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Definitions
In normal circulation, pressure exerted by flow of blood through the heart and blood
vessel
High blood pressure can result from the changes in the cardiac output or changes in
peripheral resistance
Medication can use to treat HTN and decrease peripheral resistance
Blood volume is the strength and rate of the myocardial contraction
Blood Pressure = Cardiac Output x Peripheral Resistance
Cardiac Output = Heart Rate x Stroke Volume
Hypertension: AKA High blood pressure
Defined by the Seventh Report of the Joint National Commission on the Prevention,
Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7) as a systolic
pressure greater than 140 mm Hg and a diastolic pressure greater than 90 mm Hg,
based on the average of two or more accurate blood pressure measurements taken
during two or more contacts with a health care provider
Classification of Blood Pressure for Adults Age 18 and Older
Hypertension Treatment
1. Medication Treatment
a. Usually initial medication treatment is a thiazide diuretic.
b. Low doses are initiated and the medication dosage is increased gradually if blood
pressure does not reach target goal.
c. Additional medications are added if needed.
d. Multiple medications may be needed to control blood pressure.
e. Lifestyle changes initiated to control BP must be maintained.
Lifestyle Modifications
Cardiovascular II Page 1
Interventions
1. Patient teaching
2. Support adherence to the treatment regimen
3. Consultation/collaboration
4. Follow-up care
5. Emphasize control rather than cure
6. Reinforce and support lifestyle changes
7. A lifelong process
8. Objective is to lower B/P without adverse effects
Gerontologic Considerations
1. Noncompliance
2. Include family
3. Understanding of therapeutic regimen
a. Reading instructions
b. Monotherapy: placed on one drugs instead of a bunch of drugs
Cardiovascular II Page 2
Hypertensive Crises
1. Hypertensive emergency
a. Blood pressure >180/120 and must be lowered immediately to prevent damage
to target organs.
i. Can cause angina because heart is pumping harder
ii. Left ventricle works harder, can cause enlarged heart
b. Conditions includes
i. Pregnancy
ii. Acute myocardial infarction
iii. Dissecting aortic aneurysm
iv. Intracranial hemorrhage
c. Reduce BP 25% in first hour
d. Reduce to 160/100 over 6 hours
e. Then gradual reduction to normal over a period of days
f. Exceptions are ischemic stroke and aortic dissection
g. Medications
i. IV vasodilators: sodium nitroprusside, nicardipine, fenoldopam mesylate,
enalaprilat, nitroglycerin
1) Short acting drugs: takes minutes to 4 hours
2) May be used for initial treatment
h. Need very frequent monitoring of BP and cardiovascular status
2. Hypertensive urgency
a. Blood pressure is very high but no evidence of immediate or progressive target
organ damage.
b. Condition includes:
i. Severe HA
ii. Nosebleed
iii. Anxious
c. Patient requires close monitoring of blood pressure and cardiovascular status.
d. Assess for potential evidence of target organ damage.
e. Medications - Fast-acting oral agents:
i. Beta-adrenergic blocker- labetalol
ii. Angiotensin-converting enzyme inhibitors: captopril
iii. Alpha2-agonists-clonidine
Therapeutic goals are reduction of the mean blood pressure by up to 25% within 1st
hour of treatment
Further reduction of blood pressure is about 160/100 over a period of up to 6
hours
Gradual reduction of blood pressure is over a period of days
Exception of these goals are the treatment of ischemic stroke (ex. Aortic dissection)
You dont want B/P to stay elevated for long because it could rupture or can
cause a stroke