11/06/14

Scientific Investigation

You and your partner are scientific researchers. You have just
discovered a DNA sequence that may be important in explaining
several medical conditions. The normal DNA sequence is given below.
ACAAGATGC
Answer the questions below to read the sequence. Does the
gene message make sense?
A(1) is the first letter of the answer to this question: What is the name of the base
that bonds with Adenine?
C(1) is the first letter of the answer to this question: What is the name of the
particle shown under the positive mutation section?
A(2) is the letter e
A(3) is the first letter of the answer to this question: What is the name of the base
that bonds with Guanine?
G(1) is the letter a
A(4) is the same as A(1)
T(1) is the first letter of the word that fills in the blank:_______ has shown that
the more complex the organism, the more junk DNA is present.
G(2) is the same as G(1)
C(2) is the letter n

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Here is the same DNA sequence, with three different mutations, each
implicated in a different medical condition. Identify each type of each
mutation as either deletion, addition or substitution.
Normal:
ACAAGATGC
Medical Condition A:
ACTAGATGC
Medical Condition B:
ACAAGAATGC
Medical Condition C:
ACAGATGC

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You and your partner discover that the following DNA sequence
may be implicated in Alzheimers disease.
GCCTCCTGCTGCCGAT
Answer the questions below to read the sequence. Does the
gene message make sense? If you discover that the gene is
mutated, identify the type of mutation.
G(1) is the third letter of the word that fills in the blank: Negative ________
reduce the probability that organisms with the mutation will produce
offspring or survive in their environment.
C(1) is the letter h
C(2) is the letter e
T(1) is the first letter of the word that fills in the blank: When an extra base
is added, this is called _________ .
C(3) is d
C(4) is the second letter of the second word that fills in the blank: An
__________ __________ is taken into the body and delivers the
healthy gene to cells affected by cystic fibrosis.

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T(2) is the first letter of the second word that fills in the blank: The
________ ________ will be useful only if the geneticist can shoot the
arrow the inactive virus into the nuclei of millions of target cells.
G(2) is the last letter of the word used to fill in the blank: By genetically
altering white blood cells called T-lymphocytes, researchers have been able
to increase the ability of a cancer patients immune system to fight
advanced ________.
C(5) is the letter t
T(3) is the last letter of the third word that fills in the blank: People who
carry the ________ _______ _______ have red blood cells that are Cshaped.
G(3) is the letter t
C(6) is the first letter of the first word used to fill in the blank: Cigarette
smoke, radiation from x-rays or UV rays, pollutants such as mercury, and
even ________ _________ are examples of environmental mutagens that
can cause mutations.
C(7) is the letter e
G(4) is the letter r
A(1) is the first letter of the chemical used to control pests.
T(4) is the last letter of the word that fills in the blank: A few individuals
have been found to be _____ to the HIV virus and, therefore, to AIDS.