Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

Group

Volume

Year

000075-07-0 Acetaldehyde associated with consumption of alcoholic

beverages
Acid mists, strong inorganic
001402-68-2 Aflatoxins
Alcoholic beverages
Aluminium production

100E

2012

1
1
1
1

2012
2012
2012
2012

000092-67-1 4-Aminobiphenyl

Areca nut
000313-67-7 Aristolochic acid
(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)
000313-67-7 Aristolochic acid, plants containing
007440-38-2 Arsenic and inorganic arsenic compounds

1
1

54, 100F
56, 82, 100F
44, 96, 100E
34, Sup 7,
100F
1, Sup 7, 99,
100F
85, 100E
82, 100A

82, 100A
23, Sup 7,
100C
14, Sup 7,
100C

2012
2012

2012

1
1
1

2012
2012
2012

2012

001332-21-4 Asbestos (all forms, including actinolite, amosite,

013768-00-8 anthophyllite, chrysotile, crocidolite, tremolite)
(NB: Mineral substances (e.g. talc or vermiculite) that
012172-73-5
contain asbestos should also be regarded as
017068-78-9 carcinogenic to humans.)
012001-29-5
012001-28-4
014567-73-8
Auramine production

000446-86-6 Azathioprine

000071-43-2 Benzene

000092-87-5 Benzidine

Benzidine, dyes metabolized to

(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)
000050-32-8 Benzo[a]pyrene
(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)
007440-41-7 Beryllium and beryllium compounds
Betel quid with tobacco
Betel quid without tobacco

Sup 7, 99,
100F
26, Sup 7,
100A
29, Sup 7.
100F
29, Sup 7,
99, 100F
99, 100F

92, 100F

2012

1
1
1

58, 100C
85, 100E
85, 100E

2012
2012
2012

2012
2012
2012
2012

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

Group

Volume

Year

000542-88-1 Bis(chloromethyl)ether; chloromethyl methyl ether

000107-30-2 (technical-grade)
000055-98-1 Busulfan

4, Sup 7,
100F

2012

2012

000106-99-0 1,3-Butadiene
007440-43-9 Cadmium and cadmium compounds
000305-03-3 Chlorambucil

1
1
1

000494-03-1 Chlornaphazine

018540-29-9 Chromium (VI) compounds

Clonorchis sinensis (infection with)
Coal, indoor emissions from household combustion of
Coal gasification
008007-45-2 Coal-tar distillation
065996-93-2 Coal-tar pitch

1
1
1
1
1
1

Coke production
000050-18-0 Cyclophosphamide
006055-19-2
059865-13-3 Cyclosporine
079217-60-0
000056-53-1 Diethylstilbestrol

1
1

4, Sup 7,
100A
97, 100F
58, 100C
26, Sup 7,
100A
4, Sup 7,
100A
49, 100C
61, 100B
95, 100E
92, 100F
92, 100F
35, Sup 7,
100F
92, 100F
26, Sup 7,
100A

50, 100A

2012

2012

Engine exhaust, diesel

Epstein-Barr virus
066733-21-9 Erionite

1
1
1

Estrogen therapy, postmenopausal

Estrogen-progestogen menopausal therapy (combined)
Estrogen-progestogen oral contraceptives (combined)
(NB: There is also convincing evidence in humans that
these agents confer a protective effect against cancer in
the endometrium and ovary)
000064-17-5 Ethanol in alcoholic beverages
000075-21-8 Ethylene oxide
(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)
033419-42-0 Etoposide
(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)

1
1
1

21, Sup 7,
100A
46, 105
70, 100B
42, Sup 7,
100C
72, 100A
72, 91, 100A
72, 91, 100A

1
1

96, 100E
97, 100F

2012
2012

76, 100A

2012

2012
2012
2012
2012
2012
2012
2012
2012
2012
2012
2012
2012

in prep
2012
2012
2012
2012
2012

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

Group

033419-42-0 Etoposide in combination with cisplatin and bleomycin

015663-27-1
011056-06-7
Fission products, including strontium-90
000050-00-0 Formaldehyde
Haematite mining (underground)
Helicobacter pylori (infection with)
Hepatitis B virus (chronic infection with)
Hepatitis C virus (chronic infection with)
Human immunodeficiency virus type 1 (infection with)
Human papillomavirus types 16, 18, 31, 33, 35, 39, 45,
51, 52, 56, 58, 59
(NB: The HPV types that have been classified as
carcinogenic to humans can differ by an order of
magnitude in risk for cervical cancer)
Human T-cell lymphotropic virus type I
Ionizing radiation (all types)
Iron and steel founding (occupational exposure during)

76, 100A

2012

1
1
1

100D
88, 100F
1, Sup 7,
100D
61, 100B
59, 100B
59, 100B
67, 100B
64, 90, 100B

2012
2012
2012

67, 100B
100D
34, Sup 7,
100F
Sup 7, 100F
70, 100B
100C
57, 99, 100F
9, Sup 7,
100A
24, Sup 7,
100A
57, 99, 100F

2012
2012
2012

1
1
1
1
1

1
1
1
1
1
1
1
1

000298-81-7 Methoxsalen (8-methoxypsoralen) plus ultraviolet A

radiation
000101-14-4 4,4'-Methylenebis(2-chloroaniline) (MOCA)
(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)
Mineral oils, untreated or mildly treated

MOPP and other combined chemotherapy including

alkylating agents
000091-59-8 2-Naphthylamine

Year

Isopropyl alcohol manufacture using strong acids

Kaposi sarcoma herpesvirus
Leather dust
Magenta production
000148-82-3 Melphalan

Neutron radiation
(NB: Overall evaluation upgraded to Group 1 with
supporting evidence from other relevant data)
Nickel compounds

Volume

33, Sup 7,
100F
Sup 7, 100A

2012
2012
2012
2012
2012

2012
2012
2012
2012
2012
2012
2012

2012
2012
2012

4, Sup 7, 99,
100F
75, 100D

49, 100C

2012

2012

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

Group

016543-55-8 N'-Nitrosonornicotine (NNN) and 4-(N064091-91-4 Nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK)

(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)
Opisthorchis viverrini (infection with)
Outdoor air pollution
Outdoor air pollution, particulate matter in
Painter (occupational exposure as a)
Particulate matter in outdoor air pollution (see Outdoor air
pollution, particulate matter in)
057465-28-8 3,4,5,3,4-Pentachlorobiphenyl (PCB-126)
(see Polychlorinated biphenyls, dioxin-like, with a TEF
according to WHO)
057117-31-4 2,3,4,7,8-Pentachlorodibenzofuran
(NB: Overall evaluation upgraded to Group 1 based on
mechanistic and other relevant data)
000062-44-2 Phenacetin
(NB: Overall evaluation upgraded to Group 1 with
supporting evidence from other relevant data)
Phenacetin, analgesic mixtures containing
014596-37-3 Phosphorus-32, as phosphate
007440-07-5 Plutonium
001336-36-3 Polychlorinated biphenyls

013233-32-4
013982-63-3
015262-20-1
010043-92-2

Polychlorinated biphenyls, dioxin-like, with a Toxicity

Equivalency Factor (TEF) according to WHO (PCBs 77,
81, 105, 114, 118, 123, 126, 156, 157, 167, 169, 189)
(NB: Overall evaluation upgraded to Group 1 with
strong supporting evidence from other relevant data)
Radioiodines, including iodine-131
Radionuclides, alpha-particle-emitting, internally
deposited
(NB: Specific radionuclides for which there is sufficient
evidence in humans are also listed individually as
Group 1 agents)
Radionuclides, beta-particle-emitting, internally deposited
(NB: Specific radionuclides for which there is sufficient
evidence in humans are also listed individually as
Group 1 agents)
Radium-224 and its decay products
Radium-226 and its decay products
Radium-228 and its decay products
Radon-222 and its decay products

Volume

Year

89, 100E

2012

1
1
1
1

61, 100B
109
109
47, 98, 100F

100F

2012

100F

2012

24, Sup 7,
100A

2012

1
1
1
1
1

Sup 7, 100A
78, 100D
78, 100D
18, Sup 7,
107
107

1
1

78, 100D
78, 100D

2012
2012

78, 100D

2012

1
1
1
1

78, 100D
78, 100D
78, 100D
43, 78, 100D

2012
2012
2012
2012

2012
in prep
in prep
2012

2012
2012
2012
in prep
in prep

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

Group

Rubber manufacturing industry

Salted fish, Chinese-style

Schistosoma haematobium (infection with)
013909-09-6 Semustine [1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1nitrosourea, Methyl-CCNU]
068308-34-9 Shale oils

1
1
1
1

014808-60-7 Silica dust, crystalline, in the form of quartz or cristobalite

Solar radiation
Soot (as found in occupational exposure of chimney
sweeps)
000505-60-2 Sulfur mustard

1
1
1

010540-29-1 Tamoxifen
(NB: There is also conclusive evidence that tamoxifen
reduces the risk of contralateral breast cancer in breast
cancer patients)
001746-01-6 2,3,7,8-Tetrachlorodibenzo-para-dioxin
000052-24-4 Thiotepa
007440-29-1 Thorium-232 and its decay products
Tobacco, smokeless
Tobacco smoke, second-hand
Tobacco smoking
000095-53-4 ortho-Toluidine
000299-75-2 Treosulfan

000079-01-6 Trichloroethylene
Ultraviolet radiation (wavelengths 100-400 nm,
encompassing UVA, UVB, and UVC)
Ultraviolet-emitting tanning devices
000075-01-4 Vinyl chloride
Wood dust
X- and Gamma-Radiation
000079-06-1 Acrylamide
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
023214-92-8 Adriamycin
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Androgenic (anabolic) steroids

1
1
1
1
1
1
1
1
1
1

Volume
28, Sup 7,
100F
56, 100E
61, 100B
Sup 7, 100A
35, Sup 7,
100F
68, 100C
55, 100D
35, Sup 7,
100F
9, Sup 7,
100F
66, 100A

69, 100F
50, 100A
78, 100D
89, 100E
83, 100E
83, 100E
77, 99, 100F
26, Sup 7,
100A
63, 106
100D

Year
2012
2012
2012
2012
2012
2012
2012
2012
2012
2012

2012
2012
2012
2012
2012
2012
2012
2012
in prep
2012

1
1
1
1
2A

100D
97, 100F
62, 100C
75, 100D
60

2012
2012
2012
2012
1994

2A

10, Sup 7

1987

2A

Sup 7

1987

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

000320-67-2

000154-93-8
064742-93-4
002425-06-1

000075-87-6
000302-17-0
000056-75-7

Agent

Group

Art glass, glass containers and pressed ware

(manufacture of)
Azacitidine
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Biomass fuel (primarily wood), indoor emissions from
household combustion of
Bischloroethyl nitrosourea (BCNU)
Bitumens, occupational exposure to oxidized bitumens
and their emissions during roofing
Captafol
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Carbon electrode manufacture
Chloral
Chloral hydrate
Chloramphenicol
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
alpha-Chlorinated toluenes (benzal chloride,
benzotrichloride, benzyl chloride) and benzoyl chloride
(combined exposures)

000098-87-3
000098-07-7
000100-44-7
000098-88-4
013010-47-4 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000095-69-2 4-Chloro-ortho-toluidine
054749-90-5 Chlorozotocin
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
015663-27-1 Cisplatin
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
007440-48-4 Cobalt metal with tungsten carbide
012070-12-1
008001-58-9 Creosotes
027208-37-3 Cyclopenta[cd]pyrene
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000224-42-0 Dibenz[a,j]acridine
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)

Volume

Year

2A

58

1993

2A

50

1990

2A

95

2010

2A
2A

26, Sup 7
103

1987
2013

2A

53

1991

2A
2A
2A
2A

92
63, 106
84, 106
50

2A

29, Sup 7, 71

1999

2A

26, Sup 7

1987

2A
2A

77, 99
50

2010
1990

2A

26, Sup 7

1987

2A

86

2006

2A
2A

92
92

2010
2010

2A

32, Sup 7,
103

2013

2010
in prep
in prep
1990

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

Group

000053-70-3 Dibenz[a,h]anthracene
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000191-30-0 Dibenzo[a,l]pyrene
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000064-67-5 Diethyl sulfate
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000079-44-7 Dimethylcarbamoyl chloride
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000540-73-8 1,2-Dimethylhydrazine
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000077-78-1 Dimethyl sulfate
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000106-89-8 Epichlorohydrin
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000051-79-6 Ethyl carbamate (Urethane)
000106-93-4 Ethylene dibromide
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000759-73-9 N-Ethyl-N-nitrosourea
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Frying, emissions from high-temperature
000556-52-5 Glycidol
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Hairdresser or barber (occupational exposure as a)
Human papillomavirus type 68
022398-80-7 Indium phosphide
(NB: Overall evaluation upgraded to Group 2A)
076180-96-6 IQ (2-Amino-3-methylimidazo[4,5-f]quinoline)
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Lead compounds, inorganic
Malaria (caused by infection with Plasmodium falciparum
in holoendemic areas)
Mate, hot

Volume

Year

2A

92

2010

2A

92

2010

2A

54, 71

1999

2A

12, Sup 7, 71

1999

2A

4, Sup 7, 71

1999

2A

4, Sup 7, 71

1999

2A

11, Sup 7, 71

1999

2A
2A

7, Sup 7, 96
15, Sup 7, 71

2010
1999

2A

17, Sup 7

1987

2A
2A

95
77

2010
2000

2A
2A
2A

57, 99
100B
86

2010
2012
2006

2A

56

1993

2A
2A

87
104

2006
2013

2A

51

1991

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

Group

Year

2A
2A

104
40, Sup 7

2013
1987

2A

7, Sup 7, 71

1999

2A

4, Sup 7

1987

2A

17, Sup 7

1987

2A

94

2010

2A
2A
2A
2A

46, 105
9, Sup 7
46, 105
17, Sup 7

in prep
1987
in prep
1987

2A

17, Sup 7

1987

2A

101

2013

2A

53

1991

2A
2A

45
108

1989
in prep

059536-65-1 Polybrominated biphenyls

(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data, namely
mechanistic similarity with polychlorinated biphenyls
classified in Group 1)

2A

41, Sup 7,
107

in prep

000366-70-1 Procarbazine hydrochloride

(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Shiftwork that involves circadian disruption
000096-09-3 Styrene-7,8-oxide
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)

2A

26, Sup 7

1987

2A
2A

98
60

2010
1994

000484-20-8

000066-27-3

000070-25-7

000684-93-5

007496-02-8
000051-75-2
005522-43-0
000055-18-5

000062-75-9

000088-72-2

111025-46-8

Merkel cell polyomavirus (MCV)

5-Methoxypsoralen
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Methyl methanesulfonate
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
N-Methyl-N-nitro-N-nitrosoguanidine (MNNG)
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
N-Methyl-N-nitrosourea
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Nitrate or nitrite (ingested) under conditions that result in
endogenous nitrosation
6-Nitrochrysene
Nitrogen mustard
1-Nitropyrene
N-Nitrosodiethylamine
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
N-Nitrosodimethylamine
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
2-Nitrotoluene
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
Non-arsenical insecticides (occupational exposures in
spraying and application of)
Petroleum refining (occupational exposures in)
Pioglitazone

Volume

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

Group

029767-20-2 Teniposide
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000127-18-4 Tetrachloroethylene (Perchloroethylene)
000096-18-4 1,2,3-Trichloropropane
000126-72-7 Tris(2,3-dibromopropyl) phosphate
(NB: Overall evaluation upgraded to Group 2A with
supporting evidence from other relevant data)
000593-60-2 Vinyl bromide
(NB: (1) Overall evaluation upgraded to Group 2A
based on mechanistic and other relevant data;
(2) For practical purposes, vinyl bromide should be
considered to act similarly to the human carcinogen
vinyl chloride.)
000075-02-5 Vinyl fluoride
(NB: (1) Overall evaluation upgraded to Group 2A
based on mechanistic and other relevant data;
(2) For practical purposes, vinyl fluoride should be
considered to act similarly to the human carcinogen
vinyl chloride.)
026148-68-5 A-alpha-C (2-Amino-9H-pyrido[2,3-b]indole)
000075-07-0 Acetaldehyde
000060-35-5 Acetamide
000107-13-1 Acrylonitrile
003688-53-7 AF-2 [2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide]
006795-23-9 Aflatoxin M1
Aloe vera, whole leaf extract
000060-09-3 para-Aminoazobenzene
000097-56-3 ortho-Aminoazotoluene
000081-49-2 1-Amino-2,4-dibromoanthraquinone
000712-68-5 2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole
051264-14-3 Amsacrine
000090-04-0 ortho-Anisidine
000084-65-1 Anthraquinone
001309-64-4 Antimony trioxide
000140-57-8 Aramite
000492-80-8 Auramine
000115-02-6 Azaserine
000151-56-4 Aziridine
(NB: Overall evaluation upgraded to Group 2B with
supporting evidence from other relevant data)

Volume

Year

2A

76

2A
2A
2A

63, 106
63
20, Sup 7, 71

2A

39, Sup 7,
71, 97

2008

2A

63, 97

2008

2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B

40, Sup 7
36, Sup 7, 71
7, Sup 7, 71
71
31, Sup 7
56
108
8, Sup 7
8, Sup 7
101
7, Sup 7
76
73
101
47
5, Sup 7
1, Sup 7, 99,
100F
10, Sup 7
9, Sup 7, 71

2B
2B

2000

in prep
1995
1999

1987
1999
1999
1999
1987
1993
in prep
1987
1987
2013
1987
2000
1999
2013
1989
1987
2012
1987
1999

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

Group

000202-33-5 Benz[j]aceanthrylene
(NB: Overall evaluation upgraded to Group 2B with
supporting mechanistic and other relevant data)
000056-55-3 Benz[a]anthracene
000205-99-2 Benzo[b]fluoranthene
000205-82-3 Benzo[j]fluoranthene
000207-08-9 Benzo[k]fluoranthene
000271-89-6 Benzofuran
000195-19-7 Benzo[c]phenanthrene
(NB: Overall evaluation upgraded to Group 2B with
supporting evidence from other relevant data)
000119-61-9 Benzophenone
001694-09-3 Benzyl violet 4B
003296-90-0 2,2-Bis(bromomethyl)propane-1,3-diol
Bitumens, occupational exposure to hard bitumens and
their emissions during mastic asphalt work
008052-42-4 Bitumens, occupational exposure to straight-run bitumens
064741-56-6 and their emissions during road paving
BK polyomavirus (BKV)
011056-06-7 Bleomycins
(NB: Overall evaluation upgraded to Group 2B with
supporting evidence from other relevant data)
Bracken fern
005589-96-8 Bromochloroacetic acid
000075-27-4 Bromodichloromethane
025013-16-5 Butylated hydroxyanisole (BHA)
003068-88-0 beta-Butyrolactone
000331-39-5 Caffeic acid
000086-74-8 Carbazole
001333-86-4 Carbon black
000056-23-5 Carbon tetrachloride
Carpentry and joinery
053973-98-1 Carrageenan, degraded (Poligeenan)
000120-80-9 Catechol
000057-74-9 Chlordane
000143-50-0 Chlordecone (Kepone)
000115-28-6 Chlorendic acid
Chlorinated paraffins of average carbon chain length C12
and average degree of chlorination approximately 60%

10

Volume

Year

2B

92

2010

2B
2B
2B
2B
2B
2B

92
92
92
92
63
92

2010
2010
2010
2010
1995
2010

2B
2B
2B
2B

101
16, Sup 7
77
103

2013
1987
2000
2013

2B

103

2013

2B
2B

104
26, Sup 7

2013
1987

2B
2B
2B
2B
2B
2B
2B

40, Sup 7
101
52, 71
40, Sup 7
11, Sup 7, 71
56
32, Sup 7,
71, 103
65, 93
20, Sup 7, 71
25, Sup 7
31, Sup 7
15, Sup 7, 71
79
20, Sup 7
48
48

1987
2013
1999
1987
1999
1993
2013

2B
2B
2B
2B
2B
2B
2B
2B
2B

2010
1999
1987
1987
1999
2001
1987
1990
1990

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

000106-47-8
077439-76-0
000067-66-3
000513-37-1

para-Chloroaniline
3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone
Chloroform
1-Chloro-2-methylpropene
Chlorophenoxy herbicides
4-Chloro-ortho-phenylenediamine
Chloroprene
Chlorothalonil
Chrysene
CI Acid Red 114
CI Basic Red 9
CI Direct Blue 15
Citrus Red No. 2
Cobalt and cobalt compounds
(NB: Evaluated as a group)
Cobalt metal without tungsten carbide
Cobalt sulfate and other soluble cobalt(II) salts
Coconut oil diethanolamine condensate
Coffee (urinary bladder)
(NB: There is some evidence of an inverse relationship
between coffee drinking and cancer of the large bowel;
coffee drinking could not be classified as to its
carcinogenicity to other organs)
para-Cresidine
Cumene
Cycasin
Dacarbazine
Dantron (Chrysazin; 1,8-Dihydroxyanthraquinone)
Daunomycin
DDT (4,4'-Dichlorodiphenyltrichloroethane)
N,N'-Diacetylbenzidine
2,4-Diaminoanisole
4,4'-Diaminodiphenyl ether
2,4-Diaminotoluene
Dibenz[a,h]acridine

000095-83-0
000126-99-8
001897-45-6
000218-01-9
006459-94-5
000569-61-9
002429-74-5
006358-53-8
007440-48-4
007440-48-4
010026-24-1
068603-42-9

000120-71-8
000098-82-8
014901-08-7
004342-03-4
000117-10-2
020830-81-3
000050-29-3
000613-35-4
000615-05-4
000101-80-4
000095-80-7
000226-36-8

Group

000224-53-3 Dibenz[c,h]acridine
(NB: Overall evaluation upgraded to Group 2B with
supporting evidence from other relevant data)

11

Volume

Year

2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B

57
84
73
63
41, Sup 7
27, Sup 7
71
73
92
57
57, 99
57
8, Sup 7
52

1993
2004
1999
1995
1987
1987
1999
1999
2010
1993
2010
1993
1987
1991

2B
2B
2B
2B

86
86
101
51

2006
2006
2013
1991

2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B

27, Sup 7
101
10, Sup 7
26, Sup 7
50
10, Sup 7
53
16, Sup 7
79
29, Sup 7
16, Sup 7
32, Sup 7,
103
103

1987
2013
1987
1987
1990
1987
1991
1987
2001
1987
1987
2013

2B

2013

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

Group

000194-59-2 7H-Dibenzo[c,g]carbazole

2B

000189-64-0
000189-55-9
000631-64-1
003252-43-5
000096-12-8
000096-13-9
000079-43-6
000106-46-7
000091-94-1
028434-86-8
000107-06-2
000075-09-2
000096-23-1
000542-75-6
000062-73-7

000111-42-2
000117-81-7
001615-80-1
000101-90-6
020830-75-5
000094-58-6
002973-10-6
000119-90-4
000060-11-7
025962-77-0
000087-62-7
000075-60-5
000119-93-7
000057-14-7
105735-71-5
022506-53-2
075321-20-9
042397-64-8

Dibenzo[a,h]pyrene
Dibenzo[a,i]pyrene
Dibromoacetic acid
Dibromoacetonitrile
1,2-Dibromo-3-chloropropane
2,3-Dibromopropan-1-ol
Dichloroacetic acid
para-Dichlorobenzene
3,3'-Dichlorobenzidine
3,3'-Dichloro-4,4'-diaminodiphenyl ether
1,2-Dichloroethane
Dichloromethane (Methylene chloride)
1,3-Dichloro-2-propanol
1,3-Dichloropropene (technical-grade)
Dichlorvos
Diesel fuel, marine
(NB: Overall evaluation upgraded to Group 2B with
supporting evidence from other relevant data)
Diethanolamine
Di(2-ethylhexyl)phthalate
1,2-Diethylhydrazine
Diglycidyl resorcinol ether
Digoxin
Dihydrosafrole
Diisopropyl sulfate
3,3'-Dimethoxybenzidine (ortho-Dianisidine)
para-Dimethylaminoazobenzene
trans-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2furyl)-vinyl]-1,3,4-oxadiazole
2,6-Dimethylaniline (2,6-Xylidine)
Dimethylarsinic acid
3,3'-Dimethylbenzidine (ortho-Tolidine)
1,1-Dimethylhydrazine
3,7-Dinitrofluoranthene
3,9-Dinitrofluoranthene
1,3-Dinitropyrene
1,6-Dinitropyrene

12

Volume

Year

2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B

32, Sup 7,
103
92
92
101
52, 71, 101
20, Sup 7, 71
77
84, 106
73
29, Sup 7
16, Sup 7
20, Sup 7, 71
71
101
41, Sup 7, 71
53
45

2013
2010
2010
2013
2013
1999
2000
in prep
1999
1987
1987
1999
1999
2013
1999
1991
1989

2B
2B
2B
2B
2B
2B
2B
2B
2B
2B

77, 101
77, 101
4, Sup 7, 71
36, Sup 7, 71
108
10, Sup 7
54, 71
4, Sup 7
8, Sup 7
7, Sup 7

2013
2013
1999
1999
in prep
1987
1999
1987
1987
1987

2B
2B
2B
2B
2B
2B
2B
2B

57
100C
1, Sup 7
4, Sup 7, 71
46, 65, 105
46, 65, 105
46, 105
46, 105

1993
2012
1987
1999
in prep
in prep
in prep
in prep

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

042397-65-9
000121-14-2
000606-20-2
000123-91-1
002475-45-8

1,8-Dinitropyrene
2,4-Dinitrotoluene
2,6-Dinitrotoluene
1,4-Dioxane
Disperse Blue 1
Dry cleaning (occupational exposures in)
Engine exhaust, gasoline
1,2-Epoxybutane
(NB: Overall evaluation upgraded to Group 2B with
supporting evidence from other relevant data)
Ethyl acrylate
Ethylbenzene
Ethyl methanesulfonate
Firefighter (occupational exposure as a)
2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole
Fuel oils, residual (heavy)
Fumonisin B1
Furan
Fusarium moniliforme, toxins derived from (fumonisin B1,
fumonisin B2, and fusarin C)
Gasoline
(NB: Overall evaluation upgraded to Group 2B with
supporting evidence from other relevant data)
Ginkgo biloba extract
Glu-P-1 (2-Amino-6-methyldipyrido[1,2-a:3',2'd]imidazole)
Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole)
Glycidaldehyde
Goldenseal root powder
Griseofulvin
HC Blue No. 1
Heptachlor
Hexachlorobenzene
Hexachlorocyclohexanes
Hexachloroethane
2,4-Hexadienal
Hexamethylphosphoramide
Human immunodeficiency virus type 2 (infection with)
Human papillomavirus types 5 and 8 (in patients with
epidermodysplasia verruciformis)

000106-88-7

000140-88-5
000100-41-4
000062-50-0
003570-75-0
116355-83-0
000110-00-9
116355-83-0

090045-36-6
067730-11-4
067730-10-3
000765-34-4
000126-07-8
002784-94-3
000076-44-8
000118-74-1
000067-72-1
000142-83-6
000680-31-9

Group

13

Volume

Year

2B
2B
2B
2B
2B
2B
2B
2B

46, 105
65
65
11, Sup 7, 71
48
63
46, 105
47, 71

in prep
1996
1996
1999
1990
1995
in prep
1999

2B
2B
2B
2B
2B
2B
2B
2B
2B

39, Sup 7, 71
77
7, Sup 7
98
7, Sup 7
45
82
63
56

1999
2000
1987
2010
1987
1989
2002
1995
1993

2B

45

1989

2B
2B

108
40, Sup 7

in prep
1987

2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B

40, Sup 7
11, Sup 7, 71
108
79
57
79
79
20, Sup 7
73
101
15, Sup 7, 71
67
100B

1987
1999
in prep
2001
1993
2001
2001
1987
1999
2013
1999
1996
2012

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

000302-01-2
000058-93-5
000129-43-1
000193-39-5
009004-66-4
000078-79-5
009000-38-8
000303-34-4
007439-92-1
000632-99-5
068006-83-7
000071-58-9
077094-11-2
077500-04-0
000531-76-0
000124-58-3
000075-55-8
000592-62-1
003697-24-3
000838-88-0
000101-77-9
000093-15-2
000693-98-1
000822-36-6
000108-10-1

Agent

Group

Human papillomavirus types 26, 53, 66, 67, 70, 73, 82

Human papillomavirus types 30, 34, 69, 85, 97
(NB: Classified by phylogenetic analogy to the HPV
genus alpha types classified in Group 1)
Hydrazine
Hydrochlorothiazide
1-Hydroxyanthraquinone
Indeno[1,2,3-cd]pyrene
Iron-dextran complex
Isoprene
JC polyomavirus (JCV)
Kava extract
Lasiocarpine
Lead
Magenta
Magnetic fields, extremely low-frequency
MeA-alpha-C (2-Amino-3-methyl-9H-pyrido[2,3-b]indole)
Medroxyprogesterone acetate
MeIQ (2-Amino-3,4-dimethylimidazo[4,5-f]quinoline)
MeIQx (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline)
Merphalan
Methylarsonic acid
2-Methylaziridine (Propyleneimine)
Methylazoxymethanol acetate
5-Methylchrysene
4,4'-Methylene bis(2-methylaniline)
4,4'-Methylenedianiline
Methyleugenol
2-Methylimidazole
4-Methylimidazole
Methyl isobutyl ketone
Methylmercury compounds
(NB: Evaluated as a group)
2-Methyl-1-nitroanthraquinone (uncertain purity)
N-Methyl-N-nitrosourethane

000129-15-7
000615-53-2
000098-83-9 -Methylstyrene
000056-04-2 Methylthiouracil
000443-48-1 Metronidazole

14

Volume

Year

2B
2B

100B
100B

2012
2012

2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B

4, Sup 7, 71
50, 108
82
92
2, Sup 7
60, 71
104
108
10, Sup 7
23, Sup 7
57, 99, 100F
80
40, Sup 7
21, Sup 7
56
56
9, Sup 7
100C
9, Sup 7, 71
10, Sup 7
92
4, Sup 7
39, Sup 7
101
101
101
101
58

2B
2B
2B

27, Sup 7
4, Sup 7
101

1987
1987
2013

2B
2B

79
13, Sup 7

2001
1987

1999
in prep
2002
2010
1987
1999
2013
in prep
1987
1987
2012
2002
1987
1987
1993
1993
1987
2012
1999
1987
2010
1987
1987
2013
2013
2013
2013
1993

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

Group

Volume

Year

000101-61-1 Michlers base [4,4-methylenebis(N,N-dimethyl)benzenamine]

000090-94-8 Michlers ketone [4,4-Bis(dimethylamino)benzophenone]

2B

27, Sup 7, 99

2010

2B

99

2010

101043-37-2
002385-85-5
000050-07-7
065271-80-9
000096-24-2
000315-22-0
003795-88-8

2B
2B
2B
2B
2B
2B
2B

94
20, Sup 7
10, Sup 7
76
101
10, Sup 7
7, Sup 7

2010
1987
1987
2000
2013
1987
1987

2B
2B
2B
2B
2B

24, Sup 7
82
49
13, Sup 7
73

1987
2002
1990
1987
1999

2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B

16, Sup 7
65
105
65
30, Sup 7
46, 105
7, Sup 7
7, Sup 7
9, Sup 7
77
29, Sup 7, 71
46, 105
17, Sup 7
17, Sup 7, 77
17, Sup 7
85
17, Sup 7
17, Sup 7
17, Sup 7
17, Sup 7
17, Sup 7
17, Sup 7

003771-19-5
000091-20-3
007440-02-0
000061-57-4
000139-13-9
000602-87-9
000091-23-6
017117-34-9
000098-95-3
001836-75-5
000607-57-8
000555-84-0
000531-82-8
000126-85-2
000075-52-5
000079-46-9
057835-92-4
000924-16-3
001116-54-7
000621-64-7
060153-49-3
010595-95-6
004549-40-0
000059-89-2
000100-75-4
000930-55-2
013256-22-9

Microcystin-LR
Mirex
Mitomycin C
Mitoxantrone
3-Monochloro-1,2-propanediol
Monocrotaline
5-(Morpholinomethyl)-3-[(5-nitrofurfurylidene)amino]-2oxazolidinone
Nafenopin
Naphthalene
Nickel, metallic and alloys
Niridazole
Nitrilotriacetic acid and its salts
(NB: Evaluated as a group)
5-Nitroacenaphthene
2-Nitroanisole
3-Nitrobenzanthrone
Nitrobenzene
Nitrofen (technical-grade)
2-Nitrofluorene
1-[(5-Nitrofurfurylidene)amino]-2-imidazolidinone
N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide
Nitrogen mustard N-oxide
Nitromethane
2-Nitropropane
4-Nitropyrene
N-Nitrosodi-n-butylamine
N-Nitrosodiethanolamine
N-Nitrosodi-n-propylamine
3-(N-Nitrosomethylamino)propionitrile
N-Nitrosomethylethylamine
N-Nitrosomethylvinylamine
N-Nitrosomorpholine
N-Nitrosopiperidine
N-Nitrosopyrrolidine
N-Nitrososarcosine

15

1987
1996
in prep
1996
1987
in prep
1987
1987
1987
2000
1999
in prep
1987
2000
1987
2004
1987
1987
1987
1987
1987
1987

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

000303-47-9
002646-17-5
000604-75-1
012174-11-7
000794-93-4
037319-17-8

Ochratoxin A
Oil Orange SS
Oxazepam
Palygorskite (Attapulgite) (long fibres, > 5 micrometres)
Panfuran S (containing dihydroxymethylfuratrizine)
Pentosan polysulfate sodium
Pickled vegetables (traditional in Asia)
Phenazopyridine hydrochloride
Phenobarbital
Phenolphthalein
Phenoxybenzamine hydrochloride
Phenyl glycidyl ether
Phenytoin
PhIP (2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine)
Polychlorophenols and their sodium salts (mixed
exposures)
Ponceau 3R
Ponceau MX
Potassium bromate
Primidone
Printing processes (occupational exposures in)
Progestins
Progestogen-only contraceptives
1,3-Propane sultone
beta-Propiolactone
Propylene oxide
Propylthiouracil
Pulegone
Radiofrequency electromagnetic fields1
Refractory ceramic fibres
Riddelliine
Safrole
Schistosoma japonicum (infection with)
Sodium ortho-phenylphenate
Special-purpose fibres such as E-glass and '475' glass
fibres
Sterigmatocystin

000136-40-3
000050-06-6
000077-09-8
000063-92-3
000122-60-1
000057-41-0
105650-23-5

003564-09-8
003761-53-3
007758-01-2
000125-33-7

001120-71-4
000057-57-8
000075-56-9
000051-52-5
000089-82-7

023246-96-0
000094-59-7
000132-27-4

010048-13-2
1

Group

Includes radiofrequency electromagnetic fields from wireless phones

16

Volume

Year

2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B

56
8, Sup 7
66
68
24, Sup 7
108
56
24, Sup 7
79
76
24, Sup 7
47, 71
66
56
53, 71

1993
1987
1996
1997
1987
in prep
1993
1987
2001
2000
1987
1999
1996
1993
1999

2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B

8, Sup 7
8, Sup 7
73
108
65
Sup 7
72
4, Sup 7, 71
4, Sup 7, 71
60
79
108
102
43, 81
10, Sup 7, 82
10, Sup 7
61
73
81

1987
1987
1999
in prep
1996
1987
1999
1999
1999
1994
2001
in prep
2013
2002
2002
1987
1994
1999
2002

2B

10, Sup 7

1987

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

Group

018883-66-4
000100-42-5
000095-06-7
000599-79-1

Volume

Year

Streptozotocin
Styrene
Sulfallate
Sulfasalazine
Surgical implants and other foreign bodies:
- Polymeric implants prepared as thin smooth film (with
the exception of poly(glycolic acid))
- Metallic implants prepared as thin smooth films
- Implanted foreign bodies of metallic cobalt, metallic
nickel and an alloy powder containing 66-67% nickel,
13-16% chromium and 7% iron
014807-96-6 Talc-based body powder (perineal use of)
000630-20-6 1,1,1,2-Tetrachloroethane

2B
2B
2B
2B
2B

17, Sup 7
60, 82
30, Sup 7
108
74

1987
2002
1987
in prep
1999

2B
2B

2010
in prep

000079-34-5 1,1,2,2-Tetrachloroethane

2B

000116-14-3 Tetrafluoroethylene
000509-14-8 Tetranitromethane
Textile manufacturing industry (work in)
000062-55-5 Thioacetamide
000139-65-1 4,4'-Thiodianiline
000141-90-2 Thiouracil
013463-67-7 Titanium dioxide
026471-62-5 Toluene diisocyanates
008001-35-2 Toxaphene (Polychlorinated camphenes)
000396-01-0 Triamterene
000817-09-4 Trichlormethine (Trimustine hydrochloride)
000076-03-9 Trichloroacetic acid
062450-06-0 Trp-P-1 (3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole)
062450-07-1 Trp-P-2 (3-Amino-1-methyl-5H-pyrido[4,3-b]indole)
000072-57-1 Trypan blue
000066-75-1 Uracil mustard
001314-62-1 Vanadium pentoxide
000108-05-4 Vinyl acetate
000100-40-3 4-Vinylcyclohexene
000106-87-6 4-Vinylcyclohexene diepoxide
Welding fumes
(NB: Volume 100D concluded that there is sufficient
evidence for ocular melanoma in welders)
007481-89-2 Zalcitabine

2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B
2B

93
41, Sup 7,
71, 106
20, Sup 7,
71, 106
19, Sup 7, 71
65
48
7, Sup 7
27, Sup 7
79
47, 93
39, Sup 7, 71
79
108
50
84, 106
31, Sup 7
31, Sup 7
8, Sup 7
9, Sup 7
86
63
60
60
49

2B

76

17

in prep
1999
1996
1990
1987
1987
2001
2010
1999
2001
in prep
1990
in prep
1987
1987
1987
1987
2006
1995
1994
1994
1990

2000

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

030516-87-1
000083-32-9
025732-74-5
059277-89-3
000494-38-2
008018-07-3
000107-02-8
000079-10-7

Zidovudine (AZT)
Acenaphthene
Acepyrene (3,4-dihydrocyclopenta[cd]pyrene)
Aciclovir
Acridine orange
Acriflavinium chloride
Acrolein
Acrylic acid
Acrylic fibres
Acrylonitrile-butadiene-styrene copolymers
Actinomycin D
Agaritine
Aldicarb
Aldrin
Allyl chloride
Allyl isothiocyanate
Allyl isovalerate
Amaranth
5-Aminoacenaphthene
2-Aminoanthraquinone
para-Aminobenzoic acid
1-Amino-2-methylanthraquinone
2-Amino-4-nitrophenol
2-Amino-5-nitrophenol
4-Amino-2-nitrophenol
2-Amino-5-nitrothiazole
11-Aminoundecanoic acid
Amitrole
(NB: Overall evaluation downgraded to Group 3 with
supporting evidence from other relevant data)
Ampicillin
Anaesthetics, volatile
Angelicin plus ultraviolet A radiation
Aniline
para-Anisidine
Anthanthrene
Anthracene
Anthranilic acid
Antimony trisulfide

000050-76-0
002757-90-6
000116-06-3
000309-00-2
000107-05-1
000057-06-7
002835-39-4
000915-67-3
004657-93-6
000117-79-3
000150-13-0
000082-28-0
000099-57-0
000121-88-0
000119-34-6
000121-66-4
002432-99-7
000061-82-5

000069-53-4
000523-50-2
000062-53-3
000104-94-9
000191-26-4
000120-12-7
000118-92-3
001345-04-6

Group

18

2B
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3

3
3
3
3
3
3
3
3
3

Volume

Year

76
92
92
76
16, Sup 7
13, Sup 7
63
19, Sup 7, 71
19, Sup 7
19, Sup 7
10, Sup 7
31, Sup 7
53
5, Sup 7
36, Sup 7, 71
73
36, Sup 7, 71
8, Sup 7
16, Sup 7
27, Sup 7
16, Sup 7
27, Sup 7
57
57
16, Sup 7
31, Sup 7
39, Sup 7
79

2000
2010
2010
2000
1987
1987
1995
1999
1987
1987
1987
1987
1991
1987
1999
1999
1999
1987
1987
1987
1987
1987
1993
1993
1987
1987
1987
2001

50
11, Sup 7
40, Sup 7
27, Sup 7
27, Sup 7
92
92
16, Sup 7
47

1990
1987
1987
1987
1987
2010
2010
1987
1989

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

Group

Volume

000052-46-0 Apholate
024938-64-5 para-Aramid fibrils
064436-13-1 Arsenobetaine and other organic arsenic compounds that
are not metabolized in humans
001912-24-9 Atrazine
(NB: Overall evaluation downgraded to Group 3 with
supporting evidence from other relevant data)
012192-57-3 Aurothioglucose
001072-52-2 2-(1-Aziridinyl)ethanol
000800-24-8 Aziridyl benzoquinone
000103-33-3 Azobenzene
000202-94-8 11H-Benz[bc]aceanthrylene
000211-91-6 Benz[l]aceanthrylene
000225-11-6 Benz[a]acridine

3
3
3

9, Sup 7
68
100C

1987
1997
2012

73

1999

3
3
3
3
3
3
3

1987
1987
1987
1987
2010
2010
2013

000225-51-4 Benz[c]acridine

000214-17-5
000196-78-1
000203-33-8
000203-12-3
000238-84-6
000243-17-4
000205-12-9
000239-35-0
000191-24-2
000192-97-2
000105-11-3
000094-36-0
000140-11-4
002168-68-5
000111-44-4
013483-18-6
056894-91-8
000108-60-1
002386-90-5
001675-54-3

3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3

13, Sup 7
9, Sup 7
9, Sup 7
8, Sup 7
92
92
32, Sup 7,
103
32, Sup 7,
103
92
92
92
92
92
92
92
103
92
92
29, Sup 7, 71
36, Sup 7, 71
40, Sup 7, 71
9, Sup 7
9, Sup 7, 71
15; Sup 7, 71
15; Sup 7, 71
41, Sup 7, 71
47, 71
47, 71
54
16, Sup 7

Benzo[b]chrysene
Benzo[g]chrysene
Benzo[a]fluoranthene
Benzo[ghi]fluoranthene
Benzo[a]fluorene
Benzo[b]fluorene
Benzo[c]fluorene
Benzo[b]naphtho[2,1-d]thiophene
Benzo[ghi]perylene
Benzo[e]pyrene
para-Benzoquinone dioxime
Benzoyl peroxide
Benzyl acetate
Bis(1-aziridinyl)morpholinophosphine sulfide
Bis(2-chloroethyl)ether
1,2-Bis(chloromethoxy)ethane
1,4-Bis(chloromethoxymethyl)benzene
Bis(2-chloro-1-methylethyl)ether
Bis(2,3-epoxycyclopentyl)ether
Bisphenol A diglycidyl ether (Araldite )
Bisulfites
000129-17-9 Blue VRS

19

Year

2013
2010
2010
2010
2010
2010
2010
2010
2013
2010
2010
1999
1999
1999
1987
1999
1999
1999
1999
1999
1999
1992
1987

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

003844-45-9
083463-62-1
000074-96-4
000075-25-2
000111-76-2
057018-52-7
000141-32-2
000128-37-0
000085-68-7
000096-48-0
000058-08-2

Brilliant Blue FCF, disodium salt

Bromochloroacetonitrile
Bromoethane
Bromoform
2-Butoxyethanol
1-tert-Butoxypropan-2-ol
n-Butyl acrylate
Butylated hydroxytoluene (BHT)
Butyl benzyl phthalate
gamma-Butyrolactone
Caffeine
Calcium carbide production
Cantharidin
Captan
Carbaryl
3-Carbethoxypsoralen
Carmoisine
Carrageenan, native
Chloramine
Chlordimeform
Chlorinated drinking-water
Chloroacetonitrile
Chlorobenzilate
Chlorodibromomethane
Chlorodifluoromethane
Chloroethane
Chlorofluoromethane
3-Chloro-2-methylpropene
Chloronitrobenzenes

3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3

16, Sup 7
52, 71
52, 71
52, 71
88
88
39, Sup 7, 71
40, Sup 7
73
11, Sup 7, 71
51
92
10, Sup 7
30, Sup 7
12, Sup 7
40, Sup 7
8, Sup 7
31, Sup 7
84
30, Sup 7
52
52, 71
30, Sup 7
52, 71
41, Sup 7, 71
52, 71
41, Sup 7, 71
63
65

1987
1999
1999
1999
2006
2006
1999
1987
1999
1999
1991
2010
1987
1987
1987
1987
1987
1987
2004
1987
1991
1999
1987
1999
1999
1999
1999
1995
1996

4-Chloro-meta-phenylenediamine
Chloropropham
Chloroquine
5-Chloro-ortho-toluidine
2-Chloro-1,1,1-trifluoroethane
Cholesterol
Chromium, metallic

3
3
3
3
3
3
3

27, Sup 7
12, Sup 7
13, Sup 7
77, 99
41, Sup 7, 71
31, Sup 7
49

1987
1987
1987
2010
1999
1987
1990

000056-25-7
000133-06-2
000063-25-2
020073-24-9
003567-69-9
009000-07-1
010599-90-3
006164-98-3
000107-14-2
000510-15-6
000124-48-1
000075-45-6
000075-00-3
000593-70-4
000563-47-3
000088-73-3
000121-73-3
000100-00-5
005131-60-2
000101-21-3
000054-05-7
000095-79-4
000075-88-7
000057-88-5
007440-47-3

Group

20

Volume

Year

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

016065-83-1
000532-82-1
006373-74-6
000523-44-4
001936-15-8
002425-85-6
051481-61-9
000087-29-6
000518-75-2
000637-07-0
000050-41-9

Chromium (III) compounds

Chrysoidine
CI Acid Orange 3
CI Acid Orange 20
CI Orange G
CI Pigment Red 3
Cimetidine
Cinnamyl anthranilate
Citrinin
Clofibrate
Clomiphene citrate
Coal dust
Copper 8-hydroxyquinoline
Coronene
Coumarin
meta-Cresidine
Crotonaldehyde
Crude oil
Cyclamates (sodium cyclamate)
Cyclochlorotine
Cyclohexanone
4H-Cyclopenta[def]chrysene
5,6-Cyclopenteno-1,2-benzanthracene
D & C Red No. 9
Dapsone
Decabromodiphenyl oxide
Deltamethrin
Diacetylaminoazotoluene
Diallate
1,2-Diamino-4-nitrobenzene
1,4-Diamino-2-nitrobenzene
2,5-Diaminotoluene
Diazepam
Diazomethane
Dibenz[a,c]anthracene
Dibenz[a,j]anthracene
Dibenzo-para-dioxin
Dibenzo[a,e]fluoranthene

010380-28-6
000191-07-1
000091-64-5
000102-50-1
004170-30-3
008002-05-9
000139-05-9
012663-46-6
000108-94-1
000202-98-2
007099-43-6
005160-02-1
000080-08-0
001163-19-5
052918-63-5
000083-63-6
002303-16-4
000099-56-9
005307-14-2
000095-70-5
000439-14-5
000334-88-3
000215-58-7
000224-41-9
000262-12-4
005385-75-1

Group

21

3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3

Volume
49
8, Sup 7
57
8, Sup 7
8, Sup 7
57
50
77
40, Sup 7
66
21, Sup 7
68
15, Sup 7
32, Sup 7
77
27, Sup 7
63
45
73
10, Sup 7
47, 71
92
92
57
24, Sup 7
48, 71
53
8, Sup 7
30, Sup 7
16, Sup 7
57
16, Sup 7
66
7, Sup 7
92
92
69
92

Year
1990
1987
1993
1987
1987
1993
1990
2000
1987
1996
1987
1997
1987
1987
2000
1987
1995
1989
1999
1987
1999
2010
2010
1993
1987
1999
1991
1987
1987
1987
1993
1987
1996
1987
2010
2010
1997
2010

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

000207-83-0
000192-47-2
000192-65-4
000192-51-8
000132-65-0
003018-12-0
007572-29-4
000541-73-1
000095-50-1
000110-57-6
000609-20-1
000078-87-5
000115-32-2
069655-05-6
000060-57-1

13H-Dibenzo[a,g]fluorene
Dibenzo[h,rst]pentaphene
Dibenzo[a,e]pyrene
Dibenzo[e,l]pyrene
Dibenzothiophene
Dichloroacetonitrile
Dichloroacetylene
meta-Dichlorobenzene
ortho-Dichlorobenzene
trans-1,4-Dichlorobutene
2,6-Dichloro-para-phenylenediamine
1,2-Dichloropropane
Dicofol
Didanosine
Dieldrin
Diesel fuels, distillate (light)
Di(2-ethylhexyl) adipate
N,N'-Diethylthiourea
Dihydroaceanthrylene
Dihydroxymethylfuratrizine (see also Panfuran S)
Dimethoxane
3,3'-Dimethoxybenzidine-4,4'-diisocyanate
para-Dimethylaminoazobenzenediazo sodium sulfonate
4,4'-Dimethylangelicin plus ultraviolet A radiation
4,5'-Dimethylangelicin plus ultraviolet A radiation
N,N-Dimethylaniline
Dimethylformamide
Dimethyl hydrogen phosphite
1,4-Dimethylphenanthrene
Dinitrosopentamethylenetetramine
3,5-Dinitrotoluene
2,4'-Diphenyldiamine
Disperse Yellow 3
Disulfiram
Dithranol
Doxefazepam
Doxylamine succinate
Droloxifene

000103-23-1
000105-55-5
000641-48-5
000794-93-4
000828-00-2
000091-93-0
000140-56-7
022975-76-4
004063-41-6
000121-69-7
000068-12-2
000868-85-9
022349-59-3
000101-25-7
000618-85-9
000492-17-1
002832-40-8
000097-77-8
001143-38-0
040762-15-0
000562-10-7
082413-20-5

Group

22

3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3

Volume
92
92
92
92
103
52, 71
39, Sup 7, 71
73
73
15, Sup 7, 71
39, Sup 7
41, Sup 7, 71
30, Sup 7
76
5, Sup 7
45
77
79
92
24, Sup 7
15, Sup 7
39, Sup 7
8, Sup 7
Sup 7
Sup 7
57
47, 71
48, 71
92
11, Sup 7
65
16, Sup 7
48
12, Sup 7
13; Sup 7
66
79
66

Year
2010
2010
2010
2010
2013
1999
1999
1999
1999
1999
1987
1999
1987
2000
1987
1989
2000
2001
2010
1987
1987
1987
1987
1987
1987
1993
1999
1999
2010
1987
1996
1987
1990
1987
1987
1996
2001
1996

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

Group

000150-69-6 Dulcin
Electric fields, extremely low-frequency
Electric fields, static
000072-20-8 Endrin
015086-94-9 Eosin
000141-37-7 3,4-Epoxy-6-methylcyclohexylmethyl-3,4-epoxy-6methylcyclo-hexanecarboxylate
024560-98-3 cis-9,10-Epoxystearic acid
029975-16-4 Estazolam
000536-33-4 Ethionamide
000074-85-1 Ethylene
000420-12-2 Ethylene sulfide
000096-45-7 Ethylenethiourea
(NB: Overall evaluation downgraded to Group 3 with
supporting evidence from other relevant data)
000103-11-7 2-Ethylhexyl acrylate
005456-28-0 Ethyl selenac
020941-65-5 Ethyl tellurac
000097-53-0 Eugenol
000314-13-6 Evans blue
002353-45-9 Fast Green FCF
051630-58-1 Fenvalerate
014484-64-1 Ferbam
001309-37-1 Ferric oxide
Flat-glass and specialty glass (manufacture of)
002164-17-2 Fluometuron
000206-44-0 Fluoranthene
000086-73-7 Fluorene
Fluorescent lighting
016984-48-8 Fluorides (inorganic, used in drinking-water)
000051-21-8 5-Fluorouracil
Fuel oils, distillate (light)
000067-45-8 Furazolidone
000098-01-1 Furfural
000054-31-9 Furosemide (Frusemide)
Fusarium graminearum, F. culmorum, and F.
crookwellense, toxins derived from (zearalenone,
deoxynivalenol, nivalenol, and fusarenone X)
Fusarium sporotrichioides, toxins derived from (T-2 toxin)

23

Volume

Year

3
3
3
3
3
3

12, Sup 7
80
80
5, Sup 7
15, Sup 7
11, Sup 7, 71

1987
2002
2002
1987
1987
1999

3
3
3
3
3
3

11, Sup 7, 71
66
13, Sup 7
60
11, Sup 7
79

1999
1996
1987
1994
1987
2001

3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3

60
12, Sup 7
12, Sup 7
36, Sup 7
8, Sup 7
16, Sup 7
53
12, Sup 7
1, Sup 7
58
30, Sup 7
92
92
55
27, Sup 7
26, Sup 7
45
31, Sup 7
63
50
56

1994
1987
1987
1987
1987
1987
1991
1987
1987
1993
1987
2010
2010
1992
1987
1987
1989
1987
1995
1990
1993

56

1993

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

Group

025812-30-0 Gemfibrozil
Glass filament, continuous
005431-33-4 Glycidyl oleate
007460-84-6 Glycidyl stearate
004680-78-8 Guinea Green B
016568-02-8 Gyromitrin
001317-60-8 Haematite
Hair colouring products (personal use of)
033229-34-4 HC Blue No. 2
002871-01-4 HC Red No. 3
059820-43-8 HC Yellow No. 4
Hepatitis D virus
000087-68-3 Hexachlorobutadiene
000070-30-4 Hexachlorophene
Human papillomavirus genus beta (except types 5 and 8)
and genus gamma
Human papillomavirus types 6 and 11
Human T-cell lymphotropic virus type II
023255-93-8 Hycanthone mesylate
000086-54-4 Hydralazine
007647-01-0 Hydrochloric acid
007722-84-1 Hydrogen peroxide
000123-31-9 Hydroquinone
001689-82-3 4-Hydroxyazobenzene
000148-24-3 8-Hydroxyquinoline
026782-43-4 Hydroxysenkirkine
000127-07-1 Hydroxyurea
Hypochlorite salts
Insulation glass wool
009004-51-7 Iron-dextrin complex
001338-16-5 Iron sorbitol-citric acid complex
015503-86-3 Isatidine
000054-85-3 Isonicotinic acid hydrazide (Isoniazid)
003778-73-2 Isophosphamide
000067-63-0 Isopropyl alcohol
Isopropyl oils
000120-58-1 Isosafrole
006870-67-3 Jacobine

24

Volume

Year

3
3
3
3
3
3
3
3
3
3
3
3
3
3
3

66
43, 81
11, Sup 7
11, Sup 7
16, Sup 7
31, Sup 7
1, Sup 7
57, 99
57
57
57
59
73
20, Sup 7
90, 100B

1996
2002
1987
1987
1987
1987
1987
2010
1993
1993
1993
1994
1999
1987
2012

3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3

90, 100B
67
13, Sup 7
24, Sup 7
54
36, Sup 7, 71
15, Sup 7, 71
8, Sup 7
13, Sup 7
10, Sup 7
76
52
43, 81
2, Sup 7
2, Sup 7
10, Sup 7
4, Sup 7
26, Sup 7
15, Sup 7, 71
15, Sup 7, 71
10, Sup 7
10, Sup 7

2012
1996
1987
1987
1992
1999
1999
1987
1987
1987
2000
1991
2002
1987
1987
1987
1987
1987
1999
1999
1987
1987

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

000520-18-3
000501-30-4
000105-74-8

005141-20-8
005989-27-5

021884-44-6

000121-75-5
000123-33-1
000542-78-9
012427-38-2
000551-74-6
013045-94-8
000108-78-1

000050-44-2
007439-97-6
000060-56-0
000059-05-2
000072-43-5
000096-33-3
073459-03-7
000074-83-9
001634-04-4

Agent

Group

Jet fuel
Kaempferol
Kojic acid
Lauroyl peroxide
Lead compounds, organic
(NB: Organic lead compounds are metabolized at least
in part, to ionic lead both in humans and animals. To the
extent that ionic lead, generated from organic lead, is
present in the body, it will be expected to exert the
toxicities associated with inorganic lead.)
Leather goods manufacture
Leather tanning and processing
Light Green SF
d-Limonene
(NB: Overall evaluation downgraded to Group 3 with
supporting evidence from other relevant data)
Lumber and sawmill industries (including logging)
Luteoskyrin
Madder root (Rubia tinctorum)
Magnetic fields, static
Malathion
Maleic hydrazide
Malonaldehyde
Maneb
Mannomustine dihydrochloride
Mate
Medphalan
Melamine
(NB: Overall evaluation downgraded to Group 3 with
supporting evidence from other relevant data)
6-Mercaptopurine
Mercury and inorganic mercury compounds
Metabisulfites
Methimazole
Methotrexate
Methoxychlor
Methyl acrylate
5-Methylangelicin plus ultraviolet A radiation
Methyl bromide
Methyl tert-butyl ether

25

Volume

Year

3
3
3
3
3

45
31, Sup 7
79
36, Sup 7, 71
23, Sup 7, 87

1989
1987
2001
1999
2006

3
3
3
3

25, Sup 7
25, Sup 7
16, Sup 7
73

1987
1987
1987
1999

3
3
3
3
3
3
3
3
3
3
3
3

25, Sup 7
10, Sup 7
82
80
30, Sup 7
4, Sup 7
36, Sup 7, 71
12, Sup 7
9, Sup 7
51
9, Sup 7
73

1987
1987
2002
2002
1987
1987
1999
1987
1987
1991
1987
1999

3
3
3
3
3
3
3
3
3
3

26, Sup 7
58
54
79
26, Sup 7
20, Sup 7
39, Sup 7, 71
Sup 7
41, Sup 7, 71
73

1987
1993
1992
2001
1987
1987
1999
1987
1999
1999

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

000598-55-0
000074-87-3
003351-28-8
003351-32-4
003351-31-3
003351-30-2
001705-85-7
000099-80-9
007220-79-3
000101-68-8
033543-31-6
001706-01-0
000078-98-8
000074-88-4
000080-62-6
090456-67-0
000298-00-0
000832-69-9
085878-63-3
000493-52-7
000144-34-3

Methyl carbamate
Methyl chloride
1-Methylchrysene
2-Methylchrysene
3-Methylchrysene
4-Methylchrysene
6-Methylchrysene
N-Methyl-N,4-dinitrosoaniline
Methylene blue
4,4'-Methylenediphenyl diisocyanate
2-Methylfluoranthene
3-Methylfluoranthene
Methylglyoxal
Methyl iodide
Methyl methacrylate
N-Methylolacrylamide
Methyl parathion
1-Methylphenanthrene
7-Methylpyrido[3,4-c]psoralen
Methyl red
Methyl selenac
Microcystis extracts
Mineral oils, highly-refined
Modacrylic fibres
Monuron
Morpholine
Musk ambrette
Musk xylene
1,5-Naphthalenediamine
1,5-Naphthalene diisocyanate
Naphtho[1,2-b]fluoranthene
Naphtho[2,1-a]fluoranthene
Naphtho[2,3-e]pyrene
1-Naphthylamine
1-Naphthylthiourea (ANTU)
Nithiazide
5-Nitro-ortho-anisidine
9-Nitroanthracene

000150-68-5
000110-91-8
000083-66-9
000081-15-2
002243-62-1
003173-72-6
111189-32-3
000203-20-3
000193-09-9
000134-32-7
000086-88-4
000139-94-6
000099-59-2
000602-60-8

Group

26

3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3

Volume

Year

12, Sup 7
41, Sup 7, 71
92
92
92
92
92
1, Sup 7
108
19, Sup 7, 71
92
92
51
41, Sup 7, 71
60
60
30, Sup 7
92
40, Sup 7
8, Sup 7
12, Sup 7
94
33, Sup 7
19, Sup 7
53
47, 71
65
65
27, Sup 7
19, Sup 7, 71
92
92
92
4, Sup 7
30, Sup 7
31, Sup 7
27, Sup 7
33, Sup 7

1987
1999
2010
2010
2010
2010
2010
1987
in prep
1999
2010
2010
1991
1999
1994
1994
1987
2010
1987
1987
1987
2010
1987
1987
1991
1999
1996
1996
1987
1999
2010
2010
2010
1987
1987
1987
1987
1987

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

020268-51-3
063041-90-7
000092-93-3
000892-21-7
000059-87-0
000067-20-9
000086-57-7
000581-89-5
020589-63-3
000789-07-1
037620-20-5
071267-22-6
000086-30-6
000156-10-5
029291-35-8
055557-01-2
055557-02-3
030310-80-6
085502-23-4
007519-36-0
000099-08-1
000099-99-0
000099-55-8
000804-36-4
118399-22-7
025038-54-4
022966-79-6

7-Nitrobenz[a]anthracene
6-Nitrobenzo[a]pyrene
4-Nitrobiphenyl
3-Nitrofluoranthene
Nitrofural (Nitrofurazone)
Nitrofurantoin
1-Nitronaphthalene
2-Nitronaphthalene
3-Nitroperylene
2-Nitropyrene
N'-Nitrosoanabasine (NAB)
N'-Nitrosoanatabine (NAT)
N-Nitrosodiphenylamine
para-Nitrosodiphenylamine
N-Nitrosofolic acid
N-Nitrosoguvacine
N-Nitrosoguvacoline
N-Nitrosohydroxyproline
3-(N-Nitrosomethylamino)propionaldehyde
N-Nitrosoproline
Nitrotoluenes

3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3

46
46
4, Sup 7
33, Sup 7
50
50
46
46
46
46
37, Sup 7, 89
37, Sup 7, 89
27, Sup 7
27, Sup 7
17, Sup 7
85
85
17, Sup 7
85
17, Sup 7
65

1989
1989
1987
1987
1990
1990
1989
1989
1989
1989
2007
2007
1987
1987
1987
2004
2004
1987
2004
1987
1996

5-Nitro-ortho-toluidine
Nitrovin
Nodularins
Nylon 6
Oestradiol mustard
Opisthorchis felineus (infection with)
Oxyphenbutazone
Paint manufacture (occupational exposure in)
Palygorskite (Attapulgite)(short fibres, < 5 micrometres)
Paracetamol (Acetaminophen)
Parasorbic acid
Parathion
Patulin
Penicillic acid
Pentachloroethane
Permethrin

3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3

48
31, Sup 7
94
19, Sup 7
9, Sup 7
61
13, Sup 7
47
68
73
10, Sup 7
30, Sup 7
40, Sup 7
10, Sup 7
41, Sup 7, 71
53

1990
1987
2010
1987
1987
1994
1987
1989
1997
1999
1987
1987
1987
1987
1999
1991

000129-20-4
012174-11-7
000103-90-2
010048-32-5
000056-38-2
000149-29-1
000090-65-3
000076-01-7
052645-53-1

Group

27

Volume

Year

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

Group

000198-55-0 Perylene
060102-37-6 Petasitenine
Petroleum solvents
000085-01-8 Phenanthrene
000156-51-4 Phenelzine sulfate
000103-03-7 Phenicarbazide
000108-95-2 Phenol
000050-33-9 Phenylbutazone
000108-45-2 meta-Phenylenediamine
000106-50-3 para-Phenylenediamine
000135-88-6 N-Phenyl-2-naphthylamine
000090-43-7 ortho-Phenylphenol
000213-46-7 Picene
001918-02-1 Picloram
000051-03-6 Piperonyl butoxide
009003-01-4 Polyacrylic acid
Polychlorinated dibenzo-para-dioxins (other than 2,3,7,8tetrachlorodibenzo-para-dioxin)
Polychlorinated dibenzofurans
(see 2,3,4,7,8-Pentachlorodibenzofuran)
009010-98-4 Polychloroprene
009002-88-4 Polyethylene
009016-87-9 Polymethylene polyphenyl isocyanate
009011-14-7 Polymethyl methacrylate
009003-07-0 Polypropylene
009003-53-6 Polystyrene
009002-84-0 Polytetrafluoroethylene
009009-54-5 Polyurethane foams
009003-20-7 Polyvinyl acetate
009002-89-5 Polyvinyl alcohol
009002-86-2 Polyvinyl chloride
009003-39-8 Polyvinyl pyrrolidone
004548-53-2 Ponceau SX
023746-34-1 Potassium bis(2-hydroxyethyl)dithiocarbamate
002955-38-6 Prazepam
029069-24-7 Prednimustine
000053-03-2 Prednisone
Printing inks
Proflavine salts

28

Volume

Year

3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3

92
31, Sup 7
47
92
24, Sup 7
12, Sup 7
47, 71
13, Sup 7
16, Sup 7
16, Sup 7
16, Sup 7
73
92
53
30, Sup 7
19, Sup 7
69

2010
1987
1989
2010
1987
1987
1999
1987
1987
1987
1987
1999
2010
1991
1987
1987
1997

69

1997

3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3

19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7
19, Sup 7, 71
8, Sup 7
12, Sup 7
66
50
26, Sup 7
65
24, Sup 7

1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1987
1996
1990
1987
1996
1987

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

000051-02-5
000122-42-9
000627-12-3
000115-07-1
087625-62-5

Pronetalol hydrochloride
Propham
n-Propyl carbamate
Propylene
Ptaquiloside
Pulp and paper manufacture
Pyrene
Pyridine
Pyrido[3,4-c]psoralen
Pyrimethamine
Quercetin
para-Quinone
Quintozene (Pentachloronitrobenzene)
Reserpine
Resorcinol
Retrorsine
Rhodamine B
Rhodamine 6G
Rifampicin
Ripazepam
Rosiglitazone
Rugulosin
Rock (stone) wool
Saccharated iron oxide
Saccharin and its salts
(NB: Overall evaluation downgraded to Group 3 with
supporting evidence from other relevant data)
Scarlet Red
Schistosoma mansoni (infection with)
Selenium and selenium compounds
Semicarbazide hydrochloride
Seneciphylline
Senkirkine
Sepiolite
Shikimic acid
Silica, amorphous
Simazine
Slag wool
Sodium chlorite

000129-00-0
000110-86-1
085878-62-2
000058-14-0
000117-39-5
000106-51-4
000082-68-8
000050-55-5
000108-46-3
000480-54-6
000081-88-9
000989-38-8
013292-46-1
026308-28-1
122320-73-4
023537-16-8
008047-67-4
000081-07-2

000085-83-6
007782-49-2
000563-41-7
000480-81-9
002318-18-5
015501-74-3
000138-59-0
007631-86-9
000122-34-9
007758-19-2

Group

29

Volume

Year

3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3

13, Sup 7
12, Sup 7
12, Sup 7
60
40, Sup 7
25, Sup 7
92
77
40, Sup 7
13, Sup 7
73
15, Sup 7, 71
5, Sup 7
24, Sup 7
15, Sup 7, 71
10, Sup 7
16, Sup 7
16, Sup 7
24, Sup 7
66
108
40, Sup 7
43, 81
2, Sup 7
73

1987
1987
1987
1994
1987
1987
2010
2000
1987
1987
1999
1999
1987
1987
1999
1987
1987
1987
1987
1996
in prep
1987
2002
1987
1999

3
3
3
3
3
3
3
3
3
3
3
3

8, Sup 7
61
9, Sup 7
12, Sup 7
10, Sup 7
31, Sup 7
68
40, Sup 7
68
73
43, 81
52

1987
1994
1987
1987
1987
1987
1997
1987
1997
1999
2002
1991

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

000148-18-5
000052-01-7
009003-54-7
009003-55-8
000108-30-5
000842-07-9
003118-97-6
000085-86-9
006416-57-5
006368-72-5
000127-69-5
000057-68-1

Sodium diethyldithiocarbamate
Spironolactone
Styrene-acrylonitrile copolymers
Styrene-butadiene copolymers
Succinic anhydride
Sudan I
Sudan II
Sudan III
Sudan Brown RR
Sudan Red 7B
Sulfafurazole (Sulfisoxazole)
Sulfamethazine
(NB: Overall evaluation downgraded to Group 3 with
supporting evidence from other relevant data)
Sulfamethoxazole
Sulfites
Sulfur dioxide
Sunset Yellow FCF
Surgical implants and other foreign bodies:
- Organic polymeric materials (as a group)
- Orthopaedic implants of complex composition
- Cardiac pacemakers
- Silicone breast implants
- Implanted foreign bodies of metallic chromium or
titanium and of cobalt-based, chromium-based and
titanium-based alloys, stainless steel and depleted
uranium
- Dental materials
- Ceramic implants
SV40 polyomavirus
Symphytine
Talc not containing asbestos or asbestiform fibres
Tannic acid and tannins
Tea
Temazepam
Terpene polychlorinates (Strobane)
2,2',5,5'-Tetrachlorobenzidine
Tetrachlorvinphos
Tetrakis(hydroxymethyl)phosphonium salts
Theobromine
Theophylline

000723-46-6
007446-09-5
002783-94-0

022571-95-5
014807-96-6
001401-55-4
000846-50-4
008001-50-1
015721-02-5
022248-79-9
000083-67-0
000058-55-9

Group

30

Volume

Year

3
3
3
3
3
3
3
3
3
3
3
3

12, Sup 7
79
19, Sup .7
19, Sup 7
15, Sup 7
8, Sup 7
8, Sup 7
8, Sup 7
8, Sup 7
8, Sup 7
24, Sup 7
79

1987
2001
1987
1987
1987
1987
1987
1987
1987
1987
1987
2001

3
3
3
3
3

79
54
54
8, Sup 7
74

2001
1992
1992
1987
1999

3
3
3
3
3
3
3
3
3
3
3
3

104
31, Sup 7
42, Sup 7, 93
10, Sup 7
51
66
5, Sup 7
27, Sup 7
30, Sup 7
48, 71
51
51

2013
1987
2010
1987
1991
1996
1987
1987
1987
1999
1991
1991

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

Group

000062-56-6
000137-26-8
000108-88-3
089778-26-7
000052-68-6
000545-06-2
000071-55-6
000079-00-5
000102-71-6
001954-28-5
001582-09-8
090370-29-9
000137-17-7
000088-05-1
003902-71-4
000118-96-7
000217-59-4
000068-76-8
000545-55-1
000051-18-3
000115-96-8
038571-73-2
000057-39-6
000128-66-5
000143-67-9
002068-78-2
009003-22-9
000075-35-4
009011-06-7
000075-38-7
000088-12-0
025013-15-4
012001-79-5
013983-17-0
001330-20-7
000095-68-1
000095-78-3
000085-84-7

Thiourea
Thiram
Toluene
Toremifene
Trichlorfon
Trichloroacetonitrile
1,1,1-Trichloroethane
1,1,2-Trichloroethane
Triethanolamine
Triethylene glycol diglycidyl ether
Trifluralin
4,4',6-Trimethylangelicin plus ultraviolet A radiation
2,4,5-Trimethylaniline
2,4,6-Trimethylaniline
4,5',8-Trimethylpsoralen
2,4,6-Trinitrotoluene
Triphenylene
Tris(aziridinyl)-para-benzoquinone (Triaziquone)
Tris(1-aziridinyl)phosphine oxide
2,4,6-Tris(1-aziridinyl)-s-triazine
Tris(2-chloroethyl) phosphate
1,2,3-Tris(chloromethoxy)propane
Tris(2-methyl-1-aziridinyl)phosphine oxide
Vat Yellow 4
Vinblastine sulfate
Vincristine sulfate
Vinyl chloride-vinyl acetate copolymers
Vinylidene chloride
Vinylidene chloride-vinyl chloride copolymers
Vinylidene fluoride
N-Vinyl-2-pyrrolidone
Vinyl toluene
Vitamin K substances
Wollastonite
Xylenes
2,4-Xylidine
2,5-Xylidine
Yellow AB

31

3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3

Volume
79
53
47, 71
66
30, Sup 7
52, 71
20, Sup 7, 71
52, 71
77
11, Sup 7, 71
53
Sup 7
27, Sup 7
27, Sup 7
40, Sup 7
65
92
9, Sup 7
9, Sup 7
9, Sup 7
48, 71
15, Sup 7, 71
9, Sup 7
48
26, Sup 7
26, Sup 7
19, Sup 7
39, Sup 7, 71
19, Sup 7
39, Sup 7, 71
19, Sup 7, 71
60
76
68
47, 71
16, Sup 7
16, Sup 7
8, Sup 7

Year
2001
1991
1999
1996
1987
1999
1999
1999
2000
1999
1991
1987
1987
1987
1987
1996
2010
1987
1987
1987
1999
1999
1987
1990
1987
1987
1987
1999
1987
1999
1999
1994
2000
1997
1999
1987
1987
1987

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

Agent

Group

000131-79-3 Yellow OB
000315-18-4 Zectran
001318-02-1 Zeolites other than erionite (clinoptilolite,
phillipsite,mordenite, non-fibrous Japanese zeolite,
synthetic zeolites)
012122-67-7 Zineb
000137-30-4 Ziram
000105-60-2 Caprolactam
000103-90-2 Acetaminophen (see Paracetamol)
Alpha particles (see Radionuclides)
012174-11-7 Attapulgite (see Palygorskite)
Beta particles (see Radionuclides)
000494-03-1 N,N-Bis(2-chloroethyl)-2-naphthylamine (see
Chlornaphazine)
000117-81-7 Bis(2-ethylhexyl) phthalate (see Di(2-ethylhexyl)
phthalate)
Boot and shoe manufacture and repair (see Leather dust,
Benzene)
000055-98-1 1,4-Butanediol dimethanesulfonate (see Busulfan)
Chimney sweeping (see Soot)
013909-09-6 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea
(Methyl-CCNU) (see Semustine)
000107-30-2 Chloromethyl methyl ether (see Bis(chloromethyl)ether;
chloromethyl methyl ether)
Chlorophenols (see Polychlorophenols)
001937-37-7 CI Direct Black 38 (see Benzidine, dyes metabolized to)
002602-46-2 CI Direct Blue 6 (see Benzidine, dyes metabolized to)
016071-86-6 CI Direct Brown 95 (see Benzidine, dyes metabolized to)
059865-13-3 Ciclosporin (see Cyclosporine)
008007-45-2 Coal tars (see Coal-tar distillation)
Continuous glass filament (see Glass filament)
001464-53-5 1,2:3,4-Diepoxybutane (see Monographs on 1,3Butadiene)
Diesel engine exhaust (see Engine exhaust, diesel)
Dyes metabolized to benzidine (see Benzidine, dyes
metabolized to)
Foreign bodies (see Surgical implants and other foreign
bodies)
Furniture and cabinet making (see Wood dust)
001303-00-0 Gallium arsenide (see Arsenic and inorganic arsenic
compounds)

32

Volume

Year

3
3
3

8, Sup 7
12, Sup 7
68

1987
1987
1997

3
3
4

12, Sup 7
53
39, Sup 7, 71

1987
1991
1999

25, Sup 7

1987

92

2010

35, Sup 7

1987

11, Sup 7

1987

25, Sup 7
86, 100C

1987
2012

Agents Classified by the IARC Monographs, Volumes 1109

CAS No

010043-66-0
000505-60-2
000055-98-1

000523-44-4
001936-15-8
000087-86-5
053973-98-1
007664-93-9
010098-97-2

014807-96-6

012070-12-1
007440-48-4

Agent

Group

Gamma-Radiation (see X- and Gamma-Radiation)

Gasoline engine exhaust (see Engine exhaust, gasoline)
High-temperature frying (see Frying)
Hot mate (see Mate, hot)
Household combustion of biomass fuel (see Biomass
fuel, indoor emissions from household combustion of)
Household combustion of coal (see Coal, indoor
emissions from household combustion)
Human herpesvirus type 4 (see Epstein-Barr virus)
Human herpesvirus type 8 (see Kaposi sarcoma
herpesvirus)
Involuntary smoking (see Tobacco smoke, second-hand)
Iodine-131 (see Radioiodines)
Mustard gas (see Sulfur mustard)
Myleran (see Busulfan)
Nickel refining (see Nickel compounds)
Oestrogen (see Estrogen)
Oral contraceptives, combined estrogen-progestogen
(see Estrogen-progestogen oral contraceptives)
Orange I (see CI Acid Orange 20)
Orange G (see CI Orange G)
Paving and roofing with coal-tar pitch (see Coal-tar pitch)
Pentachlorophenol (see Polychlorophenols)
Poligeenan (see Carrageenan, degraded)
Stress (see Volume 100)
Strong-inorganic-acid mists containing sulfuric acid (see
Acid mists)
Strontium-90 (see Fission products)
Sunlamps and sunbeds (see Ultraviolet-emitting tanning
devices)
Talc containing asbestiform fibres (see Asbestos)
Toxins derived from certain Fusarium species (see
Fusarium)
Tungsten carbide with cobalt metal (see Cobalt metal
with tungsten carbide)
Urethane (see Ethyl carbamate)
Wood smoke (see Biomass fuel, indoor emissions from
household combustion)

Last update: 31 March 2014

33

Volume

Year

11

1976

92
53, 71

2010
1999

42, Sup 7

1987