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S/N Structure IUPAC Name Mol. Formula Mol.

Weight Code
1

(S)-6,7-dimethoxy-3-((R)-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro-
C22H23NO7 413.4 GSU 000
[1,3]dioxolo[4,5-
g]isoquinolin-5-
yl)isobenzofuran-1(3H)-one

Noscapine
2

(R)-5-((S)-4,5-dimethoxy-
1,3-dihydroisobenzofuran-
1-yl)-4-methoxy-6-methyl-
C22H25NO6 399.4 GSU001
5,6,7,8-tetrahydro-
[1,3]dioxolo[4,5-
g]isoquinoline

Red-Noscapine
3

(S)-3-((R)-9-bromo-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro-
EM011
[1,3]dioxolo[4,5- C22H22BrNO7 492.3
GSU002
g]isoquinolin-5-yl)-6,7-
dimethoxyisobenzofuran-
1(3H)-one

Bromo Noscapine
4

(R)-9-bromo-5-((S)-4,5-
dimethoxy-1,3-
dihydroisobenzofuran-1-
yl)-4-methoxy-6-methyl- C22H24BrNO6 478.3 GSU003
5,6,7,8-tetrahydro-
[1,3]dioxolo[4,5-
g]isoquinoline

Red-Br-NOS
5

(S)-3-((R)-9-chloro-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro-
EM015
[1,3]dioxolo[4,5- C22H22ClNO7 447.9
GSU004
g]isoquinolin-5-yl)-6,7-
dimethoxyisobenzofuran-
1(3H)-one

Chloro-NOS
6

(S)-4-bromo-3-((R)-9-iodo-
4-methoxy-6-methyl-
5,6,7,8-tetrahydro-
[1,3]dioxolo[4,5- C22H21BrINO7 618.2 GSU005
g]isoquinolin-5-yl)-6,7-
dimethoxyisobenzofuran-
1(3H)-one

Iodo-NOS
7

(S)-3-((R)-9-fluoro-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro-
[1,3]dioxolo[4,5- C22H22FNO7 431.4 GSU006
g]isoquinolin-5-yl)-6,7-
dimethoxyisobenzofuran-
1(3H)-one

Fluoro-NOS
8

(R)-5-((S)-4,5-dimethoxy-
1,3-dihydroisobenzofuran-
1-yl)-9-fluoro-4-methoxy-6-
C22H24FNO6 417.4 GSU007
methyl-5,6,7,8-tetrahydro-
[1,3]dioxolo[4,5-
g]isoquinoline

CEFNA
9

3-((R)-9-(benzylamino)-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro-
[1,3]dioxolo[4,5- C29H30N2O7 518.6 GSU008
g]isoquinolin-5-yl)-6,7-
dimethoxyisobenzofuran-
1(3H)-one

9-Bn-NH2-NOS
10

(S)-3-((R)-9-amino-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro-
[1,3]dioxolo[4,5- C22H24N2O7 428.4 GSU009
g]isoquinolin-5-yl)-6,7-
dimethoxyisobenzofuran-
1(3H)-one

9-Amino-NOS I
11

(R)-3-((R)-9-amino-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro-
[1,3]dioxolo[4,5- C22H24N2O7 428.4 GSU010
g]isoquinolin-5-yl)-6,7-
dimethoxyisobenzofuran-
1(3H)-one

9-Amino-NOS II
12

1-benzyl-3-((R)-5-((S)-4,5-
dimethoxy-3-oxo-1,3-
dihydroisobenzofuran-1-
yl)-4-methoxy-6-methyl- C30H31N3O8 561.6 GSU011
5,6,7,8-tetrahydro-
[1,3]dioxolo[4,5-
g]isoquinolin-9-yl)urea

9-BenzylUrea-NOS I
13

1-benzyl-3-((R)-5-((R)-4,5-
dimethoxy-3-oxo-1,3-
dihydroisobenzofuran-1-
yl)-4-methoxy-6-methyl- C30H31N3O8 561.6 GSU012
5,6,7,8-tetrahydro-
[1,3]dioxolo[4,5-
g]isoquinolin-9-yl)urea

9-BenzylUrea NOS II
14

1-((5R)-5-(4,5-dimethoxy-
3-oxo-1,3-
dihydroisobenzofuran-1-
yl)-4-methoxy-6-methyl-
C29H29N3O7S 563.6 GSU013
5,6,7,8-tetrahydro-
[1,3]dioxolo[4,5-
g]isoquinolin-9-yl)-3-
phenylthiourea

9-Phenylthiourea-NOS
15

(S)-3-((R)-9-bromo-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro-
[1,3]dioxolo[4,5-
C21H20BrNO7 478.3 GSU014
g]isoquinolin-5-yl)-7-
hydroxy-6-
methoxyisobenzofuran-
1(3H)-one

9-Br-7-OH NOS
16

(S)-4-bromo-3-((R)-9-
bromo-4-methoxy-6-
methyl-5,6,7,8-tetrahydro-
[1,3]dioxolo[4,5-
C21H19Br2NO7 557.2 GSU015
g]isoquinolin-5-yl)-7-
hydroxy-6-
methoxyisobenzofuran-
1(3H)-one

Dibromo-7-OH-NOS
17

(S)-7-(benzylamino)-4-
bromo-3-((R)-9-bromo-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro-
C28H26Br2N2O6 646.3 GSU016
[1,3]dioxolo[4,5-
g]isoquinolin-5-yl)-6-
methoxyisobenzofuran-
1(3H)-one

Dibromo7-NHBn-NOS
18

(S)-1-((R)-9-bromo-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro-
[1,3]dioxolo[4,5-
C24H25BrN2O8 549.4 GSU017
g]isoquinolin-5-yl)-5-
methoxy-3-oxo-1,3-
dihydroisobenzofuran-4-yl
ethylcarbamate

9-Br-EthylCarba-NOS
19

(S)-1-((R)-9-bromo-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro-
[1,3]dioxolo[4,5-
C29H27BrN2O8 611.4 GSU018
g]isoquinolin-5-yl)-5-
methoxy-3-oxo-1,3-
dihydroisobenzofuran-4-yl
benzylcarbamate

9-Br-7-Benzylcarba-NOS
20

(S)-1-((R)-9-bromo-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro-
[1,3]dioxolo[4,5-
C23H22BrNO8 520.3 GSU019
g]isoquinolin-5-yl)-5-
methoxy-3-oxo-1,3-
dihydroisobenzofuran-4-yl
acetate

9-Br-7-Acetyl-NOS
21

(S)-3-((R)-9-chloro-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro-
[1,3]dioxolo[4,5-
C21H20ClNO7 433.8 GSU020
g]isoquinolin-5-yl)-7-
hydroxy-6-
methoxyisobenzofuran-
1(3H)-one

9-Cl-7-OH-NOS
22

(S)-1-((R)-9-chloro-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro-
[1,3]dioxolo[4,5-
C23H22ClNO8 475.9 GSU021
g]isoquinolin-5-yl)-5-
methoxy-3-oxo-1,3-
dihydroisobenzofuran-4-yl
acetate

9-Cl-7-Acetyl-NOS
23

(R)-N-benzyl-5-((S)-4,5-
dimethoxy-1,3-
dihydroisobenzofuran-1-
yl)-4-methoxy-6-methyl- C29H32N2O6 504.6 GSU022
5,6,7,8-tetrahydro-
[1,3]dioxolo[4,5-
g]isoquinolin-9-amine

Reduced-9-BnNH2-NOS
24

(R)-5-((S)-4,5-dimethoxy-
1,3-dihydroisobenzofuran-
1-yl)-4-methoxy-6-methyl-
C22H26N2O6 414.5 GSU023
5,6,7,8-tetrahydro-
[1,3]dioxolo[4,5-
g]isoquinolin-9-amine

Reduced-9-Amino-NOS
25

(S)-7-hydroxy-6-methoxy-
3-((R)-4-methoxy-6-
methyl-5,6,7,8-tetrahydro-
C21H21NO7 399.4 GSU024
[1,3]dioxolo[4,5-
g]isoquinolin-5-
yl)isobenzofuran-1(3H)-one

7-OH-NOS
26

(S)-5-methoxy-1-((R)-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro-
[1,3]dioxolo[4,5- C23H23NO8 441.4 GSU025
g]isoquinolin-5-yl)-3-oxo-
1,3-dihydroisobenzofuran-
4-yl acetate

7-Acetyl-NOS
27

(S)-5-methoxy-1-((R)-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro-
[1,3]dioxolo[4,5- C28H25NO8 503.5 GSU026
g]isoquinolin-5-yl)-3-oxo-
1,3-dihydroisobenzofuran-
4-yl benzoate

7-Benzoyl-NOS
28

(S)-5-methoxy-1-((R)-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro-
[1,3]dioxolo[4,5- C24H26N2O8 470.5 GSU027
g]isoquinolin-5-yl)-3-oxo-
1,3-dihydroisobenzofuran-
4-yl ethylcarbamate

29

(S)-5-methoxy-1-((R)-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro-
[1,3]dioxolo[4,5- C28H26N2O8 518.5 GSU028
g]isoquinolin-5-yl)-3-oxo-
1,3-dihydroisobenzofuran-
4-yl phenylcarbamate

7-Phenylcarba-NOS
30

(S)-5-methoxy-1-((R)-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro-
[1,3]dioxolo[4,5- C29H28N2O8 532.5 GSU029
g]isoquinolin-5-yl)-3-oxo-
1,3-dihydroisobenzofuran-
4-yl benzylcarbamate

7-Benzylcarba-NOS
31

(S)-5-methoxy-1-((R)-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro-
[1,3]dioxolo[4,5- C22H20F3NO9S 531.5 GSU030
g]isoquinolin-5-yl)-3-oxo-
1,3-dihydroisobenzofuran-
4-yl methanesulfonate

7-Triflic-NOS
32

(S)-7-(benzylamino)-6-
methoxy-3-((R)-4-
methoxy-6-methyl-5,6,7,8-
tetrahydro- C28H28N2O6 488.5 GSU031
[1,3]dioxolo[4,5-
g]isoquinolin-5-
yl)isobenzofuran-1(3H)-one

7-NHBn-NOS
33

(S)-7-amino-6-methoxy-3-
((R)-4-methoxy-6-methyl-
5,6,7,8-tetrahydro-
C21H22N2O6 398.4 GSU032
[1,3]dioxolo[4,5-
g]isoquinolin-5-
yl)isobenzofuran-1(3H)-one

7-Amino-NOS
34

35

36