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Oral Rehydration Salts (ORS)

Overview
Oral redyration salt is used for oral replacement of electrolytes
and fluids in patient with dehydration associated with diarrohea.
The main constitutes oral rehydration salt are anhydrous
dextrose, sodium chloride, potassium chloride and either
trisodium citrate dihydrate or sodium bicarbonate. The simple
glucose electrolyte solutions can adequately rehydrate patients.
Oral Rehydration Salts is one of the major therapeutic advances
of this century and since 1960s it has saved the lives of millions of
children. It has become the manistay of treatment for the
dehydration and acidosis associated with acute infectious
diarrohea.
Categories
17 Gastrointestinal drugs
17.7 Drugs used in diarrhea
17.7.1 Oral rehydration
26 Hospital fluids
26.1 Oral solutions
26.1.1 Oral rehydration salt (ORS)
Page headings
Overview Primary Characterstics Indications
Pharmacokinetics Contraindications Drug Interactions
Side Effects Dosage High Risk Groups Warning /
Precautions Storage Conditions Interference in Pathology
Brands of Oral Rehydration Salts (ORS) Manufacturers of Oral
Search Rehydration Salts (ORS)
Suggested Pages
Primary Characterstics
Oral Rehydration Salts (ORS) also known as ORS. Oral
Rehydration Salts (ORS) also known as ORS. It is of Synthetic
origin and belongs to Salts. It belongs to Nutrients and Vitamins
pharmacological group on the basis of mechanism of action
and also classified in Electrolyte Oral pharmacological group.
Indications
Oral Rehydration Salts (ORS) is primarily indicated in conditions
like Acute infectious diarrhoea, Dehydration, Diarrhoea, Fluid and
electrolyte loss in diarrhoea, Fluid depletion, Rehydration of
patient with burns.
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 patient with burns.
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Oral Rehydration Salts (ORS) is contraindicated in conditions like Monograph
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Side Effects
The severe or irreversible adverse effects of Oral Rehydration Salts
(ORS), which give rise to further complications include
Radiosensitization effect on thorax, Skin inflammation,
Esophageal inflammation.
Oral Rehydration Salts (ORS) produces potentially life-
threatening effects which include Hyperkalemia, Hyperkalemia,
Hypernatremia. which are responsible for the discontinuation of
Search DrugInfoSys Oral Rehydration Salts (ORS) therapy.
Drugs The signs and symptoms that are produced after the acute
Search overdosage of Oral Rehydration Salts (ORS) include Severe
vomiting, Mucositis, Diarrhea, Severe myelosuppression,
Search Hyperkalemia, Hypernatremia.
The symptomatic adverse reactions produced by Oral
Rehydration Salts (ORS) are more or less tolerable and if they
become severe, they can be treated symptomatically, these
include Nausea, Vomiting, Alopecia, Diarrhea, Mucositis, Fever,
Myalgia, Abdominal pain, Reaction at injection site, Alopecia.
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Dosage
Oral Rehydration Salts (ORS)'s dosage details are as follows:
Dose Single Dose Frequency Route Instructions
Sign in or Sign up Adult Dosage
200 to 400 ml 300 (300) As PO During 24 hrs.,
User ID recommended. As required
Password Paedriatic Dosage (20kg)
Sign in 0.028 to 0.057 0.042 (0.0425) As Oral During 24 hrs.,
Remember me - forgot password Litrtes/kg recommended. As required
Neonatal Dosage (3kg)

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0.028 to 0.057 0.042 (0.0425) As Oral During 24 hrs.,
Litrtes/kg recommended. As required

High Risk Groups

Drug should not be given to patients suffering from Kidney
dysfunction, and Neonates.

If prescribing authority justifies the benefits of the drug against

the possible damages he/she should reevaluate them and
consult the reference material and previous studies.
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Warning / Precautions
Use with caution in patients with pre-existing blood
disorders, gout, dental disease, liver disease or heart disease.
This medication is classi ed as pregnancy category C and
should be used during pregnancy or lactation only if clearly
needed. These are not appropiate for patients with
gartrointestinal obstruction, oliguric or anuric renal failure
oral rehydration salts should be reconstituted only with
water.

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Storage Conditions
Solution, Syrup, Powder

Store in a well closed container, at room temperature.

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Interference in Pathology
Bioassay procedures for determination of antibacterial drug
levels.
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Brands / Trade Names of Oral

Rehydration Salts (ORS)
No Brands Available.
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Manufacturers of Oral Rehydration Salts
(ORS) in Pakistan
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