Date

30-Mar

Lecture topic

Reading

Overview, biomolecules, DNA structure and information flow

IGA 1-26

1-Apr

Mendels first law (Law of Segregation)

IGA 27-34

3-Apr

The chromosomal basis of segregation, Aneuploidies

IGA 35-38, 40-49, 599-606

6-Apr

Sex linkage and Pedigree analysis

IGA 50-65

8-Apr

Mendels second law: Independent assortment

IGA 81-96

10-Apr

Recombination, Linkage and gene mapping

IGA 121-132

13-Apr

More on recombination and mapping

IGA 132-145 (not 4.4)

15-Apr

Gene interactions and pathways, Complementation

IGA 219-226

17-Apr

Analyzing gene Interactions, Epistasis

IGA 211-218, 226-233

20-Apr

Prokaryotic and eukaryotic model organisms

IGA 759-773

22-Apr

Review for exam I

24-Apr

DNA replication

IGA 251-279

27-Apr

From DNA to RNA: transcription

IGA 283-306, 359-361

29-Apr

RNA processing and export

IGA 283-306, 359-361

1-May

The genetic code

IGA 309-319

4-May

Protein translation

IGA 319-330

6-May

Bacterial gene regulation: lac operon

IGA 381-397

8-May

Eukaryotic gene structure and expression

IGA 292-298, 415-424

11-May

Monitoring and controlling gene expression

IGA 426-434

13-May

Review for exam II

15-May

Genetic engineering: Recombinant DNA

7:30-9:30 pm Wednesdays

Assignments due

Concept inventory (participation credit)

review session #1 (attendance is optional)

assignment #1 due 4pm

review session #2 (attendance is optional)

assignment #2 due 4pm

7:00-9:30 PM: First Midterm Exam

review session #3 (attendance is optional)

assignment #3 due 4pm

review session #4 (attendance is optional)

assignment #4 due 4pm

7:00-9:30 PM: Second Midterm Exam

IGA 341-354

18-May

Genetic engineering: Transgenic organisms

IGA 369-377

20-May

Genes in action: Developmental genetics

IGA 449-460

22-May

Genes in action: Cancer genetics

IGA 580-583

25-May

Memorial Day, no class

27-May

Genes in action: neurogenetics

29-May

Genes and Genomes: Genome structure and genetic variation, natural selection, homIGA 487-520, 787-735, 752-755

1-Jun

TBA

review session #5 (attendance is optional)

assignment #5 due 4pm

review session #6 (attendance is optional)

assignment #6 due 4pm

Review for exam III

June 8th

7-9PM: Third Midterm Exam

Text: IGA is Introduction to Genetic Analysis , Tenth edition; by A. Griffiths, S. Wessler, S. Carroll, & J. Doebley 2012; W H Freeman & Co, New York; ISBN 13: 978-1-4292-2943-8, ISBN
10: 1-4292-2943-8 (black cover w/ petunia). Note that an electronic version of the book is available through the Freeman website as an alternative to the print version.
Clicker: ResponseCard NXT; Students must register their NXT clickers in Canvas. Only you may deliver responses from your clicker for in-class questions and the concept inventory.
Logistics
Class sessions: 12-12:50 pm MWF LRII
Always bring clickers to class (ResponseCard NXT)
Office hours: Monday AND Friday 4-6 pm
Graduate TAs hold weekly drop-in office hours, and together with TAs from 215-2, hold weekly review sessions from 7:30-9 in Ryan Auditorium on the Wedensday nights that we don't have a
Problems TAs are undergraduates who took BIOL215 previously and can give assistance in problem solving in drop-in office hours:
Additional problems are not graded but provide an added relevant opportunity to develop your skills at solving genetics problems. The intent is not to learn formulas for solving a litany of part
The best way to demonstrate an understanding of a subject is to be able to use that knowledge in a real or simulated situation. Be forewarned that there is no machine-like way of solving
these problems. The three main resources at your disposal are the genetic principles just learned, logic, and trial and error.
Relevant for Exam 1
Chpt. 2: 34, 36, 40, 42, 43, 44, 45, 51, 52, 55, 56, 72, 74
Chpt. 3: 12, 13, 14, 18, 20, 24, 27, 31, 36, 47, 52, 57
Chpt. 4: 12, 13, 14, 20, 21, 22, 34, 42, 49, 57, 58
Chpt. 6: 12, 13, 14, 15, 16, 17, 27, 32, 33, 35, 60, 77

Relevant for Exam 2

Chpt. 7: 19, 21, 23, 25, 26, 27, 28, 29, 30, 31, 32
Chpt. 8: 8, 12, 14, 16, 18, 19, 20, 25, 27
Chpt. 9: 12, 13, 14, 16, 17, 19, 20, 25, 27, 38, 39, 40, 42, 43, 44
Chpt. 11: 9,10,17,18,19,20,21
Chpt 12: 12, 13,14,15,26,27,28,29,34
Relevant for Exam 3
Chpt. 10: 2, 6, 14, 16, 20, 24, 23, 27
Chpt 13: 14, 21, 22
Chpt. 20: 17, 22
TBA
The solved problems at the end of each relevant chapter are also excellent accounts of the problem solving process for particular topics.