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Predisposing Factors:

Gender: Female
Age 51y.o.
Genetic/ Hereditary. (aunt
has breast cancer)

Precipitating Factors:
Diet
No checkup for treatment
Immunosuppression

Genetic mutation of the cellular

Activation of
growth-promoting
oncogenes

Inactivation of
tumor suppressor
genes

Alterations in the
gene that controls

Unregulated proliferation and


differentiation of cancer cells in the
Growth of a malignant

Activation of
immunologic
mechanism
Release of Blymphocytes, Tlymphocytes and
natural killer cells

Cancer cells

Impaired of the
immune response

Release of
growth factors
ANGIOGENE

Immunosuppres

Death of some
cancer cells

Malignant
tumor grows

Etoricoxib
90mg P.O

BID
Normal cells are
Inflammatory
Change in
Rapid
Malignant tumor
Sultamicillin
deprived of
response
symmetry
multiplication of
obstructs the milk
750mg P.Oor size
Unexplained
BID
weight loss
Release of
Tramadol
Accumulation of the
Fatigue
Rapid
metabolism
Rupture
of milk
Mastectomy
chemical
25mg PRN fluid, cells and
Limited
causedROM
by the
mediators;
cellular
Plasma
Vascular
Transient
fluid
of
(3/5)
cancer cells Compression
Pusdebris and
Pain
Inc.
Swelling
Bradykinins
and
live
anddecay
dead
Vasodilation
Tissue
the
leaks
permeability
nerve
vasoconstriction
into the

Vasodilatio
n
Blood and
lymph
stasis
Palpable, immovable,
Decrease
Malignant
tumor
hard
painless
nodes;
bloodand
supply
tends to compress
Supraclavicular
and
to
the breast
blood
and
axillary lymph nodes
(2cm)
Ischemia
Cancer cells begin
of
to Presence
spread locally
Foul Odor
Necrosis
Tissue
decay
cancer
cells in
via lymphatic