Facial Mesotherapy
15
Facial mesotherapy is a technique used to rejuvenate the skin
by means of intradermal or transdermal injections of variable
diluted agents such as multivitamin solutions, homeopathic
agents, and other bioactive substances that are thought to
improve the signs of skin aging [1].
The good results obtained with fat injection for skin
regeneration in cases of cancer surgery after radiotherapy
[2–4] extended the applications of fat and the stromal vascu-
lar fraction to the area of skin rejuvenation. In recent years
we have carried out studies both in the facial region and in
the rejuvenation of hands and have achieved significant
improvements in skin quality [5–9].
Although the precise role of fat or some of its components
in skin rejuvenation is not known, the results suggest an
angiogenic action with the formation of new capillaries as
well as the reorganization and formation of new elastic fibers
in the dermis [6–8].
To perform mesotherapy, we use emulsion, platelet-rich
plasma or vitamins either separately or in combination,
depending on the needs of each patient. We may only want to
perform mesotherapy with emulsion to regenerate and
improve the skin, or we may want to use it in combination
with platelets to obtain an immediate anti-inflammatory
effect if we have performed a facelift and aim to reduce the
swelling. We can add vitamins to the emulsion to nourish the
© Springer International Publishing Switzerland 2016
J.M. Serra-Renom, J.M. Serra-Mestre, Atlas of Minimally Invasive Facelift, DOI 10.1007/978-3-319-33018-1_15
dermis, or we might want to use the emulsion with platelets
and vitamins. These are the three most frequently used com-
binations (Fig. 15.1).
Once the most appropriate mix—emulsion + platelets,
emulsion + vitamins, and emulsion + platelets + vitamins—
has been chosen, we draw the tension columns throughout
the cheek in the shape of a curved fan from the zygomatic
arch downward toward the nasolabial folds covering the
entire cheekbone and then from this point upward through-
out the temporal region toward the temporalis crest
(Fig. 15.2).
This can also be done in the forehead or in any facial
region in which we want to nourish the facial skin. With a
23-G needle, we inject the emulsion mixture following these
divergent lines at half-centimeter intervals and in the dermis
2 mm apart, each with a small droplet of the preparation. At
the end we apply ointment or oil or cream to soothe the
treated region, for example, rosehip oil or a preparation of
aloe vera cream. Cold packs may also be useful. If the meso-
therapy is part of another treatment and the patient is already
sedated, no other anesthetic is required. If it is performed on
an outpatient basis, prior application of a topical anesthetic
and locoregional block of the infraorbital and temporal
nerves are necessary.
79
80 15 Facial Mesotherapy

Fig. 15.1 Possible combinations

for facial mesotherapy: emulsion
(A), platelet-rich plasma (B),
vitamins (C)

Fig. 15.2 Example of one of the

most frequent distributions of
injection sites for facial
mesotherapy
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