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Joylent is a ready to drink milkshake mix in powdered form to be mixed with water, with sweetener

and added vitamins and minerals.


Instructions for use: Mix 173g (3.5 scoops) of Joylent with 500ml water. Every bag contains 3 servings.
Ingredients: oatmeal (gluten), Joylent Vitamix [Maltodextrin, Trisodium citrate * 2H2O, Sodium chloride, LCholine bitartrate, Calcium carbonate (precipitated), Magnesium oxide (heavy),Vitamin C (ascorbic acid),
Vitamin E 50% (dl-alpha-tocopheryl acetate, 500 IU), Niacin (niacinamide), Vitamin A (retinol acetate)
325000 IU, Pantothenic acid (calcium-D- pantothenate), Vitamin D3, Copper sulphate, Vitamin K1
5%,Vitamin B1 (thiamine mononitrate), Vitamin B6 (pyridoxine hydrochloride), Vitamin B2 (riboflavin),
Potassium iodate, Chromium chloride, Folic acid, Biotin, Vitamin B12 (cyanocobalamin)], soy flour, whey
protein concentrate (cow's milk, lactose, soy lecithin, sucralose, flavor aroma, natural dye, thickener: guar
gum), ground flaxseed, flavour enhancer [flash-dried fruit powder (strawberry/banana [5%])/vanilla powder/
raw cacao].
Allergens: may contain traces of nuts (peanuts).

Sources:
Oatmeal - plant - Avena sativa
Whey Protein concentrate - cow milk- animal - cow
Soy flour - plant - Glycine max NON GMO

ground flaxseed - plant - Linum usitatissimum


flash- dried fruit powder (strawberry/banana [5%] - Fragaria ananassa/Musa
acuminata
Vanilla powder - plant - V. planifolia
Cacao powder - plant - Theobroma cacao

Vitamin Mix

Maltodextrin

maize or wheat/ maize

Sodium chloride
Calcium carbonate
(precipitated)

synthetic

flow chart

synthetic, mineral

flow chart

L-Choline bitartrate
Magnesium chloride *
6H2O

synthetic

flow chart

synthetic
plant (Maize, Sugar Beet),
mineral

origin, composition

synthetic
vegtable (corn) =>
fermentation

flow chart

Potassium citrate
Magnesium oxide (heavy)
Vitamin C (ascorbic acid)
Vitamin E 50% (dl-alphatocopheryl acetate, 500 IU)

flow chart

vegtable (maize), synthetic

Potassium iodate

synthetic

n.a.

Niacin (niacinamide)
Vitamin A (retinol acetate)
325000 IU

synthetic
vegetable( beet sugar,
maize, acacia), synthetic)
synthetic,
vegetable(maize, sugar
cane, coconut),
animal wool grease (fat)

flow chart

synthetic

flow chart

Folic acid

petrochemical

flow chart

Chromium chloride

synthetic

n.a.

Biotin
Vitamin B12
(cyanocobalamin)

synthetic

flow chart
flow chart

Vitamin K1 5%

fermentation
synthetic,
vegetable(maize, acacia)

Vitamin B2 (riboflavin)

vegetable (maize starch)

Copper sulphate
Vitamin B6 (pyridoxine
hydrochloride)

synthetic

Vitamin D3
Pantothenic acid (calciumD-pantothenate)

synthetic

flow chart

flow chart

flow chart

flow chart

Basic flow-chart: Sodium chloride Ph.Eur./UP


Plant: dsalz GmbH, Bad Fried richshal llGermany

ffi4ffi W

&dgffifu.w

Rock salt means sodium


chloride with the main natural
impurities clay and anhydrite

Rock salt feed

Dissolving
lnsolubles
(Clay, anhydrite,
magnesium hydroxide)

Dosage of sodium hydroxide


(pH regulation) and flocculant

Sedimentation

Evaporation I Crystallisation

Dosage of antifoam additive


(silicone product)

Slurry (Sodium chloride / Brine)

Debrin ing (centrifuges)

Drying (hot air)

Cooling (cold air)


Fines, graines
with oversize
Sodium chloride extra pure,
without anticaking agent

Packaging
25 I 50 ks PE baqs,

{--

Final inspection and test

Version: 19 May 201O/Dr. Gtzfriedleg

Vitamin D3 100 SD

Preparation of Matrix
(water soluble
components in water)

Preparation of
Oil Phase

Emulsification (Highpressure)

Pressure control

Holding

Spray Drying

Sifting

Packaging

Temperature control

Screen size

Nutraceuticals

Production route: Vitamin D3 100 SD


Herstellungsmethode (Calciumcarbonat, schwer, Magnesia 449):
Calcit

Zerkleinern

Trocknen

Siebung

Mahlen

Analysieren, CaCO3

Verpacken
Comments on the production process:
Only natural Calcium carbonate (CaCO3) from 5 m to 4 6 mm is micronized. Raw material in
stones of 10 cm arrives in the main plant from the quarry, 8 km far, and here it starts to be
micronized. Micronization takes place in two different lines: technical line and pure line. In the
technical line all products for technical market are obtained, while in the pure line only products for
both food and pharmaceutical market are manufactured. Both lines are completely closed and
separated and no contaminations are possible.
Thanks to the dry and friable raw material, during the process no liquids or chemicals are used and
only compressed air is used for cleaning machinery.
In the process there are three metal detectors. They are able to detect only ferrous materials,
whereas for the pure line a glass procedure is in place.
The plant works for 24 hours per day, 7 days per week. Maintenance is done during summer time
and winter holidays when machinery is off.
Controls of critical steps:
Raw material:
In-process-controls:
Finished product:

chemical analysis
periodically throughout the manufacturing process; physical analysis
and insoluble matter in acetic acid
chemical and physical analysis
71805

Seed culture in mother bottle culture

Primary seed culture

Second seed culture

Fermentation

Fermentation broth Primary acidification

Continuous lysis

Membrane filtration

Adsorption in column

Eluate vacuum concentration

Transformation Concentration eluate collection

Zhejiang Medicine Co., Ltd.


Flow Chart of Biotin Pure
Raw material/
Packaging material

Storage in
warehouse

Dibenzyl biotin/
Hydrobromic acid
Checking
materials

Water/
Methylbenzene

Debenzylation

Dropping liquid
caustic/Keeping PH

Storage in
Plant

Receiving by
Plant

Thermal
insulation

Recovering
hydrobromic acid

Extracting/
Demixing

Checking
equipments

Liquid caustic

HB/Methylbenzene
solution

Extraction

Adjust pH in
aqueous layer

Filtration

Crystallization/
Centrifugalization

Water/ Activated
carbon/EDTA

Biotin crude

Refluxing/
Filtration

Drying

Milling

CCP1

Packaging

Storage in
Plant

Sampling

CCP2

Test by QC

Release by
QA

Storage in
warehouse

Transport to
customer

1/1

Production Flow Chart


Tripotassium Citrate

citric acid, potassium


source, water

neutralization

crystallization

centrifugation

Detailed Flow Chart


A. A1 station:
COCl

drying

sieving

NO2

packaging

p-nitrobenzoyl chloride
Alkali liquor
Water
Monosodium glutamate

Condensation

Stand to delamination
Version 05.11, supersedes 04.07

-1/1-

TPC_G10_EN

The layer of Toluene

Hydrochloric acid (Ind. Grade)

Iron powder

Adjusting

Recollect

Reduction

Distillation

Ammonium chloride

Toluene
Temperature Preservation

Filter

Decolorization

Filter

Hydrochloric acid (Ind. Grade)

Salt formation

Human Nutrition

Flow Chart:
Dry Vitamin A-Acetate 325 GFP/E

Manufacturing site: BASF Health & Nutrition, Denmark

Emulsion of Vitamin A-Acetate

Powdering agent

Atomization

Air

Drying

Air

Mixing of dried batches


to standard

Dry Vitamin A-Acetate 325


GFP/E

February 2012

Choline Bitartrate Processing Flow

For information only not for regulatory purposes no update service - August 2005

Manufacturing site:

Balchem Italia srl


Via del Porto snc
28040 Marano Ticino (NO)
Italy

CONFIDENTIAL

JIANGXI TIANXIN PHARMACEUTICAL CO.,LTD

Process Chart of
Pyridoxine Hydrochloride
Starting materials: 4-methyl-5-ethoxyoxazole, n-propyl dioxepin
Flow chart:

Ethanol
4-Methyl-5-ethoxyoxazole
Addition reaction

Aromatization

n-Propyl dioxepin

Drying

Milling/Sieving

Purification

Hydrolysis

Finished product

Remark: CCP is the Milling process. Inside the milling machine there is a screen. The
integrity of the screen and the remains of material on the screen are inspected and recorded
for each batch production.
Human Nutrition

Flow Chart:
Calcium D-Pantothenate
Manufacturing site: Ludwigshafen, Germany

Add.: Leanjiang Industrial Zone, Leping, Jiangxi, China


Tel: +86-798-6702928
E-mail: qa2@txpharm.com

P.C.: 333300
Fax: +86-798-6702928
Website: http://www.txpharm.com

Calcium -alaninate

D-pantolactone

Page 1 of 2

Methanol

Crystallisation
Water

Spray drying

Calcium D-pantothenate

For information only not for regulatory purposes no update service - January 2005

Manufacturing Flow Chart

Version 1, 03.2011

Dry Vitamin K1 5% GFP


PRD no. 30041002
Manufacturing site: BASF A/S, Denmark

Emulsion of Vitamin K1

Powdering agent

Atomization

Air

Drying

Air

Sieving

Dry Vitamin K1 5% GFP

This document, or any answers or information provided herein by BASF, does not constitute a legally binding obligation of BASF.
While the descriptions, designs, data and information contained herein are presented in good faith and believed to be accurate, it is
provided for your information only and not to be used for purposes of pharmaceutical registrations.
There is no automatic update service for this information.

Flow chart of Niacinamide manufacture process

SELLER MAKES NO WARRANTY OF ANY KIND; EITHER EXPRESS OR IMPLIED, BY FACT OR LAW, INCLUDING
WARRANTIES OF MERCHANTABILITY OR FITNESS FOR PARTICULAR PURPOSE.

METHOD OF MANUFACTURE
Magnesium Oxide, heavy

Magnesium Oxide

Demin. Water

Suspension

Purification

Drying

Packing

The raw materials are ordered by the Dr. Paul Lohmann GmbH KG according
to internal specifications or pharmacopoeia, controlled by Quality Control and
released for production thereafter.
Only Demineralised Water is used as a cleansing agent and solvent.
The final product is analysed by QC according to methods of specification or
pharmacopoeia.
If all tests comply with the limits, the material is released for shipment.

Version 12.07.2012 Kn/VS

FS-C46-Et-2.doc
1/1