ABSTRAC

It has been that the mineral trioxide aggregate (MTA) used to seal lateral/furcal perforations
stimulates the deposition of newly formed cementun. Nevertheles, when the site of the
perforation is contaminated, the healing process might occur under less favorable conditions. This
study evaluated the repair healing process of noncontaminated and contaminated lateral
perforations filled with MTA and the effect of previously filling the contaminated perforations with
a bactericidal agent. Thirty lateral root perforations were prepared in endodontically treated dogs
teeth, thus forming 3 groups with 10 specimens each. In group 1 the perforations were
immediately seales with MTA in group 2 the perforations were left open for 7 days and thereafter
sealed with MTA.in group 3 the perforations were left open for 7 days, filledtemporarily with a
calcium hydroxide-based paste for 14days, and then sealed with MTA. The animals were killed
after 90 days, and the pieces were prepared for histomorphologic and histomicrobiologic
evaluations. The statistical analysis showed that group 1 had significantly better repair than group
1 had significantly better repair than groups 2 (p <.05) and 3 (p <.05), which validates the superior
results obtained when MTA was immediately used to seal root perforations. Groups 2 and 3 had
statistically similar repair to each other (p >.05) there were a larger number of cases of complete
or partial biologic seal in group 1 compared with the contaminated groups. It might be concluded
that the lateral root perforations sealed with MTA after contamination presented worse repair
than the noncontaminated, immediately sealed perforations. The temporary filling with a
bactericidal agent (calcium hydroxide- based paste) did not improve the repair of perforations
exposed to contamination, and the contaminated groups presented similar results to each other.

Resumen

Se ha sido que el agregado de trixido mineral (MTA) que se utiliza para sellar perforaciones
laterales / furcales estimula la deposicin de cementun recin formado. Nevertheles, cuando el
sitio de la perforacin est contaminado, el proceso de curacin puede ocurrir bajo condiciones
menos favorables. Este estudio evalu el proceso de curacin de reparacin de perforaciones
laterales no contaminadas y contaminadas llenos de MTA y el efecto de llenar previamente las
perforaciones contaminados con un agente bactericida. Treinta perforaciones radiculares laterales
se prepararon en los dientes del perro tratado endodnticamente, formando as 3 grupos con 10
ejemplares cada uno. En el grupo 1 de las perforaciones fueron inmediatamente Seales con MTA
en el grupo 2 de las perforaciones se dejaron abiertas durante 7 das y posteriormente sellados
con el grupo MTA.in 3 de las perforaciones se dejaron abiertas durante 7 das, filledtemporarily
con una pasta a base de hidrxido de calcio de 14 das, y luego sellado con MTA. Los animales
fueron sacrificados despus de 90 das, y las piezas se prepararon para las evaluaciones
histomorfolgicas y histomicrobiologic. El anlisis estadstico mostr que el grupo 1 tuvieron
significativamente mejor estado que el grupo 1 tuvo significativamente mejor estado que los
grupos 2 (p <0,05) y 3 (p <0,05), lo que valida los resultados superiores obtenidos cuando
inmediatamente se utiliz MTA para sellar la raz perforaciones. Grupos 2 y 3 tuvieron reparacin
estadsticamente similares entre s (p> 0,05) hubo un mayor nmero de casos de sellado biolgico
completo o parcial en el grupo 1 en comparacin con los grupos contaminados. Podra concluirse
que las perforaciones radiculares laterales sellados con MTA despus de la contaminacin
presentan peor de reparacin de las perforaciones no contaminadas, inmediatamente sellados. El
relleno temporal con un agente bactericida (hydroxide- pasta a base de calcio) no mejor la
reparacin de perforaciones expuestas a la contaminacin, y los grupos contaminados present
resultados similares el uno al otro.