BIOMATERIALS

IBIO 2650
2018-1
Instructors: Juan C. Cruz
Carolina Muñoz
Graduate Assistants:
Paula Guerrero, Alejandra Suárez
Undergrad. Assistants: Laura Bocanegra
 Course Methodology

• Interactive lecture style format.

• Quizzes every Friday starting on the second week
• Laboratories
• Paper discussions and presentations
• Exams will be given in class consisting of short
answer and essay questions and will be closed book.
 The Lab Experience

• Lab protocols –SICUA

• Safety lecture during the first week
• All laboratory assignments and reports will be
submitted to the TA via SICUA a week after the
practice
• Format for lab reports will be discussed by GAs
 Lab Topics
Lab 1 – Safety
Lab 2 – Hydrogels
Lab 3 – Characterization of Hydrogels
Lab 4 – Chemical and enzymatic degradation
Lab 5 – Platelet aggregation
Lab 6 – Microscopic Characterization
Lab 7 – Spectroscopic and thermal Characterization
Lab 8 – Mechanical characterization
Lab 9 – Nanomaterials
 Syllabus
Introduction
Polymers and applications
Degradable Materials
Microscopic characterization
Metals and applications
Ceramic materials and applications
Spectroscopic characterization
Thermal, Mechanical and Electrical characterization
Immunology and foreign body response
Sterilization and Implant Associated Infections
Biological Testing
Composites and Nanomaterials
 Grading

Activity Details Amount Percentage

Midterms Comprehensive. 2 30
Weeks 6 and 12
Assignments and N.D 15
Quizzes
Labs 9 15
Projects Reports 3 5
Final report and 1 10
presentation: Week 16
Final Exam Comprehensive 1 15
TOTAL 100
 Undergraduate Project

Design and testing of a biomaterial to address one of

the following challenges
• Teeth fragile enamel of children
• Granulomas derived from silicone injections
• Drug release system for colon diseases
• Rapid detection devices of pathogens
 Undergraduate Project
Timeline
• Meeting with Graduate Assistants (Week 4-5)
• First report (video) (Week 5)
• Second report (Week 8)
• Third report (Week 13)
• Final Report (Week 16)
https://www.youtube.com/watch?v=RPCNOSBB91U
https://www.youtube.com/watch?v=Y0b0HUG8NTA
 Homework #1
1. Briefly describe 3 emerging applications of biomaterials
Discuss how to implement these applications in the
Colombian healthcare marketplace. What are the main
barriers for entrance?
2. Make an estimate of how many different types of
biomaterials are in use today? Hint: Explore FDA regulation
on biomedical devices
3. Find the definition of Biomaterial by the FDA, explain it in
your own words and explain its implications for new
biomaterials
 Biomaterial or Medical Device ?
• FDA neither approves materials nor maintains a list of
approved materials
• The properties and safety of materials must be carefully
assessed with respect to the specific application in question
and its degree of patient contact.
• The final assessment must be performed on the finished
product, under actual use conditions.