Presented by

Amir Sadaula
BVSc & AH,8th sem
Rampur Campus
Roll No: 01
 Acute or chronic contagious disease
affecting domestic as well as wide range of
wild birds
 In acute form Septicemia condition with
high mortality
 The chronic form is also known as
“WATTLE Cholera”
 World-wide in distribution
 Pasteurella multocida
 gram –ve, non motile, non spore forming rod
shaped bacteria.
 organism appears bipolar in shape while stained
with methylene blue or Giemsa stain
 organism grows well on meat infusion broth
enriched with peptone and avium serum
 Gas –ve, Oxidase and Catalase test +ve
 organism killed with common disinfectant and
sunlight
 Direct contact between susceptible birds and
clinically affected or recovered carriers.
 Rodents, and wild birds are sources of indirect
infection. Contaminated
 Feed bags, equipment, and the clothing of
personnel may introduce infection into farm
 Intraflock transmission is enhanced by handling
birds for vaccination and weighing and by open
 watering systems such as troughs and bell drinkers.
 Per Acute: Death of large number of birds
 Acute : two type of manifestations
 Pulmonary form : respiratory of distress appearing as
sneezing, coughing and gasping, cyanosis prior to
death
 Septicemic form : fever, depression, anorexia,
discharge from mouth and ruffled feathers along with
diarrhea. Feces is watery in nature having whitish
appearance initially followed by greenish coloration
containing mucus
 Chronic form:
 hyperemia and edema of comb and wattles
 Joint may be swollen. Swellings pit on pressure.
Affection of the joint may lead to lameness.
 Mucoid discharge is noted in beak and nostrils.
 Exudation may appear from eye (Conjunctivitis) or
pharynx (pharyngitis).
 Infection spread in the bone of head and or brain
leading to in coordination, walking in circle and
torticolis
 Liver: Enlarged, focal area of coagulative necrosis,
massive white or greyish necrotic foci resemble pin
head
 Heart: pin point hemorrhage in fat
 Intestine: viscid mucus, petechial hemorrhage in
duodenum
 Lungs: Pneumonic change
 Ovary: follicle appear flaccid, congestion, egg
peritonitis
 Joints: Swollen containing exudate
 Comb and wattle: swollen unilateral or bilateral
 History and clinical finding
 Post Mortem finding
 Demonstration of Organism impression
smear of Liver or Blood staining with
Methylene blue Gram –ve Bipolar organism
 Serology: Whole Blood aggulutination,
AGDT
 Newcastle Disease
 Fowl plague/ Avian Influenza
 Vitamin A deficiency
 Fowl Coryza
 Salmonellosis
 Mycotoxicity
 CRD
 Gentamicin @ 1gm/2 ltr DW for 5 days
 Enrofloxacin @ 1ml/2 ltr DW for 5 days
 Doxycyclin @ 1gm/ltr DW for 5 days
 Neomycin + Doxycyclin @ 1gm/4 ltr DW for 5 days
 Sulphonamide @ 2.5- 5 gm/100 birds for 5 days
 Cholamphenicol @ 1 gm/5 ltr DW for 5 days
 Supportive therapy:
 Livertonic: 5 – 15 ml/100 birds for 7days
 Immunomodulator: 5-10 ml/100 birds for 7 days
 Vitamins: 5 – 15 ml/100 birds for 7 days
 Maintain good hygiene and sanitation
 Try to remove recovered which are carrier
 Biosecurity measure
 All in all out
 Vaccination:
 Live vaccine: strain of live P multocida found non
pathogenic CU strain
 Killed bacterins: preparation of one or more serotype
chemically inactivated and kept in oil emulsion.
 Commerical vaccine: FC inactivated vaccine
1st Vaccine @ 8 weeks or Older S/C
Repeat 6 week later S/C