Specific Purpose/Topic: Cystic Fibrosis Opening with Impact: Can all of you please stand?

All of you represent the estimated 70,000 people in the world who have cystic fibrosis, or CF. Now, will all of you (motions to one row) please sit down? All of you still standing represent the 70% of people who are diagnosed with CF by the age of two. Okay, now will you guys (motion to two more rows) sit down, please? The rest of you are the 45% of the CF population who are 18 and older. Speaker Credibility = Statistic Slide: The median life expectancy of CF patients is 37, and many of these CF patients will not live past the age of 18. Those of you left standing represent the 50% of CF patients that are 18 and older, and those of you who are seated represent the other half of CF patients who, unfortunately, do not. Thank you. You all can sit down now. Thesis Statement: Today I will inform you about a disease called cystic fibrosis. By the end of my speech you will have more knowledge on the topic of cystic fibrosis. Connect with the Audience: By using the audience to display the important statistic, I established a connection and created relevancy to my topic, making the statistic real for the audience to heighten their interest and choice to listen to my speech. Preview of Main Points: What is Cystic Fibrosis? What Causes Cystic Fibrosis?

4 Transitions:

Body and Supporting Material = Main Points, sub-points displaying facts from research What is Cystic Fibrosis? o Lung disease o Coughing and shortness of breath o Salty skin What Causes Cystic Fibrosis? o Cystic fibrosis transmembrane conductance regulator (CFTR) o Mutations o Sweat o Lungs Treatments for Cystic Fibrosis o Goals

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To prevent more damage to the lungs, as well as treat them by monitoring nutrition and partaking in physical activity Antibiotic therapy Airway clearance More pulmonary therapy

Research of 4 Credible Sources: List sources in APA format (see Ch. 6 and Appendix A). Add a sentence about facts obtained from each source Internet o About Cystic Fibrosis (n.d.) Retrieved September 9, 2013, from www.cff.org/aboutcf/ Information from this website was used for information as to what cystic fibrosis is. Journal o Derichs, N (2013). Targeting a Genetic Defect: Cystic Fibrosis Transmembrane Conductance Regulator Modulators in Cystic Fibrosis. European Respiratory Review, (22), 58-65. Is used for information on what causes cystic fibrosis. Journal o Brown-Guttovs, H. (2008). Helping Patients Cope with Cystic Fibrosis. Nursing Made Incredibly Easy, (6), 48-54. Used to inform the audience of some treatments available to CF patients. e-Book o Amaral, M.D. & Kunzelmann, K. (2011). Cystic Fibrosis: Diagnosis and Protocols, Volume I: Approaches to Study and Correct CFTR Defects. Regensburg, Germany. Springer Protocols. Used for Opening with Impact and to show opening statistic.