Question 2 (Weight 10%) Unit "Quiz: kidney" A glomerular syndrome dominated by grossly visible hematuria, mild to moderate proteinuria, and hypertension: ( )Chronic renal failure ( )Acute nephritic syndrome ( )Acute renal failure ( )Nephrotic syndrome
Question 3 (Weight 10%) Unit "Quiz: kidney" An autosomal recessive renal cystic disease that produces a complication of hepatic fibrosis: ( )Familial juvenile nephronophthisis ( )Acquired renal cystic disease ( )Adult-onset medullary cystic disease ( )Childhood polycystic kidney disease
Question 4 (Weight 10%) Unit "Quiz: kidney" Soluble mediator responsible for formation of crescents in glomerular injury: ( )chemokines ( )eicosanoids ( )fibrin ( )cytokines
Question 5 (Weight 10%) Unit "Quiz: kidney" A primary glomerulonephritis that produces splitting of the glomerular basement membrane on light microscopy: ( )Minimal change disease ( )Focal segmental glomerulosclerosis ( )Goodpasture syndrome ( ) Membranoproliferative glomerulonephritis
Question 6 (Weight 10%) Unit "Quiz: kidney" Most frequent cause of nephrotic syndrome in children: ( )Membranous glomerulopathy ( )Minimal change disease ( )Focal segmental glomerulosclerosis ( ) Membranoproliferative glomerulonephritis
Question 7 (Weight 10%) Unit "Quiz: kidney" In utero bilateral renal agenesis is most likely to produce: ( )Anencephaly ( )Gastroschisis ( )Oligohydramnios ( )Polycythemia
Question 8 (Weight 10%) Unit "Quiz: kidney" An 8-month-old male infant presents with progressive renal and hepatic failure. Despite intensive medical therapy, the infant dies. At the time of autopsy, the external surfaces of his kidneys are found to be smooth, but cut section reveals numerous cysts that are lined up in a row. What is the mode of inheritance of this renal abnormality? ( )Autosomal dominant ( )Autosomal recessive ( )X-linked dominant ( )X-linked recessive
Question 9 (Weight 10%) Unit "Quiz: kidney" A 28-year-old male with AIDS presents with moderate proteinuria and hypertension. Histologic sections of the kidney reveal the combination of normal-appearing glomeruli and occasional glomeruli that have deposits of hyaline material. No increased cellularity or necrosis is noted in the abnormal glomeruli. Additionally, there is cystic dilation of the renal tubules, some of which are filled with proteinaceous material. Electron microscopy reveals focal fusion of podocytes, and immunofluorescence examination finds granular IgM/C3 deposits. What is the best diagnosis for this renal abnormality? ( )Diffuse proliferative glomerulonephritis (DPGN) ( )Minimal change disease (MCD) ( )Focal segmental glomerulosclerosis (FSGS) ( )Membranous glomerulopathy (MGN)
Question 10 (Weight 10%) Unit "Quiz: kidney" Immune complexes located within the glomerular basement membrane would most likely be found in a patient with: ( )Acute glomerulonephritis (GN) ( )Membranous GN ( )Type II membranoproliferative glomerulonephritis ( )IgA nephropathy