PROGNOSIS WORKSHEET

Citation:
Are the results of this prognosis stud !alid"
Was a defined, representative sample of
patients assembled at a common (usually
early) point in the course of their disease?
Was patient follow-up sufficiently long
and complete?
Were objective outcome criteria applied
in a blind fashion?
f subgroups with different prognoses are
identified, was there adjustment for
important prognostic factors?
Was there validation in an independent
group (test set) of patients?
Are the !alid results of this prognosis stud i#portant"
!ow li"ely are the outcomes over time?
!ow precise are the prognostic
estimates?
If ou $ant to %al%ulate a %onfiden%e inter!al around the #easure of prognosis:
Clini%al &easure Standard Error 'SE( Tpi%al Cal%ulation of CI
#roportion (as in the rate
of some
prognostic event,
etc$) where%
the number of patients & n
the proportion of these patients
who e'perience the event & p
{ } n p p ( ) ) (
where p is proportion
and n is number of
patients
f p & *+(,- & -$+ (or +-.)
and n & ,-
/0 & { } ,- ( ) + $ - ) ( + $ -
& -$-,1 (or ,$1.)
23. 4 is +-. 5 )$2, 6 ,$1.
or *7$,. to 3*$+.
n from your evidence% 888
p from your evidence% 888
9our calculation%
/0% 888888888888
23. 4% 88888888
Can ou appl this !alid) i#portant e!iden%e a*out prognosis in %aring for our
patient"
Were the study patients similar to your
own?
Will this evidence ma"e a clinically
important impact on your
conclusions about what to offer or
tell your patient?
Additional notes: