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Staphage Lysate (SPL) is an all natural staphylococcal biologic effective in providing longterm control of a persistent staphylococcal skin infection in dogs, frequently called
recurrent canine pyoderma. SPL stimulates the natural immune system of the dog, thereby
reducing the recurrences of infection and eliminating the need for repetitive use of
antibiotics. Treating recurrent canine pyoderma with round after round of antibiotics can
be frustrating for the veterinarian, onerous and expensive for the dog owner and stressful
for the dog.
condition. It is unique in that it is a whole bacterial cell preparation from common virulent
Staph strains that have been solubilized through the use of polyvalent staphylococcal
bacteriophage.
We work collaboratively with veterinarians everywhere who treat staphylococcal skin
infection. Our experience can be a valuable resource. We also provide direct access to a
board certified veterinary dermatologist to answer any questions and guide you through
the treatment process. We recognize the complexity and challenges surrounding diagnosis
and treatment of this condition.
Our History
Staphage Lysate (SPL) was licensed for human use
in 1959 in the United States. The utility of
bacteriophage and the lysates in the treatment of
staphylococcal infections was reported by Robert
Lincoln, MD in 1948. He also recognized that the
staphylococcal phage lysates were particularly
useful in the treatment of immune compromised
patients and patients with chronic skin infections
such as furunculosis and folliculitis.
Dr. Lincoln helped found Lincoln Laboratories that is now known as Delmont Laboratories.
In 1986 Delmont Laboratories applied to the U. S. Department of Agriculture for a
veterinary license for the use of Staphage Lysate (SPL) in the treatment of recurrent
canine pyoderma. (USDA True Name: Staphylococcus aureus Phage Lysate). The USDA
license was issued in 1987. (Note: Staphage Lysate (SPL) is not currently sold for human
use).
Delmont Laboratories has subsequently obtained veterinary licenses in Canada (English
speaking 1992, French speaking 2000) and in Brazil (2001).