1: Miller-Fleming L, Antas P, Pais TF, Smalley JL, Giorgini F,

Outeiro TF. Yeast

DJ-1 superfamily members are required for diauxic-shift
reprogramming and cell
survival in stationary phase. Proc Natl Acad Sci U S A. 2014 Apr 2.
[Epub ahead
of print] PubMed PMID: 24706893.

2: Rodrigues TM, Jerónimo-Santos A, Outeiro TF, Sebastião AM,

Diógenes MJ.
Challenges and promises in the development of neurotrophic factor-
based therapies
for Parkinson's disease. Drugs Aging. 2014 Apr;31(4):239-61. doi:
10.1007/s40266-014-0160-x. PubMed PMID: 24610720.

3: Vittori A, Orth M, Roos RA, Outeiro TF, Giorgini F, Hollox EJ;

REGISTRY
investigators of the European Huntington’s Disease Network. β-
Defensin Genomic
Copy Number Does Not Influence the Age of Onset in Huntington's
Disease. J
Huntingtons Dis. 2013 Mar 27;2(1):107-124. PubMed PMID: 24587836;
PubMed Central
PMCID: PMC3935171.

4: Vittori A, Breda C, Repici M, Orth M, Roos RA, Outeiro TF,

Giorgini F, Hollox
EJ; the REGISTRY investigators of the European Huntington's Disease
Network.
Copy-number variation of the neuronal glucose transporter gene
SLC2A3 and age of
onset in Huntington's disease. Hum Mol Genet. 2014 Feb 5. [Epub
ahead of print]
PubMed PMID: 24452335.

5: Wales P, Pinho R, Lázaro DF, Outeiro TF. Limelight on alpha-

synuclein:
pathological and mechanistic implications in neurodegeneration. J
Parkinsons Dis.
2013;3(4):415-59. doi: 10.3233/JPD-130216. PubMed PMID: 24270242.

6: McFarland KN, Huizenga MN, Darnell SB, Sangrey GR, Berezovska O,

Cha JH,
Outeiro TF, Sadri-Vakili G. MeCP2: a novel Huntingtin interactor.
Hum Mol Genet.
2014 Feb 15;23(4):1036-44. doi: 10.1093/hmg/ddt499. Epub 2013 Oct 8.
PubMed PMID:
24105466; PubMed Central PMCID: PMC3900110.
7: Sajjad MU, Green EW, Miller-Fleming L, Hands S, Herrera F,
Campesan S,
Khoshnan A, Outeiro TF, Giorgini F, Wyttenbach A. DJ-1 modulates
aggregation and
pathogenesis in models of Huntington's disease. Hum Mol Genet. 2014
Feb
1;23(3):755-66. doi: 10.1093/hmg/ddt466. Epub 2013 Sep 26. PubMed
PMID: 24070869.

8: Fagerqvist T, Näsström T, Ihse E, Lindström V, Sahlin C, Tucker

SM, Kasaryan
A, Karlsson M, Nikolajeff F, Schell H, Outeiro TF, Kahle PJ,
Lannfelt L,
Ingelsson M, Bergström J. Off-pathway α-synuclein oligomers seem to
alter
α-synuclein turnover in a cell model but lack seeding capability in
vivo.
Amyloid. 2013 Dec;20(4):233-44. doi: 10.3109/13506129.2013.835726.
Epub 2013 Sep
20. PubMed PMID: 24053224.

9: Pais TF, Szegő ÉM, Marques O, Miller-Fleming L, Antas P,

Guerreiro P, de
Oliveira RM, Kasapoglu B, Outeiro TF. The NAD-dependent deacetylase
sirtuin 2 is
a suppressor of microglial activation and brain inflammation. EMBO
J. 2013 Oct
2;32(19):2603-16. doi: 10.1038/emboj.2013.200. Epub 2013 Sep 6.
PubMed PMID:
24013120; PubMed Central PMCID: PMC3791374.

10: Basso E, Antas P, Marijanovic Z, Gonçalves S, Tenreiro S,

Outeiro TF. PLK2
modulates α-synuclein aggregation in yeast and mammalian cells. Mol
Neurobiol.
2013 Dec;48(3):854-62. doi: 10.1007/s12035-013-8473-z. Epub 2013 May
17. PubMed
PMID: 23677647.

11: Amaral M, Outeiro TF, Scrutton NS, Giorgini F. The causative

role and
therapeutic potential of the kynurenine pathway in neurodegenerative
disease. J
Mol Med (Berl). 2013 Jun;91(6):705-13. doi: 10.1007/
s00109-013-1046-9. Epub 2013
May 1. Review. PubMed PMID: 23636512.
12: Eisbach SE, Outeiro TF. Alpha-synuclein and intracellular
trafficking: impact
on the spreading of Parkinson's disease pathology. J Mol Med (Berl).
2013
Jun;91(6):693-703. doi: 10.1007/s00109-013-1038-9. Epub 2013 Apr 25.
Review.
PubMed PMID: 23616088.

13: Faria C, Jorge CD, Borges N, Tenreiro S, Outeiro TF, Santos H.

Inhibition of
formation of α-synuclein inclusions by mannosylglycerate in a yeast
model of
Parkinson's disease. Biochim Biophys Acta. 2013 Aug;1830(8):4065-72.
doi:
10.1016/j.bbagen.2013.04.015. Epub 2013 Apr 19. PubMed PMID:
23608058.

14: Tenreiro S, Munder MC, Alberti S, Outeiro TF. Harnessing the

power of yeast
to unravel the molecular basis of neurodegeneration. J Neurochem.
2013
Nov;127(4):438-52. doi: 10.1111/jnc.12271. Epub 2013 May 8. Review.
PubMed PMID:
23600759.

15: Amaral M, Levy C, Heyes DJ, Lafite P, Outeiro TF, Giorgini F,

Leys D,
Scrutton NS. Structural basis of kynurenine 3-monooxygenase
inhibition. Nature.
2013 Apr 18;496(7445):382-5. doi: 10.1038/nature12039. Epub 2013 Apr
10. PubMed
PMID: 23575632; PubMed Central PMCID: PMC3736096.

16: Taschenberger G, Toloe J, Tereshchenko J, Akerboom J, Wales P,

Benz R, Becker
S, Outeiro TF, Looger LL, Bähr M, Zweckstetter M, Kügler S. β-
synuclein
aggregates and induces neurodegeneration in dopaminergic neurons.
Ann Neurol.
2013 Jul;74(1):109-18. doi: 10.1002/ana.23905. Epub 2013 Aug 6.
PubMed PMID:
23536356.

17: Vicente Miranda H, Xiang W, de Oliveira RM, Simões T, Pimentel

J, Klucken J,
Penque D, Outeiro TF. Heat-mediated enrichment of α-synuclein from
cells and
tissue for assessing post-translational modifications. J Neurochem.
2013
Sep;126(5):673-84. doi: 10.1111/jnc.12251. Epub 2013 Apr 25. PubMed
PMID:
23534813.

18: Schildknecht S, Gerding HR, Karreman C, Drescher M, Lashuel HA,

Outeiro TF,
Di Monte DA, Leist M. Oxidative and nitrative alpha-synuclein
modifications and
proteostatic stress: implications for disease mechanisms and
interventions in
synucleinopathies. J Neurochem. 2013 May;125(4):491-511. doi:
10.1111/jnc.12226.
Epub 2013 Mar 19. Review. PubMed PMID: 23452040.

19: Donmez G, Outeiro TF. SIRT1 and SIRT2: emerging targets in

neurodegeneration.
EMBO Mol Med. 2013 Mar;5(3):344-52. doi: 10.1002/emmm.201302451.
Epub 2013 Feb
18. Review. PubMed PMID: 23417962; PubMed Central PMCID: PMC3598076.

20: Gonçalves S, Outeiro TF. Assessing the subcellular dynamics of

alpha-synuclein using photoactivation microscopy. Mol Neurobiol.
2013
Jun;47(3):1081-92. doi: 10.1007/s12035-013-8406-x. Epub 2013 Feb 8.
PubMed PMID:
23389286; PubMed Central PMCID: PMC3637893.

21: Amaral JD, Herrera F, Rodrigues PM, Dionísio PA, Outeiro TF,
Rodrigues CM.
Live-cell imaging of p53 interactions using a novel Venus-based
bimolecular
fluorescence complementation system. Biochem Pharmacol. 2013 Mar
15;85(6):745-52.
doi: 10.1016/j.bcp.2012.12.009. Epub 2012 Dec 19. PubMed PMID:
23261524.

22: Guerreiro PS, Huang Y, Gysbers A, Cheng D, Gai WP, Outeiro TF,
Halliday GM.
LRRK2 interactions with α-synuclein in Parkinson's disease brains
and in cell
models. J Mol Med (Berl). 2013 Apr;91(4):513-22. doi: 10.1007/
s00109-012-0984-y.
Epub 2012 Nov 27. PubMed PMID: 23183827; PubMed Central PMCID:
PMC3611031.

23: Repici M, Straatman KR, Balduccio N, Enguita FJ, Outeiro TF,

Giorgini F.
Parkinson's disease-associated mutations in DJ-1 modulate its
dimerization in
living cells. J Mol Med (Berl). 2013 May;91(5):599-611. doi:
10.1007/s00109-012-0976-y. Epub 2012 Nov 27. PubMed PMID: 23183826;
PubMed
Central PMCID: PMC3644405.

24: Marques S, Outeiro TF. Epigenetics in Parkinson's and

Alzheimer's diseases.
Subcell Biochem. 2013;61:507-25. doi: 10.1007/978-94-007-4525-4_22.
Review.
PubMed PMID: 23150265.

25: Lopes da Fonseca T, Correia A, Hasselaar W, van der Linde HC,

Willemsen R,
Outeiro TF. The zebrafish homologue of Parkinson's disease ATP13A2
is essential
for embryonic survival. Brain Res Bull. 2013 Jan;90:118-26. doi:
10.1016/j.brainresbull.2012.09.017. Epub 2012 Oct 31. PubMed PMID:
23123961.

26: Diógenes MJ, Dias RB, Rombo DM, Vicente Miranda H, Maiolino F,
Guerreiro P,
Näsström T, Franquelim HG, Oliveira LM, Castanho MA, Lannfelt L,
Bergström J,
Ingelsson M, Quintas A, Sebastião AM, Lopes LV, Outeiro TF.
Extracellular
alpha-synuclein oligomers modulate synaptic transmission and impair
LTP via
NMDA-receptor activation. J Neurosci. 2012 Aug 22;32(34):11750-62.
PubMed PMID:
22915117.

27: Sampaio-Marques B, Felgueiras C, Silva A, Rodrigues M, Tenreiro

S, Franssens
V, Reichert AS, Outeiro TF, Winderickx J, Ludovico P. SNCA (α-
synuclein)-induced
toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated
mitophagy.
Autophagy. 2012 Oct;8(10):1494-509. doi: 10.4161/auto.21275. Epub
2012 Aug 23.
PubMed PMID: 22914317.

28: Marques O, Outeiro TF. Alpha-synuclein: from secretion to

dysfunction and
death. Cell Death Dis. 2012 Jul 19;3:e350. doi: 10.1038/cddis.
2012.94. Review.
PubMed PMID: 22825468; PubMed Central PMCID: PMC3406593.
29: Marques SC, Lemos R, Ferreiro E, Martins M, de Mendonça A,
Santana I, Outeiro
TF, Pereira CM. Epigenetic regulation of BACE1 in Alzheimer's
disease patients
and in transgenic mice. Neuroscience. 2012 Sep 18;220:256-66. doi:
10.1016/j.neuroscience.2012.06.029. Epub 2012 Jun 21. PubMed PMID:
22728099.

30: Petroi D, Popova B, Taheri-Talesh N, Irniger S, Shahpasandzadeh

H,
Zweckstetter M, Outeiro TF, Braus GH. Aggregate clearance of α-
synuclein in
Saccharomyces cerevisiae depends more on autophagosome and vacuole
function than
on the proteasome. J Biol Chem. 2012 Aug 10;287(33):27567-79. doi:
10.1074/jbc.M112.361865. Epub 2012 Jun 21. PubMed PMID: 22722939;
PubMed Central
PMCID: PMC3431624.

31: Rosa P, Tenreiro S, Chu V, Outeiro TF, Conde JP. High-throughput

study of
alpha-synuclein expression in yeast using microfluidics for control
of local
cellular microenvironment. Biomicrofluidics. 2012 Mar;6(1):
14109-141099. doi:
10.1063/1.3683161. Epub 2012 Feb 9. PubMed PMID: 22662094; PubMed
Central PMCID:
PMC3365346.

32: Maxwell MM, Zaldivar-Jolissaint JF, Mai A, Outeiro TF, Kazanstev

AG.
Highlights of the Keystone Symposium: sirtuins in metabolism, aging
and disease.
EMBO Mol Med. 2012 Jul;4(7):557-60. doi: 10.1002/emmm.201201452.
Epub 2012 May
18. PubMed PMID: 22610822; PubMed Central PMCID: PMC3407943.

33: Szegő ÉM, Outeiro TF, Kermer P, Schulz JB. Impairment of the
septal
cholinergic neurons in MPTP-treated A30P α-synuclein mice. Neurobiol
Aging. 2013
Feb;34(2):589-601. doi: 10.1016/j.neurobiolaging.2012.04.012. Epub
2012 May 11.
PubMed PMID: 22579457.

34: de Oliveira RM, Sarkander J, Kazantsev AG, Outeiro TF. SIRT2 as

a Therapeutic
Target for Age-Related Disorders. Front Pharmacol. 2012 May 3;3:82.
doi:
10.3389/fphar.2012.00082. eCollection 2012. PubMed PMID: 22563317;
PubMed Central
PMCID: PMC3342661.

35: Kazantsev AG, Outeiro TF. Editorial on special topic: sirtuins

in metabolism,
aging, and disease. Front Pharmacol. 2012 Apr 24;3:71. doi:
10.3389/fphar.2012.00071. eCollection 2012. PubMed PMID: 22536186;
PubMed Central
PMCID: PMC3334976.

36: Sancenon V, Lee SA, Patrick C, Griffith J, Paulino A, Outeiro

TF, Reggiori F,
Masliah E, Muchowski PJ. Suppression of α-synuclein toxicity and
vesicle
trafficking defects by phosphorylation at S129 in yeast depends on
genetic
context. Hum Mol Genet. 2012 Jun 1;21(11):2432-49. doi: 10.1093/hmg/
dds058. Epub
2012 Feb 21. PubMed PMID: 22357655; PubMed Central PMCID:
PMC3349423.

37: Herrera F, Gonçalves S, Outeiro TF. Imaging protein

oligomerization in
neurodegeneration using bimolecular fluorescence complementation.
Methods
Enzymol. 2012;506:157-74. doi: 10.1016/B978-0-12-391856-7.00033-0.
PubMed PMID:
22341224.

38: Kemppainen S, Rantamäki T, Jerónimo-Santos A, Lavasseur G, Autio

H, Karpova
N, Kärkkäinen E, Stavén S, Vicente Miranda H, Outeiro TF, Diógenes
MJ, Laroche S,
Davis S, Sebastião AM, Castrén E, Tanila H. Impaired TrkB receptor
signaling
contributes to memory impairment in APP/PS1 mice. Neurobiol Aging.
2012
Jun;33(6):1122.e23-39. doi: 10.1016/j.neurobiolaging.2011.11.006.
Epub 2011 Dec
30. PubMed PMID: 22209410.

39: Gerhardt E, Gräber S, Szego EM, Moisoi N, Martins LM, Outeiro

TF, Kermer P.
Idebenone and resveratrol extend lifespan and improve motor function
of HtrA2
knockout mice. PLoS One. 2011;6(12):e28855. doi: 10.1371/
journal.pone.0028855.
Epub 2011 Dec 19. PubMed PMID: 22205977; PubMed Central PMCID:
PMC3242749.

40: Herrera F, Outeiro TF. α-Synuclein modifies huntingtin

aggregation in living
cells. FEBS Lett. 2012 Jan 2;586(1):7-12. doi: 10.1016/j.febslet.
2011.11.019.
Epub 2011 Nov 24. PubMed PMID: 22119730.

41: Ribeiro Morais G, Vicente Miranda H, Santos IC, Santos I,

Outeiro TF, Paulo
A. Synthesis and in vitro evaluation of fluorinated styryl
benzazoles as
amyloid-probes. Bioorg Med Chem. 2011 Dec 15;19(24):7698-710. doi:
10.1016/j.bmc.2011.09.065. Epub 2011 Oct 18. PubMed PMID: 22078413.

42: Näsström T, Gonçalves S, Sahlin C, Nordström E, Screpanti

Sundquist V,
Lannfelt L, Bergström J, Outeiro TF, Ingelsson M. Antibodies against
alpha-synuclein reduce oligomerization in living cells. PLoS One.
2011;6(10):e27230. doi: 10.1371/journal.pone.0027230. Epub 2011 Oct
31. PubMed
PMID: 22073131; PubMed Central PMCID: PMC3205056.

43: Badiola N, de Oliveira RM, Herrera F, Guardia-Laguarta C,

Gonçalves SA, Pera
M, Suárez-Calvet M, Clarimon J, Outeiro TF, Lleó A. Tau enhances α-
synuclein
aggregation and toxicity in cellular models of synucleinopathy. PLoS
One.
2011;6(10):e26609. doi: 10.1371/journal.pone.0026609. Epub 2011 Oct
24. PubMed
PMID: 22039514; PubMed Central PMCID: PMC3200341.

44: Martins M, Rosa A, Guedes LC, Fonseca BV, Gotovac K, Violante S,

Mestre T,
Coelho M, Rosa MM, Martin ER, Vance JM, Outeiro TF, Wang L,
Borovecki F, Ferreira
JJ, Oliveira SA. Convergence of miRNA expression profiling, α-
synuclein
interacton and GWAS in Parkinson's disease. PLoS One.
2011;6(10):e25443. doi:
10.1371/journal.pone.0025443. Epub 2011 Oct 7. PubMed PMID:
22003392; PubMed
Central PMCID: PMC3189215.

45: Swinnen E, Büttner S, Outeiro TF, Galas MC, Madeo F, Winderickx

J, Franssens
V. Aggresome formation and segregation of inclusions influence
toxicity of
α-synuclein and synphilin-1 in yeast. Biochem Soc Trans. 2011 Oct;
39(5):1476-81.
doi: 10.1042/BST0391476. Review. PubMed PMID: 21936837.

46: Outeiro TF. Amyloidogenesis: FlAsH illuminates Aβ aggregation.

Nat Chem Biol.
2011 Aug 17;7(9):581-2. doi: 10.1038/nchembio.636. PubMed PMID:
21849997.

47: Szego ÉM, Gerhardt E, Outeiro TF, Kermer P. Dopamine-depletion

and increased
α-synuclein load induce degeneration of cortical cholinergic fibers
in mice. J
Neurol Sci. 2011 Nov 15;310(1-2):90-5. doi: 10.1016/j.jns.
2011.06.048. Epub 2011
Jul 19. PubMed PMID: 21774947.

48: de Oliveira RM, Marijanovic Z, Carvalho F, Miltényi GM, Matos

JE, Tenreiro S,
Oliveira S, Enguita FJ, Stone R, Outeiro TF. Impaired proteostasis
contributes to
renal tubular dysgenesis. PLoS One. 2011;6(6):e20854. doi:
10.1371/journal.pone.0020854. Epub 2011 Jun 9. PubMed PMID:
21695262; PubMed
Central PMCID: PMC3111453.

49: Marques S, Batalha VL, Lopes LV, Outeiro TF. Modulating

Alzheimer's disease
through caffeine: a putative link to epigenetics. J Alzheimers Dis.
2011;24 Suppl
2:161-71. doi: 10.3233/JAD-2011-110032. Review. PubMed PMID:
21427489.

50: Jorge CD, Ventura R, Maycock C, Outeiro TF, Santos H, Costa J.

Assessment of
the efficacy of solutes from extremophiles on protein aggregation in
cell models
of Huntington's and Parkinson's diseases. Neurochem Res. 2011 Jun;
36(6):1005-11.
doi: 10.1007/s11064-011-0440-3. Epub 2011 Mar 17. PubMed PMID:
21416120.

51: Herrera F, Tenreiro S, Miller-Fleming L, Outeiro TF.

Visualization of
cell-to-cell transmission of mutant huntingtin oligomers. PLoS Curr.
2011 Feb
11;3:RRN1210. doi: 10.1371/currents.RRN1210. PubMed PMID: 21331289;
PubMed
Central PMCID: PMC3037516.

52: Hansen C, Angot E, Bergström AL, Steiner JA, Pieri L, Paul G,

Outeiro TF,
Melki R, Kallunki P, Fog K, Li JY, Brundin P. α-Synuclein propagates
from mouse
brain to grafted dopaminergic neurons and seeds aggregation in
cultured human
cells. J Clin Invest. 2011 Feb;121(2):715-25. doi: 10.1172/JCI43366.
Epub 2011
Jan 18. PubMed PMID: 21245577; PubMed Central PMCID: PMC3026723.

53: da Costa G, Guerreiro A, Correia CF, Gomes RJ, Freire A,

Monteiro E, Barroso
E, Coelho AV, Outeiro TF, Freire AP, Cordeiro C. A non-invasive
method based on
saliva to characterize transthyretin in familial amyloidotic
polyneuropathy
patients using FT-ICR high-resolution MS. Proteomics Clin Appl. 2010
Jul;4(6-7):674-8. PubMed PMID: 21179887.

54: Büttner S, Delay C, Franssens V, Bammens T, Ruli D, Zaunschirm

S, de Oliveira
RM, Outeiro TF, Madeo F, Buée L, Galas MC, Winderickx J. Synphilin-1
enhances
α-synuclein aggregation in yeast and contributes to cellular stress
and cell
death in a Sir2-dependent manner. PLoS One. 2010 Oct
27;5(10):e13700. doi:
10.1371/journal.pone.0013700. PubMed PMID: 21060871; PubMed Central
PMCID:
PMC2965147.

55: Tauber E, Miller-Fleming L, Mason RP, Kwan W, Clapp J, Butler

NJ, Outeiro TF,
Muchowski PJ, Giorgini F. Functional gene expression profiling in
yeast
implicates translational dysfunction in mutant huntingtin toxicity.
J Biol Chem.
2011 Jan 7;286(1):410-9. doi: 10.1074/jbc.M110.101527. Epub 2010 Nov
2. PubMed
PMID: 21044956; PubMed Central PMCID: PMC3012999.

56: Diógenes MJ, Outeiro TF. Neurotrophic factors as a protective

strategy in
Parkinson's disease. CNS Neurol Disord Drug Targets. 2010 Dec;9(6):
754-63.
Review. PubMed PMID: 20942787.
57: Kazantsev AG, Outeiro TF. Drug discovery for CNS disorders: from
bench to
bedside. CNS Neurol Disord Drug Targets. 2010 Dec;9(6):668. PubMed
PMID:
20942783.

58: de Oliveira RM, Pais TF, Outeiro TF. Sirtuins: common targets in
aging and in
neurodegeneration. Curr Drug Targets. 2010 Oct;11(10):1270-80.
Review. PubMed
PMID: 20840069.

59: Marques SC, Oliveira CR, Pereira CM, Outeiro TF. Epigenetics in
neurodegeneration: a new layer of complexity. Prog
Neuropsychopharmacol Biol
Psychiatry. 2011 Mar 30;35(2):348-55. doi: 10.1016/j.pnpbp.
2010.08.008. Epub 2010
Aug 22. Review. PubMed PMID: 20736041.

60: Tenreiro S, Outeiro TF. Simple is good: yeast models of

neurodegeneration.
FEMS Yeast Res. 2010 Dec;10(8):970-9. doi: 10.1111/j.
1567-1364.2010.00649.x.
Review. PubMed PMID: 20579105.

61: Gonçalves SA, Matos JE, Outeiro TF. Zooming into protein
oligomerization in
neurodegeneration using BiFC. Trends Biochem Sci. 2010 Nov;35(11):
643-51. doi:
10.1016/j.tibs.2010.05.007. Epub 2010 Jun 17. Review. PubMed PMID:
20561791.

62: Marques SC, Oliveira CR, Outeiro TF, Pereira CM. Alzheimer's
disease: the
quest to understand complexity. J Alzheimers Dis. 2010;21(2):373-83.
doi:
10.3233/JAD-2010-100303. Review. PubMed PMID: 20555132.

63: Nakhjavani M, Morteza A, Khajeali L, Esteghamati A, Khalilzadeh

O, Asgarani
F, Outeiro TF. Increased serum HSP70 levels are associated with the
duration of
diabetes. Cell Stress Chaperones. 2010 Nov;15(6):959-64. doi:
10.1007/s12192-010-0204-z. Epub 2010 May 23. PubMed PMID: 20496051;
PubMed
Central PMCID: PMC3024058.
64: Vicente Miranda H, Outeiro TF. The sour side of
neurodegenerative disorders:
the effects of protein glycation. J Pathol. 2010 May;221(1):13-25.
doi:
10.1002/path.2682. Review. PubMed PMID: 20186922.

65: Su LJ, Auluck PK, Outeiro TF, Yeger-Lotem E, Kritzer JA, Tardiff
DF,
Strathearn KE, Liu F, Cao S, Hamamichi S, Hill KJ, Caldwell KA, Bell
GW, Fraenkel
E, Cooper AA, Caldwell GA, McCaffery JM, Rochet JC, Lindquist S.
Compounds from
an unbiased chemical screen reverse both ER-to-Golgi trafficking
defects and
mitochondrial dysfunction in Parkinson's disease models. Dis Model
Mech. 2010
Mar-Apr;3(3-4):194-208. doi: 10.1242/dmm.004267. Epub 2009 Dec 28.
PubMed PMID:
20038714; PubMed Central PMCID: PMC2869493.

66: da Costa G, Gomes R, Correia CF, Freire A, Monteiro E, Martins

A, Barroso E,
Coelho AV, Outeiro TF, Ponces Freire A, Cordeiro C. Identification
and
quantitative analysis of human transthyretin variants in human serum
by Fourier
transform ion-cyclotron resonance mass spectrometry. Amyloid. 2009
Dec;16(4):201-7. doi: 10.3109/13506120903421561. PubMed PMID:
19922331.

67: Outeiro TF, Ferreira J. Current and future therapeutic

strategies for
Parkinson's disease. Curr Pharm Des. 2009;15(34):3968-76. PubMed
PMID: 19751203.

68: Outeiro TF, Klucken J, Bercury K, Tetzlaff J, Putcha P, Oliveira

LM, Quintas
A, McLean PJ, Hyman BT. Dopamine-induced conformational changes in
alpha-synuclein. PLoS One. 2009 Sep 4;4(9):e6906. doi:
10.1371/journal.pone.0006906. PubMed PMID: 19730729; PubMed Central
PMCID:
PMC2731858.

69: Mollenhauer B, Cullen V, Kahn I, Krastins B, Outeiro TF,

Pepivani I, Ng J,
Schulz-Schaeffer W, Kretzschmar HA, McLean PJ, Trenkwalder C,
Sarracino DA,
Vonsattel JP, Locascio JJ, El-Agnaf OM, Schlossmacher MG. Direct
quantification
of CSF alpha-synuclein by ELISA and first cross-sectional study in
patients with
neurodegeneration. Exp Neurol. 2008 Oct;213(2):315-25. doi:
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