drain pipes.
-- Replace priming pipes.
Note
-- Normally, drain pipes and priming pipes are guaranteed for one year.
However, term of service also depends on operating frequency and working
capacity of the pipes.
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 5 Main Components

5.1 Main Control Panel

5.1.1 Functions
Based on the principles of positive & negative pressure as well as its control
over vacuum pump, solenoid valves, horizontal and vertical motors, main control
panel is able to complete transfusing and rinsing of microplates.

5.1.2 Structure Chart

The structure chart of main control panel is shown as Figure 5-1.

Figure 5-1 Structure chart of main control panel

5.1.3 Circuit Diagram

The circuit diagram of main control panel is shown as Figure 5-2.

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 1 2 3 4

VCC D1 D2 D3 D4
FR107FR107FR107FR107
U1 VCC +24V

2
L297 U2

12Vs
L298N

VDD
CZ1 VCC

4
Vs
DC2-10

1
D M1_CLK M1_CLK18 4 5 D
1 M1_EN CLOCK A 6 7 Input 1 VCC R14 R24

1
2 M2_EN B 7 10 Input 2 2 OUT1A 22K 22K

1
3 M2_CLK CW1 17 C 9 12 Input 3 Out1
4 CW1 CW/CWW D Input 4 3 OUT1C R34

2
5 Out2
6 CW2 INH1 5 6 Enable A 10K osc1 osc2
GND VCC 19
7 N_PLATE_LOCATION HALF/FULL 8 11 13 OUT1B

2
8 N_AD_SYNC INH2 Enable B Out3 Vref2 C12 C22
9 N_FILTER_RESET reset1 20 14 OUT1D 332 332

1
10 RESET 14 SENS1 Out4

2
M1_EN 10 SENS1 R35
ENABLE
CZ2 470
7PIN/2.54 VCC 11 13

Sense A

Sense
GND
CONTROL SENS2

15
VCC

8 B

2
1 GND Vref1 15 SENS2

1
2 N_FILTER_RESET Vref GND2
3 OUT2A osc1 16 VCC
4 OUT2C OSC SENS1 SENS2 D5 D6 D7 D8

1
C 5 C
OUT2B FR107FR107FR107FR107

GND1

SYNC
HOME

1
6 OUT2D R15 R25

3
7 R12 R13 22K 22K

1
0.5/1W 0.5/1W
CZ4 GND home1 C10 C11

2
6PIN/2.54 104 104 reset1 reset2

2
1 VCC GND2
2 GND
3 +12V
4 GND1
+24V D9 D11 D13 D15 C13 C23
5
6 GND2 VCC FR107FR107FR107FR107 VCC 104 104
U3 VCC +24V

1
CZ5 L297 U4
12Vs

L298N R44

VDD
3PIN/2.54

1
10K

Vs
1 VCC
2 GND M2_CLK18 CLOCK A 4 5 Input 1 R16 R26
N_PLATE_LOCATION 6 7 10K 10K

2
3 B 7 10 Input 2 2 OUT2A Vref1
B CW2 17 C 9 12 Input 3 Out1 B

2
CZ6 CW/CWW D Input 4 3 OUT2C M1_EN M2_EN
4PIN/2.54 5 6 Out2 R45
VCC 19 INH1 Enable A
1 OUT1D HALF/FULL 1K
OUT1B 8 11 13 OUT2B
2 OUT1C INH2 Enable B Out3 VCC

2
3 OUT1A reset2 20 14 OUT2D
4 RESET 14 SENS3 Out4

2
M2_EN 10 SENS1 + EC1 EC2
ENABLE 470UF/35V 104
VCC 11 13 GND

GND
Sense A

Sense
+24V CONTROL SENS2 15
1

8 B
Vref2 15 SENS4

1
Vref GND2
+ EC5 osc2 16
OSC
470UF/35V SENS3 SENS4 D10 D12 D14 D16
GND2 FR107FR107FR107FR107
GND1

SYNC
HOME

1
2

R22 R23 Title

1

A A
0.5/1W 0.5/1W
GND home2 C20 C21
104 104 Size
2

GND2 A4
Date: 13-J
File: :
1 2 3 4

Figure 5-2 Circuit diagram of main control panel

5.2 Tubing System

5.2.1 Functions
Based on the principles of positive & negative pressure as well as its control
over vacuum pump and solenoid valves, tubing system is ale to complete
pipeline cleaning and liquid feeding.

5.2.2 Structure Chart

Structure chart of tubing system is shown as Figure 5-3.

6 Component Replacement

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 6.1 Fuse Replacement
Use the following steps to replace fuse when it is necessary:
-- Switch off the instrument.
-- The fuse is installed in a fuse box close to power switch at the back of the
instrument. Uncover the box lid and replace with a new fuse of the same
specifications.
-- Close fuse box lid and restart the instrument.
Note
-- Always use a specified fuse.
Warning
-- Always make sure to pull out power plug from the instrument to avoid getting
an electric shock when replacing fuse.

6.2 Cleaning Head Replacement

Use the following steps to replace cleaning heads if necessary:
-- Make sure the instrument is stopped.
-- Remove cleaning heads from brackets.
-- Remove the pipelines connected to cleaning heads.
-- Replace cleaning heads and connect them to pipelines of the same color.
-- Position cleaning heads on the brackets.
Note
-- Remove cleaning heads from brackets before plugging and removing the
pipelines connected to cleaning heads to prevent heads from being deformed.
-- Always connect pipelines to cleaning heads of the same color so as to avoid
damage to instrument.
-- Do not touch cleaning heads with bare hands! Be sure to wear rubber gloves
when replacing.

6.3 Pipeline Replacement

Use the following steps to replace priming and pipetting pipelines if necessary:
-- Switch off the instrument.
-- Disconnect pipelines connecting bottle caps to instrument.
-- Connect new pipelines to instrument and caps of the same color.
Note
-- Be sure to use pipelines of the same specifications for replacement. Failure
to do so may result in poor air tightness.
-- Always connect a pipeline to an interface of the same color to prevent
damage to instrument.

-- Do not touch cleaning heads with bare hands! Be sure to wear rubber
gloves when replacing.

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 6.4 Solenoid Valve Replacement
Use the following steps to replace a faulty solenoid valve:
-- Switch off the instrument
-- Open the upper cover.
-- Check and confirm the solenoid valve is faulty.
-- Disconnect the plug linking the faulty solenoid valve to main control panel.
-- Disconnect the pipelines on both ends of solenoid valve.
-- Remove the faulty solenoid valve from bracket and reinstall a new one.
-- Properly connect the original pipelines and plugs to the new solenoid valve.
-- Close upper cover and restart the instrument.
Note
-- Check air tightness after replacing solenoid valve.
-- Check if the plugs are properly connected to solenoid valve. Failure to do so
may cause damage to solenoid valve or reduce instrument performance.
-- Power from solenoid is not divided into positive or negative electrodes.

6.5 Vaccum Pump Replacement

Use the following steps to replace vacuum pump if necessary:
-- Switch off the instrument.
-- Open the upper cover.
-- Disconnect plugs connecting vacuum pump to main control panel.
-- Disconnect inlet and outlet pipelines of vacuum pump.
-- Remove the faulty pump from bottom plate and reinstall a new one.
-- Connect one pipeline from negative pressure interface of the instrument to
pump inlet and the other pipeline to pump outlet.
-- Connect plug of vacuum pump to main control panel.
Warning
-- Incorrect connection of pump inlet and outlet pipelines may cause damage to
vacuum pump.

7 Troubleshooting
Troubleshooting is listed in Table 7-1.
Table 7-1 Troubleshooting
Problem Cause Solution
The instrument Loose power plug or poor Check the instrument for any
fails to start contact loose plugs or sockets.

Blown fuse Replace the fuse.

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 No or less fluid Blocked syringe needle
from shot needle
of Cleaning head
Empty cleaning solvent
bottle
Air leakage results from
loose cleaning solvent bottle
cap or loose nuts inside the
cap
Cracked or wrinkled silicone
tube, or blocked pipeline
Broken solenoids
Broken vacuum pump
Too many residues Air leakage results from
after plate washing loose cleaning solvent bottle
cap or loose nuts inside the
cap
Foreign matters in long
needle
Blocked pipetting pipeline
Long needle of cleaning
head not inserted deep
enough to bottom of the
pore on plate
Excessive amount of
solvents added by short
needle of cleaning head into
pore of plate or excessive
pressure caused by too tight
pressure regulator valve
Too much distance between
long needle of cleaning
head and plate pore
Incorrectly aligned Improperly positioned plate
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Remove cleaning head, and
use a cleansing pin to clear
its needle before rinsing
pipelines.
Add cleaning solvent.
Tighten the cap and the nut
in it.
Replace cracked or wrinkled
pipelines.
Replace solenoids.
Replace vacuum pump.
Tighten the cap and the nuts
inside it.
Remove cleaning head, use
a cleansing pin to clear its
needle and rinse pipelines.
Clean up blockages in
pipetting pipe.
Readjust mechanical
parameters.
Readjust pressure regulator
valve.
Check seals and pipelines for
any leakage. Reinstall
pipetting pipe into pipe hole
of solenoid and readjust
mechanical parameters.
Reposition the plate.
Page 9 of 11
 cleaning head and Blockage between Clean horizontal guide rods.
microplate holes horizontal guide rods and
slider on leveling
mechanism impedes sliding.
Blockages between screw Clean vertical guide rods.
mandrel and screw, vertical
axis and screw, as well as
vertical axis and guide rail
on vertical mechanism
Imperfect motor or broken Replace motor.
motor
Loose or worn synchronous Adjust belt tightness or
belt replace belt.

The instrument Horizontal or vertical motor Replace motor.

fails in failure
initialization after No 24V output Measure voltage output.
staring up Perform replacement when it
is necessary.
Cleaning head is Broken optical coupler or Check connecting wire of
put into place after poor contact Optical coupler or replace
starting up, but Optical coupler.
noises are stilled
heard from motor
and can’t go to
next step
Short needle won’t Solenoids failure Replace faulty solenoids.
stop emitting fluid
after starting up

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 Exhaust nozzle Excessive fluid in waste fluid Switch off the washer
starts spraying bottle and surge flask is
immediately and empty
water after washer pumped into vacuum pump
staring up and spurts out along positive waste fluid bottle and surge
pressure pipelines.
flask. Connect waste fluid

bottle and surge flask to

instrument before restarting it

(cleaning solvent bottle can

be connected later). Allow the

washer to run idle for a

couple of minutes to fully

discharge waste fluid in

vacuum pump.
Cleaning solvents are Check and confirm pipelines
pumped into pumps due to are correctly connected.
wrongly connected positive
and negative pressure
pipelines.

Note
-- Only components provided by Clindiag or its distributors are allowed for
replacement.
-- If any unsolvable or repetitive errors arise, please contact Clindiag or its
distributors.
-- Do not touch pipetting pipe or cleaning heads with bare hands! Be sure to
wear rubber gloves when replacing.

END

CLINDIAG SYSTEMS B.V.B.A.

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