Shaq-Actin a fool

By Emma, Justin, Alexa, Zach

Where found/ Function

Cytoskeleton of an animal cell
Function: helps muscle contraction

Organelles
Mitochondria
Lysosomes
Ribosomes

DNA to Protein Process

Transcription
RNA polymerase, an enzyme, unwinds the DNA.
Ribonucleotide Triphosphates (NTPs) bond with the antisense
strand of DNA (the helix that is not the coding gene. The coding
gene is called the sense strand), meaning that the watson-crick
base pairs (ATCG) of the
RNA Polymerase duplicates the antisense strand until it
encounters a stop signal contained within the DNA, the result is
mRNA identical to the sense strand, which gets sent to a
ribosome.
This process occurs in the nucleus of a cell (if eukaryotic)

Translation
mRNA enters a ribosome, which is an organelle floating in
the cytoplasm, where tRNA is free-floating
tRNA, which is attached to an amino acid, approaches the
mRNA strand
The codons of the mRNA (which is composed of 3 bases)
matches the anticodon on tRNA (also 3 bases)
The tRNA releases its amino acid, which quickly bonds
with other amino acids nearby to form a peptide strand
Happens in the cytoplasm and ribosome

Folding
A chaperonin (TCP-1) folds the amino acid chain in order for
the amino acid to become useful for the organism
The folding happens in 4 steps:
1.
2.
3.
4.

Primary- amino acid chains join together

Secondary- amino acid chains fold into sheets/ coils
Tertiary- sheets/ coils fold into each other
Quaternary- chains fold into specific structure

DNA Sequence
ACCTGACAACCTCTCATCCCTGCTCTGCAGATCCGGTCCCATCCCCACTGCCCACCCCACCCCCCCAGCACTCCACCCAGTTCAACGTTCCACGAACCCCCAGAA
CCAGCCCTCATCAACAGGCAGCAAGAAGGGCCCCCCGCCCATCGCCCCACAACGCCAGCCGGGTGAACTGTAGCGTTGGCAGGTCCTGAGGCAGCTGGCAAGA
CGCCTGCAGCTGAAAGATACAAGGCCAGGGACAGGACAGTCCCATCCCCAGGAGGCAGGGAGTATACAGGCTGGGGAAGTTTGCCCTTGCGTGGGGTGGTGA
TGGAGGAGGCTCAGCAAGTCTTCTGGACTGTGAACCTGTGTCTGCCACTGTGTGCTGGGTGGTGGTCATCTTTCCCACCAGGCTGTGGCCTCTGCAACCTTCAA
GGGAGGAGCAGGTCCCATTGGCTGAGCACAGCCTTGTACCGTGAACTGGAACAAGCAGCCTCCTTCCTGGCCACAGGTTCCATGTCCTTATATGGACTCATCTTT
GCCTATTGCGACACACACTCAGTGAACACCTACTACGCGCTGCAAAGAGCCCCGCAGGCCTGAGGTGCCCCCACCTCACCACTCTTCCTATTTTTGTGTAAAAAT
CCAGCTTCTTGTCACCACCTCCAAGGAGGGGGAGGAGGAGGAAGGCAGGTTCCTCTAGGCTGAGCCGAATGCCCCTCTGTGGTCCCACGCCACTGATCGCTGC
ATGCCCACCACCTGGGTACACACAGTCTGTGATTCCCGGAGCAGAACGGACCCTGCCCACCCGGTCTTGTGTGCTACTCAGTGGACAGACCCAAGGCAAGAAAG
GGTGACAAGGACAGGGTCTTCCCAGGCTGGCTTTGAGTTCCTAGCACCGCCCCGCCCCCAATCCTCTGTGGCACATGGAGTCTTGGTCCCCAGAGTCCCCCAGC
GGCCTCCAGATGGTCTGGGAGGGCAGTTCAGCTGTGGCTGCGCATAGCAGACATACAACGGACGGTGGGCCCAGACCCAGGCTGTGTAGACCCAGCCCCCCC
GCCCCGCAGTGCCTAGGTCACCCACTAACGCCCCAGGCCTTGTCTTGGCTGGGCGTGACTGTTACCCTCAAAAGCAGGCAGCTCCAGGGTAAAAGGTGCCCTGC
CCTGTAGAGCCCACCTTCCTTCCCAGGGCTGCGGCTGGGTAGGTTTGTAGCCTTCATCACGGGCCACCTCCAGCCACTGGACCGCTGGCCCCTGCCCTGTCCTG
GGGAGTGTGGTCCTGCGACTTCTAAGTGGCCGCAAGCCACCTGACTCCCCCAACACCACACTCTACCTCTCAAGCCCAGGTCTCTCCCTAGTGACCCACCCAGC
ACATTTAGCTAGCTGAGCCCCACAGCCAGAGGTCCTCAGGCCCTGCTTTCAGGGCAGTTGCTCTGAAGTCGGCAAGGGGGAGTGACTGCCTGGCCACTCCATGC
CCTCCAAGAGCTCCTTCTGCAGGAGCGTACAGAACCCAGGGCCCTGGCACCCGTGCAGACCCTGGCCCACCCCACCTGGGCGCTCAGTGCCCAAGAGATGTCC
ACACCTAGGATGTCCCGCGGTGGGTGGGGGGCCCGAGAGACGGGCAGGCCGGGGGCAGGCCTGGCCATGCGGGGCCGAACCGGGCACTGCCCAGCGTGGG
GCGCGGGGGCCACGGCGCGCGCCCCCAGCCCCCGGGCCCAGCACCCCAAGGCGGCCAACGCCAAAACTCTCCCTCCTCCTCTTCCTCAATCTCGCTCTCGCTC
TTTTTTTTTTTCGCAAAAGGAGGGGAGAGGGGGTAAAAAAATGCTGCACTGTGCGGCGAAGCCGGTGAGTGAGCGGCGCGGGGCCAATCAGCGTGCGCCGTTC
CGAAAGTTGCCTTTTATGGCTCGAGCGGCCGCGGCGGCGCCCTATAAAACCCAGCGGCGCGACGCGCCACCACCGCCGAGACCGCGTCCGCCCCGCGAGCAC
AGAGCCTCGCCTTTGCCGATCCGCCGCCCGTCCACACCCGCCGCCAGGTAAGCCCGGCCAGCCGACCGGGGCAGGCGGCTCACGGCCCGGCCGCAGGCGGCC
GCGGCCCCTTCGCCCGTGCAGAGCCGCCGTCCCCAGTGTGACATGGTGTATCTCTGCCTTACAGATCATGTTTGAGACCTTCAACACCCCAGCCATGTA ...

Actin 3D
model