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Institute & Department of Psychiatry (LIM-23), University of Sao Paulo Medical School, Rua Dr. Ovdio Pires de Campos 785, 05403-010 So Paulo, SP, Brazil
Department of Pharmacology, Institute of Biomedical Sciences, University of Sao Paulo, Avenida Professor Lineu Prestes 1524, 05508-900 So Paulo, SP, Brazil
art ic l e i nf o
a b s t r a c t
Article history:
Received 18 January 2015
Received in revised form
23 January 2015
Accepted 29 January 2015
Available online 7 February 2015
Background: Few studies have investigated gender difference and associated disability among workers.
Comprehensive investigations concerning the occurrence and consequences of depression in workplace
are scarce. The study aims to evaluate how workers perceive depression in workplace, as well as to
examine depression-related disabilities by gender.
Methods: This is a cross-sectional web-based survey of 1000 Brazilian workers recruited from Internet
sources. Participants answered an online questionnaire about depressive symptoms and related consequences in the workplace.
Results: Common symptoms attributable to depression were crying, loss of interest, and sadness. Almost one
in ve (18.9%) participants reported had ever been labeled by a health professional as suffering from
depression. However, the majority of ever-depressed workers (73.5%) remained working. Performancerelated impairments were reported by around 60% of depressed workers who continued working. Over half
of them also complained about cognitive symptoms (concentration difculties, indecisiveness, forgetfulness),
with men reporting more cognitive dysfunctions than women. One in three workers had taken off work due
to depression (mean 65.7 out-of-role days), with these periods being lengthier for men than women.
Limitations: Some depressive events might have occurred before working age, since the participants have
self-reported the diagnosis of health professionals in past timeframe. The representativeness of recruited
workers was reliant upon the availability of Internet service.
Conclusions: The ndings suggest that identication and management of symptoms of depression should be
set as a priority in worker's health care. General and gender-related strategies to handle depression in the
workplace are recommended.
& 2015 Elsevier B.V. All rights reserved.
Keywords:
Depression
Gender difference
Cognitive symptoms
Disability
Workplace
1. Introduction
Depression is one of the leading causes of burden of disease
worldwide (Murray and Lopez, 1996), but there are insufcient
studies examining the effects of depression in the workplace. Individuals with depression report more decline in productivity than
those without depression (Herrman et al., 2002; Kessler, 2012). As
such, comprehensive data of depression-related work performance
and loss productivity are major gap of health knowledge, where information on expenditure, impairment, morbidity, and accident
injury is jointly combined (Oortwijn et al., 2011).
Occupational health professionals are most concerned with
clinical depression, a term used to describe any type of depression
that produces signicant personal distress and/or problems in functioning (Myette, 2008). This common disorder can manifest across
http://dx.doi.org/10.1016/j.jad.2015.01.058
0165-0327/& 2015 Elsevier B.V. All rights reserved.
49
2. Methods
2.1. Design and setting
The investigation was a cross-sectional survey on perceived depression in the workplace. This study was conducted in accordance
with guidelines of the International Chamber of Commerce (ICC) and
European Society for Opinion and Marketing Research (ESOMAR,
2013), where all workers self-reported their attitudes and perceived
symptoms of depression through Internet (Evans-Lacko and Knapp,
2014). This survey is the Brazilian branch of a multicentric survey
launched by European Depression Association (EDA) (2014).
2.2. Sampling and recruitment
Recruited from Internet sites, eligible participants were panelists of
Internet portals, service providers, online stores, airlines, communities,
etc., with audited customer databases. The sample size of 1000 participants was determined in accordance with the standard of national
representativeness for marketing and opinion research (ESOMAR,
2013). Data were weighted to adjust the representativeness of the
target prole: Brazilian residents, aged 1664 year-old, current workers, or have worked and managed within the last 12 months. We have
targeted a general population sample taking into consideration the age
stratum criterion, as currently or have been previously employed
individuals could not be selected. This approach had engaged a broad
range of socio-demographic proles by natural fallout. For targeting
the sample, there was a random extraction on needed demographics
and quotas structure on age, gender and region.
The participants were allowed to ll out only one form after
receiving an invitation email for the panel. Personal data were checked and duplicates were removed. No quotas on company size were
applied. This procedure was multisourced, closed, and by invitation
only and has followed ESOMAR's quality controls to guarantee unique participants and to avoid fraud.
2.3. Instrument
This investigation used a 13-item questionnaire elaborated by
European Depression Association (2014), which was translated
and adapted for use in BrazilianPortuguese speaking respondents
50
Regarding current working status, 79% of participants were fulltime workers, 17% part-time, and 4% was previously employed in
the past 12 months. Concerning the work position, 900 were employees and 100 managers from 100 different sized companies. Most
of companies (52%) were of large size (with more than 250 employees), 28% medium (51250 employees) and 20% small (150
employees). Almost one in ve participants (Fig. 1) reported ever
being labeled by a doctor/health professional as having depression
(n189), with a men/women ratio of 1:1.8.
Table 1
Demographic characteristics of the participants (n 1000).
Variable
Gender (%)
Male
Female
Mean age (yo., SD)
Age bracket (%)
1824 year
2534 year
3544 year
4554 year
5564 year
Marital status (%)
Married
Cohabiting
Single
Separated or divorced
Widowed
Educational level (%)
Up to 8 years
811 years
12 or more years
Region of Brazil (%)
North
Northeast
Southeast
South
Middle-West
Income per month (%)
Low a
Medium b
High c
Weighted proportion
589
411
57.3%
42.7%
36.8 year (11.6)
162
307
259
196
76
17.4%
30.1%
25.3%
19.2%
8.0%
423
176
329
62
6
41.2%
17.8%
33.2%
6.7%
1.1%
764
226
10
76.4%
22.6%
1.0%
75
224
129
414
158
8.0%
23.8%
7.1%
44.6%
16.4%
44
632
262
4.5%
65.2%
24.3%
yo.: year-old; SD: standard deviation; Missed data were omitted in the tabulation.
a
b
c
Total sample
(n = 1000; 900 workers,
100 managers)
3. Results
3.1. Demographics
Ever labeled
depressed in
working age
63 taken off work (33.3%)
126 kept working (66.7%)
2; p
63.0
21.7
68.9
9.0
59.6
25.1
65.4
11.7
67.9
16.8
72.3
5.1
Forgetfulness
Difculty planning activities
Changes in weight and
appetite
Trouble sleeping/insomniannn
Loss of interest nnnn
Other symptoms
Cognitive symptoms
8.7
24.8
38.3
10.2
26.7
32.9
6.6
22.1
46.0
49.9
68.4
0.2
33.7
48.9
64.5
0.3
39.0
51.3
74.0
0.0
26.0
7.138; 0.008
9.908; 0.002
5.311; 0.021
12.896;
o 0.0001
3.988; 0.046
NS
17.441;
o 0.0001
NS
10.001; 0.002
NS
18.353;
o 0.0001
Depressive symptoms
Total %
51
Table 3
Perceived behaviors and disabilities indicating depression in the workplace by total
sample and gender.
Depressive symptoms
Total %
Men % Women
%
n 1000 n 589 n411
2; p
16.9
42.4
18.8
43.1
14.1
41.4
3.862; 0.049
NS
15.3
24.3
30.7
16.6
27.0
31.7
13.4
20.4
29.2
NS
5.658; 0.017
NS
73.1
70.5
69.9
65.0
77.6
78.3
Forgetfulness
Falling asleep at work
Increased/prolonged sick leave
Other behaviors
20.2
10.4
33.6
0.7
19.2
9.8
30.6
0.3
21.7
11.2
38.0
1.2
7.236; 0.007
20.652;
o 0.0001
NS
NS
5.935; 0.015
NS
NS: non-signicant.
NS: non-signicant.
n
Among those never depressed individuals (N 811) there was a signicant
difference (2 5.452; p 0.02) between men and women (59.8% vs. 68.0%).
nn
Among those ever-depressed individuals (N 189) there was a signicant
difference (2 5.628; p 0.018) between men and women (54.8% vs. 71.4%).
nnn
Among those ever-depressed individuals (N 189) there was a signicant
difference (2 4.087; p 0.043) between men and women (45.2% vs. 60.0%).
nnnn
Among those never depressed individuals (N 811) there was a signicant
difference (2 8.211; p 0.004) between men and women (64.2% vs. 73.9%).
Cognitive symptoms encompass trouble concentrating, indecisiveness, and/or
forgetfulness.
During the last period of reported depression, the most experienced symptoms among those ever-depressed workers (n 189) were
low mood or sadness (71%) and loss of interest (71%), followed by
sleep problems (57%), crying (55%), and weight and appetite changes
(47%). Cognitive dysfunctions, considering the items of difculty of
concentration, or indecisiveness, or forgetfulness, accounted for 53%
of ever-depressed ones. Comparing gender differences, women reported signicantly more crying (70.5% vs. 34.5%; 2 24.33, po0.0001)
and loss of interest (81.9% vs. 56.0%; 2 10.08, po0.0001) than men
(data not shown).
Since the age they started working, one-third of the 189 workers
whom were ever labeled as depressed had taken time off work. One in
four (25.7%) participants reported that they had taken off work during
the last time they had been labeled depressive. Therefore, the vast
majority of depressed participants (66.774.3%) continued working in
contrast to those who have stopped working because of depressive
symptoms, irrespective of depressed period and/or gender (Fig. 1).
In last time, among those workers who remained working after
being labeled depressed by a health professional (n139), 68% reported withdrawing from colleagues, 40% taking more time to complete jobs and indecisiveness, and 37% making more mistakes and
52
4. Discussion
Observable depressive symptoms, such as sadness, lethargy, negativity and mood changes, are hallmarks of classical depression, affecting more women than men (Weissman and Klermann, 1992; Brown
and Harris, 2001; Kessler, 2003; Bromet et al., 2011). The results of this
survey indicate that there were more women being labeled depressed
than men during their occupational lifespan. The manifestations of
depressive symptoms differ between sex, in terms of perception, frequency, and psychopathology. Women report more symptoms more
overt and somatic complaints , but also are more liable to seek help.
In contrast, men endorse fewer symptoms but more covert and cognitive complaints , show less help-seeking behaviors, and tend to
require longer period to recover from a depressive episode. The
manifestations of psychomotor and cognitive functioning seem to
affect unequally both genders (Carragher et al., 2011; AlexandrinoSilva et al., 2013; Schuch et al., 2014). Possibly, as depression is more
prevalent among women and as they use more health services, current nosological descriptions such as ICD (World Health Organization,
1992) and DSM (American Psychiatric Association, 2013) might have
put more emphasis on symptomatic constellation of depression reported by women. Though gender-specic attitudes also have shaped
general opinion of depression in workplace, the difference of manifestation of depression in occupational context has received insufcient attention from most of epidemiological surveys.
Some researchers (e.g., Nolen-Hoeksema et al. (1999), Kessler
(2003) and Bromet et al. (2011)) describe women as more vulnerable to depressive symptoms than men because they are more
likely to experience chronic negative strain, to have a low sense of
mastery, and to engage in ruminative coping. Clinically depressed
women are not difcult to identify in work settings: dejected
mood and loss of interest in usual activities are noticeable, along
Fig. 2. Average number of days taken off work because of depressive symptoms, all
workers who taken off work (n 63) and by gender.
with numerous other symptoms that accompany depression. Population-based investigations underscored that depressed women used
to cry more and report more loss of interest than men (Carragher et al.,
2011; Alexandrino-Silva et al., 2013). While women are diagnosed
mainly by exploring their feelings (Nolen-Hoeksema et al., 1999), men
can be diagnosed by paying attention to their behaviors, for example,
psychomotor functioning and cognitive impairments (Martin et al.,
2013). The underlying mechanisms of depression might be liable to
similar hormone-mediated response to stress as tend-and-befriend
in women and ght-or-ight in men (Taylor et al., 2000).
Male depression is widespread, deeply misunderstood, and too
often misdiagnosed. Symptoms of depression are usually more
covert or masked among men (Hart, 2001). They do not connect
with others, but tend to withdraw from their peers, unwilling to
self-perceive themselves as depressive unless they experience a
distressing symptomatic pattern (Real, 1999; Hart, 2001). Some
men express depression through frustration and anger, along with
the classic symptoms of male depression like: irritability, short
temper, refusal to talk, overreaction to news, dissatisfaction with
meals or noise, withdrawal from friends or colleagues (Cochran
and Rabinowitz, 2000). Men can run away from their depressive
pain and hide some may be drowning sorrows in alcohol and
substance use until committing life-threatening suicide in extreme
cases (Kilmartin, 2005; Brownhill et al., 2005). This scenario
suggests the need for education to improve men's help-seeking
attitudes and to enhance workers' willingness to seek specialty
mental health services. Male workers should be encouraged to be
aware of the common depressive symptoms and the need to look
for early treatment/advice (Oliffe and Phillips, 2008).
Those depressed individuals who remained working can be
affected by distressing symptoms of depression, with great interference in work performance (Addis and Mahalik, 2003; Cornally and
McCarthy, 2011; Farrimond, 2012). In current study, three out of four
depressed workers attended work while sick, possibly resulting in
huge impact for the companies. In the case of presenteeism, cognitive
impairments of depression (such as indecisiveness, forgetfulness and
inattention) are associated with low productivity (Martin et al.,
2013). Over half of ever-depressed participants reported these covert
cognitive impairments as severe symptoms of depression, which
intensity is disabling enough to impact daily routine (Naismith et al.,
2007). Regardless taking off work or remaining at work, male
depressed workers in our study seemed to report more impact in
performance due to these symptoms than women. Particularly,
executive function, working memory, attention, and psychomotor processing were associated with diminished productivity
as whole (Lee et al., 2012; Trivedi et al., 2013). Therefore, addressing
cognitive dysfunction may have vital therapeutic implication in the
workplace (Baune et al., 2010; Godard et al., 2012), since performance variability seemed to be better explained by cognitive functioning than severity of depression symptoms (McIntyre et al., 2013,
2015; Papakostas, 2014; Trivedi and Greer, 2014).
It is no surprise that many men, although deeply depressed, go
untreated (Fujii et al., 2012). The chronic course of depression may
be associated with delay of care seek and lengthy time to recover
from depressive episodes (Berndt et al., 1998, Conradi et al., 2011).
Men are less likely to perceive depression and utilize mental
health services (Fujii et al., 2012; De Visser and McDonnell, 2013).
The mastery of job control and situational severity can inuence
on the timing of help seeking (Vashdi et al., 2012). Furthermore,
only about half of workers with depression received treatment and
fewer than half of treated workers received treatment consistent
with treatment guidelines in a recent US study (Kessler et al.,
2008b). While women display more favorable help-seeking attitudes concerning mental health needs (Kessler et al., 1981;
Mackenzie et al., 2006; Coen et al., 2013), depressed men used
to postpone medical care and take longer period to return to work
(mean absenteeism period of 80 days). Notwithstanding, many
sick leaves can be prevented if there are better policies in the
companies to deal with those milder depressed employees in early
stage of disability. This topic needs our attention, mainly in the
business world of workplace. The recent Well-Being Index survey
conducted by Gallup-Healthways among US employees has estimated the cost of incremental absenteeism due to depression as
USD 23 billion (Gallup, 2014). Analyses of occupational compensation data in Brazil showed that male workers were the group of
the highest health burden (Sousa Santana et al., 2012; Santana
et al., 2012). Since most of depressed workers remained in the job
and performance reduction cannot be easily estimated, the economic loss of presenteeism while depressed should be judiciously
addressed in the companies. Under-diagnoses and under-treatment of depressed men in workplace are a red ag for the managers to implement strategies for solving negative attitudes concerning their mental health needs, shortening the delay to seek
help. In addition, male workers should be encouraged to be aware
of the common depressive symptoms and the need to look for
timely treatment/advice. Early identication, proactive help by
managers and colleagues, proper referral, and adequate resource
provision are some corporate ingredients to avoid productivity fall
or sick leave of those depressed workers.
53
5. Conclusions
Findings of the current investigation in Brazilian workforce are
invaluable source to compare with other Latin America and developing countries at similar economical stage. Besides considering how
depressive symptoms may affect the companies' productivity, the
inclusion of variable sex in the dataset of occupational health is important to appreciate the growing participation of women in the context of market economy, allowing reducing its impact to the individual, the society, and the companies as whole. Paradoxically,
although women were viewed as a vulnerable group in workplace,
depressed male workers emerged as a group with more unmet needs
that require extensive attention.
In line with the literature, our study underscores the higher
likelihood of women suffering from depression than men, whereas
men take longer time than women to return to work in the case
of sick leave. The disability and the burden of depression should
be seriously handled in the organizations, as around one in ve
Brazilian workers has been labeled as suffering from depression in
their active professional period. However, the stigma of mental
disorders seems to haunt the workplace of many depressed
individuals. Both the workers and managers appear to neglect the
impact of common cognitive impairments when depressed worker
remained in their activities, regardless frequent reports of decient
work productivity, with deterioration of environment climate and
further negative consequences to company's efciency.
Depression must be considered an interactive relationship between
individuals with their personal and environmental needs in workplace
setting. The identication of this devastating and onerous condition in
organizations may be greatly improved by including those covert and
cognitive symptoms of depression affecting the workers. Therefore,
proper tools for coping with and treating depression should be offered
to the workers: well-being and awareness promotion, educational programs, suitable resource provision, explicit protective labor policies
can help those workers to seek care, diminishing the fear of being
dismissed in the time of economic crisis. Finally, so as to bringing back
those with depression to the workplace, the current study calls for a
greater integration between corporate stakeholders and academic investigations on mental health of the employees.
Role of funding source
H. Lundbeck A/S sponsored the survey. The Ipsos Mori Healthcare department
conducted the eldwork. Ogilvy Health PR London managed the survey, shared the
data to the authors and had no further inuence in the reported results, the
decision of publishing, and the nal content of manuscript.
Conicts of interest
All authors declare no conict of interest.
4.1. Limitations
Before extending the results to Brazilian workforce, some limitations should be pondered in the data interpretation. First, selfreported information obtained from netquest using non-standardized instruments for diagnosis of depression should be cautiously compared with surveys conducted with clinical interviews.
The depressive events might have occurred before their working
age in some individuals, as no assessment with standard instruments has been applied to the participants. Recall bias might have
occurred, as the recovered memories for personal episode of depression in past timeframe could be reported without precision and
completeness. Furthermore, uneven availability of Internet service
in non-developed countries can affect the representativeness of
the recruited sample. Some disadvantaged individuals and population strata that do not have access to or are unfamiliar to electronic resources might be underrepresented in the study.
Acknowledgments
The current investigation was carried out in conjunction with the European
Depression Association (http://www.europeandepressionday.com/idea.html).
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