Some ADHD medicines may increase psychosis more than others, ‘real-world’ data show

Young adults treated for ADHD may be at a higher risk of having a psychotic event if they are given medicines such as Adderall and Vyvanse, a study found.
Source: Robert Bukaty/AP

Adolescents and young adults being treated for attention-deficit hyperactivity disorder may be at a higher risk of having a psychotic event if they are provided amphetamine medicines, such as Adderall and Vyvanse, instead of medications based on the compound methylphenidate, such as Ritalin or Concerta, according to a study published Wednesday.

The risk of psychosis was generally low, occurring in one in 660 patients, according to the study, which was published in the New England Journal of Medicine.

The risk is “low enough that you can’t say,

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