Pharma Solution Center MCQs

MCQs with Answer

Pharma Solution Center provide MCQs related to GPAT and other pharma compitative Examinations. Hope that youll find this usefull. Thank You. Vineet Sharma 10/23/2013

Pharma Solution Center 1.A carbohydrate, known commonly as invert sugar, is (A) Fructose (B) Sucrose (C) Glucose (D) Lactose 2.A suicide enzyme is (A) Cycloxygenase (B) Lipooxygenase (C) Phospholipase A1 (D) Phospholipase A2 3.In the biosynthesis of cholesterol, the rate limiting enzyme is (A) Mevalonate kinase (B) HMG-CoA synthetase (C) HMG-CoA reductase (D) Cis-prenyl transferase 4.Surface-active agents are (a) Form a multimolecular, strong, rigid film around the dispersed droplets. (b) Adsorbed at oil/water interfaces to form monomolecular films and reduce interfacial tension. (c) Adsorbed at the interphase and form film of particles around the dispersed globules. (d) Increase mutual solubility of oil and water. 5.Which of the following drug contain yohimbin nucleus(a) Belladonna (b) Pilocarpus (c) Lobelia (d) Rauwolfia 6.Purine alkaloid contain which of the following two rings(a) Imidazoline & pyrimidine ring (b) Imidazolidine & pyridazine ring (c) Imidazole & pyridazine ring (d) Imidazole & pyrimidine ring 7.Example for live vaccine is a. Rubella & BCG b. Polio & TAB c. Diphtheria & Tetanus d. Hepatitis A & Rabies 8.Antibodies in our body are produced by a. B-lymphocytes b. T-lymphocytes c. Monocytes d. RBCs 9.Which of the following is correct:(a) Aspartame is 500 times sweeter than saccharin. (b) Aspartame is stable at higher ph in presence of moisture 2 www.facebook.com/pharmasolutioncenter Pharmasolutioncenter@gmail.com

Pharma Solution Center (c) Aspartame is made up of amino acid phenylalanine & aspartic acid (d) Aspartame is bitter after taste and has been reported to be carcinogenic 10.The sterilizing agent is a. Ethelene oxide b. Oxygen c. Nitrogen d. Carbon tetrachloride 11.Congential diseases are a. Diseases present at birth b. Deficiency disease c. Occur during life d. Spread from one individual to another 12.Lysol is a a. Sterilent b. Disinfectant c. Antiseptic d. Antifungal agent 13.The symbol Rx is printed on the label of which type of medicine (a) Medicines belonging to schedule G (b) Medicines belonging to schedule H (c) Medicines belonging to schedule X (d) medicines belonging to schedule V 14.Aspirin prolongs bleeding time by inhibiting the synthesis of: (a) Clotting factors in liver (b) Prostacyclin in vascular endothelium (c) Cyclic AMP in platelets (d) Thromboxane A2 in platelets 15.Which of the following properties is desirable in a pharmaceutical suspension? I. Caking; II. Pseudoplastic flow; III. Thixotropy Choose the correct option (a) I only (b) III only (c) I and III only (d) II and III only 16.Alcohol drinking is associated with which of the following changes in serum lipid concentrations (a) Decreased HDL cholesterol (b) Increased LDL cholesterol (c) Decreased VLDL cholesterol (d) Increased HDL cholesterol 17.BET equation defines (a) Absorption 3 www.facebook.com/pharmasolutioncenter Pharmasolutioncenter@gmail.com

Pharma Solution Center (b) Adsorption (c) Assimilation (d) Diffusion 18.Carrs consolidation index = (a) (Tapped density Fluff density) / Tapped density x 100 (b) (Tapped density Fluff density) / Fluff density x 100 (c) (Fluff density Tapped density) / Tapped density x 100 (d) (Fluff density Tapped density) / Fluff density x 100 19.Sodium valproate act by (a) Blocking the metabolic of GABA (b) Blocking the GABA receptor (c) Blocking the conduction of impulses in brain (d) Blocking the release of GABA 20.Schedule FF contains the list of the following (a) Drugs which can be marketed under generic names only (b) Drugs which are habit forming (c) Standards for ophthalmic prepration (d) Drugs which can be exempt from certain provisions 21.Nu-Tab is :a)95%Sucrose +4%invert sugar b) 93%Sucrose +7%invert sugar% c) 97%Sucrose +3%invert sugar d) None of the above 22. All of the following are released as prohormones except:A) vitamin D B)Steroid C)Insulin D)Parathyroid 23.The Drugs and Cosmetics Act has been divided into ............... parts: A)15 B)24 C)16 D)18 24.Veegum is hydrocolloid and its origin is: A) Plant B)Minerals C)Synthetic D)Semi-synthetic 25.The Number of Peaks given by the Proton NMR spectrum of 2-methyl-1-pentene:A)4 B)5 4 www.facebook.com/pharmasolutioncenter Pharmasolutioncenter@gmail.com

Pharma Solution Center C)6 D)3 26.Conductance cell for conductivity measurements can be made from two of the following metals :P) Mercury Q) Sodium R)Platinum S) Stainless still Identify correct pair A)P,R B)Q,S C)R,S D)P,Q 27.for thermophilic microorganism ,minimum growth temp required is A.20^c B.37^c C.45^c D.65^c 28.R.W.C is used to identify A.antibiotic B.antipyretic C.antiseptic D.none 29.varicella zoster causative organism for A.small pox B.herpes C.dermatophytosis D.none 30.organism causes meningitis belongs to A.candida B.neisseria C.pseudomonas D.clostridium 31.pharmacogenomics is A. Study of idiosyncratic reactn. B. Study of route of drug administratn C. Study of SAR D. Study of assay method 32.to understand the drug receptor interaction it is necessary to quantify relation b/w. A. Drug and its toxicity b. Drug and absorption c. Drug and biological effct d. None 33.recepor demonstrates fastest onset of response,when stimulated... A.nuclear receptor 5 www.facebook.com/pharmasolutioncenter Pharmasolutioncenter@gmail.com

Pharma Solution Center b.ionotropic c.g protein coupled d.insulin 34.prodrug of terbutaline a.zafirlukast b.salmaterol c.bambuterol d.none 35.SELECT UNWANTED EFFCT OF L-DOPA A.DEMENTIA B.HYPERTENSION C.DYSKINESIA D.EXCITOTOXICITY 36.Which conversion is a accomplished during glycolysis (a) glycogen to glucose (b) pyruvate to glucose (c) glucose to glycogen (d) glucose to pyruvate 37.Which would be best to separate a protein that binds strongly to its substrate (a) Gel filtration (b) Affinity chromatography (c) Cation exchange (d) Ion exchange 38.Select a fat-soluble vitamin: (a) Ascorbic acid (b) Tocopherol (c) Thiamine (d) Riboflavin 39.Which would be best to separate a protein that binds strongly to its substrate (a) Gel filtration (b) Affinity chromatography (c) Cation exchange (d) Ion exchange 40.Which of the following vitamins is also known as an antisterility factor (a) Vitamin E (b) Vitamin B6 (c) Vitamin B1 (d) Vitamin 41.As per DOT regulations, temperature of the aerosol product before it emerges from the Leak Test Tank is (a) 100c (b) 1000C (c) 130 f 6 www.facebook.com/pharmasolutioncenter Pharmasolutioncenter@gmail.com

Pharma Solution Center (d) 1300C 42.Gram (-) bacteria produces Endotoxins that are chemically a.pyrogens b.lipopolysaccarides c.both d.none 43.Which of the following antienzymes is a carbonic anhydrase inhibitor (a) Physostigmine (b) Selegiline (c) Aminocaproic acid (d) Acetazolamide 43.Which of the following natural drug is used as rodenticide(a) Derris (b) Pyrethrum (c) Red squill (d) Nicotine 44.Antibiotic which interacts with calcium ion (a) Erythromycin (b) Streptomycin (c) Tetracycline (d) Ampicillin 45.Store in a cool place means (a) 0-2C (b)2-8C (c) 8-25C (d) less than 0C 46.Which one of the folloing is commonly use as target material for generation of X ray (a) Cu (b) Fe (c) Au (d) Mo 47.Government opium factory is situated ata) Ghazipur b) lucknow c) srinagar d) Calcutta 48.Nebulizer? A. Division of sample solution B. Sample solution divided into fine droplets C. Used in aerosol as a droplet D. All of the above

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Pharma Solution Center 49.Schedule T deals with ____ A. Requirement of factory premises for manufacture of Homoeopathic preparation B. Requirement of factory premises and hygienic conditions C. Requirement of factory premises for manufacture of cosmetics D. All of the above 50.Laurocapram has application in ____ A. Increases solubility B. Penetration enhancer C. Wetting agent D. Improve absorption 51.Clays are ___________ A. Inorganic materials B. Suspending agent C. Dispersing agent D. Viscosity-increasing agent 52.the phenomenon Churg-strauss is the side effect of? A. Cortecosteroids B. Anticholinerics C. COX inhibitors D. Leukotriene antagonists 53.Silylating agents are used to _____ A. Make the stationary Phase polar B. Make the stationary Phase non-polar C. Both A & B D. None of the above 54.H2 blocker CIMETIDINE contains which ring in its structure? A. Benzimidazole B. Imidazole C. Thiazole D. Furan 55.Cholera red reaction is identified by A)Sulphuric acid B)Nitric acid C)Hydrochloric acid D)Carbolic acid 56.The detector used in ion chromatographyA) Flame ionization B) Flame photometer C) Electron capture D) Conductivity 57.Material used for construction of closure isA) Cork B) Rubber and metals 8 www.facebook.com/pharmasolutioncenter Pharmasolutioncenter@gmail.com

Pharma Solution Center C)Glass and plastics D) All the above 58.Lucky-nut tree is also known as _____ A. Cochineal B. Digitalis C. Thevita D. Rhubarb 59.To test the presence of Proteins, which test can be applied? A. Salkowski test B. Juglone test C. Dam- Karrer test D. Xanthoproteic test 60.Glycyrrhiza uralensis is an adulterant of ______ A. Yasti B. Cantharides C. Cascara D. None of the above 61.Which of the following non-opioid analgesic is a prodrug? a. Ketorolac b. Celecoxib c. Nabumetone d. Piroxicam 62.Inverse agonist of benzodiazepine receptor is a. Phenobarbitone b. Flumazenil c. Beta-carbolinet d. Gabapentin 63.The symptom "general feeling of illness and discomfort" is called a) cystitis b) malaise c) anaphylactic shock d) arthritis 64. Lipophilicity of surface active agent is increased bya) increasing alkyl chain b) including carboxylic group c) including alcoholic group d) none 65. Section-14 of the factories Act state thata) effective measures should be taken by the employer to keep workrooms free from dust and flame b) a factory must be fenced by safegaurds of substantial constitution c) adequate arrangement should be made for running canteens and dispensary for employees d) aseptic environment should be maintained around manufacture process 66. A 55 years old executive has cardiomyopathy and congestive heart failure. He is being treated with diuretics. The mechanism of action of furosemide is best described as-

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Pharma Solution Center

a) interference with H+ and HCO3 exchange b) Blockade of Na+/K+/2Cl- transporters c) blockade of a Na+ /Cl- cotransporter d) blockade of carbonic anhydrase e) inhibition of genetic expression of DNA in the kidney 67. Cyclizine is synthesized from a) methyl piperazine & benzyhydryl chloride b) methy piperazine & parachloro benzhydryl chloride c) piperazine & benzhydryl chloride d) methyl piperazine & m mehtyl benzyl piperazine 68. The glycosaminoglycan which dose not contain uronic acid is a) Dermatan sulphate b) chondroitin sulphate c) keratan sulphate d) heparan sulphate 69. The absorbed energy can be lost by which process a) production of heat b) decomposition into new species c) emission of radiation d) all of the above 70. In the presence of inflammation, the following are raised: a. platelets b. ferritin c. caeruloplasmin d. fibrinogen e. complement proteins 71. A technique of staining in which gram-positive bacterium is differentiated from gram-negative bacteria by Gram staining. This is because its cell wall contains ____ A. Lysozyme B. Teichoic acid C. Membrane protwins D. Lipid A 72. In the production of transgenic plants, the gene transfer is carried out by ______ A. Induction of meristematic primordial B. Gel filteration C. Clonal propagation D. Silicon carbide whiskers 73. A naturally occuring amino acid which does not have a chiral centre is ____ A. Glycine B. Alanine C. Tryptophan D. Tyrosine 74. 3,4 Benzpyrene present in cigarette smoke reduces the therapeutic activity of diazepam by ______ A. Altering excretion B. Binding to plasma proteins C. Inhibiting metabolism D. Increasing the activity of liver microsomal enzymes

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Pharma Solution Center 75. Genetically modified species of Papaver namely Papaver bracteatum and Papaver orientale
contain the predominant alkaloid __ A. Morphine B. Codeine C. Narcotine D. Thebaine

Thank you. By: Vineet Sharma For contact mail us at: Pharmasolutioncenter@gmail.com www.facebook.com/pharmasolutioncenter www.pharmasolutioncenter.blogspot.in

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