NIACINAMIDE Coversheet for Certificate of Analysis Productcode : 0487848 Lot No. : 0P11801022 Analysis No. 03C76330 fC Number : 03410728 Articlecode : 0487848340 Sales Name : NIACINAMIDA, 20 KG CARTON ‘Manufacturing Date: 28-JAN-2018 Best Use Before Date : 27-JAN-2021 Delivery Note No. 1122843756 Destination : Colombia Customer Ref. No: 4500460907 Customer Article No: 0487848340 Customer Name: DSM Nutritional Products Colombia S.A, BOGOTA, D.C. Comment DS Nutritional Products Led Technical Deparment 4.402 Bae, Switzer Date of isu: 20-mar-0%8@osm NIACINAMIDE CERTIFICATE OF ANALYSIS Productcode : 0487848 LotNe. — : OP11801022 Analysis No. : 03C76330 Test Rosult Limits 1 Dimension Specifications 1 Units ‘Appearance crystalline powder crystalline powder visual Colour white white visual Assay 997 990 to 101.0 % ww HPLC Related Substances: Nicotinic acis <0.05 max. 0.10 % ww HPLC ‘Seyanopyridine <0.05 max. 0.10 %wiw HPLC ‘Any unknown impurity <0.05 max. 0.10 ww HPLC Total impurity 0.1 max. 02 eww HPLC PH of solution 66 60 0 75 Ph.Eur. of Nicotinamide Clarity of solution 02 max. 3.00 ntu Ph.Eur. of Nicotinamide Colour values (CIELAB) L* 100.0 90.0 to 101.0 Colour instrument Measurement Colour values (CIELAB) a* 00 “10.0 to 10.0 Colour instrument Measurement Colour values (CIELAB) bt 02 -10.0 to 10.0 Colour instrument Measurement Colour of solution (cale./BY) 7 min. 7 Ph.Eur. ef Nicotinamide Loss on drying 00 max. 05 % ww USP of Niacinamide ‘molting range start.point 1289 1280 to 131.0 e Ph.Eur, of Nicotinamide ‘melting range end.point 1284 128.0 to 131.0 Ph.Eur. of Nicotinamide Particle Size Fraction min. 50 um 100 min, 90.0 mw sieve analysis ‘min. 250 um 5 max. 80 win sieve analysis Sulphated ash 0.06 max. 0.10 % ww Ph Eur of Nicotinamide DSM Nutritional Products Lia 112 Date ofissve 2 Maraote Branch Sin Scsaln@osm NIACINAMIDE CERTIFICATE OF ANALYSIS Producteode : 0487848 Lot No. : OP11801022 Analysis No. : 03C76330 Te Result Limits 7 Dimension Specifications 1 Units: Heavy Metals 20 max. 20 ppm USP (method Il) of Niacinamide Chloride <0 max. 70 moka Limit test JP ‘Sulfate <190 max. 190 mo/kg Limit test JP Readily carbonizable substances passes test passes test USP of Niacinamide Identification corresponds: ‘corresponds UV, USP of Niacinamide Identification corresponds corresponds NaOH, JP of Niacinamide Identification ‘corresponds corresponds IR, EPIUSP of Niacinamide Loss on drying 00 max. 05 Ye wiw Ph. Eur. of Niacinamide Lead corresponds* max. 2 pom USP <730> *) checked at regular intervals ‘This lot was analysed and re specifications as given above, ‘The product meats all requirements ofthe folowing vald compendia when tested accordingly USP,FCC,Ph Eur. sed by our authorized Quality Control Department and was found to meet the DSM Nutritional Products Lia ‘The Quality Assurance Manager pracbrea bracket Kreutzer Andrea ‘DSM Nutitional Products Lia 22 ‘te otwsue O2AMar 218 in te Seon