FORWARD INQUIRIES TO:

Ed Roullard
Vice President, SAFC
+1 314.236.8717

MEDIA INQUIRIES TO:

Mr. Mark Button
Impress Public Relations
+1 408.310.2168
mark@impress-pr.com

SAFC SUPPLY SOLUTIONS INTRODUCES CERTIFIED ORGANICS TO

FLAVORS & FRAGRANCES PRODUCT LINE
Extends Industry-Leading Food-Grade, Halal and Kosher Raw Materials Catalog

St. Louis, MO – February 10, 2009 – SAFC Supply Solutions®, a business segment of
SAFC®, a member of the Sigma-Aldrich Group (NASDAQ: SIAL), and a leading supplier of
food-grade raw materials, today announced that it has added 50 new Certified Organics
products to its extensive Flavors & Fragrances raw materials product line. Details of the new
products are available in the new SAFC Supply Solutions Flavors and Fragrance
supplemental catalog or can be accessed immediately online at
www.safcsupplysolutions.com.

The new Organic products are certified by the Midwest Organic Services Association (MOSA)
and will meet both the U.S National Organic Program (NOP) and the European Organic
Standards. The Certified Organics are an extension of SAFC Supply Solutions’ existing 1700
high quality food-grade, Halal and Kosher certified products.

The organic food and beverage sector is expanding rapidly, with research indicating historical
US sales growth at over 20% annually in the $25 billion market1, with positive growth still
projected in 2009 despite a downturn in overall global economic conditions2.

“The introduction of our Certified Organic product line delivers a broad range of reliable,
ready-to-ship, high quality Food-Grade raw materials that are expected to help our customers
optimize the research, development and production of new taste technologies in the rapidly

1
SOURCE: Organic Trade Association
2
SOURCE: Organic Monitor
growing organic products market,” commented Dinh Phan, SAFC Flavors & Fragrances
Market Segment Manager. “Our broad range of Certified Organic products, worldwide delivery,
localized support network, compliance leadership and 24 hour access to regulatory
documentation on our website provide a total supply chain solution that can help control costs
while maintaining superior quality. The products are all available as prepackaged units ready
to ship on demand, an approach that we believe will provide greater flexibility and an ability for
our customers to bring new technologies to the market faster.”

Customers can request the new SAFC Supply Solutions Flavors & Fragrances supplemental
catalog by calling 1-800-227-4563, by email at ff@sial.com or online at
www.safcsupplysolutions.com.

- ENDS -

About SAFC: SAFC® is the custom manufacturing and services group within Sigma-Aldrich that
focuses on high-purity inorganics for high technology applications, cell culture products and services for
biopharmaceutical manufacturing, biochemical production and the manufacturing of complex, multi-step
organic synthesis of APIs and key intermediates. SAFC has manufacturing facilities around the world
dedicated to providing manufacturing services for companies requiring a reliable partner to produce
their custom manufactured materials. SAFC has four focus areas – SAFC Pharma™, SAFC Supply
Solutions®, SAFC Biosciences™, and SAFC Hitech™ – and had annual sales of nearly $600 million in
2007 SAFC is one of the world’s top 10 fine chemical businesses. For more information, visit
www.safcglobal.com.

About SAFC Supply Solutions: SAFC Supply Solutions offers a complete line of customized products
and services to alleviate issues associated with compliance, timely delivery, product reliability,
packaging customization, and quality assurance for regulated industries, including pharmaceutical
development, diagnostics manufacturing and flavors and fragrances. Our customized sourcing services,
with access to more than 100,000 starting materials, combined with expertise in analytical testing,
manufacturing, packaging, quality control, and compliance services can speed the development
process and lower costs for customers, enabling faster time to market. For more information visit
www.safcsupplysolutions.com.

About Sigma-Aldrich: Sigma-Aldrich® is a leading Life Science and High Technology company. Its
biochemical and organic chemical products and kits are used in scientific and genomic research,
biotechnology, pharmaceutical development, the diagnosis of disease and as key components in
pharmaceutical and other high technology manufacturing. The Company has customers in life science
companies, university and government institutions, hospitals, and in industry. Over one million scientists
and technologists use its products. Sigma-Aldrich operates in 37 countries and has 8,000 employees
providing excellent service worldwide. Sigma-Aldrich is committed to Accelerating Customer Success
through innovation and Leadership in Life Science, High Technology and Service. For more information
about Sigma-Aldrich, please visit its award-winning Web site at http://www.sigma-aldrich.com.

Cautionary Statement: This release contains forward-looking statements relating to future

performance, goals, strategic actions and initiatives and similar intentions and beliefs and other
statements regarding the Company’s expectations, goals, beliefs, intentions and the like, which involve
assumptions regarding the Company’s operations and conditions in the markets the Company serves.
The Company does not undertake any obligation to update these forward-looking statements.
SAFC®, SAFC Supply Solutions® and Sigma-Aldrich® are registered trademarks and SAFC Pharma™, SAFC Biosciences™ and
SAFC Hitech™ are trademarks of Sigma-Aldrich Biotechnology L.P. and Sigma-Aldrich Co.