Exercise 9: Renal System Physiology: Activity 1: The Effect of Arteriole Radius on Glomerular Filtration Lab Report

Pre-lab Quiz Results

You scored 100% by answering 5 out of 5 questions correctly.

There are approximately __________ nephrons in a healthy human kidney. You correctly answered: c. 1 106

Which of the following lists the anatomical structures in the correct order as they are encountered by the blood and
filtered fluid during the process of filtration?

You correctly answered: d. afferent arteriole, glomerular capillary, Bowman's capsule

Bowman's capsule is connected to the beginning of the

You correctly answered: b. proximal convoluted tubule.

The functional unit of the kidney is the You correctly answered: c. nephron.

During the process of renal reabsorption, fluid and solutes move from the You correctly answered: b. renal tubule into
the peritubular capillaries.

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Experiment Results Predict Question:

Predict Question 1: What will happen to the glomerular capillary pressure and filtration rate if you decrease the radius of the
afferent arteriole?

Your answer : b. Both pressure and filtration rate will decrease.

Predict Question 2: What will happen to the glomerular capillary pressure and filtration rate if you increase the radius of the afferent
arteriole?

Your answer : a. Both pressure and filtration rate will increase.

Predict Question 3: What will happen to the glomerular capillary pressure and filtration rate if you decrease the radius of the
efferent arteriole?

Your answer : a. Both pressure and filtration rate will increase.

Stop & Think Questions:

Caffeine consumption leads to increased urine formation. From the results in this experiment thus far, you might propose that

You correctly answered: d. caffeine dilates the afferent arteriole.

When you are in the desert and dehydrating, which of the following arteriole combinations would benefit you the most? You
correctly answered: c. afferent constriction and efferent dilation

Experiment Data:

Afferent Radius
Efferent Radius
Beaker Press.

Glomerular Press.
Glom. Filt. Rate
Urine Volume
(mm)
(mm)
(mm Hg)
(mm Hg)
(ml/min)
(ml)
0.50
0.45
90
55.08
124.99
200.44

0.45
0.45
90
51.54
81.06
179.88
0.40

0.45
90
48.52
43.66
143.91

0.35
0.45
90
46.16
14.35
76.33
0.55
0.45
90
58.94
172.86
212.87

0.60
0.45
90
62.88
221.69
220.74
0.50
0.45
90
55.08
124.99
200.44

0.50
0.40
90
56.10
137.69
227.49
0.50
0.35
90
56.84

146.82
247.96

0.50
0.30
90
57.34
152.96
262.23

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Post-lab Quiz Results

You scored 100% by answering 4 out of 4 questions correctly.

If you increase the afferent arteriole radius and keep all other variables constant, the glomerular filtration rate would You
correctly answered: a. increase.

If you decrease the efferent arteriole radius and keep all other variables constant, the volume of urine flowing into the
urinary bladder would

You correctly answered: a. increase.

If you increase the efferent arteriole radius and keep all other variables constant, the glomerular filtration rate would You
correctly answered: b. decrease.

If you decrease the afferent arteriole radius and keep all other variables constant, the volume of urine flowing into the
urinary bladder would __________.

You correctly answered: b. decrease.

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Review Sheet Results

1. What are two primary functions of the kidney? Your answer:

Como organo de regulacion y excrecion tiene las funciones de :

Filtrar el agua y los solutos de la sangre, eliminando los desechos metabolicos y materiales extraos.

regular la osmolaridad del plasma, el volumen plasmatico, el equilibrio acido-base del organismo y el equilibrio
hidroelectrolitico del organismo.

What are the components of the renal corpuscle? Your answer:

El glomerulo y la capsula de Bowman

Starting with the renal corpuscle, list the components of the renal tubule as they are encountered by filtrate. Your answer:

Son los siguientes:

Corpusculo renal,

Tubo contorneado proximal

Asa de henle

Tubo contorneado distal

Conducto colector

Describe the effect of decreasing the afferent arteriole radius on glomerular capillary pressure and filtration rate. How well
did the results compare with your prediction?

Your answer:

Al disminuir el radio de la arteriola aferente, disminuyo la presin del capilar glomerular y la tasa de filtracin glomerular. La
prediccion fue correcta.

Describe the effect of increasing the afferent arteriole radius on glomerular capillary pressure and filtration rate. How well
did the results compare with your prediction?

Your answer:

Al aumentar el radio de la arteriola aferente, aumento la presin del capilar glomerular y la tasa de filtracin glomerular. La
prediccion fue correcta.

Describe the effect of decreasing the efferent arteriole radius on glomerular capillary pressure and filtration rate. How well
did the results compare with your prediction?

Your answer:

Al disminuir el radio de la arteriola eferente, se incremento la presin del capilar glomerular y la tasa de filtracin. La
prediccion fue correcta.

Describe the effect of increasing the efferent radius on glomerular capillary pressure and filtration rate.

Your answer:

Al aumentar el radio de la arteriola eferente, disminuyen la presin del capilar glomerular y la tasa de filtracin.

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