Documentos de Académico
Documentos de Profesional
Documentos de Cultura
SCIENTIFIC INNOVATION:
ARTIFICIAL BLOOD
DOCENTE:
DOCENTE DRA. Rosa Gonzáles Llontop
ALUMNO:
Fallaque Ruiz Carlos Eduardo
CODIGO:
090631-F
CICLO: 2010- I
Medical English–FMH
Continually ask for blood donors, but these donations, though valuable, have a
number of risks to the recipient, including diseases such as hepatitis C or
HIV. Now, according to an article published May 10 in the online version of The
Guardian, Lance Twyman, a PhD from the University of Kent, working in his
laboratory at the University of Sheffield in the development of a new artificial
blood would be completely sterile and even could be manufactured in
dehydrated form. It would be easier to transport and store it in the future, simply
add water to obtain blood group 0 negative (universal donor).
Twyman has long been trying to create molecules that mimic nature and found
porphyrins, hollow square-shaped molecules that combine metals such as
iron. "Iron is found in the center of the molecule, as in the case of hemoglobin,"
says Twyman. However, although the hemoglobin in red blood cells containing
iron-based porphyrin to bind oxygen reversibly (ie, to capture the oxygen in the
lungs, transport and release in the tissues), porphyrin does not work alone, and
which ultimately react with oxygen rather than simply bind to it. Therefore,
according to Twyman, it is necessary to combine the chemistry of porphyrin
polymer chemistry for a molecule that mimics hemoglobin.
Página6
After five years of development, combining a porphyrin with monomers that self-
assemble in a tree structure, Twyman has achieved a molecule very similar to
hemoglobin in size and shape and also provides the right environment around
the porphyrin core to iron bind and release oxygen. The appearance of this
artificial blood is a dark red paste with the consistency of honey and water
soluble.
Medical English–FMH
The placing plastic blood in the body, even to save a life, sounds risky, but
Twyman said that porphyrins are natural. According to him, the polymer
component would be ignored by the human body's immune system and there
are medical uses today reaffirming its position, however, so far, his experiment
is limited to test tube.
Other researchers are skeptical and point out that much research remains
before we can say nothing.
universal).
El hecho de poner sangre plástica en el cuerpo, aunque sea para salvar una
vida, suena arriesgado, pero Twyman señala que las porfirinas son naturales.
Según él, el componente polimérico sería ignorado por sistema inmunológico
del cuerpo humano y existen usos médicos en la actualidad que reafirman su
postura; sin embargo, de momento, su experimento se limita a tubo de ensayo.
Continually ask for blood donors, but these donations, though valuable, have a
number of risks to the recipient. Now, according to an article by Lance Twyman
in the development of a new artificial blood that would be utterly futile and even
could be manufactured in dehydrated form.
Twyman has achieved a molecule very similar to hemoglobin in size and shape
and also provides the right environment around the porphyrin core for iron to
bind and release oxygen. The appearance of this artificial blood is a dark red
paste with the consistency of honey and water soluble.
One of the main applications would be the battlefield or in a place where there
has been a major disaster.
Página6
At present the major advantages of artificial blood body blood, either because
they are sterile, easy to use, and less expensive and produced in dry form.
In the porphyrin does not work alone, as it reacts with oxygen rather than simply
bind to it.
Twyman has achieved a molecule very similar to hemoglobin in size and shape,
which offers the right environment around the porphyrin core for iron to bind and
release oxygen.
One of the main applications would be the battlefield or in a place where there
has been a major disaster.
Página6