pinot Revised elagnstc criteria for neuromyelitisopica Home | Currentisaue _Alllesues Ahead of Print Neurology ‘nea a ho tex ao rg 10.121201 wt. 0000216198.44758.74 Nowriogy Mey 23, 2008 el. 85 no. 10 485-489 ® Check for updates | antl Revised diagnostic criteria for neuromyelitis optica LM. Wingerehak MD, FRCP(C), VA. Lenon.MD, PR, SJ Petack, MO,C.F Lucci, MD and 8.6 Wana MD, FREPIC) rp rama Ort Non eh np x doierg0 12°20 wt 0000218180 44250.74 Flext || Fu Text POF) Auccvaibhe Ona Sion ABSTRACT Background: The suber prevously proposed dlogostc ete fr rauranyelisopica (AMO) thal fcitate te dstncton fom peatype mutiple slaosls (US). However, some paints wth otnerwse typical NNO have asstoral symptoms not atbuzats to optic nerve or spinal cor ivlarmaton or havo MSko bran MRL lesions. Futbemoe, some paints are mcissfed at NNO by te autor” eaarpropoted err coup having 2 subsequent couse Indstrgusnable rom poatype MS. A serum autcarbogy marker, NMO%9G, ley specie for NMO. Th authors propse ised NMO dagnostic itera hat ncorporte NMOW9G statis Methods: Using al elncal gros (NMO or MS) a the rferance sansa, the alors eau sesitty and spectfey fr each efteion and varaus cambination using 8 sane of SE pater wth NUO and 33 with MS. “ho authors usod tkelnoed relos and lste epesson analysis to dovelop the mest preccal and ifomative Adagroste mod. Results: Fouren paints wth NMO (14.5%) hat exsapespnal CNS eynploms. NVOIEG apositivly wae "75% senstive ana 94% spoecc for NMO. The best cagnestc combination wae 9% sorstve and 0% specie for INMO and consstos of at last two of tres slomerts: lengua extensive cor lesion, onset ran MRI rnordagrotc fr MS, oe NMO.gG Soop. Conclusions: The authrs propose revises dapratc ctata for dette newonyatis oxic (NNO) tht equre otc nour, myelis, an at ast woof tee suppotve crt: NR eidence ot conéguus spinal cor Iesion 3 ‘oF more segments in length, arse! brain MRI rendagnests for mull sclera, oF NMOIGG seropssivily. CNS Invlvamen beyend the ope nerves and spina cori compat wit NO. RELATED ARTICLES tap shwwra neurology. orglcontent66/1011485 short ctl teat | tack? ome ‘About the Joumel 12pinot Revised clagnost criteria for neuemyelit ‘The lumping and spliting ofiftammatory CNS diseases ‘Sep Foe FullText Ful eat POF) [Neuromyelits optica diagnosis in clinically folated syndromes suggestive of multiple selerosis Ny 2,798 1 15S Mok 112201 wn ECT CDO SE 2 AEX sract Fulltext (PDF) Flutes Ony Neurology asses, $B @votestine Sri cen ‘eoncom igre ‘en Amarr Acne aausby Ab | Fwsack | Maven tap shwwra neurology. orglcontent66/1011485 shart