MITOSIS / MEIOSIS

Marcia Puchi 2011

Divisin nuclear

Divisin citoplasmtica

MEIOSIS

Fecundacin

2n

Apareamiento entrecruzamiento Permutacin

The two daughter cells contain a haploid number of chromosomes (but a diploid amount of DNA)

Dos principales fuentes de variabilidad durante la meiosis

2n different haploid gametes

223 = 8.4 106

On average, between two and three crossover events occur on each pair of human chromosomes

Entrecruzamiento

Recombinacin, complejos enzimticos que cortan, sintetizan y unen.

Errores en la meiosis: No disyuncin de los cromosomas a) Sndrome de Down (47 cromosomas): trisoma del par 21 b) Sndrome de Klinefelter (47 cromosomas): XXY c) Sndrome de Turner (45 cromosomas): XO
The frequency of missegregation in human oocytes is remarkably high (about 10% of meioses), and this is thought to be one reason for the high rate of spontaneous abortions in early pregnancy. The error rate increases with advancing maternal age

FECUNDACIN

Ovognesis

Entrada en fase M meiosis

the primary oocytes synthesize a coat and cortical granules

Seal hormonal