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Hazard
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Chemical characterization
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Population context
Dose-response
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Extrapolation of in vivo
animal results to humans
Exposure
assessment
Receptors
Pathways of exposure
Concentration, duration
Internal dose
Population data
Exposure data (biomonitoring
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monitoring)
Risk
characterization
Quantitative risk
assessment models
Emerging Technologies
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Hazard Identification
Toxicity Profiling
Cluster Analysis
Cell Population
Kinetics
Risk
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Mode of Action
Population
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EC Efficiency
2.34
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Mean Graph
Mean Graph For
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ARPE
A549
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48 hr
72 hr
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100
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Toxic Effect
In Vitro Dose
GHS Classification
In Vivo LD50
LD50 (mmol/kg) vs KC50 (mM)_geomean in 6 Human Cell Lines
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Exposure
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Health Risk
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Chemical
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DNA adducts
Organelle
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Cellular
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Systems
biology
Injury
Stress
Gene activation
Apoptosis
Protein production
Autophagy
Signaling
Necrosis
Transformation
Gene mutation
Ligand binding
Reporter gene
Enzyme activity
Gene expression
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Biomarkers
Chemical x-actions
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Speed (High-throughput screening)
Early indication of hazard
Human relevance
Multiple cell types (Cell panel)
Exposure relevance
Mixtures
Quick evaluation of environmental incidents
Cost-effective
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