Documentos de Académico
Documentos de Profesional
Documentos de Cultura
Radiation
Protection
July 2007
American Association of
Physicists in Medicine
Summer School
0.279 (mrem/hr)/mCi
Lateral
#HVL's
0.103 (Sv/hr)/MBq
0.383 (mrem/hr)/mCi
not as
anisotropic as it
might seem
0.018 (Sv/hr)/MBq
compare this to
0.014 (Sv/hr)/MBq or
0.05 (mrem/hr)/mCi
for 99mTc: 18F values
factor of 8 larger!
jon.anderson@utsouthwestern.edu
X-ray 1
(average primary for
rad room)
PET2
1
2
4
5.3 (1/4)
9.9 (7/16)
19.0 (3/4)
8
10
32.5 (1 5/16)
46.0 (1 13/16)
Even a
single halfvalue layer
for PET is
an
expensive
proposition!
jon.anderson@utsouthwestern.edu
Arrival of patient
Receive doses
Injection of Pt
Even a
X-ray
Not true(average
in PET.
Asfor
we will see, it is truesingle
that halfprimary
room)1-3 HVL's of shielding. We
normally weradneed
value layer
1
0.044
1/16) we need,
5.3 (1/4)
tend
to put
just(<what
due to $$$.
for PET is
2
0.103 (< 1/16)
9.9 (7/16)
an
Implication:
every protection
we need
4
0.278 At
(< 1/16)
19.0 (3/4)point, expensive
to
all sources
can(1be5/16)
contributing
to
8 include0.718
(< 1/16) that32.5
proposition!
the
that(<point
multiple
injection
10 dose at
1.366
1/16) (i.e.46.0
(1 13/16)
rooms, scan rooms, etc.). Corresponds to
NCRP 147: Structural Shielding Design for Medical X-Ray Imaging Facilities
Simpkin,
2004, developed
for AAPM
Taskdownward.
Group on PET Facility Shielding
adjusting
protection
limit
PET2
jon.anderson@utsouthwestern.edu
that 1/16" is
(usually)
theRequired
answer, with some to
#HVL's
Lead
Thickness
spare. We usually
the "closest" point.
mm (in,calculate
to next 1/16)
1. NCRP 147: Structural Shielding Design for Medical X-Ray Imaging Facilities
2. Simpkin, 2004, developed for AAPM Task Group on PET Facility Shielding
3
A Revealing
Comparison of Lead
Remember this morning's bottom line: for DX,
we can apply 3 models
from NCRP
and find
Requirements:
X-Ray
vs 147
PET
1
jon.anderson@utsouthwestern.edu
Anterior
0.104 (Sv/hr)/MBq
0.383 (mrem/hr)/mCi
1.
2.
30-60 min
Assay of dose
Uptake of pharmaceutical
8-20 mCi
Position Pt
Release Pt
Scan
10-30 min
QA Check of Scan
* steps with
highest
technologist
exposure
Read study
Distribute to PACS or Media
AAPM Summer School, 2007
jon.anderson@utsouthwestern.edu
Magnitude of Technologist
Consistent with conventional nuclear
Exposure
medicine practice, most of technologist
dose comes from positioning, transport,
and injection.
Dose/Activity Handled
Sv/MBq
(mrem/mCi)
Technologist Doses
Over a two year period with the same technologists, we saw a
40% decrease in radiation dose per unit activity handled.
average dose/procedure
< 10 Sv (1 mrem)
0.150
0.100
2) For
Yearly:
9 Months:
0.050
0.000
Chisea
McElroy
UTSW
Roberts
Guillet
Biran
Yester Average
SI Units
Benetar Chisea
0.018
0.012
0.023
0.019
0.019
0.011
0.009
0.029
0.021
0.018
Conventional Units
0.067
0.044
0.085
0.069
0.069
0.041
0.032
0.107
0.077
0.066
Reference
7
jon.anderson@utsouthwestern.edu
Radioactive
Materials
Dock
Scan
Utility
Future Camera
Office 1
Room
Reading
Room
East Corridor
Hot
Toilet
Hot Lab
Injection Scan
Room 1
#2
Injection
#1
Scan
Room 2
Control
South Corridor
jon.anderson@utsouthwestern.edu
Laundry
West Corridor
Break
Room
Office 3
Office 2
Patients
Business
Office
Reception &
Waiting
jon.anderson@utsouthwestern.edu
Radioactive
Materials
Dock
Laundry
Reading
Room
South Corridor
West Corridor
Break
Room
jon.anderson@utsouthwestern.edu
Notes:
1) Floor
protection
(containers
weigh > 66 lbs)
2) Space needed
depends on how
often deliveries
are made; may
have >100 mCi
here at a time,
even for one
scanner
3) Extra
shielding may
be required
Office 2
Patients
Business
Office
Reception &
Waiting
jon.anderson@utsouthwestern.edu
11
10
Future Camera
Office 1
Room
East Corridor
If you can get involved
in the
Hot Lab planning, you can save
Office 3
architectural
Scan
Injection Scan
Room 2
Roomusing
1
#2
some
money,
by
distance
instead
Hot
Control
Injection
Toilet
of lead.
#1
Storage
jon.anderson@utsouthwestern.edu
12
Notes:
1) Calibrator
convenient to
dose storage
2) L Block
close to
calibrator
3) Note use of
special PET
carrier for
syringe
4) Note L
Block: thick
window, 2"
lead, 2" lead
wrap-around
AAPM Summer School, 2007
jon.anderson@utsouthwestern.edu
13
Notes:
1) All this lead requires solid support -- have a heart-toheart talk with the cabinet maker
2) Counter mount of calibrator decreases tech exposure
3) Extra shielding required on well counter to shield
from sources in scanner, calibration sources, patient in
scanner, etc.
4) Use tungsten syringe shields for dose reduction to
fingers.
AAPM Summer School, 2007
GE Discovery Series
2) To minimize
anomalous uptake
-minimize external
stimuli (false uptake!)
-keep patient quiet and
still on gurney or in
injection chair
14
Notes:
1) Injection room
Hot lab
PET/CT bay
are most likely areas to
need shielding
jon.anderson@utsouthwestern.edu
You need to
know which one
you're getting! -it may affect scan
time, injected
activity
15
Philips GEMINI
jon.anderson@utsouthwestern.edu
16
B=
jon.anderson@utsouthwestern.edu
17
P * d2
* T * Nw * (A0 * Ftot * t * Rt)
jon.anderson@utsouthwestern.edu
18
# patients/week
isotopes to be used, activity/pt
types of PET studies to be performed (brains, WB, cardiac)
uptake time and scan time for this equipment/study/center
dose delivery schedule (once a day?, multiples?); maximum
activity on hand
jon.anderson@utsouthwestern.edu
1 mSv/yr
(100 mrem/yr)
.02 mSv
(2 mrem)
5 mSv/yr
(500 mrem/yr)
Targets
controlled areas:
100 Sv/wk or
10 mrem/wk
jon.anderson@utsouthwestern.edu
Rate Constants
SI Units
15.5 (R/hr) m2/MBq
m2/MBq
m2/mCi
0.5291 (mrem/hr)
Phase
Uptake
Scanning
7:00 8:00 9:00 10:00 11:00 12:00 13:00 14:00 15:00 16:00 17:00
Time of Day
jon.anderson@utsouthwestern.edu
22
0.143 (Sv/hr)
Exposure Rate
Constant
Conventional Units
Effective Dose
Equivalent (ANS-1991)
11
uncontrolled areas:
20 Sv/wk or
2 mrem/wk
13
Dose Rate
[( Sv/hr)/MBq]
[(mrem/hr)/mCi]
Members of public
20
15
Patient Number
50 mSv/yr
(5000 mrem/yr)
Pregnant worker's fetus
5 mSv/9 mo
(500 mrem/9 mo)
jon.anderson@utsouthwestern.edu
Limitations
ALARA
per 10CFR20 Action Limit
Radiation workers
require CT x-ray
workload factors,
techniques,
include non-PET
CT work
workload
parameters:
pts/wk, mCi/pt
uptake,scan times
isotope type and
delivery scheds
18
F Injected Patient at 1 m
sources of variation:
delay time to measurement,
micturation status, exposure-todose conversion, etc.
TG-108 recommends
(0.092 Sv/hr)/MBq
(0.34 mrem/hr)/mCi
0.400
0.300
0.200
(mrem/hr)
0.6771recommends
TG-108
0.143
(Sv/hr)/MBq
(Sv/hr) m /MBq 0.6956 (mrem/hr) m /mCi
0.53 (mrem/hr)/mCi
for F-18 bare source
0.183 (Sv/hr)
0.188
m2/MBq
2
jon.anderson@utsouthwestern.edu
0.100
0.000
m2/mCi
2
23
Kearfott 1992
Chisea 1997
Cronin 1999
Benetar 2000
White 2000
Yester * 2005
(attenuation)
Massoth 2003
(unpubl.)
Average
SI Units
0.075
0.055
0.100
0.150
0.137
0.08866
0.097
0.100
Conventional Units
0.279
0.203
0.370
0.553
0.508
0.328
0.359
0.372
Source
about 20% of dose will be in bladder after 1-2 hours;TG108 uses 15%
AAPM Summer School, 2007
jon.anderson@utsouthwestern.edu
24
half
A e ln( 2) dT
0
160
Uncorrected
140
120
A 0 dT
0.8
Dose [microSv]
Reduction Factor Rt
Effect of Corrections
Cumulative Dose 1 m from Patient, 370 MBq F-18
180
0.6
0.4
100
60
40
0.2
80
A factor of 2
= 1/4" of lead
Inject @ 5 minutes
Void @ 65 minutes
20
0
0
20
40
60
80
100
120
140
160
180
200
20
40
60
80
Time [minutes]
jon.anderson@utsouthwestern.edu
25
B=
Uptake
Room:
Scan
Bay:
jon.anderson@utsouthwestern.edu
27
B +
x( B) :=
ln
1+
0.0100
0.0001
10
15
20
25
30
Thickness(mm)
35
40
200
jon.anderson@utsouthwestern.edu
B=
45
50
jon.anderson@utsouthwestern.edu
26
jon.anderson@utsouthwestern.edu
29
28
Archer Parameters
[cm-1]
[cm-1]
1.543
-0.4408
0.1539
-0.1161
0.5704
-0.3063
2.136
2.0752
0.6326
1
0.0010
180
P * d2
* T * Nw * (A0 * Ftot * t * Rt)
Douglas
Simpkin (2004)
Lead
160
12.8 includes the value of and the effects of voiding 15% of the
injected activity before imaging;
FU=exp(-0.693tU/T1/2), the physical decay of the isotope before the
patient enters scan bay
1.0000
140
B=
120
d2
10.9 is 1/ in (hr/Sv)(MBq/m2);
Ftot = 1 (no physical decay prior to injection, no
elimination)
Transmission
P*
* T * Nw * (A0 * Ftot * t * Rt)
B=
100
Time [minutes]
e
B ( x) 1 +
x ( B)
B +
1+
ln
jon.anderson@utsouthwestern.edu
30
P := 20 10
Dis tance:
d := 4 m
:= .092 10
Oc cupancy:
T := 1
Sv
Sv m
6
Nw := 40
6
Injected Ac tivity:
A 0 := 555 10 Bq
Decay/Elimination:
F := 1
Sourc e D uration:
t := 1hr
R( t ) = 0.831
Br :=
hr 10 Bq
P d
Br = 0.188
( )
xPb Br = 1.184cm
( )
xconc Br = 15.165cm
jon.anderson@utsouthwestern.edu
jon.anderson@utsouthwestern.edu
Oc cupancy:
T := 1
Nw := 40
Injected Ac tivity:
A 0 := 555 10 Bq
Decay/Elimination:
Sourc e D uration:
t := 0.5hr
T Nw A 0 F R( t ) t
Br = 0.334
( )
xPb Br = 0.807cm
( )
xconc Br = 11.278cm
jon.anderson@utsouthwestern.edu
32
jon.anderson@utsouthwestern.edu
CT Calculation
CT Angle
320 degrees
CT mAs/hr 40000 mAs
Exposure Tolerance:
34
0
0
0
0
2.54
3.105
2.54
0
0.159
0.159
0.636
0.636
0.636
0.159
0.318
0.636
0
0
0
0
0
0
0
0
0
0
0
90
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
1.571
B7
B8
barrier
definitions
B5
B6
jon.anderson@utsouthwestern.edu
Office/Lab
Corridor
Reading C Scan
Comment
Inj
T H
1
1
4
4
4
1
2
4
L-Block
PET-Net shipping case + local shield
1" lead storage case
no barriers counted
n control
s control
s hot lab
s inj 2
s inj 1
n inj area
s scan 2
e hot lab
Corridor
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
8
B4
Br :=
P d
R( t ) = 0.91
Lobby
Elevator
Ty
10.06
8.23
11.52
15.55
17.36
15.55
18.29
18.29
18.29
18.29
18.29
18.29
18.29
18.29
18.29
18.29
18.29
( 1hr)
ln( 2)
T half
( 1 15%)
F := e
Elevator
test point
results
shielding
material
definitions
Tx
-10.83
-9.60
-17.84
-12.80
-10.99
-9.60
-20.12
-18.29
-16.46
-14.63
-12.80
-10.97
-9.14
-7.32
-5.49
-3.66
-1.83
Sv m
hr 10 Bq
Reading
Total Target
Tot/Targ
Ratio
Loc_ID Occupancy Status Area
mR/wkmR/wk
1
1 OK control
12.66
100 0.12664
2
1 OK control
9.05
100 0.09049
3
0.25 OK hot lab
7.61
100 0.0761
4
1 OK reading room 3.62
100 0.03618
5
1 OK reading room 2.03
100 0.02026
6
1 OK reading room 2.44
100 0.02444
7
1 OK E wall
1.97
2 0.98403
8
1 OK E wall
1.81
2 0.90567
9
1 OK E wall
1.97
2 0.98286
10
1 OK E wall
1.97
2 0.98251
11
1 OK E wall
1.74
2 0.86885
12
1 OK E wall
1.70
2 0.85039
13
1 OK E wall
1.56
2 0.77788
14
1 OK E wall
1.41
2 0.70582
15
1 OK E wall
1.28
2 0.64054
16
1 OK E wall
1.14
2 0.57104
17
1 OK E wall
1.13
2 0.56277
Office/Lab
source
definitions
1
2
3
4
:= .092 10
Sv
Verification that no member of the public will be exposed to more than 100 mrem/yr
avg per hour
Input Data
Source XRate@1m
Sx
Sy
1 scan1
3.15 -14.4
10.49
511 Calculation
2 scan2
2.6 -4.43
8.6
Matl
Mu/Rho Rho
Mu
3 inj 1
3.8 -17.6
7.77
Concrete
0.0877
1.84 0.1614
4 inj 2
3.8 -17.6
8.81
Lead
0.161
11.34 1.8257
5 phan 1
1.1 -15.9
8.58
Lead tranmissions for CT Calc (NCRP49)
6 phan 2
1.1 -8.83
9.88
d[cm]
B
7 lab
54 -18.7
11
0
1
8 hot_ws
0.13 -17.8
11
0.159 2.63E-03
9 bath
0.45 -22.8
6.56
0.3180 5.47E-05
10 CT
-5.04
9.11
0.4760 1.09E-06
NPETSources
9
0.6350 1.00E-06
Source Area
3.15 scan1 control
2.60 scan2 control
3.80 inj 1
control
3.80 inj 2
control
33
Example Spreadsheet
XConst
d := 3 m
31
PathID
P := 20 10
Dis tance:
T Nw A 0 F R( t) t
DoseToTargetRatio
jon.anderson@utsouthwestern.edu
36
37
'HOT' LAB
2.480C
'HOT' TOILET
2.480G
CLINICAL
STORES
2.480H
SCAN
UTILITY
2.592
CORRIDOR
2.5
NURSE
2.481B
CORRIDOR
2.481
FUTURE
SCANNER BAY 1
2.591A
SCANNER BAY 2
2.591B
SCANNER BAY 3
2.591C
SUB-WAITING
2.481A
PHYSICIAN 1
2.450
CORRIDOR
2.482
CONTROL/OBSERVATION
2.591
PHYSICIAN 2
2.440
FILE ROOM
2.591G
MANAGER
2.591H
LAB
2.591F
READING 1
2.591E
READING 2
2.591D
Overall
design: No
lead in excess
of 3/8". North
wall of
injection
rooms, hot lab
shielded with
16" of drylaid, fulldensity
concrete block
jon.anderson@utsouthwestern.edu
Electrical
jon.anderson@utsouthwestern.edu
39
Electrical
Corridor
Elevator,
Lobby
Corridor
Glass Wash
Mechanical Space
Exterior
Floor Plan
38
Mechanical Space
INJECTION 1
2.480B
54"
54"
'HOT' TOILET
2.480A
Lobby
jon.anderson@utsouthwestern.edu
Elevator
DoseToTargetRatio
Elevator
Reading
Y image
Reading
Office/Lab
needed
Corridor
40
jon.anderson@utsouthwestern.edu
41
jon.anderson@utsouthwestern.edu
42
jon.anderson@utsouthwestern.edu
Acknowledgements
jon.anderson@utsouthwestern.edu
The
End
43
jon.anderson@utsouthwestern.edu
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