ACADEMIC REGULATIONS, COURSE STRUCTURE

AND DETAILED SYLLABUS

M. Pharm (HOSPITAL AND CLINICAL PHARMACY)

FOR
MASTER PHARMACY TWO YEAR POST GRADUATE COURSE
(Applicable for the batches admitted from 2012-2013)

ANURAG GROUP OF INSTITUTIONS

(AUTONOMOUS)
SCHOOL OF PHARMACY
Venkatapur, Ghatkesar, Hyderabad 500088

2012-2013

Academic Regulations for M. Pharm (Regular) Degree Course

(Effective for the students admitted into I year from the Academic Year 2012-2013 onwards)

The M.Pharm Degree of Jawaharlal Nehru Technological University

Hyderabad shall be conferred on candidates who are admitted to the program
and fulfill all the requirements for the award of the degree.
1.0ELIGIBILITY FOR ADMISSIONS:
Admission to the above program shall be made subject to the eligibility,
qualifications and specialization prescribed by the university from time to
time.
Admissions shall be made on the basis of merit rank obtained by the
qualifying candidate at an Entrance Test conducted by the University or on
the basis of any other order of merit approved by the University, subject to
reservations prescribed by the university from time to time.
2.0AWARD OF M.PHARM DEGREE:
2.1A student shall be declared eligible for the award of the M.Pharm degree,
if he pursues a course of study and completes it successfully for not less
than two academic years and not more than four academic years.
2.2A Student, who fails to fulfil all the academic requirements for the award
of the degree within four academic years from the year of his admission,
shall forfeit his seat in M.Pharm course.
2.3The minimum instruction period for each semester is 90 clear instruction
days.
3.0 COURSE OF STUDY
The following specializations are offered at present for the M.Pharm
Course of study.
1. Hospital and Clinical Pharmacy
2. Pharmaceutics
3. Industrial Pharmacy
4. Pharmacology
5. Pharmaceutical Analysis and Quality Assurance
4.0 ATTENDANCE:
The programs are offered on a unit basis with each subject being
considered as an unit.
4.1A candidate shall be deemed to have eligibility to write end semester
examinations in a subject if he has put in at least 75% of attendance in the
subject.

2012-2013

4.2Shortage of attendance up to 10% in any subject (i.e. 65% and above and
below 75%) may be condoned by the college Academic council on
genuine and valid reasons on representation by the candidate with
supporting evidence.
4.3A candidate shall get minimum required attendance at least in three (3)
theory subjects in the present semester to get promoted to the next
semester. In order to qualify for the award of the M.Pharm Degree, The
candidate shall complete all the academic requirements of the subjects, as
per the course structure.
4.4 Shortage of attendance below 65% shall in no case be condoned
4.5 A stipulated fee shall be payable towards condonation of shortage of
attendance.
5.0 EVALUATION:
The performance of the candidate in each semester shall be evaluated
subject-wise, with a maximum of 100 marks for theory and 100 marks for
practicals, on the basis of internal evaluation and End semester Examination.
For the theory subjects 60 marks shall be awarded based on the performance
in the End semester Examination, 30 marks shall be awarded based on the
internal evaluation and 10 marks for assignment.
5.1For theory subjects, during the semester there shall be 2 midterm
examinations. Each midterm examination consists of one subjective paper
and one assignment. The subjective paper is for 30 marks with duration of 2
hours. Subjective paper of each semester shall contain 2 parts Section-A &
Section-B. Section-A comprises of five (5) short answer type of questions.
The student has to answer all the questions from section-A. Each question
carries two marks. A total of ten marks are allocated to section-A. SectionB consists of five (5) essay type of questions from which the student has to
answer three questions. Each question carry not more than seven (7) marks.
A total of 20 marks are allocated for section-B. The questions in the first
midterm examination includes the topics of first 2.5 units while the
questions in the second midterm examination includes the topics of
remaining 2.5 units. The assignments should be submitted before the
conduct of respective midterm examinations.
The total marks secured by the student are out of 40 marks (30marks from
midterm examination and 10 marks from assignment) in an internal
examination for a subject. The average of marks secured in two midterm
examinations shall be taken as final marks. If he/she is absent for any test /
assignment, he/she are awarded zero marks for that test / assignment.
5.2For practical subjects, 60 marks shall be awarded based on the performance
in the End Semester Examinations, 40 marks shall be awarded based on the
day-to-day performance as internal marks.

2012-2013

5.3There shall be two seminar presentations during I year I semester and II

Semester. For seminar, a student under the supervision of a faculty member,
shall collect the literature on a topic and critically review the literature and
submit it to the department in a report from and shall make an oral
presentation before the departmental committee. The departmental
committee consists of Head of the department, supervisor and two other
senior faculty members of the department. For each seminar there will be
only internal evaluation of 50 marks. A candidate has to secure a minimum
of 50% to be declared successful.
5.4There shall be a Comprehensive Viva-Voce in II year I Semester. The
comprehensive Viva-Voce will be conducted by a committee consisting of
Head of the Department and two Senior Faculty members of the
Department. The comprehensive Viva-Voce is aimed to assess the students
understanding in various subjects he/she studies during the M.Pharm course
of study. The Comprehensive viva-voce valued for 100 marks by the
Committee. There are no internal marks for the Comprehensive viva-Voce
5.5 A candidate shall be deemed to have secured the minimum academic
requirement in a subject if he secures a minimum of 40% of marks in the
End Examination and a minimum aggregate of 50% of the total marks in
the End Semester Examination and Internal Evaluation taken together.
5.6In case the candidate does not secure the minimum academic requirement in
any subject (as specified in 4.3) he has to reappear for the End Examination
in that subject. A candidate shall be given one chance to re-register for each
subject provided the internal marks secured by a candidate are less than
50% and he has failed in the end examination. In such case candidate must
re-register subject(s) and secure required minimum attendance. Attendance
in the re-registered subject(s) has to be calculated separately to become
eligible to write the end examination in the re-registered subject(s). The
attendance of re-registered subject(s) shall be calculated separately to
decide upon the eligibility for writing the end examination in those
subject(s). In the event of taking another chance, the internal marks and end
examination marks obtained in the previous attempt are nullified.
5.7In case the candidate secures less than the required attendance in any
subject(s), he shall not be permitted to appear for the End Examination in
that subject(s). He shall re-register the subject when next offered.
5.8 Laboratory examination for M.Pharm courses must be conducted with two
Examiners, one of them being Laboratory Class Teacher and second
examiner shall be other Laboratory Teacher.

2012-2013

6.0 EVALUATION OF PROJECT /DISSERTATION WORK:

Every candidate shall be required to submit thesis or dissertation after
taking up a topic approved by the project review committee.
6.1A Project Review Committee (PRC) shall be constituted with Principal as
chair person, Heads of all the departments which are offering the M.Pharm
programs and two other senior faculty members.
6.2Registration of Project work: A candidate is permitted to register for the
project work after satisfying the attendance requirement of all the subjects
(theory and practical subjects).
6.3After satisfying 6.2, a candidate has to submit, in consultation with his
project supervisor, the title, objective and plan of action of his project
work to the Departmental Committee for its approval. Only after obtaining
the approval of Departmental Committee the student can initiate the
Project work.
6.4If a candidate wishes to change his supervisor or topic of the project he
can do so with the approval of Departmental Committee. However, the
Departmental Committee shall examine whether the change of
topic/supervisor leads to a major change of his initial plans of project
proposal. If so, his date of registration for the project work starts from the
date of change of Supervisor or topic as the case may be.
6.5A candidate shall submit status report (in a bound-form) in two stages at
least with a gap of 3 months between them.
6.6The work on the project shall be initiated in the beginning of the second
year and the duration of the project is for two semesters. A candidate is
permitted to submit project thesis only after successful completion of
theory and practical course with the approval of PRC not earlier than 40
weeks from the date of registration of the project work. For the approval of
PRC the candidate shall submit the draft copy of thesis to the Principal
(through Head of the Department) and shall make an oral presentation
before the PRC.
6.7Three copies of the Project Thesis certified by the supervisor shall be
submitted to the College/School/Institute.
6.8The thesis shall be adjudicated by one examiner selected by the Institution.
For this, Chairmen, BOS of the respective departments shall submit a
panel of 5 examiners, who are eminent in that field with the help of the
concerned guide and senior faculty of the department.
6.9If the report of the examiner is not favourable, the candidate shall revise
and resubmit the thesis, in the time frame as prescribed by PRC. If the
report of the examiner is unfavourable again the thesis shall be summarily
rejected.

2012-2013

6.10 If the report of the examiner is favourable, viva-voce examination shall

be conducted by a board consisting of the supervisor, Head of the
Department and the examiner who adjudicated the Thesis.
The Board shall jointly report candidates work as:
A. EXCELLENT
B. GOOD
C. SATISFACTORY
D. UNSATISFACTORY
Head of the Department shall coordinate and make arrangements for the
conduct of viva-voce examination. If the report of the viva-voce is
unsatisfactory, the candidate will retake the viva-voce examination after three
months. If he fails to get a satisfactory report at the second viva-voce
examination, he will not be eligible for the award of the degree.
7.0 AWARD OF DEGREE AND CLASS
After a student has satisfied the requirement prescribed for the completion of
the program and is eligible for the award of M.Pharm Degree he shall be
placed in one of the following three classes.
Classes Awarded
First Class with Distinction
First Class
Second Class

% of marks to be secured
70% and above
Below 70% but not less than 60%
Below 60% but not less than 50%

(The marks in internal evaluation and end examination shall be shown separately in the
marks memorandum)

8.0 WITH-HOLDING OF RESULTS:

If the candidate has not paid any dues to the institution or if any case of indiscipline is pending against him, the result of the candidate will be withheld
and he will not be allowed into next higher semester. The issue of the degree
is liable to be withheld in such cases.

9.0 TRANSITORY REGULATIONS:

Candidate who have discontinued or have been detained for want of
attendance or who have failed after having undergone the course are eligible
for admission to the same or equivalent subjects as and when subjects are
offered, subject to 5.5 and 2.0

2012-2013

10.0 GENERAL:
10.1 The academic regulations should be read as a whole for purpose of any
interpretation.
10.2 In case of any doubt or ambiguity in the interpretation of the above
rules, the decision of the Academic Council is final.
10.3 The institution may change or amend the academic regulations and
syllabus at any time and the changes and amendments made shall be
applicable to all the students with effect from the date notified by the
institution.
10.4 Wherever the word he, him or his occur, it will also include she, her and
hers. There shall be no transfers within the constituent colleges of Jawaharlal
Nehru Technological University.

2012-2013

MALPRACTICES RULES
DISCIPLINARY ACTION FOR IMPROPER CONDUCT IN EXAMINATIONS

Nature of Malpractices/Improper
conduct
If the candidate:
1. (a) Possesses or keeps accessible in
examination hall, any paper, note
book, programmable calculators,
cell
phones,
pager,
palm,
computers or any other form of
material concerned with or related
to the subject of the examination
(theory or practical) in which he is
appearing but has not made use of
(material shall include any marks
on the body of the candidate which
can be used as an aid in the subject
of the examination)
(b)
Gives assistance or guidance or
receives it from any other
candidate orally or by any other
body language methods or
communicates through cell phones
with any candidate or persons in or
outside the exam hall in respect of
any matter.
2.
Has copied in the examination hall
from
any
paper,
book,
programmable calculators, palm
computers or any other form of
material relevant to the subject of
the examination (theory or
practical) in which the candidate is
appearing.

3.

Punishment

Expulsion from the examination hall and

cancellation of the performance in that
subject only

Expulsion from the examination hall and

cancellation of the performance in that
subject only of all the candidates involved.
In case of an outsider, he will be handed
over to the police and a case is registered
against him.

Expulsion from the examination hall and

cancellation of the performance in that
subject and all other subjects the candidates
has already appeared including practical
examinations and project work and shall
not be permitted to appear for the
remaining examinations of the subjects of
that semester/year. The hall ticket of the
candidate is to be cancelled and sent to the
controller of examinations, AGI.

Impersonates any other candidate The candidate who has impersonated shall
in
connection
with
the be expelled from examination hall. The
examination.
candidate is also debarred and forfeits the
seat. The performance of the original
candidate who has been impersonated,
shall be cancelled in all the subjects of the
examination(including practicals and
project work) already appeared and shall
not be allowed to appear for examinations

2012-2013

4.

Smuggles in the Answer book or

additional sheet or takes out or
arranges to send out the question
paper during the examination or
answer book or additional sheet,
during or after the examination.

5.

Uses objectionable, abusive or

offensive language in the answer
paper or in letters to the examiners
or writes to the examiner
requesting him to award pass
marks.
Refuses to obey the orders of the
Chief
Superintendent/AssistantSuperintendent/ any officer on duty
or
misbehaves
or
creates
disturbance of any kind in and
around the examination hall or
organizes a walk out or instigates
others to walk out, or threatens the
officer-in-charge or any person on
duty in or outside the examination
hall of any injury to his person or
to any office relations whether by
words, either spoken or written or
by
signs
or
by
visible
representation, assaults the officerin-charge, or any person on duty in

6.

of the remaining subjects of that

semester/year. The candidate is also
debarred for two consecutive semesters
from class work and all semester
examinations. The continuation of the
course by the candidate is subject to the
academic regulations in connection with
forfeiture of seat. If the imposter is an
outsider, he will be handed over to the
police and a case is registered against him.
Expulsion from the examination hall and
cancellation of the performance in that
subject and all other subjects the candidates
has already appeared including practical
examinations and project work and shall
not be permitted for the remaining
examinations of the subjects of that
semester/year. The candidate is also
debarred for two consecutive semesters
from class work and all semester
examinations. The continuation of the
course by the candidate is subject to the
academic regulations in connection with
forfeiture of seat.
Cancellation of the performance in that
subject.

In case of students of the college, they shall

be expelled from examination halls and
cancellation of their performance in that
subjects and all other subjects the
candidate(s) has (have) already appeared
and shall not be permitted to appear for the
remaining examinations of the subjects of
that semester/year. The candidates also are
debarred and forfeit their seats. In case of
outsiders. They will be handed over to the
police and a police case is registered
against them.

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7.

2012-2013

or outside the examination hall or

any of his relations, or indulges in
any other act of misconduct or
mischief which result in damage to
or destruction of property in the
examination hall or any part of the
college campus or engages in any
other act which in the opinion of
the officer on duty amounts to use
of unfair means or misconduct or
has the tendency to disrupt the
orderly conduct of the examination.
Leaves the exam hall taking away
answer script or intentionally tears
of the script or any part thereof
inside or outside the examination
hall.

8.

Posses any lethal weapon or

firearm in the examination hall.

9.

If student of the college, who is

not a candidate for the particular
examination or any person not
connected with college indulges in
any malpractice or improper
conduct mentioned in clause 6 to 8

Expulsion from the examination hall and

cancellation of performance in that subject
and all the other subjects the candidates has
already appeared including practical
examinations and project work and shall
not be permitted for the remaining
examinations of the subjects of that
semester/year. The candidate is also
debarred for two consecutive semesters
from class work and all semester
examinations. The continuation of the
course by the candidate is subject to the
academic regulation in connection with
forfeiture of seat.
Expulsion from the examination hall and
cancellation of performance in that subject
and all the other subjects the candidates has
already appeared including practical
examinations and project work and shall
not be permitted for the remaining
examinations of the subjects of that
semester/year. The candidate is also
debarred and forfeits the seat.
Student of the colleges expulsion from the
examination hall and cancellation of
performance in that subject and all the
other subjects the candidates has already
appeared including practical examinations
and project work and shall not be permitted
for the remaining examinations of the
subjects of that semester/year. The
candidate is also debarred and forfeiture the
seat.
Person(s) who do not belong to the

2012-2013

10.

Comes in a drunken condition to

the examination hall.

11.

Copying detected on the basis of

internal evidence, such as, during
valuation or during special
scrutiny.

12.

If any malpractice is detected

which is not covered in the above
clauses 1 to 11 shall be reported to
the Malpractices committee, AGI
for further action to award suitable
punishment.

11

College will be handed over to police and,

a police case will be registered against
them.
Expulsion from the examination hall and
cancellation of performance in that subject
and all the other subjects the candidates has
already appeared including practical
examinations and project work and shall
not be permitted for the remaining
examinations of the subjects of that
semester/year.
Cancellation of the performance in that
subject and all other subjects the candidate
has
appeared
including
practical
examinations and project work of the
semester/year examinations.

12

2012-2013

M. PHARM. (HOSPITAL AND CLINICAL PHARMACY)

COURSE STRUCTURE AND SYLLABUS
I YEAR I SEMESTER
Subject Group
Subject
Code
A41001 HCPT
Modern Pharmaceutical Analytical
Techniques
A41002 HCPT
Advanced
Biostatistics
and
Research Methods
A41012 HCPT
Pathophysiology
and
Applied
Pharmacotherapeutics - I
A41013 HCPT
Advanced Clinical Pharmacy
A41014 HCPT
Community
Patient
Care/Community Pharmacy
A41210 Lab
Pathophysiology
and
Applied
Pharmacotherapeutics I Lab
A41211 Lab
Advanced Clinical Pharmacy- Lab
A41212
Seminar
Total Credits (5 Theory + 2 Labs + Seminar)
II SEMESTER
Subject Group
Code
HCPT
A42001
A42002
A42012
A42013

HCPT
HCPT
HCPT

Credits

3
3

0
0

3
3

0
-

3
-

2
2
21

Credits

Intellectual Property Rights & Drug

Regulatory Affairs
Screening methods and clinical
research
Clinical Pharmacokinetics and
Therapeutic Drug Monitoring
Pathophysiology and Applied
Pharmacotherapeutics II

Subject

A42014

HCPT

Hospital Pharmacy

Lab

Pathophysiology and Applied

Pharmacotherapeutics II Lab

A42210

0
-

3
-

2
2
21

A42211
A42212

Hospital Pharmacy Lab

Seminar
Total Credits (5 Theory + 2 Labs + Seminar)
Lab

2012-2013

13

II YEAR I SEMESTER
Subject
Code
A43210
A43211
A43212

Group

Subject Name

P Credits

Comprehensive Viva
Project Seminar - I
Project Work
Total Credits

2
2
18
22

II YEAR II SEMESTER

Subject
Code
A44207
A44208

Group

Subject Name

Credits

Project Work
Project Seminar - II
Total Credits

0
0

0
0

20
2
22

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2012-2013

I Year I Sem. M.Pharmacy (HCP)

(A41001) MODERN PHARMACEUTICAL ANALYTICAL
TECHNIQUES

Unit I
a. Column Chromatography: Adsorption and partition, theory, preparation,
procedure and methods of detection
b. Thin Layer Chromatography: Theory, preparation, procedures, detection
of compounds
c. Paper Chromatography: Theory, different techniques employed, filter
papers used, qualitative and quantitative detection
d. Counter current extraction, solid phase extraction techniques, gel
filtration

Unit II
a. Gas chromatography: Introduction, fundamentals, instrumentation,
columns: preparation and operation, detection, dramatization.
b. HPLC: Principles and instrumentation, solvents and columns used,
detection and applications

Unit III
a. UV-Visible spectroscopy: Introduction, electromagnetic spectrum,
absorbance laws and limitations, instrumentation-design and working
principle, chromophore concept, auxochromes, Wood-Fisher rules for
calculating absorption maximum, applications of UV-Visible
spectroscopy
b. IR spectroscopy: Basic principles-Molecular vibrations, vibrational
frequency, factors influencing vibrational frequencies, sampling
techniques, instrumentation, interpretation of spectra, FT-IR, theory and
applications

Unit IV
Mass spectroscopy: Theory, ionization techniques: electron impact
ionization, chemical
ionization, field ionization, fast atom
bombardment, plasma desorption, fragmentation process: types of
fission, resolution, GC/MS, interpretation of spectra and applications
for identification and structure determination

2012-2013

15

Unit V
NMR: Theory, instrumentation, chemical shift, shielding and
deshielding effects, splitting of signals, spin-spin coupling, proton
exchange reactions, coupling constant(J), nuclear overhauser
effect(NOE), 13C NMR spectra and its applications, 2D-NMR, COSY
and applications in pharmacy
Text Books:
1. Sharma BK (2007). Instrumental Methods of Chemical Analysis. 16th
ed. Delhi: Goel Publishing House.
2. Sharma YR (2011). Organic spectroscopy. 4th ed. New Delhi: S.Chand
& Co.
3. Connors KA (2010). A Text book of Pharmaceutical Analysis. 3rd ed.
India: Wiley India .
4. Vogel AI (2009). Text book of Quantitative Chemical Analysis. 6th ed.
Delhi: Pearson.
5. Beckeet AH (2002). Stenlake J.B Practical Pharmaceutical Chemistry .
4th ed. New Delhi: CBS Publication.
6. Finar IL (2009). Organic Chemistry. 6th ed. New Delhi: Pearson.
7. William Kemp (2005). Organic Spectroscopy. New York: Palgrave.
8. Grrett DC (2007). Quantitative Analysis of Drugs. 3rd ed. New Delhi:
CBS Publishers.
9. Sethi PD (2010). Quantitative Analysis of Drugs in Pharmaceutical
Formulations . 3rd ed. New Delhi: CBS Publishers.
10.Silverstein (2010). Spectrophotometric identification of Organic
Compounds . 6th ed. New Delhi: John Wiley.
11.Seth PD (1996). HPTLC: High Performance Thin Layer
Chromatography. New Delhi: CBS publishers.
12.India. Ministry of Health and Family Welfare, Indian Pharmacopoeia
Commission (2007). Indian Pharmacopoeia. Ghazibad (Raj Nagar):
Indian Pharmacopoeia Commission.

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2012-2013

I Year I Sem. M.Pharmacy (HCP)

(A41002)ADVANCED BIOSTATISTICS AND RESEARCH
METHODS
Unit-I :
Developing a research question, Resources for research question,
Literature Review: Traditional Qualitative Review
Meta-AnalysisA Quantitative Review
Preparation of Research Proposal
VariablesDefinition of Variable, Types of variablesDependent and
Independent variables, Confounded variables, Measurement of variables,
Types of measurement scales and their comparison. Reliability and Validity of
Measurements.
Unit-II :
Validity, Types of validityInternal validity, Construct validity, External
validity, Threats to validity.
Control: Subject as own control (Within Subject control), Statistical control.
Unit-III:
Non-experimental Research:
Part 1Observational, Archival and Case-Study Research: The Hermeneutic
Approach.
Observational Research: Naturalistic Observation, Participant-Observer
Research.
Archival Research: Archival Data Collection and Compilation.
Case Studies: Characteristic of Case Studies.
Non-experimental Research: Survey ResearchDesigning of Questionnaire,
Methods of Administration, Response Rates. Types of SamplesHaphazard
Samples, Purposive Samples, Convenience Samples and Probability Samples.
Unit-IV :
True Experiments: Single-Factor Designs, Factors, Levels, Conditions, and
Treatments. Within-Subject Designs.
True Experiments Part-2Factorial DesignsMain Effects, Interactions, A
Mixed Factorial Design.
Unit V :
Single-Subject Experiments: Advantages and Disadvantages.
Quasi Experiments: The differences between Quasi and True Experiments.
Design without Control GroupsInterrupted Time Series Designs and
Repeated Treatment Designs.

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17

Text Books
1. Donald H. Mc Burney -Theresa L. White (2009). Research Methods. New
Delhi: Cengage learning India Pvt. Ltd.
2. Hooda-R.P (2000). Statistics for business and economics. 3rd ed. New
Delhi: MC. Millan Business books.
3. Tiwar N.K.,Rao G.N (2008). Biostatistics & Computer applications.
Sultan Bazar, Hyderabad, AP: Pharma Med Press.
4. Lippincot Williams (2006). Remingtons Pharmaceutical Sciences. 21st ed.
Noida, India: B.I. Publications.
5. Leon Lachman, Herbert A. Lieberman (2009):The Theory and Practice
of industrial Pharmacy ,2 nd ed, New Delhi:CBS Publishers
and Distributors.

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2012-2013

I Year I Sem. M.Pharmacy (HCP)

(A41012) PATHOPHYSIOLOGY AND APPLIED
PHARMACOTHERAPEUTICS I
Pathophysiology and applied Pharmacotherapeutics of diseases associated
with following system/diseases with of special reference to the drug of choice.
Unit-I Cardiovascular
Acute Coronary Syndrome
Hypertension
Congestive Cardiac Failure
Ischaemic Heart Disease (Angina Pectoris, Myocardial
Infarction)
Arrythmias
Hyperlipidarmia
Cardiopulmonary Arrest
Shock
Cardiomyopathy
Unit-II Respiratory System
Introduction to pulmonary function tests
Asthma
Chronic Obstructive Pulmonary Disease
Drug Induced Pulmonary Diseases
Hydrogen Ion Hemostasis & Blood Gases(external and
internal respiration).
Unit-III Haematological Diseases & Nephrology
Anaemias
Thalassemia
Drug Induced Haematological Diseases
Venous Thromboembolism
Acute Renal Failure / Chronic Renal Failure
Renal Dialysis and Transplantation
Drug Dosing In Renal Failure / Impairment
Drug Induced Renal Diseases
End-Stage Renal Disease
Diuretic Therapy
Potassium Depletion
Hyperkaelemia
Alakalosis

2012-2013

19

Unit-IV Gastroentrology & Rheumatology

Gastro Oesophageal Reflux Disease
Peptic Ulcer Disease
Inflammatory Bowel Disease
Hepatitis, Viral
Jaundice & Cirrhosis
Diarrhoea & Constipation
Drug Induced Liver Disease
Gout & Hyperuricemia
Rheumatoid Arthritis
Osteoarthritis
Spondylitis
NAFLD
Unit-V Endocrinology &Dermatology
Adernal Gland Disorders
Diabetic Mellitus
Thyroid Disorders
Osteoporosis
Acne Vulgaris
Psoriasis
Scabies
Eczema
Drug Induced Skin Disorders
Vetiligo
Text Books
1. JG Hardman, LE Limbard (2001). Goodman & Gilman's- The
Pharmacological Basis of Therapeutics: McGraw-Hill publications.
2. Joseph DiPiro, Robert L, Talbert, Gary Yee, Gary Matzke, Barbara
Well, Michael Posey L (2011). Pharmacotherapy: A Pathophysiologic
approach. 8th ed: McGraw-Hill publications.
3. Roger Walker Clive Edwards (2003). Clinical pharmacy and
therapeutics. 3rd ed.: Churchill Living stone publications.
4. Dennis Kasper L, Eugene Braunwald, Stephen Hauser, Dan Longo,
Larry Jameson J, Anthony Fauci S (2005). Principles of Internal
Medicine. 16th ed.: McGraw Hill Publications.
5. Dr Mary Lee (1992). Basic Skills in Interpreting Laboratory Data. 4th
ed.: American Society of Health System Pharmacists.
6. Eric Herfindal T, Joseph Hirschman L (1984). Clinical Pharmacy and
Therapeutics. 3rd ed.: Williams & Wilkins publications.

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2012-2013

7. GK Mc Evoy (2004). American Hospital Formulary Services: American

Society of Hospital Pharmacists.
8. Graeme S Avery (1980). Drug treatment- principles and practice of
clinical pharmacology and therapeutics. 2nd ed.: Adis Press
publications.
9. Mary Anne Koda-Kimble (2008). Applied Therapeutics. 9th ed.:
Wolters Kluwer Health/Lippincott Williams & Wilkins publications.
10.Ramzi Cotran S, Vinay Kumar, Tucker Collins, Stanley Leonard
Robbins (1999). Robbins pathologic basis of disease. 6th ed. : Saunders
publications.
11.Relevant review articles from recent medical and pharmaHCPtical
Journals.
12.Russell Greene J, Norman Harris D (2008). Pathology and Therapeutics
for pharmacists - a basis for clinical pharmacy practice. 3rd ed.:
Pharmaceutical Press Chapman and Hall Publications.
13.Sir Stanley Davidson, Christopher Haslett (2002). Davidsons
Principles and Practice of Medicine. 16th ed.: Churchill Living stone
publications.
14.Society of Hospital Pharmacists of Australia (1997). Practice Standards
and Definitions: The Society publications.

2012-2013

21

I Year I Sem. M.Pharmacy (HCP)

(A41013) ADVANCED CLINICAL PHARMACY
Unit-I Introduction to clinical pharmacy
Definition, Scope, History and Development of clinical
pharmacy

Unit-II Professional Activities of a Clinical Pharmacist

Ward Round Participation
Medication History Interview
Drug Therapy Monitoring (Medication Chart Review, Clinical
Review, Therapeutic Drug Monitoring & Pharmacist
Interventions)
Adverse Drug Reaction Management
Drug Information & Poison Information
Patient Counseling
PharmaHCPtical Care
Drug Utilization evaluation (DUE) & Review (DUR)
Quality Assurance of Clinical Pharmacy Services
Unit-III
A) Patient Data Analysis
The patients case history, its structure & use in evaluation of
drug therapy, presentation of cases.
Communication skills, including patient counseling
techniques, medication history interview, teaching skills.
Understanding
common
medical
abbreviations
&
terminologies used in clinical practices.
B) Clinical Laboratory Tests used in the evaluation of diseases states
& interpretation of test results.
Haemotological, Liver function, Renal function, Thyroid
function tests.
Medical imaging techniques
Tests associated with cardiac disorders

22

2012-2013

Fluid & Electrolyte balance

Common tests in urine, sputum, faeces, CSF.
Sensitivity screening for common pathogenic microorganisms,
its significance, resistance in disease states & selection of
appropriate anti-microbial regimens.
Pulmonary function tests.
Unit-IV
A) Drug & Poison Information
Introduction to Drug information, resources available,
Systematic approach in answering drug information serve
queries
Critical evaluation of drug information and literature
Preparation of written and verbal reports
Establishing a drug information center
Poisons information-organisation and information resources
Poisons management in drug dependence and drug abuses
(opiates, cocaine, amphetamines, alcohols, benzodiazepines,
barbiturates, tobacco). Role of emetics, anti- emetics and
respiratory stimulants.
B) Evidence Based Medicine
Formulating Clinical Questions
Searching for the best evidence
Critical Appraisal of the evidence
Applying evidence to patients
Evaluation
Unit-V A) Medication Error and Medication Adherence
Categories and causes of medication error
Performance indicators of the medication use process
Categories of medication non-adherence
Role of pharmacists at medication error and medication
adherence
B) Pharmacovigilance
Scope, Definition and Aims of Pahrmacovigilance

2012-2013

23

Adverse Drug Reactions Classification, Mechanism,

Predisposing Factors, Causality Assessment [different scaled
used].
Reporting, evaluation, monitoring, preventing & management
of ADRs
Role of pharmacist in management of ADRs
Text Books
1. Hansen K N Parthasarath G (2004). A text book of clinical pharmacy
practice Essential concepts and skills. Orient longman Publications.
2. Joseph Price Remington (1990). Remington Pharmaceutical sciences.
16th ed. Mack Pub. Co. Publications..
3. Leon Shargel Alan H Mutnick Paul F Souney Larry N Swanson
(2004).Comprehensive pharmacy review. 5th ed. Lippincott Williams &
Wilkins publications.
4. Leon Shargel Andrew Yu Susanna Wu-Pong (2012). Applied
Biopharmaceutics & Pharmacokinetics. 6th ed.
McGraw Hill
Professional publications.
5. Malcolm Rowland Thomas Tozer N (1995). Clinical Pharmacokineticsconcepts and applications. 3rd ed. Williams and Wilkins Publication.
6. Relevant review articles from recent medical and pharmaceutical
literature.
7. Scott L Traub (1996). Basic skills in interpreting laboratory data. 2nd
ed. American Society of Health System Pharmacists Inc publications.
8. Sharon Straus E (2005). Evidence Based Medicine. 3rd ed. Churchill
Livingtone publications.
9. Society of Hospital Pharmacists of Australia (1997). Practice Standards
and definitions the Society of Hospital Pharmacists of Australia. The
society publications.

24

2012-2013

I Year I Sem. M.Pharmacy (HCP)

(A41014) COMMUNITY PATIENT CARE/COMMUNITY PHARMACY

Unit-I
Introduction to the concept of community pharmacy its activities
and professional responsibilities
a) The role of community pharmacy and its relationships to other local
health care providers
b) Prescribed medication order- Interpretation and legal requirements
c) Over the counter (OTC) sales
d) OTC medication list and counseling, Rational use of common OTC
medications
(Vitamins and tonics, iron preparations, analgesics, NSAIDs, cough
mixtures, anti-diarrial preparations)
Unit-II
Health Education and Community Pharmacy: Family planning, first aid,
communicable disease prevention, smoking cessation, screening
programs.

Unit-III
a) Services to nursing homes/clinics.
b) Community Pharmacy Management: Financial, material and staff
management, infrastructure requirements, drug information resources,
computers in community pharmacy.
c) Code of ethics for community pharmacy
d) Poly pharmacy and its implications
Unit-IV
A)Communication skills Principles and elements of communication
skills,

non

-verbal

communication

in

pharmacy,

barriers

in

communication, listening skills, questioning skills, explaining Skills.

Patient counseling in community pharmacy

2012-2013

25

B) Education and training staff, training and continuing education for

pharmacists, pharmacy students, Medical staff and students, nursing
skills , explaining skills and ethics in communication

Unit-V
A) Public Health Policy and Health Care System National &
International
B) Concept of Rational Use of Drugs Importance of rational drug
use, pharmacists role, drug use indication, guidelines for rational
prescribing.
C) Code of ethics for community pharmacists
Text Books
1. William E Hassan (1986). Hospital Pharmacy. 5th ed. Lea & Febiger
publications.
2. Allwood M C Fell J T (1980). Textbook of hospital pharmacy. John
Wiley & Sons publications.
3. Graeme S Avery (1980). Drug treatment- principles and practice of
clinical pharmacology and therapeutics. 2nd ed. india: Adis Press
publications.
4. Joseph Price Remington (1990). Remington Pharmaceutical sciences.
16th ed. india: Mack Pub. Co. Publications.
5. Relevant review articles from recent medical and pharmaHCPtical
literature
6. Sharon Straus E (2005). Evidence Based Medicine. 3rd ed. Churchill
Livingtone publications.

26

2012-2013

I Year I Sem. M.Pharmacy (HCP)

(A41210) PATHOPHYSIOLOGY AND APPLIED
PHARMACOTHERAPEUTICS-I LAB
The students are required to be posted to various clinical wards for their
exposure with therapeutic management and other clinical aspects. They are
expected to have experience and do a tutorial as well as case presentation in
the following clinical conditions. The students have to make at leas 10 case
presentations covering most common diseases found in the hospital to which
the college is attached. The student should also submit a record of the cases
presented. The list of clinical cases presented should include follow-up of the
clinical cases mentioned below from the day of admission till discharge and
presented in the SOAP (Subjective, Objective, Assessment and Plan) format.
The cases may be selected from the following departments
1. Cardiology
2. Respiratory System
3. Haematological Diseases & Nephrology
4. Gastroenterology & Rheumatology
5. Endocrinology & Dermatology
Assignments
The students are required to submit a minimum of three written
assignments (1500 to 2000 words) selected from the topics on different
disease conditions given to them. The students are required to discuss both the
clinical and therapeutic aspects in the same.

2012-2013

27

I Year I Sem. M.Pharmacy (HCP)

(A41211) ADVANCED CLINICAL PHARMACY LAB
Patient medication history interview, answering drug information
questions, patient medication counselling, participation in ward rounds.
Case studies related to laboratory investigations covering the topics dealt in
theory class.
1. Answering drug information questions (4)
(Queries related to Dosage, administration, contraindications,
adverse drug reactions, drug use in pregnancy and lactation, drug
profile, efficacy and safety)
2. Patient medication counselling (3) Common diseases like
Diabetes, Hypertension, Asthma, COPD, Acute Renal Failure,
chronic Renal Failure.
3. Case studies related to laboratory investigations (4) LFT,
Hematology, Thyroid, Renal, Cardiac Enzymes.
4. Patient medication history interview (2)
5. Medication order review (2)
6. Detection and assessment of adverse drug reaction and their
documentation (3)

Assignments
Drug information,
Patient medication history interview
Patient medication counseling
Problem solving in clinical Pharmacokinetics
Literature evaluation pertaining to therapeutic range used in
therapeutic monitoring of any two drugs frequently subjected for
TDM.
Critical appraisal of two recently published articles in the biomedical
literature, which deals with a drug or therapeutic issue.

28

2012-2013

I Year II Sem. M.Pharmacy (HCP)

(A42001) INTELLECTUAL PROPERTY RIGHTS AND DRUG
REGULATORY AFFAIRS
Intellectual Property Management:

Unit I : Types of IP, definition, scope, objectives Patents, types, contents of

patent, claims and types of claims, key terminology used in patents
(Application, examiner, prior art, priority, specifications, provisional
and non-provisional applications, claims, applicant, assignee, inventor,
anticipation, obviousness, infringement and invalidation).
Unit II : Filing process, provisional and non-provisional applications, PCT
filing process, Advantages, Patentability requirement: (Novelty,
Utility, non-obviousness, enablement and best mode), Understanding
on infringement, invalidation and litigations
Unit III : Indian patent act and post 1995 amendments US and European
patent act
Trademarks, copyrights, designs International
conventions, GATT, TRIPS, Paris convention, Patent cooperation
treaty.

Regulatory Affairs:
Unit IV: National drug regulatory requirements, national drug policy, Drugs
and Cosmetics Act and its amendments, over view of schedules,
details of schedule M, Schedule Y. US FDA, orange book, FDA
guidelines on IND, new drug approvals (NDA), ANDA approvals,
SUPAC changes and understanding on 505 (b) (2) applications.
Unit V : Office of generic drugs, recommendations on dissolution and bioequivalence requirements, types of ANDA filing (P I, II, III and
IV) PIV ANDA filing and process involved till the approval
Exclusivities (NCE, NS, NP, NDF, PED, ODE, PC exclusivity)
European regulatory agency, types of filing process (Centralized,
de-centralized, RMS countries), SPCs, SPC exclusivities, data
exclusivities, WHO, WIPO, ICH objectives and guidelines.

2012-2013

29

Text Books:
1. Guarino (2002). New drug approval process. 3rd ed. New York: Marcel
Dekker Publication.
2. Commercial Manual on Drugs and Cosmetics (2004) 2nd edition.
3. Vijay Malik (2006). Drugs and Cosmetics act. 11th ed. Lucknow:
Publications Eastern Book.
4. S.H. Wiling (2003). Good Manufacturing Practices for Pharmaceuticals.
2nd ed. New York.: Marcel Decker.
5. P.Das and Gokul Das., Protection of Industrial Property rights.
6. S.N. Katju (2009). Hand book of Law of Drugs. 5th ed. Allahabad: Law
Publications.
7. Original Laws Published by Govt. of India
8. Hussain Laws of drugs in India,
9. R.A.Guarino, (2009). New Drug Approval Process. 4th ed. New York.:
Marcel Decker.
10.fda.org,wipo.int,patentlawlinks.com, hc-sc.gc.ca,ich.org

30

2012-2013

I Year II Sem. M.Pharmacy (HCP)

(A42002) PHARMACOLOGICAL SCREENING METHODS AND
CLINICAL RESEARCH
Unit I
Care Handling and breeding techniques of laboratory animals, Regulations for
laboratory animals, CPCSEA guidelines, alternatives to animal studies, Good
laboratory Practices.
Unit II
Bioassays: Basic principles of Biological standardization: Methods used in the
bio-assay of Rabbis Vaccine , Oxytocin , Tetanus Antitoxin and Diphtheria
Vaccine . Test for pyrogens.
Unit III
Toxicity tests: OECD guidelines, determination of LD50, acute, subacute and
chronic toxicity studies.
Unit IV
Organization of screening for the Pharmacological activity of new substances
with emphasis on the evaluation cardiac, psychopharmacological, antiinflammatory, analgesic and anti diabetic.
Unit V
Clinical evaluation of new drugs, Phases of clinical trial, protocol design,
Ethics in human research.
Pharmacovigilance: Definition, collection of data, reporting, assessment of
Post marketing surveillance, periodic safety update reports, Risk-benefit
assessment
Text Books:
1. Robert A Turner and Peter Hebborn (1979). Screening methods in
Pharmacology: . 2nd ed. New York: Academic publishers.
2. HG Vogel and WH Vogel (2010). Drug discovery and evaluation . Berlin
Heideleberg: Springerverlag.
3. SK Kulkarni (2012). Handbook of experimental pharmacology . 4th ed. Delhi:
Vallabh Prakashan.
4. David Machin, Simon Day and Sylvan green (2007). Textbook of clinical trials .
2nd ed. USA: Jhon Wiley & Sons Ltd.
5. Giovanna di ignazio, Di Giovanna and Haynes (2001). Principles of clinical
research . Hampshire: Wrightson Biomedical publishing Ltd.
6. ICH of technical requirements for registration of pharmaceuticals for human use,
ICH harmonized Tripartite guidelines - Guidelines for good clinical practice, E6
(May 1996).
7. Central drug standard control organization (2001). Good clinical practice Guidelines for Clinical trials on pharmaceutical products in India. New Delhi:
Minister of Health.
8. David Machin, Simon Day, Sylvan Green (2007). Textbook of clinical trials .
USA: John Wiley & Sons publications
9. Giovanna di Ignazio, Gareth Hayes (2001). Principles of clinical research.
London: Routledge publications.
10. Vogel HG., Vogel WH (2006). Drug discovery and evaluation-Pharmacological
Assays. 3rd ed. Berlin, Germany: Springer verlag publications

2012-2013

31

I Year II Sem. M.Pharmacy (HCP)

Advanced Pharmacology II
(A42012) Clinical Pharmacokinetics and Therapeutic Drug Monitoring
1. Introduction to Clinical pharmacokinetics.
a. Primary pharmacokinetic parameters
b. Interrelationship between primary pharmacokinetic parameters
and their effect on plasma concentration-time profile
c. Therapeutics Dosage regimens for special populations
d. Physiologic variables Affecting drug clearance
2. Design of dosage regimens:
Nomograms and Tabulations in designing dosage regimen, Conversion
from intravenous to oral dosing, Determination of dose and dosing
intervals, Drug dosing in the elderly and pediatrics and obese patients.
3. Pharmacokinetics of Drug Interaction:
a. Pharmacokinetic drug interactions
b. Inhibition and Induction of Drug metabolism
c. Inhibition of Biliary Excretion.
4. Therapeutic Drug monitoring:
a. Introduction
b. Individualization of drug dosage regimen (Variability Genetic,
Age and Weight , disease, Interacting drugs).
c. Indications for TDM. Protocol for TDM.
d. Pharmacokinetic/Pharmacodynamic Correlation in drug therapy.
e. TDM of drugs used in the following disease conditions:
cardiovascular disease, Seizure disorders, Psychiatric conditions,
and Organ transplantations.
5. Dosage adjustment in Renal and hepatic Disease.
a. Renal impairment
b. Pharmacokinetic considerations in renal impairment
c. General approach for dosage adjustment in Renal disease.
d. Measurement of Glomerular Filtration rate and creatinine
clearance.
e. Dosage adjustment for uremic patients.
f. Extracorporeal removal of drugs.
g. Genetic polymorphism in Drug metabolism: Cytochrome P-450
Isoenzymes.
h. Effect of Hepatic disease on pharmacokinetics.

32

2012-2013

Text Books
1. Alfonso Gennaro R (2000). Remington: The Science and Practice of
Pharmacy. 16th ed.: Lippincott Williams & Willkins publications.
2. Brahmankar

DM,

Jaiswal

SB

(1998).

Bio-pharmaceutics

and

Pharamcokinetics. 2nd ed.: Vallabh Prakashan publications.

3. Gilbaldi

Milo

(1991).

Bio-Pharmaceutics

and

Clinical

Pharmacokinetics. 4th ed.: Lea and Febiger publications.

4. Robert

Notari

(1987).

Bio-Pharmaceutics

and

Clinical

Pharmacokinetics. 4th ed. : Marcel Dekker Inc publications.

5. John

Wagner

(1971).

Bio-Pharmaceutics

and

relevant

Pharmacokinetics: Drug Intelligence Publications.

6. Leon Shargel, Andrew Yu, Susanna Wu-Pong (1993). Applied
Biopharmaceutics

&

Pharmacokinetics.

6th

ed.:

McGraw-Hill

publications.
7. Relevant review articles from recent medical and pharmaceutical
literature
8. Rowland M, Tozer TN (1995). Clinical Pharmacokinetics concepts
and applications. 3rd ed.: Lea & Febiger publications.
9. Scott L Traub (1996). Basic skills in interpreting laboratory data. 2nd
ed.: American Society of Health System Pharmacists Inc publications.
10.Shargel

L,

Yu

AB

(1993).

Applied

Bio-Pharmaceutics

and

Pharmacokinetics. 2nd ed.: Appleton & Lange publications .

11.Rowland,

Tozer(1996).

The

Society

publishers

Pharmacokinetics . 2nd ed.: Williams and Wilkins Publication.

Clinical

2012-2013

33

I Year II Sem. M.Pharmacy (HCP)

(A42013) PATHOPHYSIOLOGY AND APPLIED
PHARMACOTHERAPEUTICS II
Pathophysiology and applied Pharmacotherapeutics of diseases associated
with following system/diseases with of special reference to the drug of choice.
Unit-I
Neurology & Psychiatry
Epilepsy,
Parkinsons Disease
Multiple sclerosis
Headache: Migrane & Tension Type
Pain Management
Stroke
Alzheimers Disease
Anxiety Disorders
Bipolar Disorders
Depressive Disorder
Schizophrenia, Psychosis
Sleep Disorders
Substance Related Disorders
Unit-II
Oncology (Blood cancer and Solid tumors)
Basic Principles in Cancer Therapy, General Introduction To
Cancer Chemotherapy Agents
Atiangiogenic agents
Chemotherapy of Brest Cancer
Chemotherapy of Lung Cancer
Chemotherapy of Head / Neck Cancer
Leukemia
Management of Chemotherapy Nausea/ Vomiting
Pallative Care
Colorectal Cancer
Lyphomas
Prostate Cancer

34

2012-2013

Unit-III
Infectious Diseases
Antimocrobial Regimen Selection
Central Nervous System Infections Meningitis
Endocarditis
Fungal Infections, Invasive
Gastrointestinal Infections
HIV/AIDS
Influenza
Intraabdominal Infections
Respiratory Tract Infections Upper & Lower
Gastroeneritis
Sepsis & Septic Shock
STDs
Surgical Prophylasis
Tuberculosis
Urinary Tract Infections & Prostatitis
Unit-IV
Gynecologic & Obstetric Disorders / Ophthalmology/ Eye Disorders
Menopause/ Hormone Replacement Therapy In Women
Pregnancy & Lactation : Therapeutic Considerations
Contraception.
Conjunctivitis
Glaucoma
Eye infections
Unit-V
Nutritional Disorder & Immunology
Assessment & Nutritional Requirement
Enteral Nutritrion
Obesity
Total Parenteral Nutrition
Immune Disease Pathogenesis, Mechanism of action of drugs
Orphan
diseases(Sjogren's
Syndrome,
Paget
Disease
Extramammary, progeria)

2012-2013

35

Glucocorticoids Anti inflammatory, Anti allergic &

Immunosuppressive actions in tissue as well as organ
transplantation
Vaccines, Toxiods and other immunobiologics

Text Books
1. JG Hardman, LE Limbard, (2001). Goodman & Gilman's- The
Pharmacological Basis of Therapeutics: 10th edition; McGraw-Hill
publications.
2. Joseph DiPiro, Robert, L., Talbert, Gary Yee, Gary Matzke, Barbara
Wells, Michael Posey, L., (2011). Pharmacotherapy: A
Pathophysiologic approach: 8th edition; McGraw-Hill publications
3. Roger Walker, Clive Edwards, (2003). Clinical pharmacy and
therapeutics: 3rd edition; Churchill Living stone publications
4. Dennis Kasper, L., Eugene Braunwald, Stephen Hauser, Dan Longo,
Larry Jameson, J., Anthony Fauci,S.,(2005). Principles of Internal
Medicine: 16th edition; McGraw Hill Publications.
5. Eric Herfindal, T., Joseph Hirschman, L., (1984). Clinical Pharmacy
and Therapeutics: 3rd edition; Williams & Wilkins publications
6. GK Mc Evoy (2004). American Hospital Formulary Services: Published
by American Society of Hospital Pharmacists.
7. Graeme S. Avery (1980). Drug treatment- principles and practice of
clinical pharmacology and therapeutics: 2nd edition; Adis Press
publications.
8. Mary Anne Koda-Kimble (2008). Applied Therapeutics: 9th edition;
Wolters Kluwer Health/Lippincott Williams & Wilkins publications.
9. Ramzi Cotran, S., Vinay Kumar, Tucker Collins, Stanley Leonard
Robbins, (1999). Robbins pathologic basis of disease: 6 th edition;
Saunders publications.
10.Russell Greene, J., (2008). Norman Harris, D., Pathology and
Therapeutics for pharmacists - a basis for clinical pharmacy practice: 3rd
edition; Pharmaceutical Press Chapman and Hall Publications.
11.Sir Stanley Davidson, Christopher Haslett (2002). Davidsons
Principles and Practice of Medicine: 19th edition; Churchill Living stone
Publications

36

2012-2013

I Year II Sem. M.Pharmacy (HCP)

(A42014) HOSPITAL PHARMACY
nit-I Introduction:
The role of hospital pharmacy department and its relationship to other
hospital departments and staff.
Unit-II Hospital Drug Policy:
a) Pharmacy and therapeutic committee (PTC)
b) Hospital Formulary
c) e-Medicine
Unit-III . a)Hospital Committee
- Infection committee
- Research and ethical committee
b) Developing therapeutic guidelines
c) Hospital pharmacy communication - Newsletter.
Unit-IV Pharmacoepidemiology:
i.

ii.

iii.

iv.

Definition & Scope Origin and evaluation of

pharmacoepidemiology need for pharmacoepidemiology, aims
and applications.
Measurement of outcomes in pharmacoepidemiology outcome
measure and drug use measures, prevalence, incidence and
incidence rate, Monetary units, number of prescriptions, unit of
drugs dispensed, defined daily doses and prescribed daily doses,
medications adherence measurements.
Concept of risk in pharmacoepidemiology
Measurement of risk,
Attributable risk and relative risk
Time- risk relationship and odds ratio
Pharmacoepidemiological Methods Includes theoretical aspects
of various methods and practical study of various methods with
the help of case studies for individual methods.
Drug Utilization Review
Case Reports
Case Series

2012-2013

37

Surveys of drug use

Cross-sectional studies
Cohort studies
Case Control studies
Case- Cohort studies
Meta-analysis studies,
Spontaneous Reporting
Prescription Event Monitoring &
Record Linkage system
v.

Sources of data for pharmacoepidemiology studies

Ad Hoc data sources and automated data systems

vi.

Selected special applications of pharmacoepidemiology

Studies of vaccine safety
Hospital pharmacoepidemiology
Pharmacoepidemiology and risk management
Drug induced birth defects

Unit-V Pharmacoeconomics
Definition, history, needs of pharmacoeconomic evaluations Role in
formulary management decisions
Pharmacoeconomic evaluation - Outcome assessment and types of
evaluation Includes theoretical aspects of various methods and practical
study of various methods with the help of case studies for individual
methods: Case- minimization, Cost- benefit, Cost-effectiveness, CostUtility, Health Insurance - Medical Insurance.
Applications of Pharmacoeconomics Software and case studies
Text Books
1. Allwood M C Fell J T (1980). Textbook of hospital pharmacy. 3rd ed.:
John Wiley & Sons publications.
2. Brain

Strom

Stephen

Kimmel

(2011).Pharmacoepidemiology. 4th ed.

E
Wiley

Sean

Hennessy
Interscience

publications.
3. William E Hassan (1986). Hospital Pharmacy. 5th ed. Lec and Febiger
Publications.

38

2012-2013

4. Randy Vogenber F (2000). Introduction to Applied Pharmacoeconomics

McGraw-Hill Publications.
5. Graeme S Avery (1980). Drug treatment- principles and practice of
clinical pharmacology and therapeutics. 2nd ed.

Adis Press

publications.
6. Joseph Price Remington (1990). Remington Pharmaceutical sciences.
16th ed. Mack Pub. Co. Publications.
7. Sharon

Straus

(2005). Evidence

Based

Elsevier/Churchill Livingstone Publication.

Medicine.

3rd

ed.

2012-2013

39

I Year II Sem. M.Pharmacy (HCP)

(A42210) PATHOPHYSIOLOGY AND APPLIED
PHARMACOTHERAPEUTICS-II LAB

The students are required to be posted to various clinical wards for their
exposure with therapeutic management and other clinical aspects. They are
expected to have experience and do a tutorial as well as case presentation in
the following clinical conditions. The students have to make at least 10 case
presentations covering most common diseases found in the hospital to which
the college is attached. The student should also submit a record of the cases
presented. The list of clinical cases presented should include follow-up of the
clinical cases mentioned below from the day of admission till discharge and
presented in the SOAP (Subjective, Objective, Assessment and Plan) format.
The cases may be selected from the following diseases:
1. Neurology& Psychiatry
2. Oncology
3. Infectious Diseases
4. Gynecologic & Obstetric Disorders/ Ophthalmology
5. Nutritional Disorder & Immunology
Assignments
The students are required to submit a minimum of three written assignments
(1500 to 2000 words) selected from the topics on different disease conditions
given to them. The students are required to discuss both the clinical and
therapeutic aspects in the same.

40

2012-2013

I Year II Sem. M.Pharmacy (HCP)

(A42211) Hospital Pharmacy Lab
The student is expected to perform ABC and VED analysis on the given
data on drugs used in the hospital, participate in activity session involving
issues regarding pharmacy and therapeutic committee, prepare a model
monograph for a drug formulary, critically analyse the given data on hospital
pharmacy budget, work flow patterns etc., perform patient medication
interview and counselling and present drug profiles one new drugs.
ASSIGNMENTS
The student is expected to perform the following and report.
Comparison of prescription handling in two community pharmacies.
Audit of OTC sales over a 24 hour period in a local community
pharmacy ].
Role of community pharmacists in health education, family planning,
first aid, smoking cessation screening programmes, immunisation, etc.
Code of ethics for community pharmacies.
Summary of the advice and recommendations which should be provided
to the customers at a community pharmacy.
Select a new drug, which has recently been marketed in India for the
first time.
Prepare a report for a hospitals Drug and Therapeutic Committee, and make a
case either for or against the addition of this new drug on to the hospitals
formulary. Issues, which you may need to cover, include the drugs
pharmacology, its clinical use, the opinions of relevant hospital consultants
and a cost comparison with existing therapies for the same condition for which
the new drug is indicated.
Examine and report on the drug distribution methods used in a local
hospital .
Examine and report on the purchase and inventory of drugs in a local
hospital.